Affinity Data by Patent

Patent code US10357546

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Collagenase (Homo sapiens (Human))	BDBM50335495 (4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM408486 (US10357546, ND-3640) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50264811 (CHEMBL485492 \| N-(4-(4-(thiiran-2-ylmethylsulfonyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM389618 (US10357546, ND-336 \| US9951035, ND-336 (5)) Show SMILES NCc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50388914 (CHEMBL2063274 \| US10357546, p-OH SB-3CT) Show SMILES Oc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50442356 (CHEMBL2442885 \| US10357546, ND-380 \| US9951035, ND...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50264809 (2-((4-phenoxyphenylsulfonyl)methyl)thiirane \| CHEM...) Show SMILES O=S(=O)(CC1CS1)c1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50354624 (CHEMBL1834422 \| US10357546, ND-322 \| US9951035, ND...) Show SMILES Nc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM408486 (US10357546, ND-3640) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50442355 (CHEMBL2442886 \| US10357546, ND-394) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50442363 (CHEMBL2442890 \| US10357546, ND-395) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50335495 (4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50264809 (2-((4-phenoxyphenylsulfonyl)methyl)thiirane \| CHEM...) Show SMILES O=S(=O)(CC1CS1)c1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50388914 (CHEMBL2063274 \| US10357546, p-OH SB-3CT) Show SMILES Oc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50354624 (CHEMBL1834422 \| US10357546, ND-322 \| US9951035, ND...) Show SMILES Nc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50264811 (CHEMBL485492 \| N-(4-(4-(thiiran-2-ylmethylsulfonyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM389618 (US10357546, ND-336 \| US9951035, ND-336 (5)) Show SMILES NCc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50442363 (CHEMBL2442890 \| US10357546, ND-395) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50442356 (CHEMBL2442885 \| US10357546, ND-380 \| US9951035, ND...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair
Collagenase (Homo sapiens (Human))	BDBM50442355 (CHEMBL2442886 \| US10357546, ND-394) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame du Lac US Patent					Assay Description Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...				US Patent US10357546 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K03
University of Notre Dame du Lac US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%