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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439528 (US10633379, Example 64) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439590 (US10633379, Example 121) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439589 (US10633379, Example 120) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439575 (US10633379, Example 107) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439516 (US10633379, Example 52) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM220447 (US10633379, Compound X | US9296741, 36) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid PDB UniChem | US Patent | 0.952 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439513 (US10633379, Example 49) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439592 (US10633379, Example 123) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439548 (US10633379, Example 83) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439553 (US10633379, Example 88) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439531 (US10633379, Example 67) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439546 (US10633379, Example 81) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439461 (US10633379, Example 3 | US10633379, Example 68) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439577 (US10633379, Example 109) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439572 (US10633379, Example 104) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439536 (US10633379, Example 72) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439598 (US10633379, Example 128) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439583 (US10633379, Example 114) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439514 (US10633379, Example 50) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439529 (US10633379, Example 65) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439490 (US10633379, Example 29) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439584 (US10633379, Example 115) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439530 (US10633379, Example 66) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439497 (US10633379, Example 35 | US10633379, Example 82) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | PDB UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439580 (4-[4′,4′-difluoro-4-(2-hydroxypropan-2...) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439497 (US10633379, Example 35 | US10633379, Example 82) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | PDB UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439551 (US10633379, Example 86) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439582 (N-ethyl-4-[4-(2-hydroxypropan-2-yl)-4′-methy...) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439586 (US10633379, Example 117) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439482 (US10633379, Example 21) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439538 (US10633379, Example 73) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439527 (US10633379, Example 63) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439487 (US10633379, Example 26) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439463 (US10633379, Example 5) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439576 (US10633379, Example 108) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439556 (US10633379, Example 91) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439593 (US10633379, Example 124) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439554 (US10633379, Example 89) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439485 (US10633379, Example 24) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439566 (US10633379, Example 99) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439488 (US10633379, Example 27) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439550 (US10633379, Example 85) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439470 (US10633379, Example 12) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439549 (US10633379, Example 84) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439491 (US10633379, Example 30) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439472 (US10633379, Example 13) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439555 (US10633379, Example 90) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439591 (US10633379, Example 122) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human)) | BDBM439579 (N-ethyl-4-[4-(2-hydroxypropan-2-yl)-4′-(trif...) | PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar | UniChem | US Patent | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (BRD4)(aa 57-168) (Homo sapiens (Human)) | BDBM220447 (US10633379, Compound X | US9296741, 36) | PDB GoogleScholar | PC cid PC sid PDB UniChem | US Patent | 2.09 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo... | US Patent US10633379 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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