BindingDB logo
myBDB logout

Patent code US10479798

Compile Data Set for Download or QSAR
Found 32 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM50198186
PNG
(CHEMBL3944427 | US10479798, Compound 19)
Show SMILES COc1cc2c3C[C@H](N)[C@H](Oc3ccc2cc1S(C)(=O)=O)c1cc(F)c(F)cc1F
Show InChI InChI=1/C21H18F3NO4S/c1-28-19-8-11-10(5-20(19)30(2,26)27)3-4-18-12(11)7-17(25)21(29-18)13-6-15(23)16(24)9-14(13)22/h3-6,8-9,17,21H,7,25H2,1-2H3/t17-,21+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM50003020
PNG
(MK-3102 | OMARIGLIPTIN | US10155775, Omarigliptin ...)
Show SMILES CS(=O)(=O)n1cc2CN(Cc2n1)[C@H]1CO[C@@H]([C@@H](N)C1)c1cc(F)ccc1F
Show InChI InChI=1/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17-/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420962
PNG
(US10479798, Compound 21)
Show SMILES COc1cc2c3C[C@H](N)[C@H](Oc3ccc2cc1C#N)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C21H15F3N2O2/c1-27-20-7-12-10(4-11(20)9-25)2-3-19-13(12)6-18(26)21(28-19)14-5-16(23)17(24)8-15(14)22/h2-5,7-8,18,21H,6,26H2,1H3/t18-,21+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PDB
UniChem
PDB
US Patent
n/an/a 2n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420415
PNG
(US10479798, Compound 12)
Show SMILES COc1cc2ccc3OC([C@@H](N)Cc3c2cc1OC)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C21H18F3NO3/c1-26-19-5-10-3-4-18-12(11(10)8-20(19)27-2)7-17(25)21(28-18)13-6-15(23)16(24)9-14(13)22/h3-6,8-9,17,21H,7,25H2,1-2H3/t17-,21?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM50198175
PNG
(CHEMBL3932825 | US10479798, Compound 17)
Show SMILES CS(=O)(=O)c1ccc2c3C[C@H](N)[C@H](Oc3ccc2c1)c1cc(F)c(F)cc1F
Show InChI InChI=1/C20H16F3NO3S/c1-28(25,26)11-3-4-12-10(6-11)2-5-19-13(12)8-18(24)20(27-19)14-7-16(22)17(23)9-15(14)21/h2-7,9,18,20H,8,24H2,1H3/t18-,20+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420402
PNG
(US10479798, Compound 9)
Show SMILES N[C@H]1Cc2c(O[C@@H]1c1cc(F)c(F)cc1F)ccc1cc(ccc21)C#N
Show InChI InChI=1S/C20H13F3N2O/c21-15-8-17(23)16(22)6-14(15)20-18(25)7-13-12-3-1-10(9-24)5-11(12)2-4-19(13)26-20/h1-6,8,18,20H,7,25H2/t18-,20+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 9.17n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420956
PNG
(US10479798, Compound 16)
Show SMILES CS(=O)(=O)Nc1ccc2c3CC(N)C(Oc3ccc2c1)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C20H17F3N2O3S/c1-29(26,27)25-11-3-4-12-10(6-11)2-5-19-13(12)8-18(24)20(28-19)14-7-16(22)17(23)9-15(14)21/h2-7,9,18,20,25H,8,24H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM11162
PNG
((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F
Show InChI InChI=1/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Similars

