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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300972 (5-((6S,8R)-1- fluoro-8- methyl-7- (2,2,2- trifluor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300961 (1-(3-Fluoropropyl)-N-(4-((6R,8R)-8-methyl-7-(2,2,2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.810 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM436275 (2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(5- ((1-(3- f...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 0.880 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300973 (2-fluoro-6- ((6S,8R)-1- fluoro-8- methyl-7- (2,2,2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300996 (2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(6- fluoro-5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300981 (6-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300974 (6-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300967 (5-Fluoro-6-((6S,8R)-1-fluoro-8-methyl-7-(2,2,2-tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300969 (BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300982 (N-(4-((6R,8R)- 7-(2,2- difluoroethyl)- 8-methyl- 6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300983 (N-(4-((6S,8R)- 7-(2,2- difluoroethyl)- 8-methyl- 6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300979 (N-(4-((6S,8R)- 7-(2,2- difluoroethyl)- 6,8-dimethy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300963 (2-fluoro-N-(1-(3-fluoropropyl)azetidin-3-yl)-6-((6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300964 (5-fluoro-N-(1-(3-fluoropropyl)azetidin-3-yl)-6-((6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300969 (BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300968 (N-(1-(3- fluoropropyl) azetidin-3-yl)- N-methyl-6-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300933 (N-(3,5-difluoro-4-((6S,8R)-8-methyl-7-(2,2,2-trifl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM301005 (5-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-6-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300955 (N-(4-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300969 (BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300992 (2,2-difluoro-3- ((6S,8R)-6-(5- ((1-(3- fluoropropy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300929 (3-((6S,8R)-6-(2,6-difluoro-4-((1-(3-fluoropropyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300969 (BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300945 (N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300975 (N-(2-fluoro-4- ((6R,8R)-8- methyl-7- (2,2,2- trifl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300953 (N-(4-((6S,8R)-7-(2,2-difluoropropyl)-8-methyl-6,7,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300984 (5-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300985 (6-((6S,8S)-7- (2,2- difluoroethyl)- 8- (difluorome...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300921 (6-((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-8-meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM301006 ((S)-6-(8,8- dimethyl-7- (2,2,2- trifluoroethyl)- 6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM301007 ((S)-6-(7-(2,2- difluoroethyl)- 8,8-dimethyl- 6,7,8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300945 (N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300980 (6-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300919 (N-(4-((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-8-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300976 (N-(1-(3- fluoropropyl) azetidin-3-yl)-5- ((6S,8R)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300959 (6-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8,9-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300977 (6-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300997 (6-((6S,8R)-7- (2-fluoro-2- methylpropyl)- 8-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM436274 (2,2-difluoro-3- ((6S,8R)-6-(4- ((1-(3- fluoropropy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300991 (6-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM301001 (1-(3- fluoropropyl)- N-(4-((6S,8R)- 7-(2- fluoropr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300999 (6-((6S,8R)-7- (2- fluoropropyl)- 8-methyl- 6,7,8,9...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300956 ((6S,8R)-7-(2,2-difluoroethyl)-6-(4-((1-(3-fluoropr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300962 (1-(3-fluoropropyl)-N-(3-methoxy-4-((6S,8R)-8-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300987 (N-(2-fluoro-4- ((6S,8R)-7-((1- fluorocyclo- propyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300998 (N-(4-((6S,8R)- 7-(2-fluoro-2- methylpropyl)- 8-met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300999 (6-((6S,8R)-7- (2- fluoropropyl)- 8-methyl- 6,7,8,9...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300924 (6-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300945 (N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300960 ((6S,8R)-7-(2,2-difluoroethyl)-6-(5-((1-(3-fluoropr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300950 (2,2-difluoro-3-((6S,8R)-6-(5-((1-(3-fluoropropyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300925 (N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300971 (N-(1-(3- fluoropropyl) azetidin-3-yl)-5- methoxy-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300993 (2,2-difluoro-3- ((6S,8R)-6-(3- fluoro-5-((1- (3- f...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300936 (N-(4-((6S,8R)-7-((3-(fluoromethyl)oxetan-3-yl)meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300990 (N-(4-((6S,8R)- 7-((1- fluorocyclo- propyl)methyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300989 (5-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300931 ((6S,8R)-7-((1-fluorocyclopropyl)methyl)-6-(4-((1-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300930 (N-(4-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM301003 (N-(1-(3- fluoropropyl) azetidin-3-yl)-6- ((6S,8R)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300945 (N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300978 (6-((6S,8R)-7- (2,2- difluoroethyl)- 6,8-dimethyl- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM436237 (Preparation of of individual diastereoisomers of 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300986 (N-(4-((6S,8R)- 7-((1- fluorocyclo- propyl)methyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300965 (2,2-Difluoro-3-((6S,8R)-6-(3-fluoro-5-((1-(3-fluor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300954 (N-(3-ethoxy-4-((6S,8R)-7-((1-fluorocyclopropyl)met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM301001 (1-(3- fluoropropyl)- N-(4-((6S,8R)- 7-(2- fluoropr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM436237 (Preparation of of individual diastereoisomers of 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300942 (BDBM436225 | N-(3,5-difluoro-4-((6S,8R)-7-((1-fluo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300952 (5-fluoro-6-((6S,8R)-7-((1-fluorocyclopropyl)methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300997 (6-((6S,8R)-7- (2-fluoro-2- methylpropyl)- 8-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300988 (5-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Melanin-concentrating hormone receptor 2/HERG (Homo sapiens (Human)) | BDBM300934 (5-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300986 (N-(4-((6S,8R)- 7-((1- fluorocyclo- propyl)methyl)-...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300979 (N-(4-((6S,8R)- 7-(2,2- difluoroethyl)- 6,8-dimethy...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300974 (6-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-5-...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300955 (N-(4-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300953 (N-(4-((6S,8R)-7-(2,2-difluoropropyl)-8-methyl-6,7,...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300975 (N-(2-fluoro-4- ((6R,8R)-8- methyl-7- (2,2,2- trifl...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300968 (N-(1-(3- fluoropropyl) azetidin-3-yl)- N-methyl-6-...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300962 (1-(3-fluoropropyl)-N-(3-methoxy-4-((6S,8R)-8-methy...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300961 (1-(3-Fluoropropyl)-N-(4-((6R,8R)-8-methyl-7-(2,2,2...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300976 (N-(1-(3- fluoropropyl) azetidin-3-yl)-5- ((6S,8R)-...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300983 (N-(4-((6S,8R)- 7-(2,2- difluoroethyl)- 8-methyl- 6...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300985 (6-((6S,8S)-7- (2,2- difluoroethyl)- 8- (difluorome...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300930 (N-(4-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-me...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300919 (N-(4-((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-8-m...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM436274 (2,2-difluoro-3- ((6S,8R)-6-(4- ((1-(3- fluoropropy...) | PDB GoogleScholar | UniChem | US Patent | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM301007 ((S)-6-(7-(2,2- difluoroethyl)- 8,8-dimethyl- 6,7,8...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300998 (N-(4-((6S,8R)- 7-(2-fluoro-2- methylpropyl)- 8-met...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300984 (5-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300929 (3-((6S,8R)-6-(2,6-difluoro-4-((1-(3-fluoropropyl)a...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300997 (6-((6S,8R)-7- (2-fluoro-2- methylpropyl)- 8-methyl...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300969 (BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300973 (2-fluoro-6- ((6S,8R)-1- fluoro-8- methyl-7- (2,2,2...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM301001 (1-(3- fluoropropyl)- N-(4-((6S,8R)- 7-(2- fluoropr...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300967 (5-Fluoro-6-((6S,8R)-1-fluoro-8-methyl-7-(2,2,2-tri...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300991 (6-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- ...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300925 (N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300972 (5-((6S,8R)-1- fluoro-8- methyl-7- (2,2,2- trifluor...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300971 (N-(1-(3- fluoropropyl) azetidin-3-yl)-5- methoxy-6...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300969 (BDBM300970 | N-(1-(3- fluoropropyl) azetidin-3-yl)...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM301003 (N-(1-(3- fluoropropyl) azetidin-3-yl)-6- ((6S,8R)...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300997 (6-((6S,8R)-7- (2-fluoro-2- methylpropyl)- 8-methyl...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300999 (6-((6S,8R)-7- (2- fluoropropyl)- 8-methyl- 6,7,8,9...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300963 (2-fluoro-N-(1-(3-fluoropropyl)azetidin-3-yl)-6-((6...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300959 (6-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8,9-...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300999 (6-((6S,8R)-7- (2- fluoropropyl)- 8-methyl- 6,7,8,9...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300964 (5-fluoro-N-(1-(3-fluoropropyl)azetidin-3-yl)-6-((6...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300924 (6-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-methy...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300952 (5-fluoro-6-((6S,8R)-7-((1-fluorocyclopropyl)methyl...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300980 (6-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300965 (2,2-Difluoro-3-((6S,8R)-6-(3-fluoro-5-((1-(3-fluor...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300996 (2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(6- fluoro-5-...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM301001 (1-(3- fluoropropyl)- N-(4-((6S,8R)- 7-(2- fluoropr...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300992 (2,2-difluoro-3- ((6S,8R)-6-(5- ((1-(3- fluoropropy...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM436275 (2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(5- ((1-(3- f...) | PDB GoogleScholar | UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300989 (5-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- ...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300950 (2,2-difluoro-3-((6S,8R)-6-(5-((1-(3-fluoropropyl)a...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300993 (2,2-difluoro-3- ((6S,8R)-6-(3- fluoro-5-((1- (3- f...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Estrogen receptor(ER) (aa 307-554) (Homo sapiens (Human)) | BDBM300921 (6-((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-8-meth...) | PDB GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca AB US Patent | Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay... | US Patent US10590130 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
