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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433292 (6-amino-2-(3- (aminomethyl)-3- methylpyrrolidin-1-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433311 (3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433296 (N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433305 (3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433310 (3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433316 ((R)-3-(3-amino-3H- spiro[benzofuran-2,4'- piperidi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433290 (3-(4-(aminomethyl)-4- methylpiperidin-1-yl)-6- ((2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433308 (4-((5-(4-(aminomethyl)-4- methylpiperidin-1-yl)-6-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433298 (N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433312 (3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433293 (6-(4-(aminomethyl)-4- methylpiperidin-1-yl)-3- ((2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433301 (3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433297 (N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433303 (1-(3-aminocyclohexyl)-4- (2,3- dichlorophenyl)pyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433315 ((S)-3-(1-amino-1,3- dihydrospiro[indene-2,4'- pipe...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433302 ((S)-3-(4-amino-2-oxa-8- azaspiro[4.5]decan-8-yl)- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433304 (N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433317 ((S)-3-(4-amino-2-oxa-8- azaspiro[4.5]decan-8-yl)- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433294 (6-((2-amino-3- chloropyridin-4-yl)thio)-3- ((3S,4S...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433295 (N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433306 (3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433307 (3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433313 (3-(2- aminospiro[bicyclo[3.1.0] hexane-3,4'-piperi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433300 (N-(3-((5-(4- (aminomethyl)-4- methylpiperidin-1-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433314 (3-(6-amino-3- azabicyclo[3.1.0]hexan-3- yl)-6-((2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433309 (3-((3S,4S)-4-amino-3- methyl-2-oxa-8- azaspiro[4.5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-tyrosine phosphatase 2C (Homo sapiens (Human)) | BDBM433291 (6-(4-(aminomethyl)-4- methylpiperidin-1-yl)-3- (2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
SYNBLia Therapeutics, Inc. US Patent | Assay Description IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as... | US Patent US10561655 (2020) BindingDB Entry DOI: 10.7270/Q23F4S2Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
