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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM411421 (US10385052, Example 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM411423 (US10385052, Example 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM411424 (US10385052, Example 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM411425 (US10385052, Example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM411426 (US10385052, Example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM411420 (US10385052, Example 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.990 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM411421 (US10385052, Example 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM411425 (US10385052, Example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM411422 (US10385052, Example 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM411423 (US10385052, Example 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM411426 (US10385052, Example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM411424 (US10385052, Example 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM411425 (US10385052, Example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM411424 (US10385052, Example 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM411421 (US10385052, Example 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM411420 (US10385052, Example 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM411426 (US10385052, Example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM411422 (US10385052, Example 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM411423 (US10385052, Example 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM411422 (US10385052, Example 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM411424 (US10385052, Example 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM411426 (US10385052, Example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM411420 (US10385052, Example 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM411422 (US10385052, Example 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM411425 (US10385052, Example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM411420 (US10385052, Example 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM411421 (US10385052, Example 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM411423 (US10385052, Example 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Nissan Chemical Corporation US Patent | Assay Description The JAK inhibitory activities of compounds of the present invention were measured.The enzymes (JAK1, JAK2, JAK3 and Tyk2) were purchased from Carna B... | US Patent US10385052 (2019) BindingDB Entry DOI: 10.7270/Q2154KC4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
