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Found 38 Enz. Inhib. hit(s) with all data for entry = 8803
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420027(US10487087, Compound I)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420065(2-cyclopentyl-N-((1-isopropylazetidin-2- yl)methyl...)
Affinity DataEC50:  1.20E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420029((S)-2-Cyclopentyl-N-((1-isopropylpyrrolidin-2-yl)m...)
Affinity DataEC50:  4.60E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420030((R)-2-cyclopentyl-N-((1-isopropylpyrrolidin-2- yl)...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420030((R)-2-cyclopentyl-N-((1-isopropylpyrrolidin-2- yl)...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420031(2-cyclopentyl-N-(((S)-1-isopropylpyrrolidin-2- yl)...)
Affinity DataEC50:  5.70E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420031(2-cyclopentyl-N-(((S)-1-isopropylpyrrolidin-2- yl)...)
Affinity DataEC50:  1.10E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420032(N-(((S)-1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50:  2.40E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420032(N-(((S)-1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50:  2.90E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420033(N-(((R)-1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50:  4.20E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420033(N-(((R)-1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50:  5.90E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420034((S)-2-cyclopentyl-8-fluoro-N-((1- isopropylpyrroli...)
Affinity DataEC50:  4.40E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420034((S)-2-cyclopentyl-8-fluoro-N-((1- isopropylpyrroli...)
Affinity DataEC50:  6.10E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420037((R)-2-cyclopentyl-8-fluoro-N-((1- isopropylpyrroli...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420037((R)-2-cyclopentyl-8-fluoro-N-((1- isopropylpyrroli...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420038((R)-2-cyclopentyl-N-(((S)-1-isopropylpyrrolidin-2-...)
Affinity DataEC50:  3.60E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420038((R)-2-cyclopentyl-N-(((S)-1-isopropylpyrrolidin-2-...)
Affinity DataEC50:  3.60E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420039((S)-2-cyclopentyl-N-(((S)-1-isopropylpyrrolidin-2-...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420039((S)-2-cyclopentyl-N-(((S)-1-isopropylpyrrolidin-2-...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420043((S)-10-chloro-2-cyclopentyl-N-((1- isopropylpyrrol...)
Affinity DataEC50:  1.30E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420043((S)-10-chloro-2-cyclopentyl-N-((1- isopropylpyrrol...)
Affinity DataEC50:  1.50E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420044((R)-10-chloro-2-cyclopentyl-N-((1- isopropylpyrrol...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420044((R)-10-chloro-2-cyclopentyl-N-((1- isopropylpyrrol...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420047((S)-10-bromo-2-cyclopentyl-N-((1- isopropylpyrroli...)
Affinity DataEC50:  2.20E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420047((S)-10-bromo-2-cyclopentyl-N-((1- isopropylpyrroli...)
Affinity DataEC50:  3.60E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420048((R)-10-bromo-2-cyclopentyl-N-((1- isopropylpyrroli...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420048((R)-10-bromo-2-cyclopentyl-N-((1- isopropylpyrroli...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420049((S)-N-((1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50:  1.30E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420050((R)-N-((1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420051((S)-10-cyano-2-cyclopentyl-N-((1- isopropylpyrroli...)
Affinity DataEC50:  1.90E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420052((S)-2-cyclopentyl-N-((1-isopropylpyrrolidin-2- yl)...)
Affinity DataEC50:  9.60E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420054((S)-N-((1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50:  6.70E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420055((R)-N-((1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420056((S)-N-((1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50:  5.20E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420057((R)-N-((1-isopropylpyrrolidin-2-yl)methyl)-10- met...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420059(N-(azetidin-2-ylmethyl)-2-cyclopentyl-10-methyl- 1...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420061(2-cyclopentyl-4-(hydroxymethyl)-10- methylpyrazino...)
Affinity DataEC50: >3.00E+4nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM420029((S)-2-Cyclopentyl-N-((1-isopropylpyrrolidin-2-yl)m...)
Affinity DataEC50:  2.70E+3nMAssay Description:To assess the effects of test compounds on GLP-1 or glucagon potency and efficacy, a high-throughput calcium mobilization assay was used essentially ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent