Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 8659
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411421(US10385052, Example 2)
Affinity DataIC50:  0.350nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411423(US10385052, Example 4)
Affinity DataIC50:  0.410nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411424(US10385052, Example 5)
Affinity DataIC50:  0.590nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411425(US10385052, Example 6)
Affinity DataIC50:  0.680nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411426(US10385052, Example 7)
Affinity DataIC50:  0.740nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411420(US10385052, Example 1)
Affinity DataIC50:  0.990nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411421(US10385052, Example 2)
Affinity DataIC50:  1.5nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411425(US10385052, Example 6)
Affinity DataIC50:  1.60nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411422(US10385052, Example 3)
Affinity DataIC50:  1.70nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411423(US10385052, Example 4)
Affinity DataIC50:  1.90nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411424(US10385052, Example 5)
Affinity DataIC50:  2nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411426(US10385052, Example 7)
Affinity DataIC50:  2nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411425(US10385052, Example 6)
Affinity DataIC50:  2.5nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411424(US10385052, Example 5)
Affinity DataIC50:  2.70nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411421(US10385052, Example 2)
Affinity DataIC50:  2.90nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411420(US10385052, Example 1)
Affinity DataIC50:  4.60nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411422(US10385052, Example 3)
Affinity DataIC50:  5.10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411426(US10385052, Example 7)
Affinity DataIC50:  5.10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411423(US10385052, Example 4)
Affinity DataIC50:  7.10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411422(US10385052, Example 3)
Affinity DataIC50:  10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411424(US10385052, Example 5)
Affinity DataIC50:  10nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411426(US10385052, Example 7)
Affinity DataIC50:  11nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411420(US10385052, Example 1)
Affinity DataIC50:  15nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411422(US10385052, Example 3)
Affinity DataIC50:  18nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411425(US10385052, Example 6)
Affinity DataIC50:  19nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411420(US10385052, Example 1)
Affinity DataIC50:  22nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411421(US10385052, Example 2)
Affinity DataIC50:  26nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nissan Chemical

US Patent
LigandPNGBDBM411423(US10385052, Example 4)
Affinity DataIC50:  39nMAssay Description:The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent