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Patent code US10335401

Compile Data Set for Download or QSAR
Found 95 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403547
PNG
(US10335401, No. I-57)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C26H25F8N3O6S/c1-44(40,41)14-21(38)36-13-19-18(20-8-7-17(12-35-20)43-23(27)28)11-24(26(32,33)34,37-22(19)39)15-3-5-16(6-4-15)42-10-2-9-25(29,30)31/h3-8,12,23H,2,9-11,13-14H2,1H3,(H,36,38)(H,37,39)/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.620n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403538
PNG
(US10335401, No. I-47)
Show SMILES CC(C)(O)c1ccc(nc1)C1=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H31F6N3O6S/c1-25(2,40)18-7-10-22(35-14-18)20-13-26(28(32,33)34,37-24(39)21(20)15-36-23(38)16-44(3,41)42)17-5-8-19(9-6-17)43-12-4-11-27(29,30)31/h5-10,14,40H,4,11-13,15-16H2,1-3H3,(H,36,38)(H,37,39)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.730n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403562
PNG
(US10335401, No. I-72)
Show SMILES CC(=C)c1ccc(nc1)C1=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H29F6N3O5S/c1-17(2)18-5-10-23(35-14-18)21-13-26(28(32,33)34,37-25(39)22(21)15-36-24(38)16-43(3,40)41)19-6-8-20(9-7-19)42-12-4-11-27(29,30)31/h5-10,14H,1,4,11-13,15-16H2,2-3H3,(H,36,38)(H,37,39)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403534
PNG
(US10335401, No. I-43)
Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H31F6N3O5S/c1-17(2)18-5-10-23(35-14-18)21-13-26(28(32,33)34,37-25(39)22(21)15-36-24(38)16-43(3,40)41)19-6-8-20(9-7-19)42-12-4-11-27(29,30)31/h5-10,14,17H,4,11-13,15-16H2,1-3H3,(H,36,38)(H,37,39)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403549
PNG
(US10335401, No. I-59)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C26H25F8N3O5S/c1-43(40,41)14-21(38)36-13-19-18(20-8-3-15(12-35-20)22(27)28)11-24(26(32,33)34,37-23(19)39)16-4-6-17(7-5-16)42-10-2-9-25(29,30)31/h3-8,12,22H,2,9-11,13-14H2,1H3,(H,36,38)(H,37,39)/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403570
PNG
(US10335401, No. I-86)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(CCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C25H23F8N3O4S/c1-41(39,40)13-20(37)35-12-18-17(19-7-4-15(11-34-19)21(26)27)10-23(25(31,32)33,36-22(18)38)16-5-2-14(3-6-16)8-9-24(28,29)30/h2-7,11,21H,8-10,12-13H2,1H3,(H,35,37)(H,36,38)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.90n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403519
PNG
(US10335401, No. I-27)
Show SMILES Cc1ccc(nc1)C1=C(CNC(=O)c2ccno2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H24F6N4O4/c1-16-3-8-21(34-14-16)19-13-25(27(31,32)33,17-4-6-18(7-5-17)40-12-2-10-26(28,29)30)37-23(38)20(19)15-35-24(39)22-9-11-36-41-22/h3-9,11,14H,2,10,12-13,15H2,1H3,(H,35,39)(H,37,38)/t25-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.20n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403518
PNG
(US10335401, No. I-26)
Show SMILES Cc1ccc(nc1)C1=C(CNC(=O)CC(F)(F)F)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H24F9N3O3/c1-15-3-8-20(36-13-15)18-11-23(26(33,34)35,38-22(40)19(18)14-37-21(39)12-25(30,31)32)16-4-6-17(7-5-16)41-10-2-9-24(27,28)29/h3-8,13H,2,9-12,14H2,1H3,(H,37,39)(H,38,40)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.30n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403506
PNG
(US10335401, No. I-12)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H27F6N3O6S/c1-40-18-8-9-21(33-13-18)19-12-24(26(30,31)32,35-23(37)20(19)14-34-22(36)15-42(2,38)39)16-4-6-17(7-5-16)41-11-3-10-25(27,28)29/h4-9,13H,3,10-12,14-15H2,1-2H3,(H,34,36)(H,35,37)/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.5n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403542
PNG
(US10335401, No. I-52)
Show SMILES CC(C)(O)c1ccc(nc1)C1=C(CNC(=O)C(C)(C)C#N)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C30H32F6N4O4/c1-26(2,17-37)25(42)39-16-22-21(23-11-8-19(15-38-23)27(3,4)43)14-28(30(34,35)36,40-24(22)41)18-6-9-20(10-7-18)44-13-5-12-29(31,32)33/h6-11,15,43H,5,12-14,16H2,1-4H3,(H,39,42)(H,40,41)/t28-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.10n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403539
PNG
(US10335401, No. I-48)
Show SMILES CC(C)(O)c1ccc(nc1)C1=C(CNC(=O)C2CS(=O)(=O)C2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C29H31F6N3O6S/c1-26(2,41)19-6-9-23(36-13-19)21-12-27(29(33,34)35,18-4-7-20(8-5-18)44-11-3-10-28(30,31)32)38-25(40)22(21)14-37-24(39)17-15-45(42,43)16-17/h4-9,13,17,41H,3,10-12,14-16H2,1-2H3,(H,37,39)(H,38,40)/t27-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.20n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403507
PNG
(US10335401, No. I-13)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)CC(F)(F)F)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H24F9N3O4/c1-41-17-7-8-20(36-13-17)18-11-23(26(33,34)35,38-22(40)19(18)14-37-21(39)12-25(30,31)32)15-3-5-16(6-4-15)42-10-2-9-24(27,28)29/h3-8,13H,2,9-12,14H2,1H3,(H,37,39)(H,38,40)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.30n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403588
PNG
(US10335401, No. I-112)
