Affinity Data by Patent

Patent code US10562844

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433365 (US10562844, Compound 16) Show SMILES OC(=O)C1CSC(O)(O)C1 Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	2.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433361 (US10562844, Compound 13) Show SMILES OC(=O)C1CSC(=O)C1 Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	3.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433364 (US10562844, Compound 14) Show SMILES O[C@@H]1C[C@H](CS1)C(O)=O Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	3.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433363 (US10562844, Compound 15) Show SMILES O[C@H]1C[C@H](CS1)C(O)=O Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	3.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433359 (US10562844, Compound 11) Show SMILES OC(=O)[C@@H]1CCC(=O)C1 Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	3.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433358 (US10562844, Compound 10) Show SMILES OC(=O)C1CCC(=O)C1 Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433360 (US10562844, Compound 8) Show SMILES O[C@H]1CC[C@H](CC(O)=O)C1 Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	4.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433357 (US10562844, Compound 7) Show SMILES O[C@H]1CCC(C1)C(O)=O Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433355 (US10562844, Compound 9) Show SMILES N[C@H]1CCC(C1)C(O)=O Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	6.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433362 (US10562844, Compound 12) Show SMILES OC1CC(CS1)C(O)=O Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	<1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433354 (US10562844, Compound 2) Show SMILES OC(=O)C1CCCO1 Show InChI	GoogleScholar	PDB UniChem	US Patent	n/a	n/a	1.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433351 (US10562844, Compound 5) Show SMILES OC1CCC(C1)C(O)=O Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	2.10E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433349 (US10562844, Compound 1) Show SMILES CC1CC(NN1)C(O)=O Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	2.90E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair
Hydroxyproline dehydrogenase (HYPDH)(147-515) (Homo sapiens (Human))	BDBM433356 (US10562844, Compound 6) Show SMILES O[C@@H]1CCC(C1)C(O)=O Show InChI	GoogleScholar	UniChem	US Patent	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences; UAB Research Foundation US Patent					Assay Description In an effort to biochemically and structurally characterize human HYPDH, we have evaluated numerous expression constructs (>15) in Escherichia coli w...				US Patent US10562844 (2020) BindingDB Entry DOI: 10.7270/Q2KH0QQ5
					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%