BindingDB logo
myBDB logout

Patent code US10329256

Compile Data Set for Download or QSAR
Found 159 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
55n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
55n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
55n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
55n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
55n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
550n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
550n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
550n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+3n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+3n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+3n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+3n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
5.50E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
5.50E+4n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+5n/an/an/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256482
PNG
(US10329256, Example 27 | US9487512, 27 | US9944601...)
Show SMILES Fc1ccccc1COc1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H27FN2O/c23-21-4-2-1-3-18(21)15-26-19-7-5-17(6-8-19)20-13-22(20)25-14-16-9-11-24-12-10-16/h1-8,16,20,22,24-25H,9-15H2/t20-,22+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 22n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256484
PNG
(US10329256, Example 29 | US9487512, 29 | US9944601...)
Show SMILES COc1ccc(NS(C)(=O)=O)cc1-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C22H29N3O3S/c1-28-22-8-7-18(25-29(2,26)27)13-20(22)16-5-3-15(4-6-16)19-14-21(19)24-17-9-11-23-12-10-17/h3-8,13,17,19,21,23-25H,9-12,14H2,1-2H3/t19-,21+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 23n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256498
PNG
(US10329256, Example 43 | US9487512, 43 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1cccnc1)C1CCNCC1
Show InChI InChI=1/C20H25N3/c1-2-18(14-22-9-1)16-3-5-17(6-4-16)19-12-20(19)23-13-15-7-10-21-11-8-15/h1-6,9,14-15,19-21,23H,7-8,10-13H2/t19-,20+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 32n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256481
PNG
(US10329256, Example 26 | US9487512, 26 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNC1
Show InChI InChI=1/C14H20N2/c1-2-4-12(5-3-1)13-8-14(13)16-10-11-6-7-15-9-11/h1-5,11,13-16H,6-10H2/t11?,13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 35n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256497
PNG
(US10329256, Example 42 | US9487512, 42 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)C1CC1)C1CCNCC1
Show InChI InChI=1/C18H26N2/c1-2-14(1)15-3-5-16(6-4-15)17-11-18(17)20-12-13-7-9-19-10-8-13/h3-6,13-14,17-20H,1-2,7-12H2/t17-,18+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 37n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 38n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256475
PNG
(US10329256, Example 20 | US9487512, 20 | US9944601...)
Show SMILES Fc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C14H19FN2/c15-13-4-2-1-3-11(13)12-9-14(12)17-10-5-7-16-8-6-10/h1-4,10,12,14,16-17H,5-9H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 38n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256486
PNG
(US10329256, Example 31 | US9487512, 31 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CNC1
Show InChI InChI=1/C13H18N2/c1-2-4-11(5-3-1)12-6-13(12)15-9-10-7-14-8-10/h1-5,10,12-15H,6-9H2/t12-,13+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 42n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 42n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256479
PNG
(US10329256, Example 24 | US9487512, 24 | US9944601...)
Show SMILES C1C(NC2CCNCC2)C1c1ccc2ccccc2c1
Show InChI InChI=1/C18H22N2/c1-2-4-14-11-15(6-5-13(14)3-1)17-12-18(17)20-16-7-9-19-10-8-16/h1-6,11,16-20H,7-10,12H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 47n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256470
PNG
(US10329256, Example 15 | US9487512, 15 | US9944601...)
Show SMILES C1[C@H](NC2CC3(C2)CCNCC3)[C@H]1c1ccccc1
Show InChI InChI=1/C17H24N2/c1-2-4-13(5-3-1)15-10-16(15)19-14-11-17(12-14)6-8-18-9-7-17/h1-5,14-16,18-19H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 48n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 56n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256491
PNG
(US10329256, Example 36 | US9487512, 36 | US9944601...)
Show SMILES CC1(C)CC(CC(C)(C)N1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C18H28N2/c1-17(2)11-14(12-18(3,4)20-17)19-16-10-15(16)13-8-6-5-7-9-13/h5-9,14-16,19-20H,10-12H2,1-4H3/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 68n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256468
PNG
(US10329256, Example 13 | US9487512, 13 | US9944601...)
Show SMILES C1[C@H](NC2CC3CCC(C2)N3)[C@H]1c1ccccc1
Show InChI InChI=1/C16H22N2/c1-2-4-11(5-3-1)15-10-16(15)18-14-8-12-6-7-13(9-14)17-12/h1-5,12-18H,6-10H2/t12?,13?,14?,15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 69n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256469
PNG
(US10329256, Example 14 | US9487512, 14 | US9944601...)
Show SMILES C1[C@H](NC2CCC3(CCNCC3)CC2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H28N2/c1-2-4-15(5-3-1)17-14-18(17)21-16-6-8-19(9-7-16)10-12-20-13-11-19/h1-5,16-18,20-21H,6-14H2/t17-,18+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 71n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256499
PNG
(US10329256, Example 44 | US9487512, 44 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1ccn[nH]1)C1CCNCC1
Show InChI InChI=1/C18H24N4/c1-3-15(17-7-10-21-22-17)4-2-14(1)16-11-18(16)20-12-13-5-8-19-9-6-13/h1-4,7,10,13,16,18-20H,5-6,8-9,11-12H2,(H,21,22)/t16-,18+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 72n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256473
PNG
(US10329256, Example 18 | US9487512, 18 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cncs1
Show InChI InChI=1/C11H17N3S/c1-3-12-4-2-8(1)14-10-5-9(10)11-6-13-7-15-11/h6-10,12,14H,1-5H2/t9-,10-/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 81n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256483
PNG
(US10329256, Example 28 | US9487512, 28 | US9944601...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H25F3N2/c23-22(24,25)19-3-1-2-18(12-19)16-4-6-17(7-5-16)20-13-21(20)27-14-15-8-10-26-11-9-15/h1-7,12,15,20-21,26-27H,8-11,13-14H2/t20-,21+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 84n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256480
PNG
(US10329256, Example 25 | US9487512, 25 | US9944601...)
Show SMILES CC1(CC1NC1CCNCC1)c1ccccc1
Show InChI InChI=1/C15H22N2/c1-15(12-5-3-2-4-6-12)11-14(15)17-13-7-9-16-10-8-13/h2-6,13-14,16-17H,7-11H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 97n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256489
PNG
(US10329256, Example 34 | US9487512, 34 | US9944601...)
Show SMILES NC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C15H20BrN3O/c16-11-3-1-10(2-4-11)13-9-14(13)18-12-5-7-19(8-6-12)15(17)20/h1-4,12-14,18H,5-9H2,(H2,17,20)/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 104n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256474
PNG
(US10329256, Example 19 | US9487512, 19 | US9944601...)
Show SMILES Cc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2/c1-11-4-2-3-5-13(11)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 105n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256472
PNG
(US10329256, Example 17 | US9487512, 17 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cccnc1
Show InChI InChI=1/C13H19N3/c1-2-10(9-15-5-1)12-8-13(12)16-11-3-6-14-7-4-11/h1-2,5,9,11-14,16H,3-4,6-8H2/t12-,13+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 107n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256493
PNG
(US10329256, Example 38 | US9487512, 38 | US9944601...)
Show SMILES CC(C)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C17H26N2/c1-13(2)19-10-8-15(9-11-19)18-17-12-16(17)14-6-4-3-5-7-14/h3-7,13,15-18H,8-12H2,1-2H3/t16-,17+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 108n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256477
PNG
(US10329256, Example 22 | US9487512, 22 | US9944601...)
Show SMILES COc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2O/c1-18-13-4-2-11(3-5-13)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 111n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256485
PNG
(US10329256, Example 30 | US9487512, 30 | US9944601...)
Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C23H31N3O2S/c1-16(2)29(27,28)26-21-5-3-4-19(14-21)17-6-8-18(9-7-17)22-15-23(22)25-20-10-12-24-13-11-20/h3-9,14,16,20,22-26H,10-13,15H2,1-2H3/t22-,23+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 111n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 111n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256465
PNG
(US10329256, Example 10 | US9487512, 10 | US9944601...)
Show SMILES C1[C@H](NC2CCCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-5-11(6-3-1)13-9-14(13)16-12-7-4-8-15-10-12/h1-3,5-6,12-16H,4,7-10H2/t12?,13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 119n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256476
PNG
(US10329256, Example 21 | US9487512, 21 | US9944601...)
Show SMILES Fc1ccc(cc1F)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H18F2N2/c15-12-2-1-9(7-13(12)16)11-8-14(11)18-10-3-5-17-6-4-10/h1-2,7,10-11,14,17-18H,3-6,8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 127n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256471
PNG
(US10329256, Example 16 | US9487512, 16 | US9944601...)
Show SMILES C1[C@H](NC2CCNC3CCCCC23)[C@H]1c1ccccc1
Show InChI InChI=1/C18H26N2/c1-2-6-13(7-3-1)15-12-18(15)20-17-10-11-19-16-9-5-4-8-14(16)17/h1-3,6-7,14-20H,4-5,8-12H2/t14?,15-,16?,17?,18+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 139n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256492
PNG
(US10329256, Example 37 | US9487512, 37 | US9944601...)
Show SMILES CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2/c1-17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 153n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256496
PNG
(US10329256, Example 41 | US9487512, 41 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCS(=O)(=O)CC1
Show InChI InChI=1/C14H18BrNO2S/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-19(17,18)8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 177n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256495
PNG
(US10329256, Example 40 | US9487512, 40 | US9944601...)