Show SMILES FC(F)c1ccc(nc1)C1=C(CNC(=O)CC(F)(F)F)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H22F11N3O3/c27-21(28)14-2-7-19(38-12-14)17-10-23(26(35,36)37,40-22(42)18(17)13-39-20(41)11-25(32,33)34)15-3-5-16(6-4-15)43-9-1-8-24(29,30)31/h2-7,12,21H,1,8-11,13H2,(H,39,41)(H,40,42)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.80n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403589
PNG
(US10335401, No. I-114)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C24H21F8N3O6S/c1-42(38,39)11-19(36)34-10-17-16(18-7-6-15(9-33-18)41-21(25)26)8-22(24(30,31)32,35-20(17)37)13-2-4-14(5-3-13)40-12-23(27,28)29/h2-7,9,21H,8,10-12H2,1H3,(H,34,36)(H,35,37)/t22-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.10n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403536
PNG
(US10335401, No. I-45)
Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(=O)C(C)(C)C#N)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C30H32F6N4O3/c1-18(2)19-6-11-24(38-15-19)22-14-28(30(34,35)36,40-25(41)23(22)16-39-26(42)27(3,4)17-37)20-7-9-21(10-8-20)43-13-5-12-29(31,32)33/h6-11,15,18H,5,12-14,16H2,1-4H3,(H,39,42)(H,40,41)/t28-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.40n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403504
PNG
(US10335401, No. I-10)
Show SMILES Cc1ccc(nc1)C1=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H27F6N3O5S/c1-16-4-9-21(33-13-16)19-12-24(26(30,31)32,35-23(37)20(19)14-34-22(36)15-41(2,38)39)17-5-7-18(8-6-17)40-11-3-10-25(27,28)29/h4-9,13H,3,10-12,14-15H2,1-2H3,(H,34,36)(H,35,37)/t24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<4.60n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403560
PNG
(US10335401, No. I-70)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(Br)cn1
Show InChI InChI=1S/C25H24BrF6N3O5S/c1-41(38,39)14-21(36)34-13-19-18(20-8-5-16(26)12-33-20)11-23(25(30,31)32,35-22(19)37)15-3-6-17(7-4-15)40-10-2-9-24(27,28)29/h3-8,12H,2,9-11,13-14H2,1H3,(H,34,36)(H,35,37)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.30n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403582
PNG
(US10335401, No. I-103)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cn1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C25H24F8N4O6S/c1-44(40,41)13-20(38)36-12-17-16(18-5-3-15(11-34-18)43-22(26)27)9-23(25(31,32)33,37-21(17)39)19-6-4-14(10-35-19)42-8-2-7-24(28,29)30/h3-6,10-11,22H,2,7-9,12-13H2,1H3,(H,36,38)(H,37,39)/t23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 6.60n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403573
PNG
(US10335401, No. I-91)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C24H21F8N3O5S/c1-41(38,39)11-19(36)34-10-17-16(18-7-2-13(9-33-18)20(25)26)8-22(24(30,31)32,35-21(17)37)14-3-5-15(6-4-14)40-12-23(27,28)29/h2-7,9,20H,8,10-12H2,1H3,(H,34,36)(H,35,37)/t22-/m0/s1
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n/an/a 6.80n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403511
PNG
(US10335401, No. I-17)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)c2ccno2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H24F6N4O5/c1-40-18-7-8-21(34-14-18)19-13-25(27(31,32)33,16-3-5-17(6-4-16)41-12-2-10-26(28,29)30)37-23(38)20(19)15-35-24(39)22-9-11-36-42-22/h3-9,11,14H,2,10,12-13,15H2,1H3,(H,35,39)(H,37,38)/t25-/m0/s1
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n/an/a 7.60n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403584
PNG
(US10335401, No. I-106)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)nc1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C25H24F8N4O6S/c1-44(40,41)13-19(38)35-12-17-16(18-5-4-15(11-34-18)43-22(26)27)9-23(25(31,32)33,37-21(17)39)14-3-6-20(36-10-14)42-8-2-7-24(28,29)30/h3-6,10-11,22H,2,7-9,12-13H2,1H3,(H,35,38)(H,37,39)/t23-/m0/s1
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n/an/a 7.70n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403508
PNG
(US10335401, No. I-14)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)C(C)C)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H29F6N3O4/c1-16(2)23(37)35-15-21-20(22-10-9-19(39-3)14-34-22)13-25(27(31,32)33,36-24(21)38)17-5-7-18(8-6-17)40-12-4-11-26(28,29)30/h5-10,14,16H,4,11-13,15H2,1-3H3,(H,35,37)(H,36,38)/t25-/m0/s1
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n/an/a 8n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403535
PNG
(US10335401, No. I-44)
Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(=O)C2CS(=O)(=O)C2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C29H31F6N3O5S/c1-17(2)18-4-9-24(36-13-18)22-12-27(29(33,34)35,20-5-7-21(8-6-20)43-11-3-10-28(30,31)32)38-26(40)23(22)14-37-25(39)19-15-44(41,42)16-19/h4-9,13,17,19H,3,10-12,14-16H2,1-2H3,(H,37,39)(H,38,40)/t27-/m0/s1
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n/an/a 9.20n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403583
PNG
(US10335401, No. I-105)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCC(F)F)cc1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C24H22F7N3O6S/c1-41(37,38)12-20(35)33-10-17-16(18-7-6-15(9-32-18)40-22(27)28)8-23(24(29,30)31,34-21(17)36)13-2-4-14(5-3-13)39-11-19(25)26/h2-7,9,19,22H,8,10-12H2,1H3,(H,33,35)(H,34,36)/t23-/m0/s1
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n/an/a 9.20n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403533
PNG
(US10335401, No. I-42)
Show SMILES CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(C)(C)O
Show InChI InChI=1S/C27H29F6N3O4/c1-16(37)34-15-21-20(22-10-7-18(14-35-22)24(2,3)39)13-25(27(31,32)33,36-23(21)38)17-5-8-19(9-6-17)40-12-4-11-26(28,29)30/h5-10,14,39H,4,11-13,15H2,1-3H3,(H,34,37)(H,36,38)/t25-/m0/s1
