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Found 27 Enz. Inhib. hit(s) with all data for entry = 8677
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM103940(US10399973, Example 7 | US8569338, 7 | US9035066, ...)
Affinity DataIC50:  34nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM103941(US10399973, Example 14 | US8569338, 14 | US9035066...)
Affinity DataIC50:  48nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM103942(US10399973, Example 17 | US8569338, 24 | US9035066...)
Affinity DataIC50:  91nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412588(4-Chlorobenzyl 4-isopropyl-1,4,6,7-tetrahydro-5H-i...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412589(Pyridin-2-ylmethyl 4-isopropyl-1,4,6,7-tetrahydro-...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412590(Pyridin-4-ylmethyl 4-isopropyl-1,4,6,7-tetrahydro-...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412591((5-Chloropyridin-2-yl)methyl 4-isopropyl-1,4,6,7-t...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412592(Pyrazin-2-ylmethyl 4-isopropyl-1,4,6,7-tetrahydro-...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412593(Benzyl (4S,6S)-6-(aminocarbonyl)-4-isopropyl-1,4,6...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412594(Benzyl (4S,6S)-4-isopropyl-6-[(methylamino)carbony...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412595(5-Benzyl 6-methyl (4S,6S)-4-isopropyl-1,4,6,7-tetr...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412596(2-(4-Chlorophenoxy)ethyl 4-isopropyl-1,4,6,7-tetra...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412597((3S)-Tetrahydrofuran-3-yl (4S)-4-isopropyl-1,4,6,7...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412598((3-Methyloxetan-3-yl)methyl 4-isopropyl-1,4,6,7-te...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412599(2-(Dimethylamino)ethyl 4-isopropyl-1,4,6,7-tetrahy...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412600((2R)-Tetrahydrofuran-2-ylmethyl 4-isopropyl-1,4,6,...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412601(1,3-Thiazol-2-ylmethyl 4-Isopropyl-1,4,6,7-tetrahy...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412602((5-Methylisoxazol-3-yl)methyl 4-isopropyl-1,4,6,7-...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412603(US10399973, Example 23 | [(2S)-1-Methylpyrrolidin-...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412604((3R)-1-methylpyrrolidin-3-yl 4-isopropyl-1,4,6,7-t...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412605(Oxetan-2-ylmethyl 4-isopropyl-1,4,6,7-tetrahydro-5...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412606(2-(Pyridin-3-yloxy)ethyl 4-isopropyl-1,4,6,7-tetra...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412607(2-(2,2,2-Trifluoroethoxy)ethyl 4-isopropyl-1,4,6,7...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412587(3-Chlorobenzyl 4-isopropyl-1,4,6,7-tetrahydro-5H-i...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412586(Benzyl 4-isopropyl-1,4,6,7-tetrahydro-5H-imidazo[4...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412584(2,2,2-Trichloroethyl 4-isopropyl-1,4,6,7-tetrahydr...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Benevolentai Cambridge

US Patent
LigandPNGBDBM412585(2-Chloro-2,2-difluoroethyl 4-isopropyl-1,4,6,7-tet...)
Affinity DataIC50: <1.00E+3nMAssay Description:All assays were performed in room temperature with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent