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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406681 (1-(4-(7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406684 (1-(4-(7-(4-(pyridin-2-oxy)phenyl)-1H-pyrazazo[3,4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406686 (1-(4-(7-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406685 (1-(4-(7-(4-(pyridin-2-oxy)phenyl)-1H-pyrazolo[3,4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406672 ((E)-4-(dimethylamino)-1-(3-(7-(4-phenoxyphenyl)-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406695 (US10336755, Example 22b) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406674 (1-(3-(7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406680 (N-(3-(7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406682 (N-(1-(7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406673 (7-(4-phenoxyphenyl)-5-(1-(ethenylsulfonyl)piperidi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406690 (4-(5-(1-acryloylpyrrolidin-3-yl)-1H-pyrazolo[3,4-c...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406671 (1-(3-(7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406687 (1-(4-(7-(4-(3-fluorophenoxyl)phenyl)-1H-pyrazolo[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406694 (US10336755, Example 22a) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406692 (1-(3-(7-(4-phenoxyphenyl)-1H-indazol-5-yl)piperidi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406693 (1-(2-(7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406675 (1-(4-(7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406683 (1-(3-((7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyrid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406691 (4-(5-(1-(but-2-ynoyl)pyrrolidin-3-yl)-1H-pyrazolo[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406670 (1-(3-(7-(4-(oxetan-3-oxy)phenyl)-1H-pyrazolo[3,4-c...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406689 (1-(3-(7-(4-phenoxyphenyl)-1H-pyrazolo[3,4-c]pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406669 (1-(3-(7-(4-(morpholinomethyl)phenyl)-1H-pyrazolo[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM406688 (1-(4-(7-(4-(pyrrolidin-1-ylmethyl)phenyl)-1H-pyraz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing Innocare Pharma Tech Co., Ltd. US Patent | Assay Description In vitro activity of BTK is measured by detecting ADP produced in a kinase reaction with an ADP-Glo™ kinase assay kit from Promega Company. In the ki... | US Patent US10336755 (2019) BindingDB Entry DOI: 10.7270/Q20G3NH5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
