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Patent code US10336684

Compile Data Set for Download or QSAR
Found 60 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403684
PNG
(2-(4-((1S,3R)-3-Phenoxycyclohexyl)phenethoxy)aceti...)
Show SMILES OC(=O)COCCc1ccc(cc1)[C@H]1CCC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C22H26O4/c23-22(24)16-25-14-13-17-9-11-18(12-10-17)19-5-4-8-21(15-19)26-20-6-2-1-3-7-20/h1-3,6-7,9-12,19,21H,4-5,8,13-16H2,(H,23,24)/t19-,21+/m0/s1
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n/an/an/an/a 1.03E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403738
PNG
(US10336684, Example 62)
Show SMILES OC(=O)[C@@H]1C[C@H]1CCc1ccc(cc1)N1CCCC(CC1)Oc1ccccc1
Show InChI InChI=1S/C24H29NO3/c26-24(27)23-17-19(23)11-8-18-9-12-20(13-10-18)25-15-4-7-22(14-16-25)28-21-5-2-1-3-6-21/h1-3,5-6,9-10,12-13,19,22-23H,4,7-8,11,14-17H2,(H,26,27)/t19-,22?,23-/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403698
PNG
(2-(4-(3-Phenoxycyclopentyl)phenethoxy)acetic acid ...)
Show SMILES OC(=O)COCCc1ccc(cc1)C1CCC(C1)Oc1ccccc1
Show InChI InChI=1S/C21H24O4/c22-21(23)15-24-13-12-16-6-8-17(9-7-16)18-10-11-20(14-18)25-19-4-2-1-3-5-19/h1-9,18,20H,10-15H2,(H,22,23)
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403702
PNG
((S)-5-(4-(3-Phenoxypiperidin-1-yl)phenyl)pentanoic...)
Show SMILES OC(=O)CCCCc1ccc(cc1)N1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C22H27NO3/c24-22(25)11-5-4-7-18-12-14-19(15-13-18)23-16-6-10-21(17-23)26-20-8-2-1-3-9-20/h1-3,8-9,12-15,21H,4-7,10-11,16-17H2,(H,24,25)/t21-/m0/s1
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US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403714
PNG
(US10336684, Example 38)
Show SMILES OC(=O)COCCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C22H25ClO4/c23-19-8-10-20(11-9-19)27-21-3-1-2-18(14-21)17-6-4-16(5-7-17)12-13-26-15-22(24)25/h4-11,18,21H,1-3,12-15H2,(H,24,25)/t18-,21+/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403736
PNG
(US10336684, Example 60)
Show SMILES OC(=O)CCCCc1ccc(cc1)N1CC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C21H25NO3/c23-21(24)9-5-4-6-17-10-12-18(13-11-17)22-15-14-20(16-22)25-19-7-2-1-3-8-19/h1-3,7-8,10-13,20H,4-6,9,14-16H2,(H,23,24)/t20-/m0/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403681
PNG
(5-(4-((+/−)-3-Phenoxycyclohexyl)phenyl)penta...)
Show SMILES OC(=O)CCCCc1ccc(cc1)[C@@H]1CCC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C23H28O3/c24-23(25)12-5-4-7-18-13-15-19(16-14-18)20-8-6-11-22(17-20)26-21-9-2-1-3-10-21/h1-3,9-10,13-16,20,22H,4-8,11-12,17H2,(H,24,25)/t20-,22-/m1/s1
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n/an/an/an/a 2.36E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403686
PNG
((1S,2S)-2-(4-((+/−)-3-Phenoxycyclohexyl)phen...)
Show SMILES OC(=O)[C@H]1C[C@@H]1CCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C24H28O3/c25-24(26)23-16-20(23)14-11-17-9-12-18(13-10-17)19-5-4-8-22(15-19)27-21-6-2-1-3-7-21/h1-3,6-7,9-10,12-13,19-20,22-23H,4-5,8,11,14-16H2,(H,25,26)/t19-,20+,22+,23+/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403689
PNG
((1R,2R)-2-(4-((+/−)-3-Phenoxycyclohexyl)phen...)
