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Patent code US10590075

Compile Data Set for Download or QSAR
Found 29 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
OTU domain-containing protein 7B


(Human)
BDBM436072
PNG
((R)-1-cyano-3-fluoro-N-(1-phenyl-1H-pyrazol-4-yl)p...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)Nc1cnn(c1)-c1ccccc1
Show InChI InChI=1S/C15H14FN5O/c16-15(6-7-20(10-15)11-17)14(22)19-12-8-18-21(9-12)13-4-2-1-3-5-13/h1-5,8-9H,6-7,10H2,(H,19,22)/t15-/m1/s1
PDB

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US Patent
n/an/a<100n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436054
PNG
(N-(benzo[d]thiazol-6-yl)-1-cyano- 3-fluoropyrrolid...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1ccc2ncsc2c1
Show InChI InChI=1S/C13H11FN4OS/c14-13(3-4-18(6-13)7-15)12(19)17-9-1-2-10-11(5-9)20-8-16-10/h1-2,5,8H,3-4,6H2,(H,17,19)
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436097
PNG
(N-(6-(1H-pyrazol-5-yl)imidazo[1,2-a]pyridin-2-yl)-...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1cn2cc(ccc2n1)-c1ccn[nH]1
PDB

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436091
PNG
((R)-1-cyano-3-fluoro-N-(5-(3-(methylcarbamoyl)phen...)
Show SMILES CNC(=O)c1cccc(c1)-c1cnc(NC(=O)[C@@]2(F)CCN(C2)C#N)s1
Show InChI InChI=1S/C17H16FN5O2S/c1-20-14(24)12-4-2-3-11(7-12)13-8-21-16(26-13)22-15(25)17(18)5-6-23(9-17)10-19/h2-4,7-8H,5-6,9H2,1H3,(H,20,24)(H,21,22,25)/t17-/m1/s1
PDB

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436090
PNG
(1-cyano-3-fluoro-N-(5-(3-(methylcarbamoyl)phenyl) ...)
Show SMILES CNC(=O)c1cccc(c1)-c1cnc(NC(=O)C2(F)CCN(C2)C#N)s1
Show InChI InChI=1S/C17H16FN5O2S/c1-20-14(24)12-4-2-3-11(7-12)13-8-21-16(26-13)22-15(25)17(18)5-6-23(9-17)10-19/h2-4,7-8H,5-6,9H2,1H3,(H,20,24)(H,21,22,25)
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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436085
PNG
((R)—N-(5-(1H-indazol-7-yl)thiazol-2-yl)-1-cya...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)Nc1ncc(s1)-c1cccc2[nH]ncc12
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436064
PNG
((R)-1-cyano-3-fluoro-N-(5-phenylthiazol-2-yl) pyrr...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)Nc1ncc(s1)-c1ccccc1
Show InChI InChI=1S/C15H13FN4OS/c16-15(6-7-20(9-15)10-17)13(21)19-14-18-8-12(22-14)11-4-2-1-3-5-11/h1-5,8H,6-7,9H2,(H,18,19,21)/t15-/m1/s1
PDB

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436066
PNG
(1-cyano-3-fluoro-N-(5-phenylisoxazol-3-yl)pyrrolid...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1cc(on1)-c1ccccc1
Show InChI InChI=1S/C15H13FN4O2/c16-15(6-7-20(9-15)10-17)14(21)18-13-8-12(22-19-13)11-4-2-1-3-5-11/h1-5,8H,6-7,9H2,(H,18,19,21)
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436093
PNG
(N-(3-(3-(1H-imidazol-1-yl)phenyl)isoxazol-5-yl)-1-...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1cc(no1)-c1cccc(c1)-n1ccnc1
Show InChI InChI=1S/C18H15FN6O2/c19-18(4-6-24(10-18)11-20)17(26)22-16-9-15(23-27-16)13-2-1-3-14(8-13)25-7-5-21-12-25/h1-3,5,7-9,12H,4,6,10H2,(H,22,26)
PDB

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436083
PNG
(N-(5-(1H-indazol-4-yl) thiazol-2-yl)-1-cyano-3-flu...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1ncc(s1)-c1cccc2[nH]ncc12
PDB

