BindingDB logo
myBDB logout

Patent code US10640498

Compile Data Set for Download or QSAR
Found 69 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441759
PNG
((R)-3-(5-(3-Chlorophenyl)-2,3-dihydro-1H-pyrrolo[2...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)N1CCc2cc(cnc12)-c1cccc(Cl)c1
Show InChI InChI=1S/C19H16ClFN4O/c20-16-3-1-2-13(9-16)15-8-14-4-6-25(17(14)23-10-15)18(26)19(21)5-7-24(11-19)12-22/h1-3,8-10H,4-7,11H2/t19-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441743
PNG
(3-Fluoro-3-(5-(2-fluoro-5- methylphenyl)indoline-1...)
Show SMILES Cc1ccc(F)c(c1)-c1ccc2N(CCc2c1)C(=O)C1(F)CCN(C1)C#N
Show InChI InChI=1S/C21H19F2N3O/c1-14-2-4-18(22)17(10-14)15-3-5-19-16(11-15)6-8-26(19)20(27)21(23)7-9-25(12-21)13-24/h2-5,10-11H,6-9,12H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441755
PNG
(Trans-3-methyl-4-(5-phenyl-2,3-dihydro-1H-pyrrolo[...)
Show SMILES C[C@H]1CN(C[C@@H]1C(=O)N1CCc2cc(cnc12)-c1ccccc1)C#N
Show InChI InChI=1S/C20H20N4O/c1-14-11-23(13-21)12-18(14)20(25)24-8-7-16-9-17(10-22-19(16)24)15-5-3-2-4-6-15/h2-6,9-10,14,18H,7-8,11-12H2,1H3/t14-,18-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441713
PNG
(US10640498, Example 10)
Show SMILES O=C([C@H]1CCN(C1)C#N)N1CCc2c1cccc2-c1ccccc1
Show InChI InChI=1S/C20H19N3O/c21-14-22-11-9-16(13-22)20(24)23-12-10-18-17(7-4-8-19(18)23)15-5-2-1-3-6-15/h1-8,16H,9-13H2/t16-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441715
PNG
((S)-3-(5-(3-Chlorophenyl)indoline-1-carbonyl)pyrro...)
Show SMILES Clc1cccc(c1)-c1ccc2N(CCc2c1)C(=O)[C@H]1CCN(C1)C#N
Show InChI InChI=1S/C20H18ClN3O/c21-18-3-1-2-14(11-18)15-4-5-19-16(10-15)7-9-24(19)20(25)17-6-8-23(12-17)13-22/h1-5,10-11,17H,6-9,12H2/t17-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441706
PNG
(US10640498, Example 3)
Show SMILES CN(C(=O)[C@H]1CCN(C1)C#N)c1ncc(s1)-c1ccccc1
Show InChI InChI=1S/C16H16N4OS/c1-19(15(21)13-7-8-20(10-13)11-17)16-18-9-14(22-16)12-5-3-2-4-6-12/h2-6,9,13H,7-8,10H2,1H3/t13-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441711
PNG
(1-Cyano-3-fluoro-N-methyl-N-(5-phenylthiazol-2-yl)...)
Show SMILES CN(C(=O)C1(F)CCN(C1)C#N)c1ncc(s1)-c1ccccc1
Show InChI InChI=1S/C16H15FN4OS/c1-20(14(22)16(17)7-8-21(10-16)11-18)15-19-9-13(23-15)12-5-3-2-4-6-12/h2-6,9H,7-8,10H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441725
PNG
(3-Fluoro-3-(5-phenyl-2,3-dihydro-1H-pyrrolo[2,3-b]...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(cnc12)-c1ccccc1
Show InChI InChI=1S/C19H17FN4O/c20-19(7-9-23(12-19)13-21)18(25)24-8-6-15-10-16(11-22-17(15)24)14-4-2-1-3-5-14/h1-5,10-11H,6-9,12H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441728
PNG
((R)-3-(6-Phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazin...)
Show SMILES O=C([C@@H]1CCN(C1)C#N)N1CCOc2ccc(cc12)-c1ccccc1
Show InChI InChI=1S/C20H19N3O2/c21-14-22-9-8-17(13-22)20(24)23-10-11-25-19-7-6-16(12-18(19)23)15-4-2-1-3-5-15/h1-7,12,17H,8-11,13H2/t17-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441736
PNG
(1-Cyano-3-fluoro-N-methyl-N-(5-phenylisoxazol-3-yl...)
Show SMILES CN(C(=O)C1(F)CCN(C1)C(=O)OC(C)(C)C)c1cc(on1)-c1ccccc1
Show InChI InChI=1S/C20H24FN3O4/c1-19(2,3)27-18(26)24-11-10-20(21,13-24)17(25)23(4)16-12-15(28-22-16)14-8-6-5-7-9-14/h5-9,12H,10-11,13H2,1-4H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441737
PNG
((trans)-1-Cyano-4-(hydroxymethyl)-N-methyl-N-(5-ph...)
Show SMILES CCOC(=O)[C@H]1CN(Cc2ccccc2)C[C@@H]1C(=O)Nc1ncc(s1)-c1ccccc1
Show InChI InChI=1S/C24H25N3O3S/c1-2-30-23(29)20-16-27(14-17-9-5-3-6-10-17)15-19(20)22(28)26-24-25-13-21(31-24)18-11-7-4-8-12-18/h3-13,19-20H,2,14-16H2,1H3,(H,25,26,28)/t19-,20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441763
PNG
(US10640498, Example 60)
Show SMILES O=C([C@H]1CCN(C1)C#N)N1CCc2cc(cnc12)-c1cccc2[nH]ncc12
Show InChI InChI=1S/C20H18N6O/c21-12-25-6-4-14(11-25)20(27)26-7-5-13-8-15(9-22-19(13)26)16-2-1-3-18-17(16)10-23-24-18/h1-3,8-10,14H,4-7,11H2,(H,23,24)/t14-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441716
PNG
((trans)-3-(5-(2-Chlorophenyl)indoline-1-carbonyl)-...)
Show SMILES C[C@@H]1CN(C[C@H]1C(=O)N1CCc2cc(ccc12)-c1ccccc1Cl)C#N
Show InChI InChI=1S/C21H20ClN3O/c1-14-11-24(13-23)12-18(14)21(26)25-9-8-16-10-15(6-7-20(16)25)17-4-2-3-5-19(17)22/h2-7,10,14,18H,8-9,11-12H2,1H3/t14-,18-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441717
PNG
(3-Fluoro-3-(5-phenylindoline-1-carbonyl)pyrrolidin...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1ccccc1
Show InChI InChI=1S/C20H18FN3O/c21-20(9-11-23(13-20)14-22)19(25)24-10-8-17-12-16(6-7-18(17)24)15-4-2-1-3-5-15/h1-7,12H,8-11,13H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441719
PNG
(3-Fluoro-3-(6-phenyl-2,3-dihydro-1-H-pyrrolo[2,3-b...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2ccc(nc12)-c1ccccc1
Show InChI InChI=1S/C19H17FN4O/c20-19(9-11-23(12-19)13-21)18(25)24-10-8-15-6-7-16(22-17(15)24)14-4-2-1-3-5-14/h1-7H,8-12H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441726
PNG
((S)-3-(6-Phenyl-1,2,3,4-tetrahydroquinoline-1-carb...)
Show SMILES O=C([C@H]1CCN(C1)C#N)N1CCCc2cc(ccc12)-c1ccccc1
Show InChI InChI=1S/C21H21N3O/c22-15-23-12-10-19(14-23)21(25)24-11-4-7-18-13-17(8-9-20(18)24)16-5-2-1-3-6-16/h1-3,5-6,8-9,13,19H,4,7,10-12,14H2/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441753
PNG
((R)-3-(4-(3-Ethylphenyl)indoline-1-carbonyl)pyrrol...)
Show SMILES CCc1cccc(c1)-c1cccc2N(CCc12)C(=O)[C@@H]1CCN(C1)C#N
Show InChI InChI=1S/C22H23N3O/c1-2-16-5-3-6-17(13-16)19-7-4-8-21-20(19)10-12-25(21)22(26)18-9-11-24(14-18)15-23/h3-8,13,18H,2,9-12,14H2,1H3/t18-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441742
PNG
(3-Fluoro-3-(5-(1-methyl-1H-indazol-5- yl)indoline-...)