Show SMILES C1[C@H](NC2CCN(CC2)c2ccncc2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H23N3/c1-2-4-15(5-3-1)18-14-19(18)21-16-8-12-22(13-9-16)17-6-10-20-11-7-17/h1-7,10-11,16,18-19,21H,8-9,12-14H2/t18-,19+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 188n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256488
PNG
(US10329256, Example 33 | US9487512, 33 | US9944601...)
Show SMILES CC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C16H21BrN2O/c1-11(20)19-8-6-14(7-9-19)18-16-10-15(16)12-2-4-13(17)5-3-12/h2-5,14-16,18H,6-10H2,1H3/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 212n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 296n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 491n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256490
PNG
(US10329256, Example 35 | US9487512, 35 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C14H18BrNO/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-17-8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 549n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 700n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256466
PNG
(US10329256, Example 11 | US9487512, 11 | US9944601...)
Show SMILES C1[C@H](NC2CCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C13H18N2/c1-2-4-10(5-3-1)12-8-13(12)15-11-6-7-14-9-11/h1-5,11-15H,6-9H2/t11?,12-,13+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 908n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256483
PNG
(US10329256, Example 28 | US9487512, 28 | US9944601...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H25F3N2/c23-22(24,25)19-3-1-2-18(12-19)16-4-6-17(7-5-16)20-13-21(20)27-14-15-8-10-26-11-9-15/h1-7,12,15,20-21,26-27H,8-11,13-14H2/t20-,21+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.02E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256487
PNG
(US10329256, Example 32 | US9487512, 32 | US9944601...)
Show SMILES CS(=O)(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2O2S/c1-20(18,19)17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.68E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256467
PNG
(US10329256, Example 12 | US9487512, 12 | US9944601...)
Show SMILES C1[C@H](NC2CNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C12H16N2/c1-2-4-9(5-3-1)11-6-12(11)14-10-7-13-8-10/h1-5,10-14H,6-8H2/t11-,12+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.94E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.18E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.18E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256482
PNG
(US10329256, Example 27 | US9487512, 27 | US9944601...)
Show SMILES Fc1ccccc1COc1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H27FN2O/c23-21-4-2-1-3-18(21)15-26-19-7-5-17(6-8-19)20-13-22(20)25-14-16-9-11-24-12-10-16/h1-8,16,20,22,24-25H,9-15H2/t20-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.58E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256497
PNG
(US10329256, Example 42 | US9487512, 42 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)C1CC1)C1CCNCC1
Show InChI InChI=1/C18H26N2/c1-2-14(1)15-3-5-16(6-4-15)17-11-18(17)20-12-13-7-9-19-10-8-13/h3-6,13-14,17-20H,1-2,7-12H2/t17-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.79E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256494
PNG
(US10329256, Example 39 | US9487512, 39 | US9944601...)
Show SMILES FC(F)(F)CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H21F3N2/c17-16(18,19)11-21-8-6-13(7-9-21)20-15-10-14(15)12-4-2-1-3-5-12/h1-5,13-15,20H,6-11H2/t14-,15+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.50E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256482
PNG
(US10329256, Example 27 | US9487512, 27 | US9944601...)
Show SMILES Fc1ccccc1COc1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H27FN2O/c23-21-4-2-1-3-18(21)15-26-19-7-5-17(6-8-19)20-13-22(20)25-14-16-9-11-24-12-10-16/h1-8,16,20,22,24-25H,9-15H2/t20-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.01E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.60E+3n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.01E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256483
PNG
(US10329256, Example 28 | US9487512, 28 | US9944601...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1
Show InChI InChI=1/C22H25F3N2/c23-22(24,25)19-3-1-2-18(12-19)16-4-6-17(7-5-16)20-13-21(20)27-14-15-8-10-26-11-9-15/h1-7,12,15,20-21,26-27H,8-11,13-14H2/t20-,21+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.16E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256464
PNG
(US10329256, Example 9 | US9487512, 9 | US9944601, ...)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)[C@H]1C[C@@H]1NCCC1CCOCC1
Show InChI InChI=1/C22H26ClNO/c23-20-7-5-18(6-8-20)17-1-3-19(4-2-17)21-15-22(21)24-12-9-16-10-13-25-14-11-16/h1-8,16,21-22,24H,9-15H2/t21-,22+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.46E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256479
PNG
(US10329256, Example 24 | US9487512, 24 | US9944601...)
Show SMILES C1C(NC2CCNCC2)C1c1ccc2ccccc2c1
Show InChI InChI=1/C18H22N2/c1-2-4-14-11-15(6-5-13(14)3-1)17-12-18(17)20-16-7-9-19-10-8-16/h1-6,11,16-20H,7-10,12H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.51E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256496
PNG
(US10329256, Example 41 | US9487512, 41 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCS(=O)(=O)CC1
Show InChI InChI=1/C14H18BrNO2S/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-19(17,18)8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.69E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256490
PNG
(US10329256, Example 35 | US9487512, 35 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C14H18BrNO/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-17-8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.87E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256481
PNG
(US10329256, Example 26 | US9487512, 26 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNC1
Show InChI InChI=1/C14H20N2/c1-2-4-12(5-3-1)13-8-14(13)16-10-11-6-7-15-9-11/h1-5,11,13-16H,6-10H2/t11?,13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.08E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256467
PNG
(US10329256, Example 12 | US9487512, 12 | US9944601...)
Show SMILES C1[C@H](NC2CNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C12H16N2/c1-2-4-9(5-3-1)11-6-12(11)14-10-7-13-8-10/h1-5,10-14H,6-8H2/t11-,12+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.38E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256486
PNG
(US10329256, Example 31 | US9487512, 31 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CNC1
Show InChI InChI=1/C13H18N2/c1-2-4-11(5-3-1)12-6-13(12)15-9-10-7-14-8-10/h1-5,10,12-15H,6-9H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.55E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256465
PNG
(US10329256, Example 10 | US9487512, 10 | US9944601...)
Show SMILES C1[C@H](NC2CCCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-5-11(6-3-1)13-9-14(13)16-12-7-4-8-15-10-12/h1-3,5-6,12-16H,4,7-10H2/t12?,13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.65E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256489
PNG
(US10329256, Example 34 | US9487512, 34 | US9944601...)
Show SMILES NC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C15H20BrN3O/c16-11-3-1-10(2-4-11)13-9-14(13)18-12-5-7-19(8-6-12)15(17)20/h1-4,12-14,18H,5-9H2,(H2,17,20)/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.24E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256462
PNG
(US10329256, Example 7 | US9487512, 7 | US9944601, ...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cn1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C20H21F3N2O/c21-20(22,23)15-3-1-2-13(10-15)18-5-4-14(12-24-18)17-11-19(17)25-16-6-8-26-9-7-16/h1-5,10,12,16-17,19,25H,6-9,11H2/t17-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.35E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256489
PNG
(US10329256, Example 34 | US9487512, 34 | US9944601...)
Show SMILES NC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C15H20BrN3O/c16-11-3-1-10(2-4-11)13-9-14(13)18-12-5-7-19(8-6-12)15(17)20/h1-4,12-14,18H,5-9H2,(H2,17,20)/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.41E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 3.54E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256495
PNG
(US10329256, Example 40 | US9487512, 40 | US9944601...)
Show SMILES C1[C@H](NC2CCN(CC2)c2ccncc2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H23N3/c1-2-4-15(5-3-1)18-14-19(18)21-16-8-12-22(13-9-16)17-6-10-20-11-7-17/h1-7,10-11,16,18-19,21H,8-9,12-14H2/t18-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.60E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256466
PNG
(US10329256, Example 11 | US9487512, 11 | US9944601...)
Show SMILES C1[C@H](NC2CCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C13H18N2/c1-2-4-10(5-3-1)12-8-13(12)15-11-6-7-14-9-11/h1-5,11-15H,6-9H2/t11?,12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.77E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256461
PNG
(US10329256, Example 6 | US9487512, 6 | US9944601, ...)
Show SMILES C(CC1CCNCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H24N2/c1-2-4-14(5-3-1)15-12-16(15)18-11-8-13-6-9-17-10-7-13/h1-5,13,15-18H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.83E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM388464
PNG
(US10329256, Example 4 | US9944601, Example 4)
Show SMILES C(Oc1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1)c1ccccc1
Show InChI InChI=1S/C21H26N2O/c1-2-4-16(5-3-1)15-24-19-8-6-17(7-9-19)20-14-21(20)23-18-10-12-22-13-11-18/h1-9,18,20-23H,10-15H2/t20-,21+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.99E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256498
PNG
(US10329256, Example 43 | US9487512, 43 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1cccnc1)C1CCNCC1
Show InChI InChI=1/C20H25N3/c1-2-18(14-22-9-1)16-3-5-17(6-4-16)19-12-20(19)23-13-15-7-10-21-11-8-15/h1-6,9,14-15,19-21,23H,7-8,10-13H2/t19-,20+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.31E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256490
PNG
(US10329256, Example 35 | US9487512, 35 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCOCC1
Show InChI InChI=1/C14H18BrNO/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-17-8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.54E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256466
PNG
(US10329256, Example 11 | US9487512, 11 | US9944601...)
