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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM436056 (4-[7-({7-[2-Methoxy-4-trifluoromethylphenyl]-6-met...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM436067 (4-[7-({8-[2-Methoxy-4-(trifluoromethyl)phenyl]quin...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377011 (3-Methoxy-4-(2-{[4-(piperidin-4-yl)-2,3-dihydro-1-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377016 (N-[7-(2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimi...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM376996 (7-(2-Methylphenyl)-N-[4-(piperidin-4-yl)-2,3-dihyd...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377014 (4-[7-({8-[2-Methoxy-4-trifluoromethylphenyl]quinaz...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377013 (8-(4-Methylsulfonyl-2-methoxyphenyl)-N-[2-methyl-4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377005 (8-(4-Fluoro-2-methoxyphenyl)-N-[4-(piperidin-4-yl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM436049 (N-(2-(2-((2-Methoxy-4-(piperidin-4-yl)phenyl)amino...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM376994 (N-[2-Methoxy-4-(piperidin-4-yl)phenyl]-7-(2-methox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM376999 (7-[2-Methoxy-4-trifluoromethylphenyl]-6-methyl-N-[...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM376997 (7-(2-Ethoxyphenyl)-6-methyl-N-[4-(piperidin-4-yl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377018 (N-[2,2-dimethyl-4-(piperidin-4-yl)-2,3-dihydro-1-b...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.9 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377015 (7-{[8-(4-Fluoro-2-methoxyphenyl)quinazolin-2-yl]am...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377002 (8-(2-Methoxyphenyl)-N-[4-(piperidin-4-yl)-2,3-dihy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377000 (N-[2-methoxy-4-(piperidin-4-yl)phenyl]-8-(2-methox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.8 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM436065 (8-(5-Fluoro-2-methoxyphenyl)-N-[4-(piperidin-4-yl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377012 (8-(4-Methylsulfonyl-2-methoxyphenyl)-N-[4-(piperid...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377008 (8-[2-Methoxy-4-(trifluoromethyl)phenyl])-N-[4-(pip...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM436050 (7-(2,3-Dihydro-1-benzofuran-7-yl)-N-(2-methoxy-4-(...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377004 (8-(2-Methoxyphenyl)-N-[3-(piperidin-4-yl)-1-isopro...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM436052 (7-(2-Methylphenyl)-N-[4-(piperidin-4-yl)-2-isoprop...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 27.7 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377006 (8-(4-Fluoro-2-methoxyphenyl)-N-[3-(piperidin-4-yl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377001 (6-Fluoro-8-(2-methoxyphenyl)-N-[4-(piperidin-4-yl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377010 (8-{2-Methoxy-4-[(morpholin-4-yl)carbonyl]phenyl}-N...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM377003 (N-[2,2-Dimethyl-4-(piperidin-4-yl)-2,3-dihydro-1-b...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. US Patent | Assay Description Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel... | US Patent US10611770 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
