Compile Data Set for Download or QSAR
maximum 50k data
Found 98 Enz. Inhib. hit(s) with all data for entry = 8740
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415679(US10428108, Example 88)
Affinity DataIC50:  2nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415662(US10428108, Example 72 | US10428108, Example 93)
Affinity DataIC50:  2nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415683(US10428108, Example 92)
Affinity DataIC50:  3nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415659(US10428108, Example 69)
Affinity DataIC50:  3nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415661(US10428108, Example 71)
Affinity DataIC50:  3nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415671(US10428108, Example 81)
Affinity DataIC50:  4nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415680(US10428108, Example 89)
Affinity DataIC50:  4nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415690(US10428108, Example 98)
Affinity DataIC50:  7nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415665(US10428108, Example 75)
Affinity DataIC50:  7nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415655(US10428108, Example 65 | US10428108, Example 74 | ...)
Affinity DataIC50:  8nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415663(US10428108, Example 73)
Affinity DataIC50:  8nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415667(US10428108, Example 77 | US10428108, Example 79)
Affinity DataIC50:  8nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415670(US10428108, Example 80)
Affinity DataIC50:  9nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415639(US10428108, Example 50)
Affinity DataIC50:  10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415645(US10428108, Example 55)
Affinity DataIC50:  10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415646(US10428108, Example 56)
Affinity DataIC50:  10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415648(US10428108, Example 58)
Affinity DataIC50:  10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415649(US10428108, Example 59)
Affinity DataIC50:  10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415652(US10428108, Example 62 | US10428108, Example 94)
Affinity DataIC50:  10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415660(US10428108, Example 70)
Affinity DataIC50:  10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415667(US10428108, Example 77 | US10428108, Example 79)
Affinity DataIC50:  10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415674((4S)-4-[[(2S)-2-[[2-(3,5-Dichlorophenoxy)acetyl]am...)
Affinity DataIC50:  10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415655(US10428108, Example 65 | US10428108, Example 74 | ...)
Affinity DataIC50:  15nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415644(US10428108, Example 54)
Affinity DataIC50:  15nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415678(US10428108, Example 87)
Affinity DataIC50:  16nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415688(US10428108, Example 96)
Affinity DataIC50:  16nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415655(US10428108, Example 65 | US10428108, Example 74 | ...)
Affinity DataIC50:  19nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415654(US10428108, Example 64)
Affinity DataIC50:  20nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415616(US10428108, Example 27)
Affinity DataIC50:  20nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415642(US10428108, Example 53)
Affinity DataIC50:  20nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415647(US10428108, Example 57)
Affinity DataIC50:  20nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415677(US10428108, Example 86)
Affinity DataIC50:  21nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415617(US10428108, Example 28)
Affinity DataIC50:  25nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415689(US10428108, Example 97)
Affinity DataIC50:  25nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415638(US10428108, Example 49)
Affinity DataIC50:  30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415653(US10428108, Example 63)
Affinity DataIC50:  30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415641(US10428108, Example 52)
Affinity DataIC50:  30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415629(US10428108, Example 40)
Affinity DataIC50:  30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415656(US10428108, Example 66)
Affinity DataIC50:  30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415666(US10428108, Example 76)
Affinity DataIC50:  32nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415597(US10428108, Example 9)
Affinity DataIC50:  33nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415675(US10428108, Example 84)
Affinity DataIC50:  34nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415662(US10428108, Example 72 | US10428108, Example 93)
Affinity DataIC50:  36nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415676(US10428108, Example 85)
Affinity DataIC50:  38nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415658(US10428108, Example 68)
Affinity DataIC50:  40nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415637(US10428108, Example 48)
Affinity DataIC50:  40nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415650(US10428108, Example 60)
Affinity DataIC50:  40nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415651(US10428108, Example 61)
Affinity DataIC50:  40nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415640(US10428108, Example 51)
Affinity DataIC50:  40nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415590((4S)-4-[[(2S)-2-[[(E)-3-(3,5-Dichlorophenyl)prop-2...)
Affinity DataIC50:  40nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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