Show SMILES Cn1ncc2cc(ccc12)-c1ccc2N(CCc2c1)C(=O)C1(F)CCN(C1)C#N
Show InChI InChI=1S/C22H20FN5O/c1-26-19-4-2-16(11-18(19)12-25-26)15-3-5-20-17(10-15)6-8-28(20)21(29)22(23)7-9-27(13-22)14-24/h2-5,10-12H,6-9,13H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441744
PNG
(3-Fluoro-3-(5-(5-methyl-1H-indazol-4- yl)indoline-...)
Show SMILES Cc1ccc2[nH]ncc2c1-c1ccc2N(CCc2c1)C(=O)C1(F)CCN(C1)C#N
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441750
PNG
(1-Cyano-N-methyl-N-((2-phenylthiazol-4-yl)methyl)p...)
Show SMILES CN(Cc1csc(n1)-c1ccccc1)C(=O)C1CCN(C1)C#N
Show InChI InChI=1S/C17H18N4OS/c1-20(17(22)14-7-8-21(9-14)12-18)10-15-11-23-16(19-15)13-5-3-2-4-6-13/h2-6,11,14H,7-10H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441752
PNG
(7-([1,1′-Biphenyl]-3-yl)-6-oxo-2,7-diazaspir...)
Show SMILES CC(C)(C)OC(=O)N1CCC2(CCN(C2=O)c2cccc(c2)-c2ccccc2)C1
Show InChI InChI=1S/C24H28N2O3/c1-23(2,3)29-22(28)25-14-12-24(17-25)13-15-26(21(24)27)20-11-7-10-19(16-20)18-8-5-4-6-9-18/h4-11,16H,12-15,17H2,1-3H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441758
PNG
((S)-3-(5-(3-Chlorophenyl)-2,3-dihydro-1H-pyrrolo[2...)
Show SMILES F[C@]1(CCN(C1)C#N)C(=O)N1CCc2cc(cnc12)-c1cccc(Cl)c1
Show InChI InChI=1S/C19H16ClFN4O/c20-16-3-1-2-13(9-16)15-8-14-4-6-25(17(14)23-10-15)18(26)19(21)5-7-24(11-19)12-22/h1-3,8-10H,4-7,11H2/t19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441760
PNG
(3-Fluoro-3-(5-(pyridin-3-yl)indoline-1-carbonyl)py...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1cccnc1
Show InChI InChI=1S/C19H17FN4O/c20-19(6-9-23(12-19)13-21)18(25)24-8-5-15-10-14(3-4-17(15)24)16-2-1-7-22-11-16/h1-4,7,10-11H,5-6,8-9,12H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441768
PNG
(3-(5-(1-(3-Chlorobenzyl)-1H-pyrazol-5-yl)indoline-...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1ccnn1Cc1cccc(Cl)c1
Show InChI InChI=1S/C24H21ClFN5O/c25-20-3-1-2-17(12-20)14-31-22(6-9-28-31)18-4-5-21-19(13-18)7-10-30(21)23(32)24(26)8-11-29(15-24)16-27/h1-6,9,12-13H,7-8,10-11,14-15H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441769
PNG
(3-(5-(1-(4-Chlorobenzyl)-1H-pyrazol-5-yl)indoline-...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1ccnn1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C24H21ClFN5O/c25-20-4-1-17(2-5-20)14-31-22(7-10-28-31)18-3-6-21-19(13-18)8-11-30(21)23(32)24(26)9-12-29(15-24)16-27/h1-7,10,13H,8-9,11-12,14-15H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441721
PNG
((S)-3-(5-Phenylindoline-1-carbonyl)pyrrolidine-1-c...)
Show SMILES O=C([C@H]1CCN(C1)C#N)N1CCc2cc(ccc12)-c1ccccc1
Show InChI InChI=1S/C20H19N3O/c21-14-22-10-8-18(13-22)20(24)23-11-9-17-12-16(6-7-19(17)23)15-4-2-1-3-5-15/h1-7,12,18H,8-11,13H2/t18-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441722
PNG
(US10640498, Example 19)
Show SMILES C[C@@H]1CN(C[C@H]1C(=O)N1CCc2cc(ccc12)-c1ccccc1)C#N
Show InChI InChI=1S/C21H21N3O/c1-15-12-23(14-22)13-19(15)21(25)24-10-9-18-11-17(7-8-20(18)24)16-5-3-2-4-6-16/h2-8,11,15,19H,9-10,12-13H2,1H3/t15-,19-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441727
PNG
((R)-3-(7-Phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazin...)
Show SMILES CC(C)(C)OC(=O)N1CC[C@H](C1)C(=O)N1CCOc2cc(ccc12)-c1ccccc1
Show InChI InChI=1S/C24H28N2O4/c1-24(2,3)30-23(28)25-12-11-19(16-25)22(27)26-13-14-29-21-15-18(9-10-20(21)26)17-7-5-4-6-8-17/h4-10,15,19H,11-14,16H2,1-3H3/t19-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441712
PNG
(N-(Benzo[d]thiazol-2-yl)-1-cyano-3-fluoro-N-methyl...)
Show SMILES CN(C(=O)C1(F)CCN(C1)C#N)c1nc2ccccc2s1
Show InChI InChI=1S/C14H13FN4OS/c1-18(12(20)14(15)6-7-19(8-14)9-16)13-17-10-4-2-3-5-11(10)21-13/h2-5H,6-8H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441718
PNG
(3-Fluoro-3-(6-phenylindoline-1-carbonyl)pyrrolidin...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2ccc(cc12)-c1ccccc1
Show InChI InChI=1S/C20H18FN3O/c21-20(9-11-23(13-20)14-22)19(25)24-10-8-16-6-7-17(12-18(16)24)15-4-2-1-3-5-15/h1-7,12H,8-11,13H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441739
PNG
(3-Fluoro-3-(5-(1-methyl-1H-pyrazol-5- yl)indoline-...)
Show SMILES Cn1nccc1-c1ccc2N(CCc2c1)C(=O)C1(F)CCN(C1)C#N
Show InChI InChI=1S/C18H18FN5O/c1-22-15(4-7-21-22)13-2-3-16-14(10-13)5-8-24(16)17(25)18(19)6-9-23(11-18)12-20/h2-4,7,10H,5-6,8-9,11H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441745
PNG
(N-(3-(1-(1-Cyano-3-fluoropyrrolidine- 3-carbonyl)i...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1cccc(NS(=O)(=O)C2CC2)c1
Show InChI InChI=1S/C23H23FN4O3S/c24-23(9-11-27(14-23)15-25)22(29)28-10-8-18-12-17(4-7-21(18)28)16-2-1-3-19(13-16)26-32(30,31)20-5-6-20/h1-4,7,12-13,20,26H,5-6,8-11,14H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441756
PNG
((S)-3-Fluoro-3-(5-phenylindoline-1-carbonyl)pyrrol...)
Show SMILES F[C@]1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1ccccc1
Show InChI InChI=1S/C20H18FN3O/c21-20(9-11-23(13-20)14-22)19(25)24-10-8-17-12-16(6-7-18(17)24)15-4-2-1-3-5-15/h1-7,12H,8-11,13H2/t20-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441757
PNG
((R)-3-Fluoro-3-(5-phenylindoline-1-carbonyl)pyrrol...)
Show SMILES F[C@@]1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1ccccc1
Show InChI InChI=1S/C20H18FN3O/c21-20(9-11-23(13-20)14-22)19(25)24-10-8-17-12-16(6-7-18(17)24)15-4-2-1-3-5-15/h1-7,12H,8-11,13H2/t20-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441771
PNG
((R)-1-(1-Cyanopyrrolidine-3-carbonyl)-4-(3-ethylph...)
Show SMILES CCc1cccc(c1)-c1cc(cc2N(CCc12)C(=O)[C@@H]1CCN(C1)C(=O)OC(C)(C)C)C(=O)NC
Show InChI InChI=1S/C28H35N3O4/c1-6-18-8-7-9-19(14-18)23-15-21(25(32)29-5)16-24-22(23)11-13-31(24)26(33)20-10-12-30(17-20)27(34)35-28(2,3)4/h7-9,14-16,20H,6,10-13,17H2,1-5H3,(H,29,32)/t20-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441746
PNG
(3-Fluoro-3-(5-(6-methoxypyridin-3- yl)indoline-1-c...)
Show SMILES COc1ccc(cn1)-c1ccc2N(CCc2c1)C(=O)C1(F)CCN(C1)C#N
Show InChI InChI=1S/C20H19FN4O2/c1-27-18-5-3-16(11-23-18)14-2-4-17-15(10-14)6-8-25(17)19(26)20(21)7-9-24(12-20)13-22/h2-5,10-11H,6-9,12H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441730
PNG
((S)-3-(4-Phenyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyrid...)
Show SMILES O=C([C@H]1CCN(C1)C#N)N1CCc2c1nccc2-c1ccccc1
Show InChI InChI=1S/C19H18N4O/c20-13-22-10-7-15(12-22)19(24)23-11-8-17-16(6-9-21-18(17)23)14-4-2-1-3-5-14/h1-6,9,15H,7-8,10-12H2/t15-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441723
PNG
(US10640498, Example 20)
Show SMILES C[C@H]1CN(C[C@@H]1C(=O)N1CCc2cc(ccc12)-c1ccccc1)C#N
Show InChI InChI=1S/C21H21N3O/c1-15-12-23(14-22)13-19(15)21(25)24-10-9-18-11-17(7-8-20(18)24)16-5-3-2-4-6-16/h2-8,11,15,19H,9-10,12-13H2,1H3/t15-,19-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441732
PNG
((S)-1-(1-Cyanopyrrolidine-3-carbonyl)-5-(1-methyl-...)
Show SMILES Cn1cc(cn1)-c1cc2CCN(C(=O)[C@H]3CCN(C3)C#N)c2cc1C#N
Show InChI InChI=1S/C19H18N6O/c1-23-10-16(9-22-23)17-6-13-3-5-25(18(13)7-15(17)8-20)19(26)14-2-4-24(11-14)12-21/h6-7,9-10,14H,2-5,11H2,1H3/t14-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441764
PNG
((R)-3-(5-(1H-Indazol-4-yl)-2,3-dihydro-1H-pyrrolo[...)
Show SMILES O=C([C@@H]1CCN(C1)C#N)N1CCc2cc(cnc12)-c1cccc2[nH]ncc12
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441765
PNG
(3-Fluoro-3-(5-(1-(pyridin-2-ylmethyl)-1H-pyrazol-5...)
Show SMILES CC(C)(C)OC(=O)N1CCC(F)(C1)C(=O)N1CCc2cc(ccc12)-c1ccnn1Cc1ccccn1
Show InChI InChI=1S/C27H30FN5O3/c1-26(2,3)36-25(35)31-15-11-27(28,18-31)24(34)32-14-10-20-16-19(7-8-22(20)32)23-9-13-30-33(23)17-21-6-4-5-12-29-21/h4-9,12-13,16H,10-11,14-15,17-18H2,1-3H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441767
PNG
(3-(5-(1-(2-Chlorobenzyl)-1H-pyrazol-5-yl)indoline-...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1ccnn1Cc1ccccc1Cl
Show InChI InChI=1S/C24H21ClFN5O/c25-20-4-2-1-3-19(20)14-31-22(7-10-28-31)17-5-6-21-18(13-17)8-11-30(21)23(32)24(26)9-12-29(15-24)16-27/h1-7,10,13H,8-9,11-12,14-15H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441731
PNG
((S)-3-(4-(3-Chlorophenyl)-2,3-dihydro-1H-pyrrolo[2...)
Show SMILES Clc1cccc(c1)-c1ccnc2N(CCc12)C(=O)[C@H]1CCN(C1)C#N
Show InChI InChI=1S/C19H17ClN4O/c20-15-3-1-2-13(10-15)16-4-7-22-18-17(16)6-9-24(18)19(25)14-5-8-23(11-14)12-21/h1-4,7,10,14H,5-6,8-9,11H2/t14-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441734
PNG
((S)-1-Cyano-N-methyl-N-(5-phenylpyridin-2-yl)pyrro...)
Show SMILES CN(C(=O)[C@@H]1CCN(C1)C#N)c1ccc(cn1)-c1ccccc1
Show InChI InChI=1S/C18H18N4O/c1-21(18(23)16-9-10-22(12-16)13-19)17-8-7-15(11-20-17)14-5-3-2-4-6-14/h2-8,11,16H,9-10,12H2,1H3/t16-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441741
PNG
(3-Fluoro-3-(5-(4-(4-methylpiperazin-1- yl)phenyl)i...)
Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1ccc2N(CCc2c1)C(=O)C1(F)CCN(C1)C#N
Show InChI InChI=1S/C25H28FN5O/c1-28-12-14-30(15-13-28)22-5-2-19(3-6-22)20-4-7-23-21(16-20)8-10-31(23)24(32)25(26)9-11-29(17-25)18-27/h2-7,16H,8-15,17H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441704
PNG
(US10640498, Example 1)
Show SMILES CCN(C(=O)C1CCN(C1)C#N)c1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C17H18N4OS/c1-2-21(16(22)14-8-9-20(10-14)12-18)17-19-15(11-23-17)13-6-4-3-5-7-13/h3-7,11,14H,2,8-10H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441707
PNG
((S)-1-Cyano-N-methyl-N-(4-phenylpyridin-2-yl)pyrro...)
Show SMILES CN(C(=O)[C@H]1CCN(C1)C(=O)OC(C)(C)C)c1cc(ccn1)-c1ccccc1
Show InChI InChI=1S/C22H27N3O3/c1-22(2,3)28-21(27)25-13-11-18(15-25)20(26)24(4)19-14-17(10-12-23-19)16-8-6-5-7-9-16/h5-10,12,14,18H,11,13,15H2,1-4H3/t18-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441733
PNG
((R)-3-(7-(1H-Pyrazol-1-yl)-3,4-dihydro-2H-benzo[b]...)
Show SMILES O=C([C@@H]1CCN(C1)C#N)N1CCOc2cc(ccc12)-n1cccn1
Show InChI InChI=1S/C17H17N5O2/c18-12-20-7-4-13(11-20)17(23)21-8-9-24-16-10-14(2-3-15(16)21)22-6-1-5-19-22/h1-3,5-6,10,13H,4,7-9,11H2/t13-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441735
PNG
((R)-1-Cyano-N-methyl-N-(5-phenylpyridazin-3-yl)pyr...)
Show SMILES CN(C(=O)[C@@H]1CCN(C1)C(=O)OC(C)(C)C)c1cc(cnn1)-c1ccccc1
Show InChI InChI=1S/C21H26N4O3/c1-21(2,3)28-20(27)25-11-10-16(14-25)19(26)24(4)18-12-17(13-22-23-18)15-8-6-5-7-9-15/h5-9,12-13,16H,10-11,14H2,1-4H3/t16-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441738
PNG
(US10640498, Example 35)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1ccnn1Cc1ccccc1
Show InChI InChI=1S/C24H22FN5O/c25-24(10-13-28(16-24)17-26)23(31)29-12-9-20-14-19(6-7-21(20)29)22-8-11-27-30(22)15-18-4-2-1-3-5-18/h1-8,11,14H,9-10,12-13,15-16H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441749
PNG
(1-Cyano-N-methyl-N-((3-phenylisoxazol-5-yl)methyl)...)
Show SMILES CN(Cc1cc(no1)-c1ccccc1)C(=O)C1CCN(C1)C#N
Show InChI InChI=1S/C17H18N4O2/c1-20(17(22)14-7-8-21(10-14)12-18)11-15-9-16(19-23-15)13-5-3-2-4-6-13/h2-6,9,14H,7-8,10-11H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441762
PNG
(3-(5-(1-Benzyl-1H-pyrazol-4-yl)indoline-1-carbonyl...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1cnn(Cc2ccccc2)c1
Show InChI InChI=1S/C24H22FN5O/c25-24(9-11-28(16-24)17-26)23(31)30-10-8-20-12-19(6-7-22(20)30)21-13-27-29(15-21)14-18-4-2-1-3-5-18/h1-7,12-13,15H,8-11,14,16H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441766
PNG
(3-Fluoro-3-(5-(1-(pyridin-3-ylmethyl)-H-pyrazol-5-...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)-c1ccnn1Cc1cccnc1
Show InChI InChI=1S/C23H21FN6O/c24-23(7-11-28(15-23)16-25)22(31)29-10-6-19-12-18(3-4-20(19)29)21-5-9-27-30(21)14-17-2-1-8-26-13-17/h1-5,8-9,12-13H,6-7,10-11,14-15H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441710
PNG
(1-Cyano-N-isopropyl-N-(4-phenylthiazol-2-yl)pyrrol...)