Show SMILES C1[C@H](NC2CCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C13H18N2/c1-2-4-10(5-3-1)12-8-13(12)15-11-6-7-14-9-11/h1-5,11-15H,6-9H2/t11?,12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.68E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256496
PNG
(US10329256, Example 41 | US9487512, 41 | US9944601...)
Show SMILES Brc1ccc(cc1)[C@H]1C[C@@H]1NC1CCS(=O)(=O)CC1
Show InChI InChI=1/C14H18BrNO2S/c15-11-3-1-10(2-4-11)13-9-14(13)16-12-5-7-19(17,18)8-6-12/h1-4,12-14,16H,5-9H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>5.00E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256469
PNG
(US10329256, Example 14 | US9487512, 14 | US9944601...)
Show SMILES C1[C@H](NC2CCC3(CCNCC3)CC2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H28N2/c1-2-4-15(5-3-1)17-14-18(17)21-16-6-8-19(9-7-16)10-12-20-13-11-19/h1-5,16-18,20-21H,6-14H2/t17-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.43E+4n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256492
PNG
(US10329256, Example 37 | US9487512, 37 | US9944601...)
Show SMILES CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2/c1-17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256471
PNG
(US10329256, Example 16 | US9487512, 16 | US9944601...)
Show SMILES C1[C@H](NC2CCNC3CCCCC23)[C@H]1c1ccccc1
Show InChI InChI=1/C18H26N2/c1-2-6-13(7-3-1)15-12-18(15)20-17-10-11-19-16-9-5-4-8-14(16)17/h1-3,6-7,14-20H,4-5,8-12H2/t14?,15-,16?,17?,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256478
PNG
(US10329256, Example 23 | US9487512, 23 | US9944601...)
Show SMILES Oc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H20N2O/c17-12-3-1-10(2-4-12)13-9-14(13)16-11-5-7-15-8-6-11/h1-4,11,13-17H,5-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256487
PNG
(US10329256, Example 32 | US9487512, 32 | US9944601...)
Show SMILES CS(=O)(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2O2S/c1-20(18,19)17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256491
PNG
(US10329256, Example 36 | US9487512, 36 | US9944601...)
Show SMILES CC1(C)CC(CC(C)(C)N1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C18H28N2/c1-17(2)11-14(12-18(3,4)20-17)19-16-10-15(16)13-8-6-5-7-9-13/h5-9,14-16,19-20H,10-12H2,1-4H3/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256494
PNG
(US10329256, Example 39 | US9487512, 39 | US9944601...)
Show SMILES FC(F)(F)CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H21F3N2/c17-16(18,19)11-21-8-6-13(7-9-21)20-15-10-14(15)12-4-2-1-3-5-12/h1-5,13-15,20H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256476
PNG
(US10329256, Example 21 | US9487512, 21 | US9944601...)
Show SMILES Fc1ccc(cc1F)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H18F2N2/c15-12-2-1-9(7-13(12)16)11-8-14(11)18-10-3-5-17-6-4-10/h1-2,7,10-11,14,17-18H,3-6,8H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256499
PNG
(US10329256, Example 44 | US9487512, 44 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1ccn[nH]1)C1CCNCC1
Show InChI InChI=1/C18H24N4/c1-3-15(17-7-10-21-22-17)4-2-14(1)16-11-18(16)20-12-13-5-8-19-9-6-13/h1-4,7,10,13,16,18-20H,5-6,8-9,11-12H2,(H,21,22)/t16-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256468
PNG
(US10329256, Example 13 | US9487512, 13 | US9944601...)
Show SMILES C1[C@H](NC2CC3CCC(C2)N3)[C@H]1c1ccccc1
Show InChI InChI=1/C16H22N2/c1-2-4-11(5-3-1)15-10-16(15)18-14-8-12-6-7-13(9-14)17-12/h1-5,12-18H,6-10H2/t12?,13?,14?,15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256473
PNG
(US10329256, Example 18 | US9487512, 18 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cncs1
Show InChI InChI=1/C11H17N3S/c1-3-12-4-2-8(1)14-10-5-9(10)11-6-13-7-15-11/h6-10,12,14H,1-5H2/t9-,10-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256491
PNG
(US10329256, Example 36 | US9487512, 36 | US9944601...)
Show SMILES CC1(C)CC(CC(C)(C)N1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C18H28N2/c1-17(2)11-14(12-18(3,4)20-17)19-16-10-15(16)13-8-6-5-7-9-13/h5-9,14-16,19-20H,10-12H2,1-4H3/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256470
PNG
(US10329256, Example 15 | US9487512, 15 | US9944601...)
