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Patent code US10584116

Compile Data Set for Download or QSAR
Found 51 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435036
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N-[[3- is...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2C=CCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H24F4N4O6S/c1-16(2)36-26(38)18(15-34(27(36)39)21-8-5-19(6-9-21)28(30,31)32)14-33-25(37)22-4-3-11-35(22)43(40,41)24-13-17-12-20(29)7-10-23(17)42-24/h3-10,12-13,15-16,22H,11,14H2,1-2H3,(H,33,37)/t22-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM434986
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N-[[3- is...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H26F4N4O6S/c1-16(2)36-26(38)18(15-34(27(36)39)21-8-5-19(6-9-21)28(30,31)32)14-33-25(37)22-4-3-11-35(22)43(40,41)24-13-17-12-20(29)7-10-23(17)42-24/h5-10,12-13,15-16,22H,3-4,11,14H2,1-2H3,(H,33,37)/t22-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435041
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N-[[1- is...)
Show SMILES CC(C)n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cc(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C29H27F4N3O5S/c1-17(2)35-16-18(12-23(28(35)38)19-5-7-21(8-6-19)29(31,32)33)15-34-27(37)24-4-3-11-36(24)42(39,40)26-14-20-13-22(30)9-10-25(20)41-26/h5-10,12-14,16-17,24H,3-4,11,15H2,1-2H3,(H,34,37)/t24-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435038
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N-[[3- is...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H24F4N4O6S/c1-15(2)35-25(37)17(14-33(26(35)38)20-6-3-18(4-7-20)27(29,30)31)13-32-24(36)21-9-10-34(21)42(39,40)23-12-16-11-19(28)5-8-22(16)41-23/h3-8,11-12,14-15,21H,9-10,13H2,1-2H3,(H,32,36)/t21-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435050
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N- [[3-is...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(nc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H25F4N5O6S/c1-15(2)36-25(38)17(14-34(26(36)39)19-6-8-22(32-13-19)27(29,30)31)12-33-24(37)20-4-3-9-35(20)43(40,41)23-11-16-10-18(28)5-7-21(16)42-23/h5-8,10-11,13-15,20H,3-4,9,12H2,1-2H3,(H,33,37)/t20-/m0/s1
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n/an/a 10n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM434987
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N-[[3-eth...)
Show SMILES CCn1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H24F4N4O6S/c1-2-33-25(37)17(15-34(26(33)38)20-8-5-18(6-9-20)27(29,30)31)14-32-24(36)21-4-3-11-35(21)42(39,40)23-13-16-12-19(28)7-10-22(16)41-23/h5-10,12-13,15,21H,2-4,11,14H2,1H3,(H,32,36)/t21-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM434984
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[3-isopropyl-2...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H27F3N4O6S/c1-17(2)35-26(37)19(16-33(27(35)38)21-11-9-20(10-12-21)28(29,30)31)15-32-25(36)22-7-5-13-34(22)42(39,40)24-14-18-6-3-4-8-23(18)41-24/h3-4,6,8-12,14,16-17,22H,5,7,13,15H2,1-2H3,(H,32,36)/t22-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435054
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N- [[3-is...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cn2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H25F4N5O6S/c1-15(2)36-25(38)17(14-34(26(36)39)22-8-5-18(13-32-22)27(29,30)31)12-33-24(37)20-4-3-9-35(20)43(40,41)23-11-16-10-19(28)6-7-21(16)42-23/h5-8,10-11,13-15,20H,3-4,9,12H2,1-2H3,(H,33,37)/t20-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435043
PNG
((2S)-1-fro[3,2-c]pyridin-2-ylsulfonyl-N-[[3- isopr...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cnccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H26F3N5O6S/c1-16(2)35-25(37)18(15-33(26(35)38)20-7-5-19(6-8-20)27(28,29)30)14-32-24(36)21-4-3-11-34(21)42(39,40)23-12-17-13-31-10-9-22(17)41-23/h5-10,12-13,15-16,21H,3-4,11,14H2,1-2H3,(H,32,36)/t21-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435025
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N-[[3- me...)
Show SMILES Cn1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C26H22F4N4O6S/c1-32-24(36)16(14-33(25(32)37)19-7-4-17(5-8-19)26(28,29)30)13-31-23(35)20-3-2-10-34(20)41(38,39)22-12-15-11-18(27)6-9-21(15)40-22/h4-9,11-12,14,20H,2-3,10,13H2,1H3,(H,31,35)/t20-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435063
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N- [[1-is...)
Show SMILES CC(C)n1cc(cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)c1=O)-c1ccc(cn1)C(F)(F)F
Show InChI InChI=1S/C28H26F4N4O5S/c1-16(2)35-15-19(22-7-5-20(14-33-22)28(30,31)32)10-18(27(35)38)13-34-26(37)23-4-3-9-36(23)42(39,40)25-12-17-11-21(29)6-8-24(17)41-25/h5-8,10-12,14-16,23H,3-4,9,13H2,1-2H3,(H,34,37)/t23-/m0/s1
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n/an/a 23n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435061
PNG
((2S)-N-[[1-(4-chlorophenyl)-3-isopropyl-2,4- diox...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C27H26ClFN4O6S/c1-16(2)33-26(35)18(15-31(27(33)36)21-8-5-19(28)6-9-21)14-30-25(34)22-4-3-11-32(22)40(37,38)24-13-17-12-20(29)7-10-23(17)39-24/h5-10,12-13,15-16,22H,3-4,11,14H2,1-2H3,(H,30,34)/t22-/m0/s1
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n/an/a 24n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435030
PNG
((2S)-1-(4-fluorobenzofuran-2-yl)sulfonyl-N-[[3- is...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3c(F)cccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H26F4N4O6S/c1-16(2)36-26(38)17(15-34(27(36)39)19-10-8-18(9-11-19)28(30,31)32)14-33-25(37)22-6-4-12-35(22)43(40,41)24-13-20-21(29)5-3-7-23(20)42-24/h3,5,7-11,13,15-16,22H,4,6,12,14H2,1-2H3,(H,33,37)/t22-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM434985
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[3-ethyl-2,4- ...)
Show SMILES CCn1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H25F3N4O6S/c1-2-32-25(36)18(16-33(26(32)37)20-11-9-19(10-12-20)27(28,29)30)15-31-24(35)21-7-5-13-34(21)41(38,39)23-14-17-6-3-4-8-22(17)40-23/h3-4,6,8-12,14,16,21H,2,5,7,13,15H2,1H3,(H,31,35)/t21-/m0/s1
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n/an/a 26n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435033
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[1-isopropyl- ...)
Show SMILES CC(C)n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)cc(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C29H28F3N3O5S/c1-18(2)34-17-19(14-23(28(34)37)20-9-11-22(12-10-20)29(30,31)32)16-33-27(36)24-7-5-13-35(24)41(38,39)26-15-21-6-3-4-8-25(21)40-26/h3-4,6,8-12,14-15,17-18,24H,5,7,13,16H2,1-2H3,(H,33,36)/t24-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435049
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[3-isopropyl- ...)
Show SMILES CC(C)N1C(=O)C(C=C(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)C1=O)c1ccc(nc1)C(F)(F)F
Show InChI InChI=1S/C28H27F3N4O6S/c1-16(2)35-26(37)19(12-20(27(35)38)18-9-10-23(32-14-18)28(29,30)31)15-33-25(36)21-7-5-11-34(21)42(39,40)24-13-17-6-3-4-8-22(17)41-24/h3-4,6,8-10,12-14,16,20-21H,5,7,11,15H2,1-2H3,(H,33,36)/t20?,21-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435057
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N- [[1-is...)
Show SMILES CC(C)n1cc(cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)c1=O)-c1ccc(nc1)C(F)(F)F
Show InChI InChI=1S/C28H26F4N4O5S/c1-16(2)35-15-20(17-5-8-24(33-13-17)28(30,31)32)10-19(27(35)38)14-34-26(37)22-4-3-9-36(22)42(39,40)25-12-18-11-21(29)6-7-23(18)41-25/h5-8,10-13,15-16,22H,3-4,9,14H2,1-2H3,(H,34,37)/t22-/m0/s1
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n/an/a 31n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435031
PNG
((2S)-1-[(5-chloro-2-thienyl)sulfonyl]-N-[[3- isopr...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2ccc(Cl)s2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C24H24ClF3N4O5S2/c1-14(2)32-22(34)15(13-30(23(32)35)17-7-5-16(6-8-17)24(26,27)28)12-29-21(33)18-4-3-11-31(18)39(36,37)20-10-9-19(25)38-20/h5-10,13-14,18H,3-4,11-12H2,1-2H3,(H,29,33)/t18-/m0/s1
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n/an/a 33n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435044
PNG
((2S)-2-[(5-fluorobenzofuran-2-yl)sulfonylamino]-N-...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@H](C)NS(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C26H24F4N4O6S/c1-14(2)34-24(36)17(13-33(25(34)37)20-7-4-18(5-8-20)26(28,29)30)12-31-23(35)15(3)32-41(38,39)22-11-16-10-19(27)6-9-21(16)40-22/h4-11,13-15,32H,12H2,1-3H3,(H,31,35)/t15-/m0/s1
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n/an/a 42n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435053
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[3- isopropyl-...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)cn(-c2ccc(cn2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H26F3N5O6S/c1-16(2)35-25(37)18(15-33(26(35)38)22-10-9-19(14-31-22)27(28,29)30)13-32-24(36)20-7-5-11-34(20)42(39,40)23-12-17-6-3-4-8-21(17)41-23/h3-4,6,8-10,12,14-16,20H,5,7,11,13H2,1-2H3,(H,32,36)/t20-/m0/s1
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n/an/a 44n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435069
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N- [[1-is...)
Show SMILES CC(C)n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cc(-c2ccc(nc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H26F4N4O5S/c1-16(2)35-15-17(10-21(27(35)38)18-5-8-24(33-14-18)28(30,31)32)13-34-26(37)22-4-3-9-36(22)42(39,40)25-12-19-11-20(29)6-7-23(19)41-25/h5-8,10-12,14-16,22H,3-4,9,13H2,1-2H3,(H,34,37)/t22-/m0/s1
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n/an/a 45n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435037
PNG
((2S)-4,4-difluoro-1-(5-fluorobenzofuran-2- yl)sulf...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CC(F)(F)CN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H24F6N4O6S/c1-15(2)38-25(40)17(13-36(26(38)41)20-6-3-18(4-7-20)28(32,33)34)12-35-24(39)21-11-27(30,31)14-37(21)45(42,43)23-10-16-9-19(29)5-8-22(16)44-23/h3-10,13,15,21H,11-12,14H2,1-2H3,(H,35,39)/t21-/m0/s1
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n/an/a 46n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435040
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N-[[1- is...)
Show SMILES CC(C)n1cc(cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)c1=O)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C29H27F4N3O5S/c1-17(2)35-16-21(18-5-7-22(8-6-18)29(31,32)33)12-20(28(35)38)15-34-27(37)24-4-3-11-36(24)42(39,40)26-14-19-13-23(30)9-10-25(19)41-26/h5-10,12-14,16-17,24H,3-4,11,15H2,1-2H3,(H,34,37)/t24-/m0/s1
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n/an/a 49n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435039
PNG
((2S)-1-(benzothiophen-2-ylsulfonyl)-N-[[3- isoprop...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3s2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H27F3N4O5S2/c1-17(2)35-26(37)19(16-33(27(35)38)21-11-9-20(10-12-21)28(29,30)31)15-32-25(36)22-7-5-13-34(22)42(39,40)24-14-18-6-3-4-8-23(18)41-24/h3-4,6,8-12,14,16-17,22H,5,7,13,15H2,1-2H3,(H,32,36)/t22-/m0/s1
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n/an/a 56n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435042
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N-[[6- ox...)