Show SMILES CC(C)N(C(=O)C1CCN(C1)C(=O)OC(C)(C)C)c1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C22H29N3O3S/c1-15(2)25(20-23-18(14-29-20)16-9-7-6-8-10-16)19(26)17-11-12-24(13-17)21(27)28-22(3,4)5/h6-10,14-15,17H,11-13H2,1-5H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441739
PNG
(3-Fluoro-3-(5-(1-methyl-1H-pyrazol-5- yl)indoline-...)
Show SMILES Cn1nccc1-c1ccc2N(CCc2c1)C(=O)C1(F)CCN(C1)C#N
Show InChI InChI=1S/C18H18FN5O/c1-22-15(4-7-21-22)13-2-3-16-14(10-13)5-8-24(16)17(25)18(19)6-9-23(11-18)12-20/h2-4,7,10H,5-6,8-9,11H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441761
PNG
(3-Fluoro-3-(5-(1-isobutyl-1H-pyrazol-5-yl)indoline...)
Show SMILES CC(C)Cn1nccc1-c1ccc2N(CCc2c1)C(=O)C1(F)CCN(C1)C#N
Show InChI InChI=1S/C21H24FN5O/c1-15(2)12-27-19(5-8-24-27)16-3-4-18-17(11-16)6-9-26(18)20(28)21(22)7-10-25(13-21)14-23/h3-5,8,11,15H,6-7,9-10,12-13H2,1-2H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441770
PNG
( N-Benzyl-1-(1-cyano-3-fluoropyrrolidine-3-carbony...)
Show SMILES FC1(CCN(C1)C#N)C(=O)N1CCc2cc(ccc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C22H21FN4O2/c23-22(9-11-26(14-22)15-24)21(29)27-10-8-17-12-18(6-7-19(17)27)20(28)25-13-16-4-2-1-3-5-16/h1-7,12H,8-11,13-14H2,(H,25,28)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441708
PNG
((S)-1-Cyano-N-methyl-N-(6-phenylpyridin-2-yl)pyrro...)
Show SMILES CN(C(=O)[C@H]1CCN(C1)C#N)c1cccc(n1)-c1ccccc1
Show InChI InChI=1S/C18H18N4O/c1-21(18(23)15-10-11-22(12-15)13-19)17-9-5-8-16(20-17)14-6-3-2-4-7-14/h2-9,15H,10-12H2,1H3/t15-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441724
PNG
((S)-3-(5-Phenyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyrid...)
Show SMILES O=C([C@H]1CCN(C1)C#N)N1CCc2cc(cnc12)-c1ccccc1
Show InChI InChI=1S/C19H18N4O/c20-13-22-8-6-16(12-22)19(24)23-9-7-15-10-17(11-21-18(15)23)14-4-2-1-3-5-14/h1-5,10-11,16H,6-9,12H2/t16-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441751
PNG
((cis)-4-Oxo-5-(5-phenylthiazol-2-yl)hexahydropyrro...)
Show SMILES CC(C)(C)OC(=O)N1C[C@H]2CN(C(=O)[C@H]2C1)c1ncc(s1)-c1ccccc1
Show InChI InChI=1S/C20H23N3O3S/c1-20(2,3)26-19(25)22-10-14-11-23(17(24)15(14)12-22)18-21-9-16(27-18)13-7-5-4-6-8-13/h4-9,14-15H,10-12H2,1-3H3/t14-,15-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441705
PNG
(1-Cyano-N-ethyl-N-(5-phenylthiazol-2-yl)pyrrolidin...)