Show SMILES C1[C@H](NC2CC3(C2)CCNCC3)[C@H]1c1ccccc1
Show InChI InChI=1/C17H24N2/c1-2-4-13(5-3-1)15-10-16(15)19-14-11-17(12-14)6-8-18-9-7-17/h1-5,14-16,18-19H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256467
PNG
(US10329256, Example 12 | US9487512, 12 | US9944601...)
Show SMILES C1[C@H](NC2CNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C12H16N2/c1-2-4-9(5-3-1)11-6-12(11)14-10-7-13-8-10/h1-5,10-14H,6-8H2/t11-,12+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256486
PNG
(US10329256, Example 31 | US9487512, 31 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CNC1
Show InChI InChI=1/C13H18N2/c1-2-4-11(5-3-1)12-6-13(12)15-9-10-7-14-8-10/h1-5,10,12-15H,6-9H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256475
PNG
(US10329256, Example 20 | US9487512, 20 | US9944601...)
Show SMILES Fc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C14H19FN2/c15-13-4-2-1-3-11(13)12-9-14(12)17-10-5-7-16-8-6-10/h1-4,10,12,14,16-17H,5-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256493
PNG
(US10329256, Example 38 | US9487512, 38 | US9944601...)
Show SMILES CC(C)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C17H26N2/c1-13(2)19-10-8-15(9-11-19)18-17-12-16(17)14-6-4-3-5-7-14/h3-7,13,15-18H,8-12H2,1-2H3/t16-,17+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256493
PNG
(US10329256, Example 38 | US9487512, 38 | US9944601...)
Show SMILES CC(C)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C17H26N2/c1-13(2)19-10-8-15(9-11-19)18-17-12-16(17)14-6-4-3-5-7-14/h3-7,13,15-18H,8-12H2,1-2H3/t16-,17+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256487
PNG
(US10329256, Example 32 | US9487512, 32 | US9944601...)
Show SMILES CS(=O)(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2O2S/c1-20(18,19)17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256485
PNG
(US10329256, Example 30 | US9487512, 30 | US9944601...)
Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C23H31N3O2S/c1-16(2)29(27,28)26-21-5-3-4-19(14-21)17-6-8-18(9-7-17)22-15-23(22)25-20-10-12-24-13-11-20/h3-9,14,16,20,22-26H,10-13,15H2,1-2H3/t22-,23+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256495
PNG
(US10329256, Example 40 | US9487512, 40 | US9944601...)
Show SMILES C1[C@H](NC2CCN(CC2)c2ccncc2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H23N3/c1-2-4-15(5-3-1)18-14-19(18)21-16-8-12-22(13-9-16)17-6-10-20-11-7-17/h1-7,10-11,16,18-19,21H,8-9,12-14H2/t18-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256481
PNG
(US10329256, Example 26 | US9487512, 26 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNC1
Show InChI InChI=1/C14H20N2/c1-2-4-12(5-3-1)13-8-14(13)16-10-11-6-7-15-9-11/h1-5,11,13-16H,6-10H2/t11?,13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50142189
PNG
(CHEMBL3759239 | US10329256, Example 5 | US9487512,...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccccc1)C1CCNCC1
Show InChI InChI=1/C15H22N2/c1-2-4-13(5-3-1)14-10-15(14)17-11-12-6-8-16-9-7-12/h1-5,12,14-17H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256463
PNG
(US10329256, Example 8 | US9487512, 8 | US9944601, ...)
Show SMILES C(CC1CCOCC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H23NO/c1-2-4-14(5-3-1)15-12-16(15)17-9-6-13-7-10-18-11-8-13/h1-5,13,15-17H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256469
PNG
(US10329256, Example 14 | US9487512, 14 | US9944601...)
Show SMILES C1[C@H](NC2CCC3(CCNCC3)CC2)[C@H]1c1ccccc1
Show InChI InChI=1/C19H28N2/c1-2-4-15(5-3-1)17-14-18(17)21-16-6-8-19(9-7-16)10-12-20-13-11-19/h1-5,16-18,20-21H,6-14H2/t17-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256474
PNG
(US10329256, Example 19 | US9487512, 19 | US9944601...)
Show SMILES Cc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2/c1-11-4-2-3-5-13(11)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256474
PNG
(US10329256, Example 19 | US9487512, 19 | US9944601...)
Show SMILES Cc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2/c1-11-4-2-3-5-13(11)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256485
PNG
(US10329256, Example 30 | US9487512, 30 | US9944601...)
Show SMILES CC(C)S(=O)(=O)Nc1cccc(c1)-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C23H31N3O2S/c1-16(2)29(27,28)26-21-5-3-4-19(14-21)17-6-8-18(9-7-17)22-15-23(22)25-20-10-12-24-13-11-20/h3-9,14,16,20,22-26H,10-13,15H2,1-2H3/t22-,23+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256458
PNG
(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256459
PNG
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)
Show SMILES C1[C@@H](NC2CCNCC2)[C@@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256465
PNG
(US10329256, Example 10 | US9487512, 10 | US9944601...)
