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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230876 (US10045974, 12 | US10603310, Compound 12 | US93467...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230869 (US10045974, 13 | US10603310, Compound 13 | US93467...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM228168 ((S)-N-(3-(6-amino-2-(difluoromethyl)-3,3-difluoro-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230871 (US10045974, 7 | US10603310, Compound 7 | US9346797...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM228170 ((S)-N-(3-(6-amino-2-(difluoromethyl)-3,3-difluoro-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230867 (US10045974, 14 | US10603310, Compound 14 | US93467...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230869 (US10045974, 13 | US10603310, Compound 13 | US93467...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230874 (US10045974, 10 | US10603310, Compound 10 | US93467...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230865 (US10045974, 1 | US10603310, Compound 1 | US9346797...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230867 (US10045974, 14 | US10603310, Compound 14 | US93467...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230870 (US10045974, 6 | US10603310, Compound 6 | US9346797...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230868 (US10045974, 4 | US10603310, Compound 4 | US9346797...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230866 (US10045974, 2 | US10603310, Compound 2 | US9346797...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-secretase (BACE) (Homo sapiens (Human)) | BDBM230872 (US10045974, 8 | US10603310, Compound 8 | US9346797...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S US Patent | Assay Description The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr... | US Patent US10603310 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
