Compile Data Set for Download or QSAR
maximum 50k data
Found 355 Enz. Inhib. hit(s) with all data for entry = 3381
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398134(4-chloro-1-(oxetan-3-yl)-N-(spiro[2.5]octan-5-ylme...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398117(4-chloro-1-(oxetan-3-yl)-N-((1-(4-phenylpiperazin-...)
Affinity DataIC50: <10nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398146(4-Chloro-1-oxetan-3-yl-1H-indole-3-carboxylic acid...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398147(4-chloro-N-((1-hydroxy-3-methylcyclohexyl)methyl)-...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398154(Preparations of 4-chloro-N-(((1S,3S)-1-hydroxy-3-m...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398157(4-chloro-N-(((1R,3R)-1-hydroxy-3-methylcyclohexyl)...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398215((S)-4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398217(4-chloro-N-((3, 3-difluoro-1-hydroxycyclohexyl)met...)
Affinity DataIC50: <10nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398218(4-chloro-N-((3,3-difluorocyclohexyl)methyl)-1-(pyr...)
Affinity DataIC50: <10nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398219(4-chloro-N-((3,3-difluoro-5-methylcyclohexyl)methy...)
Affinity DataIC50: <10nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398220(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-((1-...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398220(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-((1-...)
Affinity DataIC50: <10nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398224(US10323000, Compound 163)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398233(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-(pip...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398233(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-(pip...)
Affinity DataIC50: <10nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398259(4-chloro-N-((4, 4-difluorocyclohexyl)methyl)-1-(1-...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398261(4-Chloro-1-dimethylcarbamoylmethyl-1H-indole-3-car...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398263(4-Chloro-1-dimethylcarbamoylmethyl-1H-indole-3-car...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398071(US10323000, Compound 7 | US10676433, Compound 7)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398073(4-Chloro-1-(3,3-difluoro-propyl)-1H-indole-3-carbo...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398085((R)-4-chloro-N-((3,3-difluoro-1-hydroxycyclohexyl)...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398106(Preparations of 4-chloro-N-((4,4-difluorocyclohexy...)
Affinity DataIC50: <10nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398141(4-Chloro-1-oxetan-3-yl-1H-indole-3-carboxylic acid...)
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398133(4-chloro-N—(((S)-3, 3-difluorocyclohexyl)meth...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398133(4-chloro-N—(((S)-3, 3-difluorocyclohexyl)meth...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398134(4-chloro-1-(oxetan-3-yl)-N-(spiro[2.5]octan-5-ylme...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398135(4-chloro-N-((3, 3-difluorocyclohexyl)methyl)-1-(ox...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398136(4-Chloro-1-oxetan-3-yl-1H-indole-3-carboxylic acid...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398141(4-Chloro-1-oxetan-3-yl-1H-indole-3-carboxylic acid...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398147(4-chloro-N-((1-hydroxy-3-methylcyclohexyl)methyl)-...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398149((S)-4-chloro-N-((3,3-difluoro-1-hydroxycyclohexyl)...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398149((S)-4-chloro-N-((3,3-difluoro-1-hydroxycyclohexyl)...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398150(4-chloro-N-((3,3-difluoro-1-hydroxycyclohexyl)meth...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398150(4-chloro-N-((3,3-difluoro-1-hydroxycyclohexyl)meth...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398154(Preparations of 4-chloro-N-(((1S,3S)-1-hydroxy-3-m...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398155(4-chloro-N-((3,3-difluoro-5-(trifluoromethyl) cycl...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398156(4-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl)meth...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398157(4-chloro-N-(((1R,3R)-1-hydroxy-3-methylcyclohexyl)...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398158(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-(oxe...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398158(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-(oxe...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398159(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-(2-(...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398168(4-Chloro-1-(tetrahydro-furan-3-yl)-1H-indole-3-car...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398170(4-Chloro-1-(tetrahydro-furan-3-yl)-1H-indole-3-car...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398171(4-Chloro-1-(tetrahydro-furan-3-yl)-1H-indole-3-car...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398175(4-Chloro-1-(tetrahydro-furan-3-yl)-1H-indole-3-car...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398176(4-chloro-N-(((1R,3R)-1-hydroxy-3-methyl cyclohexyl...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398176(4-chloro-N-(((1R,3R)-1-hydroxy-3-methyl cyclohexyl...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398177(4-chloro-N-((4, 4-difluorocyclohexyl)methyl)-1-(te...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398179(US10323000, Compound 116 | US10676433, Compound 11...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 beta(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398179(US10323000, Compound 116 | US10676433, Compound 11...)
Affinity DataIC50:  55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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