Show SMILES C1[C@H](NC2CCCNC2)[C@H]1c1ccccc1
Show InChI InChI=1/C14H20N2/c1-2-5-11(6-3-1)13-9-14(13)16-12-7-4-8-15-10-12/h1-3,5-6,12-16H,4,7-10H2/t12?,13-,14+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256472
PNG
(US10329256, Example 17 | US9487512, 17 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cccnc1
Show InChI InChI=1/C13H19N3/c1-2-10(9-15-5-1)12-8-13(12)16-11-3-6-14-7-4-11/h1-2,5,9,11-14,16H,3-4,6-8H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256475
PNG
(US10329256, Example 20 | US9487512, 20 | US9944601...)
Show SMILES Fc1ccccc1C1CC1NC1CCNCC1
Show InChI InChI=1/C14H19FN2/c15-13-4-2-1-3-11(13)12-9-14(12)17-10-5-7-16-8-6-10/h1-4,10,12,14,16-17H,5-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256478
PNG
(US10329256, Example 23 | US9487512, 23 | US9944601...)
Show SMILES Oc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H20N2O/c17-12-3-1-10(2-4-12)13-9-14(13)16-11-5-7-15-8-6-11/h1-4,11,13-17H,5-9H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256492
PNG
(US10329256, Example 37 | US9487512, 37 | US9944601...)
Show SMILES CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C15H22N2/c1-17-9-7-13(8-10-17)16-15-11-14(15)12-5-3-2-4-6-12/h2-6,13-16H,7-11H2,1H3/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256494
PNG
(US10329256, Example 39 | US9487512, 39 | US9944601...)
Show SMILES FC(F)(F)CN1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1
Show InChI InChI=1/C16H21F3N2/c17-16(18,19)11-21-8-6-13(7-9-21)20-15-10-14(15)12-4-2-1-3-5-12/h1-5,13-15,20H,6-11H2/t14-,15+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256468
PNG
(US10329256, Example 13 | US9487512, 13 | US9944601...)
Show SMILES C1[C@H](NC2CC3CCC(C2)N3)[C@H]1c1ccccc1
Show InChI InChI=1/C16H22N2/c1-2-4-11(5-3-1)15-10-16(15)18-14-8-12-6-7-13(9-14)17-12/h1-5,12-18H,6-10H2/t12?,13?,14?,15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256471
PNG
(US10329256, Example 16 | US9487512, 16 | US9944601...)
Show SMILES C1[C@H](NC2CCNC3CCCCC23)[C@H]1c1ccccc1
Show InChI InChI=1/C18H26N2/c1-2-6-13(7-3-1)15-12-18(15)20-17-10-11-19-16-9-5-4-8-14(16)17/h1-3,6-7,14-20H,4-5,8-12H2/t14?,15-,16?,17?,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256472
PNG
(US10329256, Example 17 | US9487512, 17 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cccnc1
Show InChI InChI=1/C13H19N3/c1-2-10(9-15-5-1)12-8-13(12)16-11-3-6-14-7-4-11/h1-2,5,9,11-14,16H,3-4,6-8H2/t12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256473
PNG
(US10329256, Example 18 | US9487512, 18 | US9944601...)
Show SMILES C1[C@H](NC2CCNCC2)[C@H]1c1cncs1
Show InChI InChI=1/C11H17N3S/c1-3-12-4-2-8(1)14-10-5-9(10)11-6-13-7-15-11/h6-10,12,14H,1-5H2/t9-,10-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256480
PNG
(US10329256, Example 25 | US9487512, 25 | US9944601...)
Show SMILES CC1(CC1NC1CCNCC1)c1ccccc1
Show InChI InChI=1/C15H22N2/c1-15(12-5-3-2-4-6-12)11-14(15)17-13-7-9-16-10-8-13/h2-6,13-14,16-17H,7-11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256484
PNG
(US10329256, Example 29 | US9487512, 29 | US9944601...)
Show SMILES COc1ccc(NS(C)(=O)=O)cc1-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C22H29N3O3S/c1-28-22-8-7-18(25-29(2,26)27)13-20(22)16-5-3-15(4-6-16)19-14-21(19)24-17-9-11-23-12-10-17/h3-8,13,17,19,21,23-25H,9-12,14H2,1-2H3/t19-,21+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM256478
PNG
(US10329256, Example 23 | US9487512, 23 | US9944601...)
Show SMILES Oc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H20N2O/c17-12-3-1-10(2-4-12)13-9-14(13)16-11-5-7-15-8-6-11/h1-4,11,13-17H,5-9H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256488
PNG
(US10329256, Example 33 | US9487512, 33 | US9944601...)