Show SMILES OC(=O)[C@@H]1C[C@H]1CCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C24H28O3/c25-24(26)23-16-20(23)14-11-17-9-12-18(13-10-17)19-5-4-8-22(15-19)27-21-6-2-1-3-7-21/h1-3,6-7,9-10,12-13,19-20,22-23H,4-5,8,11,14-16H2,(H,25,26)/t19-,20-,22+,23-/m1/s1
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US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403693
PNG
(2-(4-(3-Phenoxycycloheptyl)phenethoxy)acetic acid ...)
Show SMILES OC(=O)COCCc1ccc(cc1)C1CCCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C23H28O4/c24-23(25)17-26-15-14-18-10-12-19(13-11-18)20-6-4-5-9-22(16-20)27-21-7-2-1-3-8-21/h1-3,7-8,10-13,20,22H,4-6,9,14-17H2,(H,24,25)
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US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403700
PNG
(2-(4-(3-Phenoxypiperidin-1-yl)phenethoxy)acetic ac...)
Show SMILES OC(=O)COCCc1ccc(cc1)N1CCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C21H25NO4/c23-21(24)16-25-14-12-17-8-10-18(11-9-17)22-13-4-7-20(15-22)26-19-5-2-1-3-6-19/h1-3,5-6,8-11,20H,4,7,12-16H2,(H,23,24)
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US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403701
PNG
((R)-5-(4-(3-Phenoxypiperidin-1-yl)phenyl)pentanoic...)
Show SMILES OC(=O)CCCCc1ccc(cc1)N1CCC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C22H27NO3/c24-22(25)11-5-4-7-18-12-14-19(15-13-18)23-16-6-10-21(17-23)26-20-8-2-1-3-9-20/h1-3,8-9,12-15,21H,4-7,10-11,16-17H2,(H,24,25)/t21-/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403706
PNG
(2-(3-(4-(3-Phenoxypiperidin-1-yl)phenyl)propoxy)ac...)
Show SMILES OC(=O)COCCCc1ccc(cc1)N1CCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C22H27NO4/c24-22(25)17-26-15-5-6-18-10-12-19(13-11-18)23-14-4-9-21(16-23)27-20-7-2-1-3-8-20/h1-3,7-8,10-13,21H,4-6,9,14-17H2,(H,24,25)
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403710
PNG
(US10336684, Example 34)
Show SMILES Cc1ccc(O[C@H]2CCC[C@H](C2)c2ccc(CCOCC(O)=O)cc2)cc1F
Show InChI InChI=1S/C23H27FO4/c1-16-5-10-21(14-22(16)24)28-20-4-2-3-19(13-20)18-8-6-17(7-9-18)11-12-27-15-23(25)26/h5-10,14,19-20H,2-4,11-13,15H2,1H3,(H,25,26)/t19-,20+/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403716
PNG
(US10336684, Example 40)
Show SMILES OC(=O)[C@H]1C[C@@H]1CCc1ccc(cc1)[C@@H]1CCC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C24H28O3/c25-24(26)23-16-20(23)14-11-17-9-12-18(13-10-17)19-5-4-8-22(15-19)27-21-6-2-1-3-7-21/h1-3,6-7,9-10,12-13,19-20,22-23H,4-5,8,11,14-16H2,(H,25,26)/t19-,20+,22-,23+/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403720
PNG
(US10336684, Example 44)
Show SMILES OC(=O)CCCCc1ccc(cc1)C1CCCCC(C1)Oc1ccc(Cl)cc1
Show InChI InChI=1S/C24H29ClO3/c25-21-13-15-22(16-14-21)28-23-7-3-2-6-20(17-23)19-11-9-18(10-12-19)5-1-4-8-24(26)27/h9-16,20,23H,1-8,17H2,(H,26,27)
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403697
PNG
(5-(4-(3-Phenoxycyclopentyl)phenyl)pentanoic acid (...)
Show SMILES OC(=O)CCCCc1ccc(cc1)C1CCC(C1)Oc1ccccc1
Show InChI InChI=1S/C22H26O3/c23-22(24)9-5-4-6-17-10-12-18(13-11-17)19-14-15-21(16-19)25-20-7-2-1-3-8-20/h1-3,7-8,10-13,19,21H,4-6,9,14-16H2,(H,23,24)
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US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403708
PNG
(5-(4-(3-(4-Fluorophenoxy)azepan-1-yl)phenyl)pentan...)
