Compile Data Set for Download or QSAR
maximum 50k data
Found 426 Enz. Inhib. hit(s) with all data for entry = 8687
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413341((S)-6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl...)
Affinity DataIC50:  1.78nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413007(6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol...)
Affinity DataIC50:  2.14nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413146(2-fluoro-4-(5-hydroxy-1-(5-(morpholine-4-carbonyl)...)
Affinity DataIC50:  2.24nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413152(2-fluoro-4-(5-hydroxy-1-(5-(4-methyl-4,7-diazaspir...)
Affinity DataIC50:  2.34nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413353((S)-6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyr...)
Affinity DataIC50:  2.51nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413246(4-(5-hydroxy-1-(5-(4-propylpiperazine-1-carbonyl)p...)
Affinity DataIC50:  2.51nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413134(2-fluoro-4-(5-hydroxy-1-(5-(4-methylpiperazine-1-c...)
Affinity DataIC50:  2.57nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413193((S)-4-(1-(5-(3-((2,2-difluoroethyl)(methyl)amino)p...)
Affinity DataIC50:  2.82nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413139(2-fluoro-4-(5-hydroxy-1-(5-(4-methyl-4,7-diazaspir...)
Affinity DataIC50:  2.88nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413210((R)-4-(1-(5-(3-((2,2-difluoroethyl)(methyl)amino)p...)
Affinity DataIC50:  2.95nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413140((S)-4-(1-(5-(4-ethyl-3-methylpiperazine-1-carbonyl...)
Affinity DataIC50:  3.02nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413063(4-(1-(5-(4-(2,2-difluoroethyl)piperazine-1-carbony...)
Affinity DataIC50:  3.09nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413199((R)-2-fluoro-4-(5-hydroxy-1-(5-(octahydropyrrolo[1...)
Affinity DataIC50:  3.16nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413069(4-(5-hydroxy-1-(5-(4-(2,2,2-trifluoroethyl)piperaz...)
Affinity DataIC50:  3.16nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413169((S)-4-(1-(5-(3,4-dimethylpiperazine-1-carbonyl)pyr...)
Affinity DataIC50:  3.16nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413158((S)-4-(1-(5-(3,4-dimethylpiperazine-1-carbonyl)pyr...)
Affinity DataIC50:  3.16nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413194(6-(4-(4-cyano-3-fluoro-2-methylphenyl)-5-hydroxy-1...)
Affinity DataIC50:  3.24nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413128((R)-4-(1-(5-(4-ethyl-3-methylpiperazine-1-carbonyl...)
Affinity DataIC50:  3.31nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413200(4-(5-hydroxy-1-(5-(octahydropyrrolo[1,2-a]pyrazine...)
Affinity DataIC50:  3.31nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413340(6-(4-(4-cyano-2-fluorophenyl)-5-hydroxy-1H-pyrazol...)
Affinity DataIC50:  3.31nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413188(6-(4-(4-cyano-5-fluoro-2-methylphenyl)-5-hydroxy-1...)
Affinity DataIC50:  3.31nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413187((S)-2-fluoro-4-(5-hydroxy-1-(5-(3-(methyl(2,2,2-tr...)
Affinity DataIC50:  3.39nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413157(2-fluoro-4-(5-hydroxy-1-(5-(morpholine-4-carbonyl)...)
Affinity DataIC50:  3.39nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413239((S)-4-(1-(5-(4-ethyl-2-methylpiperazine-1-carbonyl...)
Affinity DataIC50:  3.39nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM412995(4-(1-(5-(6,6-difluoro-4-methyl-1,4-diazepane-1-car...)
Affinity DataIC50:  3.47nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413335((R)-6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl...)
Affinity DataIC50:  3.47nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413347((R)-6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyr...)
Affinity DataIC50:  3.55nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413164((R)-4-(1-(5-(3,4-dimethylpiperazine-1-carbonyl)pyr...)
Affinity DataIC50:  3.63nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413023(4-(5-hydroxy-1-(5-(3,3,4-trimethylpiperazine-1-car...)
Affinity DataIC50:  3.63nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413145(2-fluoro-4-(5-hydroxy-1-(5-(pyrrolidine-1-carbonyl...)
Affinity DataIC50:  3.63nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413205(2-fluoro-4-(5-hydroxy-1-(5-(3-(piperidin-1-yl)azet...)
Affinity DataIC50:  3.72nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413011(6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol...)
Affinity DataIC50:  3.89nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413246(4-(5-hydroxy-1-(5-(4-propylpiperazine-1-carbonyl)p...)
Affinity DataIC50:  3.89nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413148(6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol...)
Affinity DataIC50:  3.98nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413121(4-(1-(5-(3-(dimethylamino)azetidine-1-carbonyl)pyr...)
Affinity DataIC50:  3.98nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413223(6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-...)
Affinity DataIC50:  3.98nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413221((R)-4-(1-(5-(4-ethyl-3-methylpiperazine-1-carbonyl...)
Affinity DataIC50:  3.98nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413104(6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol...)
Affinity DataIC50:  3.98nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413098(6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol...)
Affinity DataIC50:  3.98nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM412984(4-(1-(5-(3-(cyclobutyl(methyl)amino)azetidine-1-ca...)
Affinity DataIC50:  4.07nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413240(4-(1-(5-(4-cyclopropylpiperazine-1-carbonyl)pyridi...)
Affinity DataIC50:  4.07nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413233((R)-4-(1-(5-(3,4-dimethylpiperazine-1-carbonyl)pyr...)
Affinity DataIC50:  4.07nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413039(4-(1-(5-(4-cyclopropylpiperazine-1-carbonyl)pyridi...)
Affinity DataIC50:  4.07nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413163((S)-4-(1-(5-(4-ethyl-3-methylpiperazine-1-carbonyl...)
Affinity DataIC50:  4.07nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413216((R)-2-fluoro-4-(5-hydroxy-1-(5-(4-isopropyl-3-meth...)
Affinity DataIC50:  4.37nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413317(6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-...)
Affinity DataIC50:  4.37nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413263(4-(1-(5-(3-(dimethylamino)azetidine-1-carbonyl)pyr...)
Affinity DataIC50:  4.47nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413105((S)-4-(1-(5-(3-(dimethylamino)pyrrolidine-1-carbon...)
Affinity DataIC50:  4.47nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413175((R)-4-(1-(5-(4-ethyl-2-methylpiperazine-1-carbonyl...)
Affinity DataIC50:  4.57nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413151(6-(4-(4-cyano-3-fluoro-2-methylphenyl)-5-hydroxy-1...)
Affinity DataIC50:  4.68nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
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