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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374393 (US10246456, Example 573 | US10577367, Example 573) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374395 (US10246456, Example 575 | US10577367, Example 575) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374404 (US10246456, Example 586 | US10577367, Example 586) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374412 (US10246456, Example 595 | US10577367, Example 414) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM433289 (N-methyl-1-(3-(1-(6-methylpyridin-2-yl)-1H-indazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374070 (2-(6-(5-aminopyridin-3-yl)-1H-indazol-1-yl)pyrimid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374071 (5-(1-(6-(trifluoromethyl)pyridin-2-yl)-1H-indazol-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374076 (US10246456, Example 49 | US10577367, Example 49 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374079 (6-(5-aminopyridin-3-yl)-1-(6-(trifluoromethyl)pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374082 (US10246456, Example 56 | US10577367, Example 57 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374084 (6-(6-(1-aminoethyl)pyridin-2-yl)-N-methyl-1-(6-(tr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374088 (6-(6-(5-aminopyridin-3-yl)imidazo[1,5-a]pyridin-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374091 (2-(aminomethyl)-6-(1-(6-(trifluoromethyl)pyridin-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374096 (3-amino-N-(2-aminoethyl)-5-(1-(6-(trifluoromethyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374107 (6-(6-(1-aminoethyl)pyridin-2-yl)-N-methyl-1-(6-met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374123 ((S)-(6-(6-(6-(1-aminoethyl)pyridin-2-yl)-1H-indazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374129 (US10246456, Example 214 | US10577367, Example 214) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374090 (1-(6-(3-(6-(trifluoromethyl)pyridin-2-yl)imidazo[1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374140 (US10246456, Example 247 | US10577367, Example 247) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374157 (US10246456, Example 279 | US10577367, Example 279) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374169 (US10246456, Example 302 | US10577367, Example 302) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374180 (US10246456, Example 318 | US10577367, Example 318) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374181 (US10246456, Example 319 | US10577367, Example 319) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374185 (US10246456, Example 325 | US10577367, Example 325) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374192 (US10246456, Example 332 | US10577367, Example 332) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374208 (US10246456, Example 348 | US10577367, Example 348) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374214 (US10246456, Example 355 | US10577367, Example 355) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374219 (US10246456, Example 360 | US10577367, Example 360) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374221 (US10246456, Example 362 | US10577367, Example 362) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374246 (US10246456, Example 387 | US10577367, Example 387) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM433497 ((R)-N-((S)-1-(6-(1-(6-acetylpyridin-2-yl)-1H-indaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374275 ((6-(6-(8-amino-8-propyl-5,6,7,8-tetrahydroquinolin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374283 ((4S)-4-amino-3-fluoro-4-(6-(1-(6-(hydroxymethyl)py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM433512 (Step 1. Synthesis of 1-(6-bromopyridin-2-yl)-2-flu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374293 ((S)-(6-(6-(6-(1-aminopent-3-yn-1-yl)pyridin-2-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374297 ((6-(6-(6-((1R,2R)-1-amino-2-methoxybutyl)pyridin-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM433529 (Step 1. Synthesis of (R)-2-methyl-N—((S)-1-(6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374310 ((S)-(6-(6-(6-(1-aminoethyl)pyridin-2-yl)-4-(3-meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374318 ((6-(6-(6-(1-aminocyclobutyl)pyridin-2-yl)-4-(2-met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374325 ((6-(6-(6-((S)-1-aminobutyl)pyridin-2-yl)-4-(tetrah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374326 ((6-(6-(6-((S)-1-aminobutyl)pyridin-2-yl)-4-((2R,5R...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374334 (US10246456, Example 486 | US10577367, Example 486) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374356 (US10246456, Example 509 | US10577367, Example 509) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374361 (US10246456, Example 514 | US10577367, Example 514) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374364 (US10246456, Example 517 | US10577367, Example 517) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374383 (US10246456, Example 538 | US10577367, Example 538) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374387 (US10246456, Example 544 | US10577367, Example 544) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374398 (US10246456, Example 578 | US10577367, Example 578) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374078 (6-(5-aminopyridin-3-yl)-1-(6-(trifluoromethyl)pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM374080 ((6-(5-aminopyridin-3-yl)-1-(6-(trifluoromethyl)pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
BIOGEN MA INC. US Patent | Assay Description The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho... | US Patent US10577367 (2020) BindingDB Entry DOI: 10.7270/Q2765HRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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