Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 8627
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408853(US10376531, Compound 3 | US10813942, Compound 3)
Affinity DataKd:  7.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408869(US10376531, Compound 31 | US10813942, Compound 31)
Affinity DataKd:  1.23E+4nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408855(US10376531, Compound 1 | US10813942, Compound 1)
Affinity DataKd:  9.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408856(US10376531, Compound 18 | US10813942, Compound 18)
Affinity DataKd:  3.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408857(US10376531, Compound 17 | US10813942, Compound 17)
Affinity DataKd:  5.30E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408858(US10376531, Compound 20 | US10813942, Compound 20)
Affinity DataKd:  2.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408859(US10376531, Compound 19 | US10813942, Compound 19)
Affinity DataKd:  3.30E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408860(US10376531, Compound 21 | US10813942, Compound 21)
Affinity DataKd:  3.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408861(US10376531, Compound 22 | US10813942, Compound 22)
Affinity DataKd:  5.50E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408862(US10376531, Compound 25 | US10813942, Compound 25)
Affinity DataKd:  2.20E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408863(US10376531, Compound 24 | US10813942, Compound 24)
Affinity DataKd:  1.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408864(US10376531, Compound 26 | US10813942, Compound 26)
Affinity DataKd:  6.00E+4nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408865(US10376531, Compound 29 | US10813942, Compound 29)
Affinity DataKd:  6.90E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408866(US10376531, Compound 30 | US10813942, Compound 30)
Affinity DataKd:  1.10E+5nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408867(US10376531, Compound 27 | US10813942, Compound 27)
Affinity DataKd:  700nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408868(US10376531, Compound 28 | US10813942, Compound 28)
Affinity DataKd:  1.20E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM408854(US10376531, Compound II-b | US10813942, Compound I...)
Affinity DataKd:  1.99E+5nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent