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Patent code US10421765

Compile Data Set for Download or QSAR
Found 101 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATR/ATRIP


(Homo sapiens (Human))
BDBM414107
PNG
((R)-7-methyl-6-(2- methyl-1H-pyrrolo[2,3- b]pyridi...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1ccnc2[nH]c(C)cc12
PDB

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US Patent
n/an/a 51n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414074
PNG
((R)-6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl)-7...)
Show SMILES C[C@@H]1Cc2ncnc(C3=CC4CCC(C3)N4S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 66n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414085
PNG
(N-((S)-1-((R)-6-(6- chloro-1H-pyrrolo[2,3-b]- pyri...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC[C@@H](C3)NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 73n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414112
PNG
((R)-6-(6-cyclobutoxy-1H- pyrrolo[2,3-b]pyridin-4- ...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1cc(OC2CCC2)nc2[nH]ccc12
PDB

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n/an/a 75n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414077
PNG
(Methyl (S)-1-((R)-6-(6- chloro-1H-pyrrolo[2,3- b]p...)
Show SMILES COC(=O)[C@H]1CCCN(C1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 86n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414084
PNG
(2-((R)-1-((R)-6-(6- chloro-1H-pyrrolo[2,3-b]- pyri...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC[C@H](C3)C(C)(C)O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 87n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414106
PNG
((R)-6-(6-isopropoxy-1H- pyrrolo[2,3-b]pyridin-4- y...)
Show SMILES CC(C)Oc1cc(N2Cc3c(C[C@H]2C)ncnc3C2CCN(CC2)S(C)(=O)=O)c2cc[nH]c2n1
PDB

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n/an/a 87n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414110
PNG
((R)-6-(6-cyclopropoxy- 1H-pyrrolo[2,3-b]pyridin- 4...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1cc(OC2CC2)nc2[nH]ccc12
PDB

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n/an/a 93n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414093
PNG
((R)-1-(6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC(C3)C#N)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 103n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414087
PNG
(N-(4-((R)-6-(6-chloro- 1H-pyrrolo[2,3-b]pyridin- 4...)
Show SMILES C[C@@H]1Cc2ncnc(C3=CCC(CC3)NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 111n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414099
PNG
((R)-N-(1-(7-methyl-6- (1H-pyrrolo[2,3-b]- pyridin-...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC(C3)NS(=O)(=O)C3CC3)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 113n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414024
PNG
(US10421765, Example 13 | US10745420, Example 13)
Show SMILES CNC1[C@H]2CC[C@@H]1CN(C2)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 114n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414040
PNG
(N-{1-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- ...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 120n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414066
PNG
(US10421765, Example 54 | US10745420, Example 56)
Show SMILES CCOc1cc(N2Cc3c(C[C@H]2C)ncnc3C2CCN(CC2)S(C)(=O)=O)c2cc[nH]c2n1
PDB

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n/an/a 123n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414103
PNG
((R)-7-methyl-4-(1- (methylsulfonyl)piperidin- 4-yl...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1cnc2cn[nH]c2c1
PDB

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n/an/a 138n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414081
PNG
((S)-1-((R)-6-(6-chloro- 1H-pyrrolo[2,3-b]pyridin- ...)
Show SMILES CNC(=O)[C@H]1CCCN(C1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 140n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414079
PNG
((7R)-6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl)-...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCCC(C3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 159n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414017
PNG
(US10421765, Example 7 | US10745420, Example 9)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 163n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414044
PNG
(2-{1-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- ...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC(C3)C(C)(C)O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 183n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414092
PNG
(N-((1R,5S,8R)-3-((R)-6- (6-chloro-1H-pyrrolo[2,3- ...)
Show SMILES C[C@@H]1Cc2ncnc(N3C[C@@H]4CC[C@H](C3)[C@@H]4NS(=O)(=O)C3CC3)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 184n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414043
PNG
(1-[(7R)-6-{6-chloro-1H- pyrrolo[2,3-b]pyridin-4- y...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC(C3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 223n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414101
PNG
((R)-6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl)-7...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC[C@H](C3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 237n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414095
PNG
((R)-1-(7-methyl-6-(1H- pyrrolo[2,3-b]pyridin-4- yl...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC(C3)C#N)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 246n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414089
PNG
((R)-1-(6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(O)(CC3)C3CC3)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 246n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414076
PNG
(Methyl (R)-1-((R)-6-(6- chloro-1H-pyrrolo[2,3- b]p...)
Show SMILES COC(=O)[C@@H]1CCCN(C1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 253n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414104
PNG
((R)-6-(6-methoxy-1H- pyrrolo[2,3-b]pyridin-4- yl)-...)
Show SMILES COc1cc(N2Cc3c(C[C@H]2C)ncnc3C2CCN(CC2)S(C)(=O)=O)c2cc[nH]c2n1
PDB

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n/an/a 269n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414108
PNG
((R)-6-(6-cyclopropyl-1H- pyrrolo[2,3-b]pyridin-4- ...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1cc(nc2[nH]ccc12)C1CC1
PDB

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US Patent
n/an/a 270n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414088
PNG
(N-((1R,5S,8R)-3-((R)-7- methyl-6-(1H-pyrrolo- [2,3...)
Show SMILES C[C@@H]1Cc2ncnc(C3C[C@@H]4CC[C@H](C3)[C@@H]4NS(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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US Patent
n/an/a 279n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414054
PNG
(US10421765, Example 46 | US10745420, Example 46)
Show SMILES CCC1(O)CCN(CC1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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US Patent
n/an/a 282n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414083
PNG
(N-(3-((R)-7-methyl-6- (1H-pyrrolo[2,3-b]- pyridin-...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC4CCC(C3)C4NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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US Patent
n/an/a 283n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414055
PNG
(US10421765, Example 47 | US10745420, Example 47)
Show SMILES C[C@@H]1Cc2ncnc(C3CN(C3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 287n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414068
PNG
(US10421765, Example 55b | US10745420, Example 55b)
Show SMILES CCOc1cc(N2Cc3c(C[C@@H]2CF)ncnc3C2CCN(CC2)S(C)(=O)=O)c2cc[nH]c2n1
PDB

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n/an/a 311n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414091
PNG
((R)-1-(6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC(O)C3)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 320n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414109
PNG
((R)-7-methyl-4-(1- (methylsulfonyl)piperidin- 4-yl...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1cc(OCC(F)(F)F)nc2[nH]ccc12
PDB

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US Patent
n/an/a 321n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414022
PNG
(US10421765, Example 11b)
Show SMILES C[C@@H]1Cc2ncnc([C@@H]3C[C@@H]4CC[C@H](C3)N4S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 329n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414041
PNG
(2-{1-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- ...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)C(C)(C)O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 329n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414100
PNG
((R)-6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl)-7...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC[C@@H](C3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 329n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414111
PNG
((R)-4-(7-methyl-4-(1- (methylsulfonyl)piperidin- 4...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1cc(nc2[nH]ccc12)C#N
PDB

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n/an/a 336n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414097
PNG
(1-((R)-7-methyl-6-(1H- pyrrolo[2,3-b]pyridin-4- yl...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCCC(C3)C#N)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 364n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414053
PNG
(US10421765, Example 45 | US10745420, Example 45)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC[C@@H](C3)C(C)(C)O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 378n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414020
PNG
(US10421765, Example 10 | US10745420, Example 10)
Show SMILES COC(=O)N1CCCC(C1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 408n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414029
PNG
(3-methanesulfonyl-1- [(7R)-7-methyl-6-{1H- pyrrolo...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCCC(C3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 420n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414045
PNG
(1-[(7R)-6-{6-chloro-1H- pyrrolo[2,3-b]pyridin-4- y...)
Show SMILES CNC(=O)C1CN(C1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 429n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414042
PNG
(8-[(7R)-6-{6-chloro-1H- pyrrolo[2,3-b]pyridin-4- y...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC4(CNC(=O)O4)CC3)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 434n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414057
PNG
(US10421765, Example 48b)
Show SMILES C[C@@H]1Cc2ncnc([C@@H]3CCN(C(C)(C)C3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 435n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414019
PNG
(US10421765, Example 9)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 442n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414078
PNG
((R)-N-(1-(7-methyl-6- (1H-pyrrolo[2,3-b]- pyridin-...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)NS(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 472n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414049
PNG
((7R)-6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl)-...)
Show SMILES CC1CCN(C1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 472n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414082
PNG
((R)-6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl)-4...)
Show SMILES COC1CCN(CC1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 475n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414016
PNG
(US10421765, Example 6 | US10745420, Example 8)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 499n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414075
PNG
((R)-8-(6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC4(CC3)NC(=O)NC4=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 514n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414023
PNG
(US10421765, Example 12 | US10745420, Example 12)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(O)CC3)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 518n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414021
PNG
(US10421765, Example 11a)
Show SMILES C[C@@H]1Cc2ncnc([C@H]3C[C@@H]4CC[C@H](C3)N4S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 555n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414061
PNG
(US10421765, Example 51a)
Show SMILES C[C@@H]1Cc2ncnc([C@@H]3CCCN(C)C3)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 561n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414080
PNG
((R)-1-(6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(C)(O)CC3)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 584n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414018
PNG
(US10421765, Example 8 | US10421765, Example 88 | U...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 615n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414090
PNG
((R)-1-(6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl...)
Show SMILES CNC(=O)C1CCN(CC1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 708n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414086
PNG
(N-((R)-1-((R)-6-(6- chloro-1H-pyrrolo[2,3-b]- pyri...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC[C@H](C3)NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 715n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414098
PNG
((R)-N-(1-(7-methyl-6- (1H-pyrrolo[2,3-b]- pyridin-...)
Show SMILES C[C@@H]1Cc2ncnc(N3CC(C3)NS(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 722n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414069
PNG
(US10421765, Example 56)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1cc(C)nc2[nH]ccc12
PDB