Show SMILES Fc1ccc2oc(cc2c1)S(=O)(=O)N1CCC[C@H]1C(=O)NCc1ccc(=O)n(c1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C26H21F4N3O5S/c27-19-6-9-22-17(12-19)13-24(38-22)39(36,37)33-11-1-2-21(33)25(35)31-14-16-3-10-23(34)32(15-16)20-7-4-18(5-8-20)26(28,29)30/h3-10,12-13,15,21H,1-2,11,14H2,(H,31,35)/t21-/m0/s1
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n/an/a 60n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435028
PNG
((2S,3S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-3- hyd...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2[C@@H](O)CCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H26F4N4O7S/c1-15(2)36-26(39)17(14-34(27(36)40)20-6-3-18(4-7-20)28(30,31)32)13-33-25(38)24-21(37)9-10-35(24)44(41,42)23-12-16-11-19(29)5-8-22(16)43-23/h3-8,11-12,14-15,21,24,37H,9-10,13H2,1-2H3,(H,33,38)/t21-,24-/m0/s1
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n/an/a 64n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435035
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[1-isopropyl- ...)
Show SMILES CC(C)n1cc(cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)c1=O)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C29H28F3N3O5S/c1-18(2)34-17-22(19-9-11-23(12-10-19)29(30,31)32)14-21(28(34)37)16-33-27(36)24-7-5-13-35(24)41(38,39)26-15-20-6-3-4-8-25(20)40-26/h3-4,6,8-12,14-15,17-18,24H,5,7,13,16H2,1-2H3,(H,33,36)/t24-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435062
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[1- isopropyl-...)
Show SMILES CC(C)n1cc(cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)c1=O)-c1ccc(cn1)C(F)(F)F
Show InChI InChI=1S/C28H27F3N4O5S/c1-17(2)34-16-20(22-10-9-21(15-32-22)28(29,30)31)12-19(27(34)37)14-33-26(36)23-7-5-11-35(23)41(38,39)25-13-18-6-3-4-8-24(18)40-25/h3-4,6,8-10,12-13,15-17,23H,5,7,11,14H2,1-2H3,(H,33,36)/t23-/m0/s1
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n/an/a 79n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435071
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N- [[1-is...)
Show SMILES CC(C)n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cc(-c2ccc(cn2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H26F4N4O5S/c1-16(2)35-15-17(10-21(27(35)38)22-7-5-19(14-33-22)28(30,31)32)13-34-26(37)23-4-3-9-36(23)42(39,40)25-12-18-11-20(29)6-8-24(18)41-25/h5-8,10-12,14-16,23H,3-4,9,13H2,1-2H3,(H,34,37)/t23-/m0/s1
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n/an/a 81n/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435060
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[1-(4- chlorop...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)cn(-c2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C27H27ClN4O6S/c1-17(2)32-26(34)19(16-30(27(32)35)21-11-9-20(28)10-12-21)15-29-25(33)22-7-5-13-31(22)39(36,37)24-14-18-6-3-4-8-23(18)38-24/h3-4,6,8-12,14,16-17,22H,5,7,13,15H2,1-2H3,(H,29,33)/t22-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435065
PNG
((2S)-1-(4-fluorobenzofuran-2-yl)sulfonyl-N- [[1-is...)
Show SMILES CC(C)n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3c(F)cccc3o2)cc(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C29H27F4N3O5S/c1-17(2)35-16-18(13-21(28(35)38)19-8-10-20(11-9-19)29(31,32)33)15-34-27(37)24-6-4-12-36(24)42(39,40)26-14-22-23(30)5-3-7-25(22)41-26/h3,5,7-11,13-14,16-17,24H,4,6,12,15H2,1-2H3,(H,34,37)/t24-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435047
PNG
((2S)-1-fro[3,2-c]pyridin-2-ylsulfonyl-N-[[1- isopr...)