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n/an/a 10n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403509
PNG
(US10335401, No. I-15)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)C2CCC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H29F6N3O4/c1-40-20-10-11-23(35-15-20)21-14-26(28(32,33)34,37-25(39)22(21)16-36-24(38)17-4-2-5-17)18-6-8-19(9-7-18)41-13-3-12-27(29,30)31/h6-11,15,17H,2-5,12-14,16H2,1H3,(H,36,38)(H,37,39)/t26-/m0/s1
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n/an/a 10n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403543
PNG
(US10335401, No. I-53)
Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(=O)C2COC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C29H31F6N3O4/c1-17(2)18-4-9-24(36-13-18)22-12-27(29(33,34)35,38-26(40)23(22)14-37-25(39)19-15-41-16-19)20-5-7-21(8-6-20)42-11-3-10-28(30,31)32/h4-9,13,17,19H,3,10-12,14-16H2,1-2H3,(H,37,39)(H,38,40)/t27-/m0/s1
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n/an/a 11n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403522
PNG
(US10335401, No. I-30)
Show SMILES Cc1ccc(nc1)C1=C(CNC(=O)CC#N)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H24F6N4O3/c1-16-3-8-21(34-14-16)19-13-24(26(30,31)32,36-23(38)20(19)15-35-22(37)9-11-33)17-4-6-18(7-5-17)39-12-2-10-25(27,28)29/h3-8,14H,2,9-10,12-13,15H2,1H3,(H,35,37)(H,36,38)/t24-/m0/s1
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n/an/a 12n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403502
PNG
(US10335401, No. I-8)
Show SMILES Cc1ccc(nc1)C1=C(CNC(=O)C2CC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H27F6N3O3/c1-16-3-10-22(34-14-16)20-13-25(27(31,32)33,36-24(38)21(20)15-35-23(37)17-4-5-17)18-6-8-19(9-7-18)39-12-2-11-26(28,29)30/h3,6-10,14,17H,2,4-5,11-13,15H2,1H3,(H,35,37)(H,36,38)/t25-/m0/s1
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n/an/a 13n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403554
PNG
(US10335401, No. I-64)
Show SMILES CC(C)(C)OC(=O)N1CC(C1)C(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C32H34F8N4O5/c1-29(2,3)49-28(47)44-16-19(17-44)26(45)42-15-23-22(24-10-5-18(14-41-24)25(33)34)13-30(32(38,39)40,43-27(23)46)20-6-8-21(9-7-20)48-12-4-11-31(35,36)37/h5-10,14,19,25H,4,11-13,15-17H2,1-3H3,(H,42,45)(H,43,46)/t30-/m0/s1
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n/an/a 14n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403529
PNG
(US10335401, No. I-38)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)C(C)(C)C#N)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H28F6N4O4/c1-25(2,16-35)24(40)37-15-21-20(22-10-9-19(41-3)14-36-22)13-26(28(32,33)34,38-23(21)39)17-5-7-18(8-6-17)42-12-4-11-27(29,30)31/h5-10,14H,4,11-13,15H2,1-3H3,(H,37,40)(H,38,39)/t26-/m0/s1
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n/an/a 17n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403575
PNG
(US10335401, No. I-95)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(cc1)C1CC1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C25H24F5N3O5S/c1-39(36,37)13-21(34)32-12-19-18(20-9-8-17(11-31-20)38-23(26)27)10-24(25(28,29)30,33-22(19)35)16-6-4-15(5-7-16)14-2-3-14/h4-9,11,14,23H,2-3,10,12-13H2,1H3,(H,32,34)(H,33,35)/t24-/m0/s1
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n/an/a 17n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403546
PNG
(US10335401, No. I-56)
Show SMILES CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C25H23F8N3O4/c1-14(37)34-13-19-18(20-8-7-17(12-35-20)40-22(26)27)11-23(25(31,32)33,36-21(19)38)15-3-5-16(6-4-15)39-10-2-9-24(28,29)30/h3-8,12,22H,2,9-11,13H2,1H3,(H,34,37)(H,36,38)/t23-/m0/s1
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n/an/a 17n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403526
PNG
(US10335401, No. I-35)
Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(C)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H29F6N3O3/c1-16(2)18-5-10-23(35-14-18)21-13-25(27(31,32)33,36-24(38)22(21)15-34-17(3)37)19-6-8-20(9-7-19)39-12-4-11-26(28,29)30/h5-10,14,16H,4,11-13,15H2,1-3H3,(H,34,37)(H,36,38)/t25-/m0/s1
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n/an/a 18n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403521
PNG
(US10335401, No. I-29)
Show SMILES Cc1ccc(nc1)C1=C(CNC(=O)C2CS(=O)(=O)C2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H27F6N3O5S/c1-16-3-8-22(34-12-16)20-11-25(27(31,32)33,18-4-6-19(7-5-18)41-10-2-9-26(28,29)30)36-24(38)21(20)13-35-23(37)17-14-42(39,40)15-17/h3-8,12,17H,2,9-11,13-15H2,1H3,(H,35,37)(H,36,38)/t25-/m0/s1
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n/an/a 18n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403496
PNG
(US10335401, No. I-1)
Show SMILES Cc1ccc(cc1)C1=C(CNS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H26F6N2O4S/c1-16-4-6-17(7-5-16)20-14-23(25(29,30)31,33-22(34)21(20)15-32-38(2,35)36)18-8-10-19(11-9-18)37-13-3-12-24(26,27)28/h4-11,32H,3,12-15H2,1-2H3,(H,33,34)/t23-/m0/s1
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n/an/a 21n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403571
PNG
(US10335401, No. I-88)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(cc1)C1CC1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C25H24F5N3O4S/c1-38(36,37)13-21(34)32-12-19-18(20-9-6-16(11-31-20)22(26)27)10-24(25(28,29)30,33-23(19)35)17-7-4-15(5-8-17)14-2-3-14/h4-9,11,14,22H,2-3,10,12-13H2,1H3,(H,32,34)(H,33,35)/t24-/m0/s1
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n/an/a 21n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403581
PNG
(US10335401, No. I-102)
Show SMILES COC\C=C\c1ccc(cc1)[C@@]1(CC(=C(CNC(=O)CS(C)(=O)=O)C(=O)N1)c1ccc(OC(F)F)cn1)C(F)(F)F
Show InChI InChI=1S/C26H26F5N3O6S/c1-39-11-3-4-16-5-7-17(8-6-16)25(26(29,30)31)12-19(21-10-9-18(13-32-21)40-24(27)28)20(23(36)34-25)14-33-22(35)15-41(2,37)38/h3-10,13,24H,11-12,14-15H2,1-2H3,(H,33,35)(H,34,36)/b4-3+/t25-/m0/s1
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n/an/a 21n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403568
PNG
(US10335401, No. I-83 | US10335401, No. I-85)
Show SMILES CC(C(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F)S(C)(=O)=O
Show InChI InChI=1S/C27H27F8N3O5S/c1-15(44(2,41)42)23(39)37-14-20-19(21-9-4-16(13-36-21)22(28)29)12-25(27(33,34)35,38-24(20)40)17-5-7-18(8-6-17)43-11-3-10-26(30,31)32/h4-9,13,15,22H,3,10-12,14H2,1-2H3,(H,37,39)(H,38,40)/t15?,25-/m0/s1
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n/an/a 22n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403568
PNG
(US10335401, No. I-83 | US10335401, No. I-85)
Show SMILES CC(C(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F)S(C)(=O)=O
Show InChI InChI=1S/C27H27F8N3O5S/c1-15(44(2,41)42)23(39)37-14-20-19(21-9-4-16(13-36-21)22(28)29)12-25(27(33,34)35,38-24(20)40)17-5-7-18(8-6-17)43-11-3-10-26(30,31)32/h4-9,13,15,22H,3,10-12,14H2,1-2H3,(H,37,39)(H,38,40)/t15?,25-/m0/s1
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n/an/a 24n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403565
PNG
(US10335401, No. I-78)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(Br)cc1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C22H19BrF5N3O5S/c1-37(34,35)11-18(32)30-10-16-15(17-7-6-14(9-29-17)36-20(24)25)8-21(22(26,27)28,31-19(16)33)12-2-4-13(23)5-3-12/h2-7,9,20H,8,10-11H2,1H3,(H,30,32)(H,31,33)/t21-/m0/s1
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n/an/a 25n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403578
PNG
(US10335401, No. I-99)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(cc1)-c1ccccc1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C28H24F5N3O5S/c1-42(39,40)16-24(37)35-15-22-21(23-12-11-20(14-34-23)41-26(29)30)13-27(28(31,32)33,36-25(22)38)19-9-7-18(8-10-19)17-5-3-2-4-6-17/h2-12,14,26H,13,15-16H2,1H3,(H,35,37)(H,36,38)/t27-/m0/s1
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n/an/a 26n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403550
PNG
(US10335401, No. I-60)
Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(=O)CO)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H29F6N3O4/c1-16(2)17-4-9-22(34-13-17)20-12-25(27(31,32)33,36-24(39)21(20)14-35-23(38)15-37)18-5-7-19(8-6-18)40-11-3-10-26(28,29)30/h4-9,13,16,37H,3,10-12,14-15H2,1-2H3,(H,35,38)(H,36,39)/t25-/m0/s1
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n/an/a 27n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403551
PNG
(US10335401, No. I-61)
Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(=O)CN(C)C)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C29H34F6N4O3/c1-18(2)19-6-11-24(36-15-19)22-14-27(29(33,34)35,38-26(41)23(22)16-37-25(40)17-39(3)4)20-7-9-21(10-8-20)42-13-5-12-28(30,31)32/h6-11,15,18H,5,12-14,16-17H2,1-4H3,(H,37,40)(H,38,41)/t27-/m0/s1
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n/an/a 27n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403572
PNG
(US10335401, No. I-90)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C23H19F8N3O5S/c1-40(37,38)11-18(35)33-10-16-15(17-7-2-12(9-32-17)19(24)25)8-21(22(26,27)28,34-20(16)36)13-3-5-14(6-4-13)39-23(29,30)31/h2-7,9,19H,8,10-11H2,1H3,(H,33,35)(H,34,36)/t21-/m0/s1
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n/an/a 27n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403528
PNG
(US10335401, No. I-37)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)CC#N)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H24F6N4O4/c1-39-18-7-8-21(34-14-18)19-13-24(26(30,31)32,36-23(38)20(19)15-35-22(37)9-11-33)16-3-5-17(6-4-16)40-12-2-10-25(27,28)29/h3-8,14H,2,9-10,12-13,15H2,1H3,(H,35,37)(H,36,38)/t24-/m0/s1
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n/an/a 28n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403503
PNG
(US10335401, No. I-9)
Show SMILES CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(CO)cn1
Show InChI InChI=1S/C25H25F6N3O4/c1-15(36)32-13-20-19(21-8-3-16(14-35)12-33-21)11-23(25(29,30)31,34-22(20)37)17-4-6-18(7-5-17)38-10-2-9-24(26,27)28/h3-8,12,35H,2,9-11,13-14H2,1H3,(H,32,36)(H,34,37)/t23-/m0/s1
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n/an/a 29n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403498
PNG
(US10335401, No. I-4)
Show SMILES CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(C)cn1
Show InChI InChI=1S/C25H25F6N3O3/c1-15-4-9-21(33-13-15)19-12-23(25(29,30)31,34-22(36)20(19)14-32-16(2)35)17-5-7-18(8-6-17)37-11-3-10-24(26,27)28/h4-9,13H,3,10-12,14H2,1-2H3,(H,32,35)(H,34,36)/t23-/m0/s1
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n/an/a 32n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403587