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n/an/a 773n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414096
PNG
((R)-1-(7-methyl-6-(1H- pyrrolo[2,3-b]pyridin-4- yl...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)C#N)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 796n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414015
PNG
(US10421765, Example 4 | US10745420, Example 4)
Show SMILES CC1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 833n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414070
PNG
(US10421765, Example 57a)
Show SMILES C[C@@H]1Cc2ncnc([C@H]3CCN(C)C3)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 840n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414064
PNG
(US10421765, Example 52b | US10745420, Example 52b)
Show SMILES CS(=O)(=O)N1CCC(CC1)c1ncnc2C[C@H](CF)N(Cc12)c1ccnc2[nH]ccc12
PDB

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n/an/a 878n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414048
PNG
((R)-N-(4-(6-(6-chloro- 1H-pyrrolo[2,3-b]pyridin- 4...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCC(CC3)NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 899n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414036
PNG
(US10421765, Example 25 | US10745420, Example 25 | ...)
Show SMILES COC(=O)N1CCC(CC1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 899n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414047
PNG
(N-((1R,5S)-(8-anti)-3- ((R)-6-(6-chloro-1H- pyrrol...)
Show SMILES C[C@@H]1Cc2ncnc(N3C[C@@H]4CC[C@H](C3)[C@H]4NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 929n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414028
PNG
(1-methanesulfonyl-3- [(7R)-7-methyl-6-{1H- pyrrolo...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(C3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 936n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414072
PNG
(US10421765, Example 58 | US10745420, Example 58)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)S(C)(=N)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 966n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414018
PNG
(US10421765, Example 8 | US10421765, Example 88 | U...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 979n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414052
PNG
(US10421765, Example 44 | US10745420, Example 44)
Show SMILES CNC(=O)[C@@H]1CCCN(C1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 1.04E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414094
PNG
((R)-4-(1-(cyclopropyl- sulfonyl)piperidin-4-yl)- 7...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(=O)(=O)C3CC3)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 1.09E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414059
PNG
(US10421765, Example 50a)
Show SMILES C[C@@H]1Cc2ncnc([C@@H]3CCCN(C3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 1.20E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414105
PNG
(7-(fluoromethyl-4-(1- (methylsulfonyl)- piperidin-...)
Show SMILES CS(=O)(=O)N1CCC(CC1)c1ncnc2CC(CF)N(Cc12)c1ccnc2[nH]ccc12
PDB

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n/an/a 1.29E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414071
PNG
(US10421765, Example 57b)
Show SMILES C[C@@H]1Cc2ncnc([C@@H]3CCN(C)C3)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 1.47E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414014
PNG
(US10421765, Example 3)
Show SMILES CC1Cc2ncnc(-c3ccc(cc3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 1.97E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414062
PNG
(US10421765, Example 51b)
Show SMILES C[C@@H]1Cc2ncnc([C@H]3CCCN(C)C3)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 2.21E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414065
PNG
(US10421765, Example 53b)
Show SMILES CS(=O)(=O)N1CCC(CC1)c1ncnc2C[C@H](C(F)F)N(Cc12)c1ccnc2[nH]ccc12
PDB

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n/an/a 2.42E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414073
PNG
(US10421765, Example 59 | US10745420, Example 59)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1nccc2[nH]ccc12
PDB