Show SMILES CC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C16H21BrN2O/c1-11(20)19-8-6-14(7-9-19)18-16-10-15(16)12-2-4-13(17)5-3-12/h2-5,14-16,18H,6-10H2,1H3/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256479
PNG
(US10329256, Example 24 | US9487512, 24 | US9944601...)
Show SMILES C1C(NC2CCNCC2)C1c1ccc2ccccc2c1
Show InChI InChI=1/C18H22N2/c1-2-4-14-11-15(6-5-13(14)3-1)17-12-18(17)20-16-7-9-19-10-8-16/h1-6,11,16-20H,7-10,12H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256477
PNG
(US10329256, Example 22 | US9487512, 22 | US9944601...)
Show SMILES COc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2O/c1-18-13-4-2-11(3-5-13)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256476
PNG
(US10329256, Example 21 | US9487512, 21 | US9944601...)
Show SMILES Fc1ccc(cc1F)C1CC1NC1CCNCC1
Show InChI InChI=1/C14H18F2N2/c15-12-2-1-9(7-13(12)16)11-8-14(11)18-10-3-5-17-6-4-10/h1-2,7,10-11,14,17-18H,3-6,8H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256498
PNG
(US10329256, Example 43 | US9487512, 43 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1cccnc1)C1CCNCC1
Show InChI InChI=1/C20H25N3/c1-2-18(14-22-9-1)16-3-5-17(6-4-16)19-12-20(19)23-13-15-7-10-21-11-8-15/h1-6,9,14-15,19-21,23H,7-8,10-13H2/t19-,20+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256488
PNG
(US10329256, Example 33 | US9487512, 33 | US9944601...)
Show SMILES CC(=O)N1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(Br)cc1
Show InChI InChI=1/C16H21BrN2O/c1-11(20)19-8-6-14(7-9-19)18-16-10-15(16)12-2-4-13(17)5-3-12/h2-5,14-16,18H,6-10H2,1H3/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256477
PNG
(US10329256, Example 22 | US9487512, 22 | US9944601...)
Show SMILES COc1ccc(cc1)C1CC1NC1CCNCC1
Show InChI InChI=1/C15H22N2O/c1-18-13-4-2-11(3-5-13)14-10-15(14)17-12-6-8-16-9-7-12/h2-5,12,14-17H,6-10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256484
PNG
(US10329256, Example 29 | US9487512, 29 | US9944601...)
Show SMILES COc1ccc(NS(C)(=O)=O)cc1-c1ccc(cc1)[C@H]1C[C@@H]1NC1CCNCC1
Show InChI InChI=1/C22H29N3O3S/c1-28-22-8-7-18(25-29(2,26)27)13-20(22)16-5-3-15(4-6-16)19-14-21(19)24-17-9-11-23-12-10-17/h3-8,13,17,19,21,23-25H,9-12,14H2,1-2H3/t19-,21+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256497
PNG
(US10329256, Example 42 | US9487512, 42 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)C1CC1)C1CCNCC1
Show InChI InChI=1/C18H26N2/c1-2-14(1)15-3-5-16(6-4-15)17-11-18(17)20-12-13-7-9-19-10-8-13/h3-6,13-14,17-20H,1-2,7-12H2/t17-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256480
PNG
(US10329256, Example 25 | US9487512, 25 | US9944601...)
Show SMILES CC1(CC1NC1CCNCC1)c1ccccc1
Show InChI InChI=1/C15H22N2/c1-15(12-5-3-2-4-6-12)11-14(15)17-13-7-9-16-10-8-13/h2-6,13-14,16-17H,7-11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM256470
PNG
(US10329256, Example 15 | US9487512, 15 | US9944601...)
Show SMILES C1[C@H](NC2CC3(C2)CCNCC3)[C@H]1c1ccccc1
Show InChI InChI=1/C17H24N2/c1-2-4-13(5-3-1)15-10-16(15)19-14-11-17(12-14)6-8-18-9-7-17/h1-5,14-16,18-19H,6-12H2/t15-,16+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM256499
PNG
(US10329256, Example 44 | US9487512, 44 | US9944601...)
Show SMILES C(N[C@H]1C[C@@H]1c1ccc(cc1)-c1ccn[nH]1)C1CCNCC1
Show InChI InChI=1/C18H24N4/c1-3-15(17-7-10-21-22-17)4-2-14(1)16-11-18(16)20-12-13-5-8-19-9-6-13/h1-4,7,10,13,16,18-20H,5-6,8-9,11-12H2,(H,21,22)/t16-,18+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.78E+6n/an/an/an/an/an/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...


US Patent US10329256 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%