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Found 10 Enz. Inhib. hit(s) with all data for entry = 8880
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM247206(US10513524, Compound (P4) | US11608342, Compound (...)
Affinity DataIC50:  10nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM247220(US10513524, Compound (P2) | US9434733, 2-[[3-(3-py...)
Affinity DataIC50:  36nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM426311(US10513524, Compound (P1))
Affinity DataIC50:  42nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50:  49nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50397838(CHEMBL2179105 | PF-04447943 | US10513524, Referenc...)
Affinity DataIC50:  70nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
LigandPNGBDBM247206(US10513524, Compound (P4) | US11608342, Compound (...)
Affinity DataIC50:  1.01E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50397838(CHEMBL2179105 | PF-04447943 | US10513524, Referenc...)
Affinity DataIC50:  2.50E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50:  3.00E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM247220(US10513524, Compound (P2) | US9434733, 2-[[3-(3-py...)
Affinity DataIC50:  5.28E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM426311(US10513524, Compound (P1))
Affinity DataIC50:  4.51E+4nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent