Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 8846
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423161(6-(1,5-dimethyl-6-oxo-3-pyridyl)-8-(2-pyridylmethy...)
Affinity DataIC50:  110nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423156(5-benzyl-6-(1,5-dimethyl-6-oxo-3-pyridyl)-3,4-dihy...)
Affinity DataIC50:  140nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423168(6-(1,5-dimethyl-6-oxo-3-pyridyl)-8-(N-methylanilin...)
Affinity DataIC50:  180nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423159(5-benzyl-6-(1,5-dimethyl-6-oxo-3-pyridyl)-1-methyl...)
Affinity DataIC50:  270nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423154(US10501438, Compound 4)
Affinity DataIC50:  280nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423166(7-benzyl-6-(1,5-dimethyl-6-oxo-3-pyridyl)-3,4-dihy...)
Affinity DataIC50:  280nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423163(6-(1,5-dimethyl-6-oxo-3-pyridyl)-8-(N-methylanilin...)
Affinity DataIC50:  350nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423160(6-(1,5-dimethyl-6-oxo-3-pyridyl)-8-(3-pyridylamino...)
Affinity DataIC50:  350nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423151(US10501438, Compound 1)
Affinity DataIC50:  410nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423164(6-(1,5-dimethyl-6-oxo-3-pyridyl)-8-(tetrahydropyra...)
Affinity DataIC50:  420nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423167(5-benzyl-6-(1,5-dimethyl-6-oxo-3-pyridyl)-1-methyl...)
Affinity DataIC50:  480nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423153(US10501438, Compound 3)
Affinity DataIC50:  510nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423152(US10501438, Compound 2)
Affinity DataIC50:  560nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423165(US10501438, Compound 19)
Affinity DataIC50:  700nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423155(8-(cyclohexylamino)-6-(1,5-dimethyl-6-oxo-3-pyridy...)
Affinity DataIC50:  810nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423162(6-(1,5-dimethyl-6-oxo-3-pyridyl)-8-(1-piperidylmet...)
Affinity DataIC50:  1.30E+3nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent