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Found 12 Enz. Inhib. hit(s) with all data for entry = 8993
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434878(((1aR,2S,5R,5aS,6S,8aS,9R,10aR)-6-(((4-chloropheny...)
Affinity DataEC50:  7nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434941(((1aR,2S,5R,5aS,6S,8aS,9R,10aR)-6-(((4-chloropheny...)
Affinity DataEC50:  22nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434942((1aR,2S,5R,5aS,6S,8aS,9R,10aR)-4-((1,3-dioxoisoind...)
Affinity DataEC50:  1.11E+3nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434943((1aR,2S,5R,5aS,8aS,9R,10aR)-5,5a-dihydroxy-4-(hydr...)
Affinity DataEC50:  4.94E+3nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434945(((1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-...)
Affinity DataEC50:  616nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434952((1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-1...)
Affinity DataEC50:  5.17E+3nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434947(((1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-...)
Affinity DataEC50:  1.05E+3nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434948(((1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-...)
Affinity DataEC50:  4.33E+3nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434949(((1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-...)
Affinity DataEC50:  5.00E+4nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434950(((1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-...)
Affinity DataEC50:  278nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434951((1aR,2S,5R,5aS,6S,8aS,9R,10aR)-5,5a-dihydroxy-4-((...)
Affinity DataEC50:  3.50E+3nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM434946(((1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-...)
Affinity DataEC50:  3.68E+3nMAssay Description:For the Jurkat HIV Latency assay, compounds are dissolved and titrated in DMSO and diluted 100-fold in assay medium (RPMI-1640 containing 10% fetal b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent