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Found 20 Enz. Inhib. hit(s) with all data for entry = 8632
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409054(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50:  27nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409053(6-(5-Fluoro-6-methylpyridin-3-yl)-3,3-dimethyl-1-(...)
Affinity DataIC50:  27nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409033(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50:  32.1nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409050(1-(6-Cyclopropyl-5-(methylsulfonyl)pyridin-3-yl)-3...)
Affinity DataIC50:  38.5nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409044(1-(5-(Cyclopropylsulfonyl)pyridin-3-yl)-3,3-dimeth...)
Affinity DataIC50:  40nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409034(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(6-(meth...)
Affinity DataIC50:  40.1nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409037(5-(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50:  44.9nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409049(5-(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50:  71.7nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409048(5-(3,3-dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50:  79.3nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409035(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(3-(meth...)
Affinity DataIC50:  106nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409046(5-(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-2-oxoin...)
Affinity DataIC50:  128nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409043(1-(5-(Isopropylsulfonyl)pyridin-3-yl)-3,3-dimethyl...)
Affinity DataIC50:  135nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409055(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50:  157nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409047(1-(5-(Azetidin-1-ylsulfonyl)pyridin-3-yl)-3,3-dime...)
Affinity DataIC50:  169nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409031(1-(Benzo[b]thiophen-6-yl)-3,3-dimethyl-6-(2-methyl...)
Affinity DataIC50:  189nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409045(3,3-Dimethyl-6-(2-methylpyrimidin-5-yl)-1-(5-(meth...)
Affinity DataIC50:  218nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409051(3,3-Dimethyl-6-(2-methyl-1-oxidopyrimidin-1-ium-5-...)
Affinity DataIC50:  218nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409056(6'-(2-Methylpyrimidin-5-yl)-1'-(5-(methylsulfonyl)...)
Affinity DataIC50:  230nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409052(3,3-Dimethyl-6-(5-methylpyridin-3-yl)-1-(5-(methyl...)
Affinity DataIC50:  313nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEquilibrative nucleoside transporter 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM409032(1-(Benzo[b]thiophen-4-yl)-3,3-dimethyl-6-(2-methyl...)
Affinity DataIC50:  844nMAssay Description:To measure adenosine transport activity of ENT-1 mammalian cells, stable cells expressing the mouse ENT-1 transporter were plated on day 1 in 96-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent