Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 8817
LigandPNGBDBM420317(5-Bromo-3-(sec-butoxy)-N-((4,6-dimethyl-2-oxo-1,2-...)
Affinity DataIC50:  13nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM420310(2-Methyl-3-[(1-methylethyl)amino]-N-[(6-methyl-2-o...)
Affinity DataIC50:  40nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM420312(5-Bromo-2-methyl-3-[(1-methylethyl)amino]-N-{[6-me...)
Affinity DataIC50:  50nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM420316(2,5-Dichloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-...)
Affinity DataIC50:  250nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM420317(5-Bromo-3-(sec-butoxy)-N-((4,6-dimethyl-2-oxo-1,2-...)
Affinity DataIC50:  316nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM420308(5-Bromo-2-methyl-3-[(1-methylethyl)amino]-N-[(6-me...)
Affinity DataIC50:  501nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM420319(5—Chloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyri...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM50193711(CHEMBL3955846 | US10478426, Example 36)
Affinity DataIC50:  2.50E+3nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
In DepthDetails US Patent