Show SMILES CCN(C(=O)C1CCN(C1)C#N)c1ncc(s1)-c1ccccc1
Show InChI InChI=1S/C17H18N4OS/c1-2-21(16(22)14-8-9-20(11-14)12-18)17-19-10-15(23-17)13-6-4-3-5-7-13/h3-7,10,14H,2,8-9,11H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441729
PNG
((R)-3-(8-Phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazin...)
Show SMILES O=C([C@@H]1CCN(C1)C#N)N1CCOc2c1cccc2-c1ccccc1
Show InChI InChI=1S/C20H19N3O2/c21-14-22-10-9-16(13-22)20(24)23-11-12-25-19-17(7-4-8-18(19)23)15-5-2-1-3-6-15/h1-8,16H,9-13H2/t16-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441748
PNG
(US10640498, Example 45)
Show SMILES CN(Cc1nc2ccccc2s1)C(=O)C1CCN(C1)C#N
Show InChI InChI=1S/C15H16N4OS/c1-18(15(20)11-6-7-19(8-11)10-16)9-14-17-12-4-2-3-5-13(12)21-14/h2-5,11H,6-9H2,1H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441754
PNG
(3-(5-Phenyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-...)
Show SMILES O=C(C1CCN(C1)C#N)N1CCc2nc(ccc12)-c1ccccc1
Show InChI InChI=1S/C19H18N4O/c20-13-22-10-8-15(12-22)19(24)23-11-9-17-18(23)7-6-16(21-17)14-4-2-1-3-5-14/h1-7,15H,8-12H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441714
PNG
((R)-3-(6-Phenylindoline-1-carbonyl)pyrrolidine-1-c...)
Show SMILES O=C([C@@H]1CCN(C1)C#N)N1CCc2ccc(cc12)-c1ccccc1
Show InChI InChI=1S/C20H19N3O/c21-14-22-10-8-18(13-22)20(24)23-11-9-16-6-7-17(12-19(16)23)15-4-2-1-3-5-15/h1-7,12,18H,8-11,13H2/t18-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441720
PNG
(US10640498, Example 17)
Show SMILES O=C([C@@H]1CCN(C1)C#N)N1CCc2cc(ccc12)-c1ccccc1
Show InChI InChI=1S/C20H19N3O/c21-14-22-10-8-18(13-22)20(24)23-11-9-17-12-16(6-7-19(17)23)15-4-2-1-3-5-15/h1-7,12,18H,8-11,13H2/t18-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441747
PNG
((R)-1-Cyano-N-(5-(4-cyanophenyl)pyridin-2-yl)-N-et...)
Show SMILES CCN(C(=O)[C@@H]1CCN(C1)C#N)c1ccc(cn1)-c1ccc(cc1)C#N
Show InChI InChI=1S/C20H19N5O/c1-2-25(20(26)18-9-10-24(13-18)14-22)19-8-7-17(12-23-19)16-5-3-15(11-21)4-6-16/h3-8,12,18H,2,9-10,13H2,1H3/t18-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441772
PNG
((R)-1-(1-Cyanopyrrolidine-3-carbonyl)-N-methyl-4-p...)
Show SMILES CNC(=O)c1cc2N(CCc2c(c1)-c1ccccc1)C(=O)[C@@H]1CCN(C1)C#N
Show InChI InChI=1S/C22H22N4O2/c1-24-21(27)17-11-19(15-5-3-2-4-6-15)18-8-10-26(20(18)12-17)22(28)16-7-9-25(13-16)14-23/h2-6,11-12,16H,7-10,13H2,1H3,(H,24,27)/t16-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM441709
PNG
(1-Cyano-N-isopropyl-N-(5-(pyridin-4-yl)thiazol-2-y...)
Show SMILES CC(C)N(C(=O)OC(C)(C)C)c1ncc(s1)B1OC(C)(C)C(C)(C)O1
Show InChI InChI=1S/C17H29BN2O4S/c1-11(2)20(14(21)22-15(3,4)5)13-19-10-12(25-13)18-23-16(6,7)17(8,9)24-18/h10-11H,1-9H3
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
n/an/a 6.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 M for a final concentration of 100 μM) in 50% DMSO in a 96-well polyprop...


US Patent US10640498 (2020)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%