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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408335 (N-(1-(2-chlorophenyl)cyclopropyl)-5-(5-(difluorome...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408339 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408288 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408345 (N-(1-(2-chloro-4-fluorophenyl)cyclopropyl)-5-(5-(d...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408287 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408359 (N-(1-(5-chloro-2-fluorophenyl)cyclopropyl)-5-(5-(d...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408340 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408334 (N-(1-(3-chlorophenyl)cyclopropyl)-5-(5-(difluorome...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408320 (US10357493, Example 38(+)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408332 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408388 (N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408380 (US10357493, Example 98) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408390 (US10357493, Example 106) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408400 (N-(2-(4-(difluoromethoxy)-2-fluorophenyl)-2-((5-(5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408356 (N-(1-(3-chloro-2-fluorophenyl)cyclopropyl)-5-(5-(d...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408398 (N-(2-(4-(difluoromethoxy)phenyl)-2-((5-(5-(difluor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408431 (N-(2-(4-(difluoromethoxy)-2-fluorophenyl)-2-((5-(5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408432 (N-(2-(4-(difluoromethoxy)-2-fluorophenyl)-2-((5-(5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408357 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408437 (N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408338 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408342 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408396 (US10357493, Example 113) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408376 (US10357493, Example 91) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408300 (US10357493, Example 20(+)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408385 (US10357493, Example 101(+)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408344 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408337 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408343 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408434 (N-(2-(4-(difluoromethoxy)-2-fluorophenyl)-2-((5-(5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408365 (US10357493, Example 80) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408336 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408281 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408329 (5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-N-(1-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408469 (N-(2-(4-chlorophenyl)-2-((5-(5-(difluoromethyl)-1,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408410 (N-(3-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408391 (N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408330 (N-(1-(4-bromophenyl)cyclopropyl)-5-(5-(difluoromet...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408393 (N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408360 (N-(1-(2-chloro-3-methylphenyl)cyclopropyl)-5-(5-(d...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408371 (US10357493, Example 86) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408347 (N-(1-(6-bromopyridin-3-yl)cyclopropyl)-5-(5-(diflu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408381 (US10357493, Example 99-R) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408319 (N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408403 (N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408373 (US10357493, Example 88) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408314 (N-(1-(4-(difluoromethoxy)-2-fluorophenyl)cycloprop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408459 (N-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408383 (US10357493, Example 100(+)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM408333 (N-(1-(4-chlorophenyl)cyclopropyl)-5-(5-(difluorome...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Selenity Therapeutics (Bermuda), Ltd. US Patent | Assay Description All enzymatic reactions were conducted in duplicate at room temperature for 17 hours in a 50 μl mixture containing HDAC assay buffer (50 mM Tris... | US Patent US10357493 (2019) BindingDB Entry DOI: 10.7270/Q2377C3H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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