Affinity Data by Patent

Patent code US10590106

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
B-RAF V600E (Homo sapiens (Human))	BDBM436181 (US10590106, Compound C075) Show SMILES Show InChI	PDB GoogleScholar	UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE� Method as brie...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM436176 (US10590106, Compound C001) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM436180 (US10590106, Compound C003) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM436182 (US10590106, Compound C069) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
B-RAF V600E (Homo sapiens (Human))	BDBM436179 (US10590106, Compound C009) Show SMILES Show InChI	PDB GoogleScholar	UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE� Method as brie...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM436181 (US10590106, Compound C075) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
B-RAF V600E (Homo sapiens (Human))	BDBM436176 (US10590106, Compound C001) Show SMILES Show InChI	PDB GoogleScholar	UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE� Method as brie...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
B-RAF V600E (Homo sapiens (Human))	BDBM436180 (US10590106, Compound C003) Show SMILES Show InChI	PDB GoogleScholar	UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE� Method as brie...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM436179 (US10590106, Compound C009) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
B-RAF V600E (Homo sapiens (Human))	BDBM436174 (US10590109, Compound 1) Show SMILES Show InChI	PDB GoogleScholar	UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE� Method as brie...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
B-RAF V600E (Homo sapiens (Human))	BDBM436182 (US10590106, Compound C069) Show SMILES Show InChI	PDB GoogleScholar	UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE� Method as brie...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM436174 (US10590109, Compound 1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	UniChem	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
NeuPharma, Inc. US Patent					Assay Description Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...				US Patent US10590106 (2020)
NeuPharma, Inc. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%