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Patent code US10364242

Compile Data Set for Download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-acylethanolamine-hydrolyzing acid amidase


(Homo sapiens (Human))
BDBM408807
PNG
(US10364242, ARN16186)
Show SMILES CCCCc1ccc(OC2CC3CCC(C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1
PDB

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UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 23n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

US Patent


Assay Description
h-NAAA: The assay was run in 96-well microplates (Black OptiPlate-96 F; PerkinElmer, Massachusetts, USA), in a total reaction volume of 200 μL. ...


US Patent US10364242 (2019)


BindingDB Entry DOI: 10.7270/Q2DJ5HZH
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens (Human))
BDBM408807
PNG
(US10364242, ARN16186)
Show SMILES CCCCc1ccc(OC2CC3CCC(C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a>3.00E+4n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

US Patent


Assay Description
h-AC:The assay was run in 96-well microplates (Black OptiPlate-96 F; PerkinElmer, Massachusetts, USA) in a total reaction volume of 100 μL. h-AC...


US Patent US10364242 (2019)


BindingDB Entry DOI: 10.7270/Q2DJ5HZH
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM408807
PNG
(US10364242, ARN16186)
Show SMILES CCCCc1ccc(OC2CC3CCC(C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>3.00E+4n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

US Patent


Assay Description
h-FAAH: The fluorescent assay to measure FAAH activity was performed in 96 wells black plates: 2.5 μg of human FAAH-1 membrane preparation were ...


US Patent US10364242 (2019)


BindingDB Entry DOI: 10.7270/Q2DJ5HZH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%