BindingDB logo
myBDB logout

Patent code US10435408

Compile Data Set for Download or QSAR
Found 19 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458557
PNG
(CHEMBL4215875)
Show SMILES Cc1ccc(cc1)-c1noc2CCNCCc12
Show InChI InChI=1S/C14H16N2O/c1-10-2-4-11(5-3-10)14-12-6-8-15-9-7-13(12)17-16-14/h2-5,15H,6-9H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
16n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458555
PNG
(CHEMBL4207884)
Show SMILES Clc1ccc(cc1)-c1n[nH]c2CCNCCc12
Show InChI InChI=1S/C13H14ClN3/c14-10-3-1-9(2-4-10)13-11-5-7-15-8-6-12(11)16-17-13/h1-4,15H,5-8H2,(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
30n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458558
PNG
(CHEMBL4210782)
Show SMILES Cc1ccc(cc1)-c1n[nH]c2CCNCCc12
Show InChI InChI=1S/C14H17N3/c1-10-2-4-11(5-3-10)14-12-6-8-15-9-7-13(12)16-17-14/h2-5,15H,6-9H2,1H3,(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
47n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458553
PNG
(CHEMBL4218672)
Show SMILES Fc1ccc(cc1)-c1noc2CCNCCc12
Show InChI InChI=1S/C13H13FN2O/c14-10-3-1-9(2-4-10)13-11-5-7-15-8-6-12(11)17-16-13/h1-4,15H,5-8H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
53n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458554
PNG
(CHEMBL4218801)
Show SMILES Clc1ccc(cc1)-c1noc2CCNCCc12
Show InChI InChI=1S/C13H13ClN2O/c14-10-3-1-9(2-4-10)13-11-5-7-15-8-6-12(11)17-16-13/h1-4,15H,5-8H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
70n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM417123
PNG
(3-(2-methoxyphenyl)-5,6,7,8-tetrahydro-4H-isoxazol...)
Show SMILES COc1ccccc1-c1noc2CCNCCc12
Show InChI InChI=1S/C14H16N2O2/c1-17-12-5-3-2-4-10(12)14-11-6-8-15-9-7-13(11)18-16-14/h2-5,15H,6-9H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
303n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458562
PNG
(CHEMBL4215925)
Show SMILES C1Cc2onc(c2CCN1)-c1ccccc1
Show InChI InChI=1S/C13H14N2O/c1-2-4-10(5-3-1)13-11-6-8-14-9-7-12(11)16-15-13/h1-5,14H,6-9H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
319n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458552
PNG
(CHEMBL4213135)
Show SMILES C1Cc2[nH]nc(c2CCN1)-c1ccccc1
Show InChI InChI=1S/C13H15N3/c1-2-4-10(5-3-1)13-11-6-8-14-9-7-12(11)15-16-13/h1-5,14H,6-9H2,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
322n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458567
PNG
(CHEMBL4206411)
Show SMILES Fc1ccccc1-c1noc2CCNCCc12
Show InChI InChI=1S/C13H13FN2O/c14-11-4-2-1-3-9(11)13-10-5-7-15-8-6-12(10)17-16-13/h1-4,15H,5-8H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
366n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458568
PNG
(CHEMBL4207073)
Show SMILES Clc1cccc(c1)-c1noc2CCNCCc12
Show InChI InChI=1S/C13H13ClN2O/c14-10-3-1-2-9(8-10)13-11-4-6-15-7-5-12(11)17-16-13/h1-3,8,15H,4-7H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
369n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458560
PNG
(CHEMBL4214171)
Show SMILES Clc1ccccc1-c1n[nH]c2CCNCCc12
Show InChI InChI=1S/C13H14ClN3/c14-11-4-2-1-3-9(11)13-10-5-7-15-8-6-12(10)16-17-13/h1-4,15H,5-8H2,(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
386n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458564
PNG
(CHEMBL4213067)
Show SMILES Clc1ccccc1-c1noc2CCNCCc12
Show InChI InChI=1S/C13H13ClN2O/c14-11-4-2-1-3-9(11)13-10-5-7-15-8-6-12(10)17-16-13/h1-4,15H,5-8H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
425n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458565
PNG
(CHEMBL4207901)
Show SMILES Cc1cccc(c1)-c1noc2CCNCCc12
Show InChI InChI=1S/C14H16N2O/c1-10-3-2-4-11(9-10)14-12-5-7-15-8-6-13(12)17-16-14/h2-4,9,15H,5-8H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
506n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458566
PNG
(CHEMBL4205846)
Show SMILES Fc1ccccc1-c1n[nH]c2CCNCCc12
Show InChI InChI=1S/C13H14FN3/c14-11-4-2-1-3-9(11)13-10-5-7-15-8-6-12(10)16-17-13/h1-4,15H,5-8H2,(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
714n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458551
PNG
(CHEMBL4215197)
Show SMILES Cc1ccccc1-c1n[nH]c2CCNCCc12
Show InChI InChI=1S/C14H17N3/c1-10-4-2-3-5-11(10)14-12-6-8-15-9-7-13(12)16-17-14/h2-5,15H,6-9H2,1H3,(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
881n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458556
PNG
(CHEMBL4202995)
Show SMILES Clc1cccc(c1)-c1n[nH]c2CCNCCc12
Show InChI InChI=1S/C13H14ClN3/c14-10-3-1-2-9(8-10)13-11-4-6-15-7-5-12(11)16-17-13/h1-3,8,15H,4-7H2,(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
883n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458561
PNG
(CHEMBL4217548)
Show SMILES Fc1cccc(c1)-c1n[nH]c2CCNCCc12
Show InChI InChI=1S/C13H14FN3/c14-10-3-1-2-9(8-10)13-11-4-6-15-7-5-12(11)16-17-13/h1-3,8,15H,4-7H2,(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
1.24E+3n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458563
PNG
(CHEMBL4211303)
Show SMILES Fc1cccc(c1)-c1noc2CCNCCc12
Show InChI InChI=1S/C13H13FN2O/c14-10-3-1-2-9(8-10)13-11-4-6-15-7-5-12(11)17-16-13/h1-3,8,15H,4-7H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
1.41E+3n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50458559
PNG
(CHEMBL4203526)
Show SMILES Cc1cccc(c1)-c1n[nH]c2CCNCCc12
Show InChI InChI=1S/C14H17N3/c1-10-3-2-4-11(9-10)14-12-5-7-15-8-6-13(12)16-17-14/h2-4,9,15H,5-8H2,1H3,(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
1.44E+3n/an/an/an/an/an/an/an/a



Korea Institute of Science and Technology

US Patent


Assay Description
Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...


US Patent US10435408 (2019)


BindingDB Entry DOI: 10.7270/Q2ZS2ZXP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%