PNG
(US10335401, No. I-111)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(CC(NC1=O)(c1ccc(Br)cc1F)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C22H18BrF6N3O4S/c1-37(35,36)10-18(33)31-9-14-13(17-5-2-11(8-30-17)19(25)26)7-21(22(27,28)29,32-20(14)34)15-4-3-12(23)6-16(15)24/h2-6,8,19H,7,9-10H2,1H3,(H,31,33)(H,32,34)
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SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403548
PNG
(US10335401, No. I-58)
Show SMILES CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C25H23F8N3O3/c1-14(37)34-13-19-18(20-8-3-15(12-35-20)21(26)27)11-23(25(31,32)33,36-22(19)38)16-4-6-17(7-5-16)39-10-2-9-24(28,29)30/h3-8,12,21H,2,9-11,13H2,1H3,(H,34,37)(H,36,38)/t23-/m0/s1
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SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403514
PNG
(US10335401, No. I-20)
Show SMILES COc1ccc(nc1)C1=C(CNS(=O)(=O)CC#N)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H24F6N4O5S/c1-39-18-7-8-21(33-14-18)19-13-23(25(29,30)31,35-22(36)20(19)15-34-41(37,38)12-10-32)16-3-5-17(6-4-16)40-11-2-9-24(26,27)28/h3-8,14,34H,2,9,11-13,15H2,1H3,(H,35,36)/t23-/m0/s1
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n/an/a 35n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403576
PNG
(US10335401, No. I-97)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(CN2CCOCC2)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C27H29F5N4O5S/c1-42(39,40)16-23(37)34-14-21-20(22-7-4-18(13-33-22)24(28)29)12-26(27(30,31)32,35-25(21)38)19-5-2-17(3-6-19)15-36-8-10-41-11-9-36/h2-7,13,24H,8-12,14-16H2,1H3,(H,34,37)(H,35,38)/t26-/m0/s1
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SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403557
PNG
(US10335401, No. I-67)
Show SMILES FC(F)c1ccc(nc1)C1=C(CNC(=O)C2(F)CNC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H25F9N4O3/c28-21(29)15-2-7-20(38-11-15)18-10-25(27(34,35)36,16-3-5-17(6-4-16)43-9-1-8-26(31,32)33)40-22(41)19(18)12-39-23(42)24(30)13-37-14-24/h2-7,11,21,37H,1,8-10,12-14H2,(H,39,42)(H,40,41)/t25-/m0/s1
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SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403517
PNG
(US10335401, No. I-24)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)C2CC(=O)C2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H27F6N3O5/c1-41-20-7-8-23(35-14-20)21-13-26(28(32,33)34,17-3-5-19(6-4-17)42-10-2-9-27(29,30)31)37-25(40)22(21)15-36-24(39)16-11-18(38)12-16/h3-8,14,16H,2,9-13,15H2,1H3,(H,36,39)(H,37,40)/t26-/m0/s1
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SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403580
PNG
(US10335401, No. I-101)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(cc1)C1=CCOCC1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C27H26F5N3O6S/c1-42(38,39)15-23(36)34-14-21-20(22-7-6-19(13-33-22)41-25(28)29)12-26(27(30,31)32,35-24(21)37)18-4-2-16(3-5-18)17-8-10-40-11-9-17/h2-8,13,25H,9-12,14-15H2,1H3,(H,34,36)(H,35,37)/t26-/m0/s1
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n/an/a 42n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403559
PNG
(US10335401, No. I-69)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ncc(s1)C1CC1
Show InChI InChI=1S/C26H27F6N3O5S2/c1-42(38,39)14-21(36)33-12-19-18(23-34-13-20(41-23)15-3-4-15)11-24(26(30,31)32,35-22(19)37)16-5-7-17(8-6-16)40-10-2-9-25(27,28)29/h5-8,13,15H,2-4,9-12,14H2,1H3,(H,33,36)(H,35,37)/t24-/m0/s1
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n/an/a 43n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403531
PNG
(US10335401, No. I-40)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)CO)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H25F6N3O5/c1-38-17-7-8-20(32-12-17)18-11-23(25(29,30)31,34-22(37)19(18)13-33-21(36)14-35)15-3-5-16(6-4-15)39-10-2-9-24(26,27)28/h3-8,12,35H,2,9-11,13-14H2,1H3,(H,33,36)(H,34,37)/t23-/m0/s1
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n/an/a 43n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403585
PNG
(US10335401, No. I-108)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(cc1)C(F)(F)F)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C23H19F8N3O5S/c1-40(37,38)11-18(35)33-10-16-15(17-7-6-14(9-32-17)39-20(24)25)8-21(23(29,30)31,34-19(16)36)12-2-4-13(5-3-12)22(26,27)28/h2-7,9,20H,8,10-11H2,1H3,(H,33,35)(H,34,36)/t21-/m0/s1
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n/an/a 46n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403510
PNG
(US10335401, No. I-16)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)CC(C)(C)C)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C29H33F6N3O4/c1-26(2,3)15-24(39)37-17-22-21(23-11-10-20(41-4)16-36-23)14-27(29(33,34)35,38-25(22)40)18-6-8-19(9-7-18)42-13-5-12-28(30,31)32/h6-11,16H,5,12-15,17H2,1-4H3,(H,37,39)(H,38,40)/t27-/m0/s1
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n/an/a 52n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403527
PNG
(US10335401, No. I-36)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)C2COC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H27F6N3O5/c1-39-19-7-8-22(34-12-19)20-11-25(27(31,32)33,36-24(38)21(20)13-35-23(37)16-14-40-15-16)17-3-5-18(6-4-17)41-10-2-9-26(28,29)30/h3-8,12,16H,2,9-11,13-15H2,1H3,(H,35,37)(H,36,38)/t25-/m0/s1
