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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM333120 ((S)-(3-(dimethylamino)azetidin-1-yl)(2-(6-(2-ethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM431908 (US10550118, Example 8-15) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM333120 ((S)-(3-(dimethylamino)azetidin-1-yl)(2-(6-(2-ethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431910 (US10550118, Example 8-17) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431902 (US10550118, Example 8-9) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431913 (US10550118, Example 8-20) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM333145 ((S)-(3-(dimethylamino)-3-methylazetidin-1-yl)(5-et...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431914 (US10550118, Example 8-21) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431895 (US10550118, Example 8-2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM333122 ((S)-(3-(dimethylamino)-3-methylazetidin-1-yl)(2-(6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM333120 ((S)-(3-(dimethylamino)azetidin-1-yl)(2-(6-(2-ethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431899 (US10550118, Example 8-6) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431906 (US10550118, Example 8-13 | US10550118, Example 8-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431894 (US10550118, Example 8-1) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431896 (US10550118, Example 8-3) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431905 (US10550118, Example 8-12) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM333144 ((S)-(3-(dimethylamino)azetidin-1-yl)(5-ethyl-2-(6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM333121 ((S)-(3-(dimethylamino)azetidin-1-yl)(2-(6-(2-ethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431897 (US10550118, Example 8-4) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM333136 ((S)-(5-ethyl-2-(6-(2-ethyl-5-fluoro-4-hydroxypheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431903 (US10550118, Example 8-10) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431901 (US10550118, Example 8-8) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431908 (US10550118, Example 8-15) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431898 (US10550118, Example 8-5) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431906 (US10550118, Example 8-13 | US10550118, Example 8-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431909 (US10550118, Example 8-16) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM333120 ((S)-(3-(dimethylamino)azetidin-1-yl)(2-(6-(2-ethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431904 (US10550118, Example 8-11) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK1/TYK2 (Homo sapiens (Human)) | BDBM431911 (US10550118, Example 8-18) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431910 (US10550118, Example 8-17) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431897 (US10550118, Example 8-4) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM333121 ((S)-(3-(dimethylamino)azetidin-1-yl)(2-(6-(2-ethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431902 (US10550118, Example 8-9) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431896 (US10550118, Example 8-3) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM333122 ((S)-(3-(dimethylamino)-3-methylazetidin-1-yl)(2-(6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431894 (US10550118, Example 8-1) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431913 (US10550118, Example 8-20) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM333145 ((S)-(3-(dimethylamino)-3-methylazetidin-1-yl)(5-et...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM333120 ((S)-(3-(dimethylamino)azetidin-1-yl)(2-(6-(2-ethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431898 (US10550118, Example 8-5) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431906 (US10550118, Example 8-13 | US10550118, Example 8-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM333136 ((S)-(5-ethyl-2-(6-(2-ethyl-5-fluoro-4-hydroxypheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431899 (US10550118, Example 8-6) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431914 (US10550118, Example 8-21) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431895 (US10550118, Example 8-2) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431905 (US10550118, Example 8-12) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431901 (US10550118, Example 8-8) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431904 (US10550118, Example 8-11) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431903 (US10550118, Example 8-10) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431906 (US10550118, Example 8-13 | US10550118, Example 8-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM333144 ((S)-(3-(dimethylamino)azetidin-1-yl)(5-ethyl-2-(6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM333120 ((S)-(3-(dimethylamino)azetidin-1-yl)(2-(6-(2-ethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431911 (US10550118, Example 8-18) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431909 (US10550118, Example 8-16) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| JAK3/JAK1 (Homo sapiens (Human)) | BDBM431908 (US10550118, Example 8-15) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM431908 (US10550118, Example 8-15) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma R&D IP, LLC US Patent | Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%... | US Patent US10550118 (2020) BindingDB Entry DOI: 10.7270/Q25D8V88 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