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436092
PNG
(N-(5-(3-(1H-imidazol-1-yl)phenyl)thiazol-2-yl)-1-c...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1ncc(s1)-c1cccc(c1)-n1ccnc1
Show InChI InChI=1S/C18H15FN6OS/c19-18(4-6-24(10-18)11-20)16(26)23-17-22-9-15(27-17)13-2-1-3-14(8-13)25-7-5-21-12-25/h1-3,5,7-9,12H,4,6,10H2,(H,22,23,26)
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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436088
PNG
((R)-1-cyano-3-fluoro-N-(3-phenylisoxazol-5-yl)pyrr...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)Nc1cc(no1)-c1ccccc1
Show InChI InChI=1S/C15H13FN4O2/c16-15(6-7-20(9-15)10-17)14(21)18-13-8-12(19-22-13)11-4-2-1-3-5-11/h1-5,8H,6-7,9H2,(H,18,21)/t15-/m1/s1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436089
PNG
(N-(5-(3-carbamoylphenyl)thiazol-2-yl)-1-cyano-3-fl...)
Show SMILES NC(=O)c1cccc(c1)-c1cnc(NC(=O)C2(F)CCN(C2)C#N)s1
Show InChI InChI=1S/C16H14FN5O2S/c17-16(4-5-22(8-16)9-18)14(24)21-15-20-7-12(25-15)10-2-1-3-11(6-10)13(19)23/h1-3,6-7H,4-5,8H2,(H2,19,23)(H,20,21,24)
PDB

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436096
PNG
((R)—N-(3-(3-(1H-imidazol-1-yl)phenyl)isoxazol...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)Nc1cc(no1)-c1cccc(c1)-n1ccnc1
Show InChI InChI=1S/C18H15FN6O2/c19-18(4-6-24(10-18)11-20)17(26)22-16-9-15(23-27-16)13-2-1-3-14(8-13)25-7-5-21-12-25/h1-3,5,7-9,12H,4,6,10H2,(H,22,26)/t18-/m1/s1
PDB

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436063
PNG
(1-cyano-3-fluoro-N-(5-phenylthiazol-2-yl) pyrrolid...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1ncc(s1)-c1ccccc1
Show InChI InChI=1S/C15H13FN4OS/c16-15(6-7-20(9-15)10-17)13(21)19-14-18-8-12(22-14)11-4-2-1-3-5-11/h1-5,8H,6-7,9H2,(H,18,19,21)
PDB

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436087
PNG
(1-cyano-3-fluoro-N-(3-phenylisoxazol-5-yl)pyrrolid...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1cc(no1)-c1ccccc1
Show InChI InChI=1S/C15H13FN4O2/c16-15(6-7-20(9-15)10-17)14(21)18-13-8-12(19-22-13)11-4-2-1-3-5-11/h1-5,8H,6-7,9H2,(H,18,21)
PDB

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US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436068
PNG
(1-cyano-3-fluoro-N-(1-phenyl-1H-imidazol-4-yl)pyrr...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C15H14FN5O/c16-15(6-7-20(9-15)10-17)14(22)19-13-8-21(11-18-13)12-4-2-1-3-5-12/h1-5,8,11H,6-7,9H2,(H,19,22)
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436062
PNG
(1-cyano-3-fluoro-N-(3- phenoxyphenyl)pyrrolidine-3...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C18H16FN3O2/c19-18(9-10-22(12-18)13-20)17(23)21-14-5-4-8-16(11-14)24-15-6-2-1-3-7-15/h1-8,11H,9-10,12H2,(H,21,23)
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436059
PNG
(1-cyano-3-fluoro-N-(3-(2- methylthiazol-4- yl)phen...)
Show SMILES Cc1nc(cs1)-c1cccc(NC(=O)C2(F)CCN(C2)C#N)c1
Show InChI InChI=1S/C16H15FN4OS/c1-11-19-14(8-23-11)12-3-2-4-13(7-12)20-15(22)16(17)5-6-21(9-16)10-18/h2-4,7-8H,5-6,9H2,1H3,(H,20,22)
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436077
PNG
(N-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)-1-cyan...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1nc2ccc(cc2s1)-c1cn[nH]c1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436098
PNG
(1-cyano-3-fluoro-N-(6-(3-(methylcarbamoyl)phenyl)b...)
Show SMILES CNC(=O)c1cccc(c1)-c1ccc2nc(NC(=O)C3(F)CCN(C3)C#N)sc2c1
Show InChI InChI=1S/C21H18FN5O2S/c1-24-18(28)15-4-2-3-13(9-15)14-5-6-16-17(10-14)30-20(25-16)26-19(29)21(22)7-8-27(11-21)12-23/h2-6,9-10H,7-8,11H2,1H3,(H,24,28)(H,25,26,29)
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US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436075
PNG
((R)—N-(1-benzyl-1H-pyrazol-4-yl)-1-cyano-3-fl...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)Nc1cnn(Cc2ccccc2)c1
Show InChI InChI=1S/C16H16FN5O/c17-16(6-7-21(11-16)12-18)15(23)20-14-8-19-22(10-14)9-13-4-2-1-3-5-13/h1-5,8,10H,6-7,9,11H2,(H,20,23)/t16-/m1/s1
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436073
PNG
((R)-1-cyano-N-(1-(4-cyanophenyl)-1H-imidazol-4-yl)...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)Nc1cn(cn1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H13FN6O/c17-16(5-6-22(9-16)10-19)15(24)21-14-8-23(11-20-14)13-3-1-12(7-18)2-4-13/h1-4,8,11H,5-6,9H2,(H,21,24)/t16-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436053
PNG
(1-cyano-3-fluoro-N-(4- phenylthiazol-2-yl)pyrrolid...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C15H13FN4OS/c16-15(6-7-20(9-15)10-17)13(21)19-14-18-12(8-22-14)11-4-2-1-3-5-11/h1-5,8H,6-7,9H2,(H,18,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436082
PNG
(1-cyano-3-fluoro-N-(6-phenylbenzo[d]thiazol-2-yl)p...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1nc2ccc(cc2s1)-c1ccccc1
Show InChI InChI=1S/C19H15FN4OS/c20-19(8-9-24(11-19)12-21)17(25)23-18-22-15-7-6-14(10-16(15)26-18)13-4-2-1-3-5-13/h1-7,10H,8-9,11H2,(H,22,23,25)
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436051
PNG
(N-(4-chloro-3-(trifluoromethyl)phenyl)-1-cyano-3-f...)
Show SMILES FC(F)(F)c1cc(NC(=O)C2(F)CCN(C2)C#N)ccc1Cl
Show InChI InChI=1S/C13H10ClF4N3O/c14-10-2-1-8(5-9(10)13(16,17)18)20-11(22)12(15)3-4-21(6-12)7-19/h1-2,5H,3-4,6H2,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436058
PNG
(1-cyano-3-fluoro-N-(quinolin-6- yl)pyrrolidine-3-c...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1ccc2ncccc2c1
Show InChI InChI=1S/C15H13FN4O/c16-15(5-7-20(9-15)10-17)14(21)19-12-3-4-13-11(8-12)2-1-6-18-13/h1-4,6,8H,5,7,9H2,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436069
PNG
((S)-1-cyano-3-fluoro-N-(1-phenyl-1H-pyrazol-4-yl)p...)
Show SMILES F[C@]1(CCN(C1)C#N)C(=O)Nc1cnn(c1)-c1ccccc1
Show InChI InChI=1S/C15H14FN5O/c16-15(6-7-20(10-15)11-17)14(22)19-12-8-18-21(9-12)13-4-2-1-3-5-13/h1-5,8-9H,6-7,10H2,(H,19,22)/t15-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
OTU domain-containing protein 7B


(Human)
BDBM436057
PNG
(1-cyano-3-fluoro-N-(quinolin-3- yl)pyrrolidine-3-c...)
Show SMILES FC1(CCN(C1)C#N)C(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C15H13FN4O/c16-15(5-6-20(9-15)10-17)14(21)19-12-7-11-3-1-2-4-13(11)18-8-12/h1-4,7-8H,5-6,9H2,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10590075 (2020)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%