Show SMILES CC(C)N1C(=O)C(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cnccc3o2)=CC(c2ccc(cc2)C(F)(F)F)=[C]1=O
Show InChI InChI=1S/C28H26F3N4O6S/c1-16(2)35-26(37)19(12-21(27(35)38)17-5-7-20(8-6-17)28(29,30)31)15-33-25(36)22-4-3-11-34(22)42(39,40)24-13-18-14-32-10-9-23(18)41-24/h5-10,12-14,16,22H,3-4,11,15H2,1-2H3,(H,33,36)/t22-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435066
PNG
((2S)-1-fro[3,2-c]pyridin-2-ylsulfonyl-N-[[1- isopr...)
Show SMILES CC(C)n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cnccc3o2)cc(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H27F3N4O5S/c1-17(2)34-16-18(12-22(27(34)37)19-5-7-21(8-6-19)28(29,30)31)14-33-26(36)23-4-3-11-35(23)41(38,39)25-13-20-15-32-10-9-24(20)40-25/h5-10,12-13,15-17,23H,3-4,11,14H2,1-2H3,(H,33,36)/t23-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435059
PNG
((2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N- [[1-(4...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(F)cc2)c1=O
Show InChI InChI=1S/C27H26F2N4O6S/c1-16(2)33-26(35)18(15-31(27(33)36)21-8-5-19(28)6-9-21)14-30-25(34)22-4-3-11-32(22)40(37,38)24-13-17-12-20(29)7-10-23(17)39-24/h5-10,12-13,15-16,22H,3-4,11,14H2,1-2H3,(H,30,34)/t22-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435070
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[1- isopropyl-...)
Show SMILES CC(C)n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)cc(-c2ccc(cn2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H27F3N4O5S/c1-17(2)34-16-18(12-21(27(34)37)22-10-9-20(15-32-22)28(29,30)31)14-33-26(36)23-7-5-11-35(23)41(38,39)25-13-19-6-3-4-8-24(19)40-25/h3-4,6,8-10,12-13,15-17,23H,5,7,11,14H2,1-2H3,(H,33,36)/t23-/m0/s1
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EA Pharma Co., Ltd.

US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435032
PNG
((2S)-1-(4-fluorophenyl)sulfonyl-N-[[3-isopropyl- 2...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2ccc(F)cc2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C26H26F4N4O5S/c1-16(2)34-24(36)17(15-32(25(34)37)20-9-5-18(6-10-20)26(28,29)30)14-31-23(35)22-4-3-13-33(22)40(38,39)21-11-7-19(27)8-12-21/h5-12,15-16,22H,3-4,13-14H2,1-2H3,(H,31,35)/t22-/m0/s1
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US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435029
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[2,4-dioxo-3- ...)
Show SMILES FC(F)(F)c1ccc(cc1)-n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)c(=O)n(C2CCOCC2)c1=O
Show InChI InChI=1S/C30H29F3N4O7S/c31-30(32,33)21-7-9-22(10-8-21)35-18-20(28(39)37(29(35)40)23-11-14-43-15-12-23)17-34-27(38)24-5-3-13-36(24)45(41,42)26-16-19-4-1-2-6-25(19)44-26/h1-2,4,6-10,16,18,23-24H,3,5,11-15,17H2,(H,34,38)/t24-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435034
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[6-oxo-1-[4- (...)
Show SMILES FC(F)(F)c1ccc(cc1)-n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)ccc1=O
Show InChI InChI=1S/C26H22F3N3O5S/c27-26(28,29)19-8-10-20(11-9-19)31-16-17(7-12-23(31)33)15-30-25(34)21-5-3-13-32(21)38(35,36)24-14-18-4-1-2-6-22(18)37-24/h1-2,4,6-12,14,16,21H,3,5,13,15H2,(H,30,34)/t21-/m0/s1
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US Patent


Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435055
PNG
((2S,3S)-1-(5-fluorobenzofuran-2-yl)sulfonyl- 3-hyd...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2[C@@H](O)CCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cn2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H25F4N5O7S/c1-14(2)36-25(39)16(13-34(26(36)40)21-6-3-17(12-32-21)27(29,30)31)11-33-24(38)23-19(37)7-8-35(23)44(41,42)22-10-15-9-18(28)4-5-20(15)43-22/h3-6,9-10,12-14,19,23,37H,7-8,11H2,1-2H3,(H,33,38)/t19-,23-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435048
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[1-isopropyl- ...)
Show SMILES CC(C)n1cc(cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)c1=O)-c1ccc(nc1)C(F)(F)F
Show InChI InChI=1S/C28H27F3N4O5S/c1-17(2)34-16-21(19-9-10-24(32-14-19)28(29,30)31)12-20(27(34)37)15-33-26(36)22-7-5-11-35(22)41(38,39)25-13-18-6-3-4-8-23(18)40-25/h3-4,6,8-10,12-14,16-17,22H,5,7,11,15H2,1-2H3,(H,33,36)/t22-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435056
PNG
((2S)-1-fro[3,2-c]pyridin-2-ylsulfonyl-N-[[3- isopr...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cnccc3o2)cn(-c2ccc(cn2)C(F)(F)F)c1=O
Show InChI InChI=1S/C26H25F3N6O6S/c1-15(2)35-24(37)17(14-33(25(35)38)21-6-5-18(13-31-21)26(27,28)29)12-32-23(36)19-4-3-9-34(19)42(39,40)22-10-16-11-30-8-7-20(16)41-22/h5-8,10-11,13-15,19H,3-4,9,12H2,1-2H3,(H,32,36)/t19-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435068
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[1- isopropyl-...)
Show SMILES CC(C)n1cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)cc(-c2ccc(nc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H27F3N4O5S/c1-17(2)34-16-18(12-21(27(34)37)20-9-10-24(32-15-20)28(29,30)31)14-33-26(36)22-7-5-11-35(22)41(38,39)25-13-19-6-3-4-8-23(19)40-25/h3-4,6,8-10,12-13,15-17,22H,5,7,11,14H2,1-2H3,(H,33,36)/t22-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435027
PNG
((2S,3S)-1-(benzofuran-2-ylsulfonyl)-3-hydroxy-N-[[...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2[C@@H](O)CCN2S(=O)(=O)c2cc3ccccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C28H27F3N4O7S/c1-16(2)35-26(38)18(15-33(27(35)39)20-9-7-19(8-10-20)28(29,30)31)14-32-25(37)24-21(36)11-12-34(24)43(40,41)23-13-17-5-3-4-6-22(17)42-23/h3-10,13,15-16,21,24,36H,11-12,14H2,1-2H3,(H,32,37)/t21-,24-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435067
PNG
((2S,3S)-1-(5-fluorobenzofuran-2-yl)sulfonyl- 3-hyd...)
Show SMILES CC(C)n1cc(CNC(=O)[C@@H]2[C@@H](O)CCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cc(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C29H27F4N3O6S/c1-16(2)35-15-17(11-22(28(35)39)18-3-5-20(6-4-18)29(31,32)33)14-34-27(38)26-23(37)9-10-36(26)43(40,41)25-13-19-12-21(30)7-8-24(19)42-25/h3-8,11-13,15-16,23,26,37H,9-10,14H2,1-2H3,(H,34,38)/t23-,26-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435058
PNG
((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[1-(4- fluorop...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)cn(-c2ccc(F)cc2)c1=O
Show InChI InChI=1S/C27H27FN4O6S/c1-17(2)32-26(34)19(16-30(27(32)35)21-11-9-20(28)10-12-21)15-29-25(33)22-7-5-13-31(22)39(36,37)24-14-18-6-3-4-8-23(18)38-24/h3-4,6,8-12,14,16-17,22H,5,7,13,15H2,1-2H3,(H,29,33)/t22-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435046
PNG
(1-[(5-fluorobenzofuran-2-yl)sulfonylamino]-N-[[1- ...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)C2(CC2)NS(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H24F4N4O6S/c1-15(2)35-23(36)17(14-34(25(35)38)20-6-3-18(4-7-20)27(29,30)31)13-32-24(37)26(9-10-26)33-42(39,40)22-12-16-11-19(28)5-8-21(16)41-22/h3-8,11-12,14-15,33H,9-10,13H2,1-2H3,(H,32,37)
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435051
PNG
((2S,3S)-1-(5-fluorobenzofuran-2-yl)sulfonyl- 3-hyd...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2[C@@H](O)CCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(nc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C27H25F4N5O7S/c1-14(2)36-25(39)16(13-34(26(36)40)18-4-6-21(32-12-18)27(29,30)31)11-33-24(38)23-19(37)7-8-35(23)44(41,42)22-10-15-9-17(28)3-5-20(15)43-22/h3-6,9-10,12-14,19,23,37H,7-8,11H2,1-2H3,(H,33,38)/t19-,23-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435045
PNG
((2S)-N-[[3-isopropyl-2,4-dioxo-1-[4- (trifluoromet...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(C)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C29H29F3N4O6S/c1-17(2)36-27(38)20(16-34(28(36)39)22-9-7-21(8-10-22)29(30,31)32)15-33-26(37)23-5-4-12-35(23)43(40,41)25-14-19-13-18(3)6-11-24(19)42-25/h6-11,13-14,16-17,23H,4-5,12,15H2,1-3H3,(H,33,37)/t23-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435064
PNG
((2S)-1-(4-fluorobenzofuran-2-yl)sulfonyl-N- [[1-is...)
Show SMILES CC(C)n1cc(cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3c(F)cccc3o2)c1=O)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C29H27F4N3O5S/c1-17(2)35-16-20(18-8-10-21(11-9-18)29(31,32)33)13-19(28(35)38)15-34-27(37)24-6-4-12-36(24)42(39,40)26-14-22-23(30)5-3-7-25(22)41-26/h3,5,7-11,13-14,16-17,24H,4,6,12,15H2,1-2H3,(H,34,37)/t24-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435026
PNG
((2S)-2-[(5-fluorobenzofuran-2-yl)sulfonylamino]-N-...)
Show SMILES C[C@H](NS(=O)(=O)c1cc2cc(F)ccc2o1)C(=O)NCc1cn(-c2ccc(cc2)C(F)(F)F)c(=O)n(C)c1=O
Show InChI InChI=1S/C24H20F4N4O6S/c1-13(30-39(36,37)20-10-14-9-17(25)5-8-19(14)38-20)21(33)29-11-15-12-32(23(35)31(2)22(15)34)18-6-3-16(4-7-18)24(26,27)28/h3-10,12-13,30H,11H2,1-2H3,(H,29,33)/t13-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM435052
PNG
((2S)-1-fro[3,2-c]pyridin-2-ylsulfonyl-N-[[3- isopr...)
Show SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cnccc3o2)cn(-c2ccc(nc2)C(F)(F)F)c1=O
Show InChI InChI=1S/C26H25F3N6O6S/c1-15(2)35-24(37)17(14-33(25(35)38)18-5-6-21(31-13-18)26(27,28)29)12-32-23(36)19-4-3-9-34(19)42(39,40)22-10-16-11-30-8-7-20(16)41-22/h5-8,10-11,13-15,19H,3-4,9,12H2,1-2H3,(H,32,36)/t19-/m0/s1
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Assay Description
Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...


US Patent US10584116 (2020)


BindingDB Entry DOI: 10.7270/Q23B62HT
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Ligand-Target Pair
* indicates data uncertainty>20%