Affinity Data by Patent

Patent code US10570077

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Baculoviral IAP repeat-containing protein 2/Estrogen receptor (Homo sapiens (Human))	BDBM50494960 (CHEMBL3099430 \| US10570077, Compound 7) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a
Marquette University; Concordia University Inc. US Patent					Assay Description Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...				US Patent US10570077 (2020) BindingDB Entry DOI: 10.7270/Q2P271H9
Marquette University; Concordia University Inc. US Patent					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2/Estrogen receptor (Homo sapiens (Human))	BDBM50494963 (CHEMBL3099431 \| US10570077, Compound 13) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a
Marquette University; Concordia University Inc. US Patent					Assay Description Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...				US Patent US10570077 (2020) BindingDB Entry DOI: 10.7270/Q2P271H9
Marquette University; Concordia University Inc. US Patent					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2/Estrogen receptor (Homo sapiens (Human))	BDBM435391 (US10570077, Compound 2) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a
Marquette University; Concordia University Inc. US Patent					Assay Description Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...				US Patent US10570077 (2020) BindingDB Entry DOI: 10.7270/Q2P271H9
Marquette University; Concordia University Inc. US Patent					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2/Estrogen receptor (Homo sapiens (Human))	BDBM435383 (US10570077, Compound E2) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a
Marquette University; Concordia University Inc. US Patent					Assay Description Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...				US Patent US10570077 (2020) BindingDB Entry DOI: 10.7270/Q2P271H9
Marquette University; Concordia University Inc. US Patent					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2/Estrogen receptor (Homo sapiens (Human))	BDBM435385 (US10570077, Compound 4) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a
Marquette University; Concordia University Inc. US Patent					Assay Description Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...				US Patent US10570077 (2020) BindingDB Entry DOI: 10.7270/Q2P271H9
Marquette University; Concordia University Inc. US Patent					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2/Estrogen receptor (Homo sapiens (Human))	BDBM435392 (US10570077, Compound 18) Show SMILES OC[C@H]1C=CC[C@H](C=C1)c1ccc(O)cc1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Marquette University; Concordia University Inc. US Patent					Assay Description Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...				US Patent US10570077 (2020) BindingDB Entry DOI: 10.7270/Q2P271H9
Marquette University; Concordia University Inc. US Patent					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2/Estrogen receptor (Homo sapiens (Human))	BDBM50494961 (CHEMBL3099428 \| US10570077, Compound 11) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a
Marquette University; Concordia University Inc. US Patent					Assay Description Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...				US Patent US10570077 (2020) BindingDB Entry DOI: 10.7270/Q2P271H9
Marquette University; Concordia University Inc. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%