Show SMILES OC(=O)CCCCc1ccc(cc1)N1CCCCC(C1)Oc1ccc(F)cc1
Show InChI InChI=1S/C23H28FNO3/c24-19-10-14-21(15-11-19)28-22-6-3-4-16-25(17-22)20-12-8-18(9-13-20)5-1-2-7-23(26)27/h8-15,22H,1-7,16-17H2,(H,26,27)
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US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403711
PNG
(US10336684, Example 35)
Show SMILES Cc1ccc(O[C@H]2CCC[C@H](C2)c2ccc(CCOCC(O)=O)cc2)cn1
Show InChI InChI=1S/C22H27NO4/c1-16-5-10-21(14-23-16)27-20-4-2-3-19(13-20)18-8-6-17(7-9-18)11-12-26-15-22(24)25/h5-10,14,19-20H,2-4,11-13,15H2,1H3,(H,24,25)/t19-,20+/m1/s1
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n/an/an/an/a 1.61E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403719
PNG
(US10336684, Example 43)
Show SMILES CC(C)O[C@H]1CCC[C@H](C1)c1ccc(OC[C@H]2C[C@@H]2C(O)=O)cc1
Show InChI InChI=1S/C20H28O4/c1-13(2)24-18-5-3-4-15(10-18)14-6-8-17(9-7-14)23-12-16-11-19(16)20(21)22/h6-9,13,15-16,18-19H,3-5,10-12H2,1-2H3,(H,21,22)/t15-,16-,18+,19+/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403727
PNG
(US10336684, Example 51)
Show SMILES OC(=O)[C@@H]1C[C@H]1CCc1ccc(cc1)N1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C23H27NO3/c25-23(26)22-15-18(22)11-8-17-9-12-19(13-10-17)24-14-4-7-21(16-24)27-20-5-2-1-3-6-20/h1-3,5-6,9-10,12-13,18,21-22H,4,7-8,11,14-16H2,(H,25,26)/t18-,21+,22-/m1/s1
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n/an/an/an/a 1.90E+3n/an/an/an/a



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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403735
PNG
(US10336684, Example 59)
Show SMILES OC(=O)COCCc1ccc(cc1)N1CCC(C1)Oc1ccccc1
Show InChI InChI=1S/C20H23NO4/c22-20(23)15-24-13-11-16-6-8-17(9-7-16)21-12-10-19(14-21)25-18-4-2-1-3-5-18/h1-9,19H,10-15H2,(H,22,23)
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n/an/an/an/a 5.27E+3n/an/an/an/a



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US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403686
PNG
((1S,2S)-2-(4-((+/−)-3-Phenoxycyclohexyl)phen...)
Show SMILES OC(=O)[C@H]1C[C@@H]1CCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C24H28O3/c25-24(26)23-16-20(23)14-11-17-9-12-18(13-10-17)19-5-4-8-22(15-19)27-21-6-2-1-3-7-21/h1-3,6-7,9-10,12-13,19-20,22-23H,4-5,8,11,14-16H2,(H,25,26)/t19-,20+,22+,23+/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403693
PNG
(2-(4-(3-Phenoxycycloheptyl)phenethoxy)acetic acid ...)
Show SMILES OC(=O)COCCc1ccc(cc1)C1CCCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C23H28O4/c24-23(25)17-26-15-14-18-10-12-19(13-11-18)20-6-4-5-9-22(16-20)27-21-7-2-1-3-8-21/h1-3,7-8,10-13,20,22H,4-6,9,14-17H2,(H,24,25)
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403705
PNG
((S)-5-(2-Fluoro-4-(3-phenoxypiperidin-1-yl)phenyl)...)
Show SMILES OC(=O)CCCCc1ccc(cc1F)N1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C22H26FNO3/c23-21-15-18(13-12-17(21)7-4-5-11-22(25)26)24-14-6-10-20(16-24)27-19-8-2-1-3-9-19/h1-3,8-9,12-13,15,20H,4-7,10-11,14,16H2,(H,25,26)/t20-/m0/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403722
PNG
(US10336684, Example 46)
Show SMILES OC(=O)CCCCc1ccc(cc1)C1CCCCC(C1)Oc1ccccc1Cl
Show InChI InChI=1S/C24H29ClO3/c25-22-10-4-5-11-23(22)28-21-9-3-2-8-20(17-21)19-15-13-18(14-16-19)7-1-6-12-24(26)27/h4-5,10-11,13-16,20-21H,1-3,6-9,12,17H2,(H,26,27)
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403726
PNG
(US10336684, Example 50)
Show SMILES OC(=O)[C@@H]1C[C@H]1CCc1ccc(cc1)N1CCC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C23H27NO3/c25-23(26)22-15-18(22)11-8-17-9-12-19(13-10-17)24-14-4-7-21(16-24)27-20-5-2-1-3-6-20/h1-3,5-6,9-10,12-13,18,21-22H,4,7-8,11,14-16H2,(H,25,26)/t18-,21-,22-/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403728
PNG
(US10336684, Example 52)
Show SMILES OC(=O)[C@@H]1C[C@H]1CCc1ccc(cc1)N1CCC[C@@H](C1)Oc1ccc(F)cc1
Show InChI InChI=1S/C23H26FNO3/c24-18-7-11-20(12-8-18)28-21-2-1-13-25(15-21)19-9-4-16(5-10-19)3-6-17-14-22(17)23(26)27/h4-5,7-12,17,21-22H,1-3,6,13-15H2,(H,26,27)/t17-,21+,22-/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403730
PNG
(US10336684, Example 54)
Show SMILES OC(=O)[C@H]1C[C@@H]1CCc1ccc(cc1)N1CCC[C@@H](C1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c25-23(26)22-15-19(22)11-8-17-9-12-21(13-10-17)24-14-4-7-20(16-24)18-5-2-1-3-6-18/h1-3,5-6,9-10,12-13,19-20,22H,4,7-8,11,14-16H2,(H,25,26)/t19-,20-,22-/m0/s1
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Bristol=Myers Squibb Company

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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403731
PNG
(US10336684, Example 55)
Show SMILES OC(=O)[C@@H]1C[C@H]1CCc1ccc(cc1)N1CCC[C@H](C1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c25-23(26)22-15-19(22)11-8-17-9-12-21(13-10-17)24-14-4-7-20(16-24)18-5-2-1-3-6-18/h1-3,5-6,9-10,12-13,19-20,22H,4,7-8,11,14-16H2,(H,25,26)/t19-,20-,22-/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403699
PNG
(5-(4-(3-Phenoxypiperidin-1-yl)phenyl)pentanoic aci...)
Show SMILES OC(=O)CCCCc1ccc(cc1)N1CCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C22H27NO3/c24-22(25)11-5-4-7-18-12-14-19(15-13-18)23-16-6-10-21(17-23)26-20-8-2-1-3-9-20/h1-3,8-9,12-15,21H,4-7,10-11,16-17H2,(H,24,25)
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403721
PNG
(US10336684, Example 45)
Show SMILES OC(=O)CCCCc1ccc(cc1)C1CCCCC(C1)Oc1cccc(Cl)c1
Show InChI InChI=1S/C24H29ClO3/c25-21-8-5-10-23(17-21)28-22-9-3-2-7-20(16-22)19-14-12-18(13-15-19)6-1-4-11-24(26)27/h5,8,10,12-15,17,20,22H,1-4,6-7,9,11,16H2,(H,26,27)
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403723
PNG
(US10336684, Example 47)
Show SMILES CC(C)OC1CCC(C1)c1ccc(CCCCC(O)=O)cc1
Show InChI InChI=1S/C19H28O3/c1-14(2)22-18-12-11-17(13-18)16-9-7-15(8-10-16)5-3-4-6-19(20)21/h7-10,14,17-18H,3-6,11-13H2,1-2H3,(H,20,21)
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403732
PNG
(US10336684, Example 56)
Show SMILES OC(=O)[C@@H]1C[C@H]1CCc1ccc(cc1)N1CCC[C@@H](C1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c25-23(26)22-15-19(22)11-8-17-9-12-21(13-10-17)24-14-4-7-20(16-24)18-5-2-1-3-6-18/h1-3,5-6,9-10,12-13,19-20,22H,4,7-8,11,14-16H2,(H,25,26)/t19-,20+,22-/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403739
PNG
(US10336684, Example 63)
Show SMILES OC(=O)COCCc1ccc(cc1)N1CC(C1)Oc1ccccc1
Show InChI InChI=1S/C19H21NO4/c21-19(22)14-23-11-10-15-6-8-16(9-7-15)20-12-18(13-20)24-17-4-2-1-3-5-17/h1-9,18H,10-14H2,(H,21,22)
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403680
PNG
(5-(4-((+/−)-3-Phenoxycyclohexyl)phenyl)penta...)