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n/an/a 53n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403552
PNG
(US10335401, No. I-62)
Show SMILES OCC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OC(F)F)cn1
Show InChI InChI=1S/C25H23F8N3O5/c26-22(27)41-16-6-7-19(34-11-16)17-10-23(25(31,32)33,36-21(39)18(17)12-35-20(38)13-37)14-2-4-15(5-3-14)40-9-1-8-24(28,29)30/h2-7,11,22,37H,1,8-10,12-13H2,(H,35,38)(H,36,39)/t23-/m0/s1
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n/an/a 59n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403574
PNG
(US10335401, No. I-94)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(Br)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C22H19BrF5N3O4S/c1-36(34,35)11-18(32)30-10-16-15(17-7-2-12(9-29-17)19(24)25)8-21(22(26,27)28,31-20(16)33)13-3-5-14(23)6-4-13/h2-7,9,19H,8,10-11H2,1H3,(H,30,32)(H,31,33)/t21-/m0/s1
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n/an/a 59n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403537
PNG
(US10335401, No. I-46)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)C2CS(=O)(=O)C2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H27F6N3O6S/c1-41-19-7-8-22(34-12-19)20-11-25(27(31,32)33,17-3-5-18(6-4-17)42-10-2-9-26(28,29)30)36-24(38)21(20)13-35-23(37)16-14-43(39,40)15-16/h3-8,12,16H,2,9-11,13-15H2,1H3,(H,35,37)(H,36,38)/t25-/m0/s1
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n/an/a 62n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403577
PNG
(US10335401, No. I-98)
Show SMILES Cn1cc(cn1)-c1ccc(cc1)[C@@]1(CC(=C(CNC(=O)CS(C)(=O)=O)C(=O)N1)c1ccc(OC(F)F)cn1)C(F)(F)F
Show InChI InChI=1S/C26H24F5N5O5S/c1-36-13-16(10-34-36)15-3-5-17(6-4-15)25(26(29,30)31)9-19(21-8-7-18(11-32-21)41-24(27)28)20(23(38)35-25)12-33-22(37)14-42(2,39)40/h3-8,10-11,13,24H,9,12,14H2,1-2H3,(H,33,37)(H,35,38)/t25-/m0/s1
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n/an/a 70n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403523
PNG
(US10335401, No. I-31)
Show SMILES Cc1ccc(nc1)C1=C(CNC(=O)CO)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H25F6N3O4/c1-15-3-8-20(32-12-15)18-11-23(25(29,30)31,34-22(37)19(18)13-33-21(36)14-35)16-4-6-17(7-5-16)38-10-2-9-24(26,27)28/h3-8,12,35H,2,9-11,13-14H2,1H3,(H,33,36)(H,34,37)/t23-/m0/s1
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n/an/a 70n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403532
PNG
(US10335401, No. I-41)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)C(C)(C)O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H29F6N3O5/c1-24(2,39)23(38)35-15-20-19(21-10-9-18(40-3)14-34-21)13-25(27(31,32)33,36-22(20)37)16-5-7-17(8-6-16)41-12-4-11-26(28,29)30/h5-10,14,39H,4,11-13,15H2,1-3H3,(H,35,38)(H,36,37)/t25-/m0/s1
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n/an/a 75n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403563
PNG
(US10335401, No. I-73)
Show SMILES CC(=C)c1ccc(nc1)C1=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H29F6N3O5S/c1-17(2)18-5-10-23(35-14-18)21-13-26(28(32,33)34,37-25(39)22(21)15-36-24(38)16-43(3,40)41)19-6-8-20(9-7-19)42-12-4-11-27(29,30)31/h5-10,14H,1,4,11-13,15-16H2,2-3H3,(H,36,38)(H,37,39)/t26-/m1/s1
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n/an/a 77n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403564
PNG
(US10335401, No. I-75)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(cc1)C(F)(F)F)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C23H19F8N3O4S/c1-39(37,38)11-18(35)33-10-16-15(17-7-2-12(9-32-17)19(24)25)8-21(23(29,30)31,34-20(16)36)13-3-5-14(6-4-13)22(26,27)28/h2-7,9,19H,8,10-11H2,1H3,(H,33,35)(H,34,36)/t21-/m0/s1
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n/an/a 78n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403544
PNG
(US10335401, No. I-54)
Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(=O)CC(=O)OC(C)(C)C)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C32H37F6N3O5/c1-19(2)20-7-12-25(39-17-20)23-16-30(32(36,37)38,21-8-10-22(11-9-21)45-14-6-13-31(33,34)35)41-28(44)24(23)18-40-26(42)15-27(43)46-29(3,4)5/h7-12,17,19H,6,13-16,18H2,1-5H3,(H,40,42)(H,41,44)/t30-/m0/s1
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n/an/a 82n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403586
PNG
(US10335401, No. I-110)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(CC(NC1=O)(c1cnn(CCCC(F)(F)F)c1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C23H23F8N5O4S/c1-41(39,40)12-18(37)33-10-16-15(17-4-3-13(8-32-17)19(24)25)7-21(23(29,30)31,35-20(16)38)14-9-34-36(11-14)6-2-5-22(26,27)28/h3-4,8-9,11,19H,2,5-7,10,12H2,1H3,(H,33,37)(H,35,38)
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n/an/a 91n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403530
PNG
(US10335401, No. I-39)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)C2(CC2)C#N)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H26F6N4O4/c1-41-19-7-8-22(36-14-19)20-13-26(28(32,33)34,17-3-5-18(6-4-17)42-12-2-9-27(29,30)31)38-23(39)21(20)15-37-24(40)25(16-35)10-11-25/h3-8,14H,2,9-13,15H2,1H3,(H,37,40)(H,38,39)/t26-/m0/s1
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n/an/a 91n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403524
PNG
(US10335401, No. I-32)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)NC(C)C)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H30F6N4O4/c1-16(2)36-24(39)35-15-21-20(22-10-9-19(40-3)14-34-22)13-25(27(31,32)33,37-23(21)38)17-5-7-18(8-6-17)41-12-4-11-26(28,29)30/h5-10,14,16H,4,11-13,15H2,1-3H3,(H,37,38)(H2,35,36,39)/t25-/m0/s1
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n/an/a 97n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403520
PNG
(US10335401, No. I-28)
Show SMILES Cc1ccc(nc1)C1=C(CNS(=O)(=O)CC#N)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H24F6N4O4S/c1-16-3-8-21(33-14-16)19-13-23(25(29,30)31,35-22(36)20(19)15-34-40(37,38)12-10-32)17-4-6-18(7-5-17)39-11-2-9-24(26,27)28/h3-8,14,34H,2,9,11-13,15H2,1H3,(H,35,36)/t23-/m0/s1
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n/an/a 100n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403505
PNG
(US10335401, No. I-11)
Show SMILES COc1ccc(nc1)C1=C(CNC(C)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H25F6N3O4/c1-15(35)32-14-20-19(21-9-8-18(37-2)13-33-21)12-23(25(29,30)31,34-22(20)36)16-4-6-17(7-5-16)38-11-3-10-24(26,27)28/h4-9,13H,3,10-12,14H2,1-2H3,(H,32,35)(H,34,36)/t23-/m0/s1
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n/an/a 110n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403590
PNG
(US10335401, No. I-115)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccccc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C22H20F5N3O4S/c1-35(33,34)12-18(31)29-11-16-15(17-8-7-13(10-28-17)19(23)24)9-21(22(25,26)27,30-20(16)32)14-5-3-2-4-6-14/h2-8,10,19H,9,11-12H2,1H3,(H,29,31)(H,30,32)/t21-/m0/s1
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n/an/a 110n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403553
PNG
(US10335401, No. I-63)
Show SMILES OCC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C25H23F8N3O4/c26-21(27)14-2-7-19(34-11-14)17-10-23(25(31,32)33,36-22(39)18(17)12-35-20(38)13-37)15-3-5-16(6-4-15)40-9-1-8-24(28,29)30/h2-7,11,21,37H,1,8-10,12-13H2,(H,35,38)(H,36,39)/t23-/m0/s1
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n/an/a 110n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403500
PNG
(US10335401, No. I-6)
Show SMILES Cc1ccc(nc1)C1=C(CNC(N)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H24F6N4O3/c1-14-3-8-19(32-12-14)17-11-22(24(28,29)30,34-20(35)18(17)13-33-21(31)36)15-4-6-16(7-5-15)37-10-2-9-23(25,26)27/h3-8,12H,2,9-11,13H2,1H3,(H,34,35)(H3,31,33,36)/t22-/m0/s1
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n/an/a 120n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403497
PNG
(US10335401, No. I-3)
Show SMILES Cc1ccc(nc1)C1=C(CNS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H25F6N3O4S/c1-15-4-9-20(31-13-15)18-12-22(24(28,29)30,33-21(34)19(18)14-32-38(2,35)36)16-5-7-17(8-6-16)37-11-3-10-23(25,26)27/h4-9,13,32H,3,10-12,14H2,1-2H3,(H,33,34)/t22-/m0/s1
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n/an/a 120n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403541
PNG
(US10335401, No. I-51)
Show SMILES CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(C)=O
Show InChI InChI=1S/C26H25F6N3O4/c1-15(36)17-4-9-22(34-13-17)20-12-24(26(30,31)32,35-23(38)21(20)14-33-16(2)37)18-5-7-19(8-6-18)39-11-3-10-25(27,28)29/h4-9,13H,3,10-12,14H2,1-2H3,(H,33,37)(H,35,38)/t24-/m0/s1
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n/an/a 130n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

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Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403567
PNG
(US10335401, No. I-81)
Show SMILES CS(=O)(=O)C1(CC1)C(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C28H27F8N3O5S/c1-45(42,43)25(10-11-25)24(41)38-15-20-19(21-8-3-16(14-37-21)22(29)30)13-26(28(34,35)36,39-23(20)40)17-4-6-18(7-5-17)44-12-2-9-27(31,32)33/h3-8,14,22H,2,9-13,15H2,1H3,(H,38,41)(H,39,40)/t26-/m0/s1
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n/an/a 140n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403540
PNG
(US10335401, No. I-49)
Show SMILES CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(Br)cn1
Show InChI InChI=1S/C24H22BrF6N3O3/c1-14(35)32-13-19-18(20-8-5-16(25)12-33-20)11-22(24(29,30)31,34-21(19)36)15-3-6-17(7-4-15)37-10-2-9-23(26,27)28/h3-8,12H,2,9-11,13H2,1H3,(H,32,35)(H,34,36)/t22-/m0/s1
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n/an/a 140n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403501
PNG
(US10335401, No. I-7)
Show SMILES COC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(C)cn1
Show InChI InChI=1S/C25H25F6N3O4/c1-15-4-9-20(32-13-15)18-12-23(25(29,30)31,34-21(35)19(18)14-33-22(36)37-2)16-5-7-17(8-6-16)38-11-3-10-24(26,27)28/h4-9,13H,3,10-12,14H2,1-2H3,(H,33,36)(H,34,35)/t23-/m0/s1
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n/an/a 150n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403545
PNG
(US10335401, No. I-55)
Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(=O)CC(O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H29F6N3O5/c1-16(2)17-4-9-22(35-14-17)20-13-26(28(32,33)34,37-25(41)21(20)15-36-23(38)12-24(39)40)18-5-7-19(8-6-18)42-11-3-10-27(29,30)31/h4-9,14,16H,3,10-13,15H2,1-2H3,(H,36,38)(H,37,41)(H,39,40)/t26-/m0/s1
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n/an/a 160n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403515
PNG
(US10335401, No. I-22)
Show SMILES COc1ccc(nc1)C1=C(CNS(=O)(=O)C2CCOCC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H31F6N3O6S/c1-41-20-7-8-24(35-16-20)22-15-26(28(32,33)34,18-3-5-19(6-4-18)43-12-2-11-27(29,30)31)37-25(38)23(22)17-36-44(39,40)21-9-13-42-14-10-21/h3-8,16,21,36H,2,9-15,17H2,1H3,(H,37,38)/t26-/m0/s1
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n/an/a 200n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403499
PNG
(US10335401, No. I-5)
Show SMILES Cc1ccc(nc1)C1=C(CNS(N)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C23H24F6N4O4S/c1-14-3-8-19(31-12-14)17-11-21(23(27,28)29,33-20(34)18(17)13-32-38(30,35)36)15-4-6-16(7-5-15)37-10-2-9-22(24,25)26/h3-8,12,32H,2,9-11,13H2,1H3,(H,33,34)(H2,30,35,36)/t21-/m0/s1
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n/an/a 230n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403513
PNG
(US10335401, No. I-19)
Show SMILES COc1ccc(nc1)C1=C(CNS(=O)(=O)CC(F)(F)F)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H24F9N3O5S/c1-41-17-7-8-20(35-12-17)18-11-22(25(32,33)34,15-3-5-16(6-4-15)42-10-2-9-23(26,27)28)37-21(38)19(18)13-36-43(39,40)14-24(29,30)31/h3-8,12,36H,2,9-11,13-14H2,1H3,(H,37,38)/t22-/m0/s1
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n/an/a 240n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403555
PNG
(US10335401, No. I-65)
Show SMILES FC(F)c1ccc(nc1)C1=C(CNC(=O)C2CNC2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H26F8N4O3/c28-22(29)15-2-7-21(37-13-15)19-10-25(27(33,34)35,39-24(41)20(19)14-38-23(40)16-11-36-12-16)17-3-5-18(6-4-17)42-9-1-8-26(30,31)32/h2-7,13,16,22,36H,1,8-12,14H2,(H,38,40)(H,39,41)/t25-/m0/s1
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n/an/a 280n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403512
PNG
(US10335401, No. I-18)
Show SMILES COc1ccc(nc1)C1=C(CNS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H25F6N3O5S/c1-37-17-8-9-20(31-13-17)18-12-22(24(28,29)30,33-21(34)19(18)14-32-39(2,35)36)15-4-6-16(7-5-15)38-11-3-10-23(25,26)27/h4-9,13,32H,3,10-12,14H2,1-2H3,(H,33,34)/t22-/m0/s1
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n/an/a 330n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403525
PNG
(US10335401, No. I-33)
Show SMILES COc1ccc(nc1)C1=C(CNC(=O)OC(C)C)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H29F6N3O5/c1-16(2)41-24(38)35-15-21-20(22-10-9-19(39-3)14-34-22)13-25(27(31,32)33,36-23(21)37)17-5-7-18(8-6-17)40-12-4-11-26(28,29)30/h5-10,14,16H,4,11-13,15H2,1-3H3,(H,35,38)(H,36,37)/t25-/m0/s1
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n/an/a 340n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403579
PNG
(US10335401, No. I-100)
Show SMILES Cn1ccc(cc1=O)-c1ccc(cc1)[C@@]1(CC(=C(CNC(=O)CS(C)(=O)=O)C(=O)N1)c1ccc(OC(F)F)cn1)C(F)(F)F
Show InChI InChI=1S/C28H25F5N4O6S/c1-37-10-9-17(11-24(37)39)16-3-5-18(6-4-16)27(28(31,32)33)12-20(22-8-7-19(13-34-22)43-26(29)30)21(25(40)36-27)14-35-23(38)15-44(2,41)42/h3-11,13,26H,12,14-15H2,1-2H3,(H,35,38)(H,36,40)/t27-/m0/s1
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SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403556
PNG
(US10335401, No. I-66)
Show SMILES CC1(CNC1)C(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F
Show InChI InChI=1S/C28H28F8N4O3/c1-25(14-37-15-25)24(42)39-13-20-19(21-8-3-16(12-38-21)22(29)30)11-26(28(34,35)36,40-23(20)41)17-4-6-18(7-5-17)43-10-2-9-27(31,32)33/h3-8,12,22,37H,2,9-11,13-15H2,1H3,(H,39,42)(H,40,41)/t26-/m0/s1
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SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403558
PNG
(US10335401, No. I-68)
Show SMILES CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ncc(s1)C1CC1
Show InChI InChI=1S/C25H25F6N3O3S/c1-14(35)32-12-19-18(22-33-13-20(38-22)15-3-4-15)11-23(25(29,30)31,34-21(19)36)16-5-7-17(8-6-16)37-10-2-9-24(26,27)28/h5-8,13,15H,2-4,9-12H2,1H3,(H,32,35)(H,34,36)/t23-/m0/s1
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US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403516
PNG
(US10335401, No. I-23)
Show SMILES COc1ccc(nc1)C1=C(CNS(=O)(=O)c2ccccc2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C29H27F6N3O5S/c1-42-21-12-13-25(36-17-21)23-16-27(29(33,34)35,19-8-10-20(11-9-19)43-15-5-14-28(30,31)32)38-26(39)24(23)18-37-44(40,41)22-6-3-2-4-7-22/h2-4,6-13,17,37H,5,14-16,18H2,1H3,(H,38,39)/t27-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 750n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403561
PNG
(US10335401, No. I-71)
Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(Br)cn1
Show InChI InChI=1S/C25H24BrF6N3O5S/c1-41(38,39)14-21(36)34-13-19-18(20-8-5-16(26)12-33-20)11-23(25(30,31)32,35-22(19)37)15-3-6-17(7-4-15)40-10-2-9-24(27,28)29/h3-8,12H,2,9-11,13-14H2,1H3,(H,34,36)(H,35,37)/t23-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 940n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM403566
PNG
(US10335401, No. I-80)
Show SMILES CC(C)(C(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F)S(C)(=O)=O
Show InChI InChI=1S/C28H29F8N3O5S/c1-25(2,45(3,42)43)24(41)38-15-20-19(21-10-5-16(14-37-21)22(29)30)13-26(28(34,35)36,39-23(20)40)17-6-8-18(9-7-17)44-12-4-11-27(31,32)33/h5-10,14,22H,4,11-13,15H2,1-3H3,(H,38,41)(H,39,40)/t26-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 990n/an/an/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...


US Patent US10335401 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%