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n/an/a 2.65E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414056
PNG
(US10421765, Example 48a)
Show SMILES C[C@@H]1Cc2ncnc([C@H]3CCN(C(C)(C)C3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 3.33E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414027
PNG
(1-methanesulfonyl-3- [(7R)-7-methyl-6-{1H- pyrrolo...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCCN(C3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 3.57E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414058
PNG
(US10421765, Example 49 | US10745420, Example 49)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)C(=O)C(C)(C)O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 3.60E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414060
PNG
(US10421765, Example 50b)
Show SMILES C[C@@H]1Cc2ncnc([C@H]3CCCN(C3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 4.79E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414032
PNG
(4-[(7R)-6-{6-chloro-1H- pyrrolo[2,3-b]pyridin-4- y...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCN(C(C)(C)C3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414039
PNG
(US10421765, Example 28 | US10745420, Example 28 | ...)
Show SMILES COC(=O)NC1[C@H]2CC[C@@H]1CN(C2)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414038
PNG
(N-[3-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- ...)
Show SMILES CCC(=O)NC1[C@H]2CC[C@@H]1CN(C2)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414013
PNG
(US10421765, Example 2 | US10745420, Example 2)
Show SMILES CS(=O)(=O)N1CCC(CC1)c1ncnc2CCN(Cc12)c1ccnc2[nH]ccc12
Show InChI InChI=1S/C20H24N6O2S/c1-29(27,28)26-10-4-14(5-11-26)19-16-12-25(9-6-17(16)23-13-24-19)18-3-8-22-20-15(18)2-7-21-20/h2-3,7-8,13-14H,4-6,9-12H2,1H3,(H,21,22)
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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414037
PNG
(N-{3-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- ...)
Show SMILES C[C@@H]1Cc2ncnc(N3C[C@@H]4CC[C@H](C3)C4NC(=O)CC(F)(F)F)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414050
PNG
((R)-7-methyl-4-(1- (methylsulfonyl)piperidin- 4-yl...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ncc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414025
PNG
(4-(3-methanesulfonyl- phenyl)-6-{1H-pyrrolo- [2,3-...)
Show SMILES CS(=O)(=O)c1cccc(c1)-c1ncnc2CCN(Cc12)c1ccnc2[nH]ccc12
Show InChI InChI=1S/C21H19N5O2S/c1-29(27,28)15-4-2-3-14(11-15)20-17-12-26(10-7-18(17)24-13-25-20)19-6-9-23-21-16(19)5-8-22-21/h2-6,8-9,11,13H,7,10,12H2,1H3,(H,22,23)
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414035
PNG
(3-[(7R)-6-{6-chloro-1H- pyrrolo[2,3-b]pyridin-4- y...)
Show SMILES CCS(=O)(=O)N1CCCC(C1)c1ncnc2C[C@@H](C)N(Cc12)c1ccnc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414026
PNG
(4-(3-methanesulfonyl- phenyl)-7-methyl-6-{1H- pyrr...)
Show SMILES CC1Cc2ncnc(-c3cccc(c3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414030
PNG
(1-methanesulfonyl-4- [(7R)-7-methyl-6-{1H- pyrrolo...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCCN(CC3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414012
PNG
(US10421765, Example 1 | US10745420, Example 1)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ncnc2CCN(Cc12)c1ccnc2[nH]ccc12
Show InChI InChI=1S/C21H19N5O2S/c1-29(27,28)15-4-2-14(3-5-15)20-17-12-26(11-8-18(17)24-13-25-20)19-7-10-23-21-16(19)6-9-22-21/h2-7,9-10,13H,8,11-12H2,1H3,(H,22,23)
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414033
PNG
(4-[(7R)-6-{6-chloro-1H- pyrrolo[2,3-b]pyridin-4- y...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCS(=O)(=O)CC3)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414046
PNG
((R)-6-(6-chloro-1H- pyrrolo[2,3-b]pyridin-4- yl)-7...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCC33CN(C3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414034
PNG
(1-methanesulfonyl-4- [(7R)-7-methyl-6-{7H- pyrrolo...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1ncnc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414031
PNG
(1-[(7R)-6-{6-chloro-1H- pyrrolo[2,3-b]pyridin-4- y...)
Show SMILES C[C@@H]1Cc2ncnc(N3CCN(CC3)S(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414034
PNG
(1-methanesulfonyl-4- [(7R)-7-methyl-6-{7H- pyrrolo...)
Show SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1ncnc2[nH]ccc12
PDB

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n/an/a 5.50E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414067
PNG
(US10421765, Example 55a | US10745420, Example 55a)
Show SMILES CCOc1cc(N2Cc3c(C[C@H]2CF)ncnc3C2CCN(CC2)S(C)(=O)=O)c2cc[nH]c2n1
PDB

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n/an/a 2.50E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
ATR/ATRIP


(Homo sapiens (Human))
BDBM414063
PNG
(US10421765, Example 52a | US10745420, Example 52a)
Show SMILES CS(=O)(=O)N1CCC(CC1)c1ncnc2C[C@@H](CF)N(Cc12)c1ccnc2[nH]ccc12
PDB

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n/an/a 3.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...


US Patent US10421765 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RHH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%