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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OTU domain-containing protein 7B (Human) | BDBM436072 ((R)-1-cyano-3-fluoro-N-(1-phenyl-1H-pyrazol-4-yl)p...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436054 (N-(benzo[d]thiazol-6-yl)-1-cyano- 3-fluoropyrrolid...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436097 (N-(6-(1H-pyrazol-5-yl)imidazo[1,2-a]pyridin-2-yl)-...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436091 ((R)-1-cyano-3-fluoro-N-(5-(3-(methylcarbamoyl)phen...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436090 (1-cyano-3-fluoro-N-(5-(3-(methylcarbamoyl)phenyl) ...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436085 ((R)—N-(5-(1H-indazol-7-yl)thiazol-2-yl)-1-cya...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436064 ((R)-1-cyano-3-fluoro-N-(5-phenylthiazol-2-yl) pyrr...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436066 (1-cyano-3-fluoro-N-(5-phenylisoxazol-3-yl)pyrrolid...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436093 (N-(3-(3-(1H-imidazol-1-yl)phenyl)isoxazol-5-yl)-1-...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436083 (N-(5-(1H-indazol-4-yl) thiazol-2-yl)-1-cyano-3-flu...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436092 (N-(5-(3-(1H-imidazol-1-yl)phenyl)thiazol-2-yl)-1-c...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436088 ((R)-1-cyano-3-fluoro-N-(3-phenylisoxazol-5-yl)pyrr...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436089 (N-(5-(3-carbamoylphenyl)thiazol-2-yl)-1-cyano-3-fl...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436096 ((R)—N-(3-(3-(1H-imidazol-1-yl)phenyl)isoxazol...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436063 (1-cyano-3-fluoro-N-(5-phenylthiazol-2-yl) pyrrolid...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436087 (1-cyano-3-fluoro-N-(3-phenylisoxazol-5-yl)pyrrolid...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436068 (1-cyano-3-fluoro-N-(1-phenyl-1H-imidazol-4-yl)pyrr...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436062 (1-cyano-3-fluoro-N-(3- phenoxyphenyl)pyrrolidine-3...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436059 (1-cyano-3-fluoro-N-(3-(2- methylthiazol-4- yl)phen...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436077 (N-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)-1-cyan...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436098 (1-cyano-3-fluoro-N-(6-(3-(methylcarbamoyl)phenyl)b...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436075 ((R)—N-(1-benzyl-1H-pyrazol-4-yl)-1-cyano-3-fl...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436073 ((R)-1-cyano-N-(1-(4-cyanophenyl)-1H-imidazol-4-yl)...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436053 (1-cyano-3-fluoro-N-(4- phenylthiazol-2-yl)pyrrolid...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436082 (1-cyano-3-fluoro-N-(6-phenylbenzo[d]thiazol-2-yl)p...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436051 (N-(4-chloro-3-(trifluoromethyl)phenyl)-1-cyano-3-f...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436058 (1-cyano-3-fluoro-N-(quinolin-6- yl)pyrrolidine-3-c...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436069 ((S)-1-cyano-3-fluoro-N-(1-phenyl-1H-pyrazol-4-yl)p...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| OTU domain-containing protein 7B (Human) | BDBM436057 (1-cyano-3-fluoro-N-(quinolin-3- yl)pyrrolidine-3-c...) | PDB UniProtKB/SwissProt GoogleScholar | UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MISSION THERAPEUTICS LIMITED US Patent | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | US Patent US10590075 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