PDB
US Patent
n/an/a 14n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM50198180
PNG
(CHEMBL3928073 | US10479798, Compound 5)
Show SMILES COc1ccc2ccc3O[C@@H]([C@@H](N)Cc3c2c1)c1cc(F)c(F)cc1F
Show InChI InChI=1/C20H16F3NO2/c1-25-11-4-2-10-3-5-19-13(12(10)6-11)8-18(24)20(26-19)14-7-16(22)17(23)9-15(14)21/h2-7,9,18,20H,8,24H2,1H3/t18-,20+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 15n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420408
PNG
(US10479798, Compound 10)
Show SMILES NC1Cc2c(OC1c1cc(F)c(F)cc1F)ccc1cc(OC=O)ccc21
Show InChI InChI=1S/C20H14F3NO3/c21-15-8-17(23)16(22)6-14(15)20-18(24)7-13-12-3-2-11(26-9-25)5-10(12)1-4-19(13)27-20/h1-6,8-9,18,20H,7,24H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 18n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM50198178
PNG
(CHEMBL3901191 | US10479798, Compound 6)
Show SMILES COc1ccc2c3C[C@H](N)[C@H](Oc3ccc2c1)c1cc(F)c(F)cc1F
Show InChI InChI=1/C20H16F3NO2/c1-25-11-3-4-12-10(6-11)2-5-19-13(12)8-18(24)20(26-19)14-7-16(22)17(23)9-15(14)21/h2-7,9,18,20H,8,24H2,1H3/t18-,20+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 20n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM50198184
PNG
(CHEMBL3942843 | US10479798, Compound 20)
Show SMILES COc1cc2c3C[C@H](N)[C@H](Oc3ccc2cc1NS(C)(=O)=O)c1cc(F)c(F)cc1F
Show InChI InChI=1/C21H19F3N2O4S/c1-29-20-8-11-10(5-18(20)26-31(2,27)28)3-4-19-12(11)7-17(25)21(30-19)13-6-15(23)16(24)9-14(13)22/h3-6,8-9,17,21,26H,7,25H2,1-2H3/t17-,21+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420966
PNG
(US10479798, Compound 25)
Show SMILES COc1ccc2ccc3OC(C(N)Cc3c2c1)c1cc(F)ccc1F
Show InChI InChI=1S/C20H17F2NO2/c1-24-13-5-2-11-3-7-19-15(14(11)9-13)10-18(23)20(25-19)16-8-12(21)4-6-17(16)22/h2-9,18,20H,10,23H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 33n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM50198185
PNG
(CHEMBL3979508 | US10479798, Compound 7)
Show SMILES N[C@H]1Cc2c(O[C@@H]1c1cc(F)c(F)cc1F)ccc1cc(Br)ccc21
Show InChI InChI=1/C19H13BrF3NO/c20-10-2-3-11-9(5-10)1-4-18-12(11)7-17(24)19(25-18)13-6-15(22)16(23)8-14(13)21/h1-6,8,17,19H,7,24H2/t17-,19+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 39n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420971
PNG
(US10479798, Compound 30)
Show SMILES COc1cc2ccc3OC(C(N)Cc3c2cc1OC)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H19Cl2NO3/c1-25-19-7-11-3-6-18-15(14(11)10-20(19)26-2)9-17(24)21(27-18)13-5-4-12(22)8-16(13)23/h3-8,10,17,21H,9,24H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420969
PNG
(US10479798, Compound 28)
Show SMILES COc1cc2ccc3OC(C(N)Cc3c2cc1OC)c1ccc(F)cc1F
Show InChI InChI=1S/C21H19F2NO3/c1-25-19-7-11-3-6-18-15(14(11)10-20(19)26-2)9-17(24)21(27-18)13-5-4-12(22)8-16(13)23/h3-8,10,17,21H,9,24H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 56n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420958
PNG
(US10479798, Compound 18)
Show SMILES NC1Cc2c(OC1c1cc(F)c(F)cc1F)ccc1cc(ccc21)N1CCOCC1
Show InChI InChI=1S/C23H21F3N2O2/c24-18-12-20(26)19(25)10-17(18)23-21(27)11-16-15-3-2-14(28-5-7-29-8-6-28)9-13(15)1-4-22(16)30-23/h1-4,9-10,12,21,23H,5-8,11,27H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 70n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420477
PNG
(US10479798, Compound 14)
Show SMILES N[C@H]1Cc2c(O[C@@H]1c1cc(F)c(F)cc1F)ccc1ccc(cc21)-c1cccc(CS(=O)=O)c1
Show InChI InChI=1S/C26H20F3NO3S/c27-21-12-23(29)22(28)10-20(21)26-24(30)11-19-18-9-17(5-4-15(18)6-7-25(19)33-26)16-3-1-2-14(8-16)13-34(31)32/h1-10,12,24,26,34H,11,13,30H2/t24-,26+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 74n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420965
PNG
(US10479798, Compound 24)
Show SMILES COc1ccc2ccc3OC(C(N)Cc3c2c1)c1ccc(F)cc1F
Show InChI InChI=1S/C20H17F2NO2/c1-24-13-5-2-11-3-7-19-16(15(11)9-13)10-18(23)20(25-19)14-6-4-12(21)8-17(14)22/h2-9,18,20H,10,23H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 78n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420854
PNG
(US10479798, Compound 15)
Show SMILES NC1Cc2c(OC1c1cc(F)c(F)cc1F)ccc1ccccc21
Show InChI InChI=1S/C19H14F3NO/c20-14-9-16(22)15(21)7-13(14)19-17(23)8-12-11-4-2-1-3-10(11)5-6-18(12)24-19/h1-7,9,17,19H,8,23H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 110n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM50198164
PNG
(CHEMBL3959577 | US10479798, Compound 3)
Show SMILES Cc1cc(=O)oc2c3C[C@H](N)[C@H](Oc3ccc12)c1cc(F)c(F)cc1F
Show InChI InChI=1/C19H14F3NO3/c1-8-4-17(24)26-18-9(8)2-3-16-11(18)6-15(23)19(25-16)10-5-13(21)14(22)7-12(10)20/h2-5,7,15,19H,6,23H2,1H3/t15-,19+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 154n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420453
PNG
(US10479798, Compound 13)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2ccc3OC(C(N)Cc3c2c1)c1cc(F)c(F)cc1F
Show InChI InChI=1S/C26H20F3NO3S/c1-34(31,32)17-7-4-14(5-8-17)16-3-2-15-6-9-25-19(18(15)10-16)12-24(30)26(33-25)20-11-22(28)23(29)13-21(20)27/h2-11,13,24,26H,12,30H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 169n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420412
PNG
(US10479798, Compound 11)
Show SMILES NC1Cc2c(OC1c1cc(F)c(F)cc1F)ccc1ccc(cc21)C#N
Show InChI InChI=1S/C20H13F3N2O/c21-15-8-17(23)16(22)6-14(15)20-18(25)7-13-12-5-10(9-24)1-2-11(12)3-4-19(13)26-20/h1-6,8,18,20H,7,25H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 205n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420328
PNG
(US10479798, Compound 2)
Show SMILES NC1Cc2c(OC1c1cc(F)c(F)cc1F)ccc1ccc(=O)oc21
Show InChI InChI=1S/C18H12F3NO3/c19-11-7-13(21)12(20)5-9(11)18-14(22)6-10-15(24-18)3-1-8-2-4-16(23)25-17(8)10/h1-5,7,14,18H,6,22H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 207n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420400
PNG
(US10479798, Compound 8)
Show SMILES NC1Cc2c(OC1c1cc(F)c(F)cc1F)ccc1ccc(Br)cc21
Show InChI InChI=1S/C19H13BrF3NO/c20-10-3-1-9-2-4-18-12(11(9)5-10)7-17(24)19(25-18)13-6-15(22)16(23)8-14(13)21/h1-6,8,17,19H,7,24H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 216n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420970
PNG
(US10479798, Compound 29)
Show SMILES COc1cc2ccc3OC(C(N)Cc3c2cc1OC)c1ccccc1
Show InChI InChI=1S/C21H21NO3/c1-23-19-10-14-8-9-18-16(15(14)12-20(19)24-2)11-17(22)21(25-18)13-6-4-3-5-7-13/h3-10,12,17,21H,11,22H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 254n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420338
PNG
(US10479798, Compound 4)
Show SMILES NC1Cc2cc(O)ccc2OC1c1cc(F)c(F)cc1F
Show InChI InChI=1S/C15H12F3NO2/c16-10-6-12(18)11(17)5-9(10)15-13(19)4-7-3-8(20)1-2-14(7)21-15/h1-3,5-6,13,15,20H,4,19H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 283n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420967
PNG
(US10479798, Compound 26)
Show SMILES COc1ccc2ccc3OC(C(N)Cc3c2c1)c1ccccc1Cl
Show InChI InChI=1S/C20H18ClNO2/c1-23-13-8-6-12-7-9-19-16(15(12)10-13)11-18(22)20(24-19)14-4-2-3-5-17(14)21/h2-10,18,20H,11,22H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 338n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420963
PNG
(US10479798, Compound 22)
Show SMILES COc1ccc2ccc3OC(C(N)Cc3c2c1)c1ccccc1F
Show InChI InChI=1S/C20H18FNO2/c1-23-13-8-6-12-7-9-19-16(15(12)10-13)11-18(22)20(24-19)14-4-2-3-5-17(14)21/h2-10,18,20H,11,22H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 564n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420968
PNG
(US10479798, Compound 27)
Show SMILES COc1ccc2ccc3OC(C(N)Cc3c2c1)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H17Cl2NO2/c1-24-13-5-2-11-3-7-19-16(15(11)9-13)10-18(23)20(25-19)14-6-4-12(21)8-17(14)22/h2-9,18,20H,10,23H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 678n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420964
PNG
(US10479798, Compound 23)
Show SMILES COc1ccc2ccc3OC(C(N)Cc3c2c1)c1ccc(F)cc1
Show InChI InChI=1S/C20H18FNO2/c1-23-15-8-4-12-5-9-19-17(16(12)10-15)11-18(22)20(24-19)13-2-6-14(21)7-3-13/h2-10,18,20H,11,22H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 800n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM420322
PNG
(US10479798, Compound 1)
Show SMILES NC1Cc2c(O)cccc2OC1c1cc(F)c(F)cc1F
Show InChI InChI=1S/C15H12F3NO2/c16-9-6-11(18)10(17)4-7(9)15-12(19)5-8-13(20)2-1-3-14(8)21-15/h1-4,6,12,15,20H,5,19H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
UniChem
US Patent
n/an/a 3.32E+3n/an/an/an/an/an/a



EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

US Patent


Assay Description
Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...


US Patent US10479798 (2019)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%