Show SMILES OC(=O)CCCCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C23H28O3/c24-23(25)12-5-4-7-18-13-15-19(16-14-18)20-8-6-11-22(17-20)26-21-9-2-1-3-10-21/h1-3,9-10,13-16,20,22H,4-8,11-12,17H2,(H,24,25)/t20-,22+/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403682
PNG
(5-(4-((+/−)-3-Isopropoxycyclohexyl)phenyl)pe...)
Show SMILES CC(C)O[C@H]1CCC[C@H](C1)c1ccc(CCCCC(O)=O)cc1
Show InChI InChI=1S/C20H30O3/c1-15(2)23-19-8-5-7-18(14-19)17-12-10-16(11-13-17)6-3-4-9-20(21)22/h10-13,15,18-19H,3-9,14H2,1-2H3,(H,21,22)/t18-,19+/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403683
PNG
(2-(4-((+/−)-3-Phenoxycyclohexyl)phenethoxy)a...)
Show SMILES OC(=O)COCCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C22H26O4/c23-22(24)16-25-14-13-17-9-11-18(12-10-17)19-5-4-8-21(15-19)26-20-6-2-1-3-7-20/h1-3,6-7,9-12,19,21H,4-5,8,13-16H2,(H,23,24)/t19-,21+/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403704
PNG
((S)-5-(2,6-Difluoro-4-(3-phenoxypiperidin-1-yl)phe...)
Show SMILES OC(=O)CCCCc1c(F)cc(cc1F)N1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C22H25F2NO3/c23-20-13-16(14-21(24)19(20)10-4-5-11-22(26)27)25-12-6-9-18(15-25)28-17-7-2-1-3-8-17/h1-3,7-8,13-14,18H,4-6,9-12,15H2,(H,26,27)/t18-/m0/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403707
PNG
((+/−)-2-((4-(3-Phenoxypiperidin-1-yl)phenoxy...)
Show SMILES OC(=O)[C@@H]1C[C@@H]1COc1ccc(cc1)N1CCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C22H25NO4/c24-22(25)21-13-16(21)15-26-18-10-8-17(9-11-18)23-12-4-7-20(14-23)27-19-5-2-1-3-6-19/h1-3,5-6,8-11,16,20-21H,4,7,12-15H2,(H,24,25)/t16-,20?,21-/m1/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403724
PNG
(US10336684, Example 48)
Show SMILES OC(=O)[C@H]1C[C@@H]1CCc1ccc(cc1)N1CCC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C23H27NO3/c25-23(26)22-15-18(22)11-8-17-9-12-19(13-10-17)24-14-4-7-21(16-24)27-20-5-2-1-3-6-20/h1-3,5-6,9-10,12-13,18,21-22H,4,7-8,11,14-16H2,(H,25,26)/t18-,21+,22-/m0/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403734
PNG
(US10336684, Example 58)
Show SMILES OC(=O)CCCCc1ccc(cc1)N1CCC(CC1)Oc1ccccc1
Show InChI InChI=1S/C22H27NO3/c24-22(25)9-5-4-6-18-10-12-19(13-11-18)23-16-14-21(15-17-23)26-20-7-2-1-3-8-20/h1-3,7-8,10-13,21H,4-6,9,14-17H2,(H,24,25)
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403687
PNG
((1S,2S)-2-(4-((1S,3S)-3-Phenoxycyclohexyl)phenethy...)
Show SMILES OC(=O)[C@H]1C[C@@H]1CCc1ccc(cc1)[C@H]1CCC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C24H28O3/c25-24(26)23-16-20(23)14-11-17-9-12-18(13-10-17)19-5-4-8-22(15-19)27-21-6-2-1-3-7-21/h1-3,6-7,9-10,12-13,19-20,22-23H,4-5,8,11,14-16H2,(H,25,26)/t19-,20-,22+,23-/m0/s1
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403691
PNG
(5-(4-(3-Phenoxycycloheptyl)phenyl)pentanoic acid (...)
Show SMILES OC(=O)CCCCc1ccc(cc1)C1CCCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C24H30O3/c25-24(26)13-7-4-8-19-14-16-20(17-15-19)21-9-5-6-12-23(18-21)27-22-10-2-1-3-11-22/h1-3,10-11,14-17,21,23H,4-9,12-13,18H2,(H,25,26)
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Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403693
PNG
(2-(4-(3-Phenoxycycloheptyl)phenethoxy)acetic acid ...)
Show SMILES OC(=O)COCCc1ccc(cc1)C1CCCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C23H28O4/c24-23(25)17-26-15-14-18-10-12-19(13-11-18)20-6-4-5-9-22(16-20)27-21-7-2-1-3-8-21/h1-3,7-8,10-13,20,22H,4-6,9,14-17H2,(H,24,25)
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n/an/an/an/a 1.99E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403715
PNG
(US10336684, Example 39)
Show SMILES OC(=O)COCCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccc(cc1)C#N
Show InChI InChI=1S/C23H25NO4/c24-15-18-6-10-21(11-7-18)28-22-3-1-2-20(14-22)19-8-4-17(5-9-19)12-13-27-16-23(25)26/h4-11,20,22H,1-3,12-14,16H2,(H,25,26)/t20-,22+/m1/s1
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n/an/an/an/a 3.24E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403717
PNG
(US10336684, Example 41)
Show SMILES OC(=O)[C@@H]1C[C@H]1CCc1ccc(cc1)[C@@H]1CCC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C24H28O3/c25-24(26)23-16-20(23)14-11-17-9-12-18(13-10-17)19-5-4-8-22(15-19)27-21-6-2-1-3-7-21/h1-3,6-7,9-10,12-13,19-20,22-23H,4-5,8,11,14-16H2,(H,25,26)/t19-,20-,22-,23-/m1/s1
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n/an/an/an/a 1.94E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403718
PNG
(US10336684, Example 42)
Show SMILES OC(=O)[C@H]1C[C@@H]1COc1ccc(cc1)[C@@H]1CCC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C23H26O4/c24-23(25)22-14-18(22)15-26-19-11-9-16(10-12-19)17-5-4-8-21(13-17)27-20-6-2-1-3-7-20/h1-3,6-7,9-12,17-18,21-22H,4-5,8,13-15H2,(H,24,25)/t17-,18-,21-,22+/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403729
PNG
(US10336684, Example 53)
Show SMILES OC(=O)[C@H]1C[C@@H]1CCc1ccc(cc1)N1CCC[C@H](C1)c1ccccc1
Show InChI InChI=1S/C23H27NO2/c25-23(26)22-15-19(22)11-8-17-9-12-21(13-10-17)24-14-4-7-20(16-24)18-5-2-1-3-6-18/h1-3,5-6,9-10,12-13,19-20,22H,4,7-8,11,14-16H2,(H,25,26)/t19-,20+,22-/m0/s1
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n/an/an/an/a 3.61E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403733
PNG
(US10336684, Example 57)
Show SMILES OC(=O)COCCc1ccc(cc1)N1CCCC(C1)c1ccccc1
Show InChI InChI=1S/C21H25NO3/c23-21(24)16-25-14-12-17-8-10-20(11-9-17)22-13-4-7-19(15-22)18-5-2-1-3-6-18/h1-3,5-6,8-11,19H,4,7,12-16H2,(H,23,24)
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n/an/an/an/a 2.26E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403737
PNG
(US10336684, Example 61)
Show SMILES OC(=O)CCCCc1ccc(cc1)N1CC[C@H](C1)Oc1ccccc1
Show InChI InChI=1S/C21H25NO3/c23-21(24)9-5-4-6-17-10-12-18(13-11-17)22-15-14-20(16-22)25-19-7-2-1-3-8-19/h1-3,7-8,10-13,20H,4-6,9,14-16H2,(H,23,24)/t20-/m1/s1
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n/an/an/an/a 3.38E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403683
PNG
(2-(4-((+/−)-3-Phenoxycyclohexyl)phenethoxy)a...)
Show SMILES OC(=O)COCCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C22H26O4/c23-22(24)16-25-14-13-17-9-11-18(12-10-17)19-5-4-8-21(15-19)26-20-6-2-1-3-7-20/h1-3,6-7,9-12,19,21H,4-5,8,13-16H2,(H,23,24)/t19-,21+/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403686
PNG
((1S,2S)-2-(4-((+/−)-3-Phenoxycyclohexyl)phen...)
Show SMILES OC(=O)[C@H]1C[C@@H]1CCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C24H28O3/c25-24(26)23-16-20(23)14-11-17-9-12-18(13-10-17)19-5-4-8-22(15-19)27-21-6-2-1-3-7-21/h1-3,6-7,9-10,12-13,19-20,22-23H,4-5,8,11,14-16H2,(H,25,26)/t19-,20+,22+,23+/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403693
PNG
(2-(4-(3-Phenoxycycloheptyl)phenethoxy)acetic acid ...)
Show SMILES OC(=O)COCCc1ccc(cc1)C1CCCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C23H28O4/c24-23(25)17-26-15-14-18-10-12-19(13-11-18)20-6-4-5-9-22(16-20)27-21-7-2-1-3-8-21/h1-3,7-8,10-13,20,22H,4-6,9,14-17H2,(H,24,25)
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403703
PNG
((S)-5-(4-(3-(4-Fluorophenoxy)piperidin-1-yl)phenyl...)
Show SMILES OC(=O)CCCCc1ccc(cc1)N1CCC[C@@H](C1)Oc1ccc(F)cc1
Show InChI InChI=1S/C22H26FNO3/c23-18-9-13-20(14-10-18)27-21-5-3-15-24(16-21)19-11-7-17(8-12-19)4-1-2-6-22(25)26/h7-14,21H,1-6,15-16H2,(H,25,26)/t21-/m0/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403709
PNG
(US10336684, Example 32)
Show SMILES OC(=O)CCCCc1ccc(cc1)C1CCCC(C1)Nc1ccccc1
Show InChI InChI=1S/C23H29NO2/c25-23(26)12-5-4-7-18-13-15-19(16-14-18)20-8-6-11-22(17-20)24-21-9-2-1-3-10-21/h1-3,9-10,13-16,20,22,24H,4-8,11-12,17H2,(H,25,26)
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403712
PNG
(US10336684, Example 36)
Show SMILES Cc1ccc(O[C@H]2CCC[C@H](C2)c2ccc(CCOCC(O)=O)cc2)cc1
Show InChI InChI=1S/C23H28O4/c1-17-5-11-21(12-6-17)27-22-4-2-3-20(15-22)19-9-7-18(8-10-19)13-14-26-16-23(24)25/h5-12,20,22H,2-4,13-16H2,1H3,(H,24,25)/t20-,22+/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403713
PNG
(US10336684, Example 37)
Show SMILES OC(=O)COCCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccc(F)cc1
Show InChI InChI=1S/C22H25FO4/c23-19-8-10-20(11-9-19)27-21-3-1-2-18(14-21)17-6-4-16(5-7-17)12-13-26-15-22(24)25/h4-11,18,21H,1-3,12-15H2,(H,24,25)/t18-,21+/m1/s1
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403725
PNG
(US10336684, Example 49)
Show SMILES OC(=O)[C@H]1C[C@@H]1CCc1ccc(cc1)N1CCC[C@@H](C1)Oc1ccccc1
Show InChI InChI=1S/C23H27NO3/c25-23(26)22-15-18(22)11-8-17-9-12-19(13-10-17)24-14-4-7-21(16-24)27-20-5-2-1-3-6-20/h1-3,5-6,9-10,12-13,18,21-22H,4,7-8,11,14-16H2,(H,25,26)/t18-,21-,22-/m0/s1
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n/an/an/an/a 1.31E+3n/an/an/an/a



Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
G-protein coupled receptor 120


(Homo sapiens (Human))
BDBM403691
PNG
(5-(4-(3-Phenoxycycloheptyl)phenyl)pentanoic acid (...)
Show SMILES OC(=O)CCCCc1ccc(cc1)C1CCCCC(C1)Oc1ccccc1
Show InChI InChI=1S/C24H30O3/c25-24(26)13-7-4-8-19-14-16-20(17-15-19)21-9-5-6-12-23(18-21)27-22-10-2-1-3-11-22/h1-3,10-11,14-17,21,23H,4-9,12-13,18H2,(H,25,26)
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Bristol=Myers Squibb Company

US Patent


Assay Description
The human and mouse GPR120-mediated intracellular phosphorylated ERK assays were also established using CHO-K1 cells stably transfected with the shor...


US Patent US10336684 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%