BindingDB logo
myBDB logout

Patent code US10654814

Compile Data Set for Download or QSAR

Found 240 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443054
PNG
(2-((3-(benzyloxy)phenyl)amino)-N- hydroxy-1-methyl...)
Show SMILES Cn1c(Nc2cccc(OCc3ccccc3)c2)nc2cc(ccc12)C(=O)NO
Show InChI InChI=1S/C22H20N4O3/c1-26-20-11-10-16(21(27)25-28)12-19(20)24-22(26)23-17-8-5-9-18(13-17)29-14-15-6-3-2-4-7-15/h2-13,28H,14H2,1H3,(H,23,24)(H,25,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443101
PNG
(N-hydroxy-2-[4-(6-methoxypyridin- 3-yl)phenyl]-1,3...)
Show SMILES COc1ccc(cn1)-c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO
Show InChI InChI=1S/C20H15N3O4/c1-26-18-9-7-15(11-21-18)12-2-4-13(5-3-12)20-22-16-10-14(19(24)23-25)6-8-17(16)27-20/h2-11,25H,1H3,(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443012
PNG
(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzot...)
Show SMILES CC(C)c1ccc(cc1)-c1nc2cc(ccc2s1)C(=O)NO
Show InChI InChI=1S/C17H16N2O2S/c1-10(2)11-3-5-12(6-4-11)17-18-14-9-13(16(20)19-21)7-8-15(14)22-17/h3-10,21H,1-2H3,(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443081
PNG
(2-[(biphenyl-4-ylmethyl)amino]-N- hydroxy-1,3-benz...)
Show SMILES ONC(=O)c1ccc2oc(NCc3ccc(cc3)-c3ccccc3)nc2c1
Show InChI InChI=1S/C21H17N3O3/c25-20(24-26)17-10-11-19-18(12-17)23-21(27-19)22-13-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-12,26H,13H2,(H,22,23)(H,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443087
PNG
(2-[(benzyloxy)methyl]-N-hydroxy- 1,3-benzothiazole...)
Show SMILES ONC(=O)c1ccc2sc(COCc3ccccc3)nc2c1
Show InChI InChI=1S/C16H14N2O3S/c19-16(18-20)12-6-7-14-13(8-12)17-15(22-14)10-21-9-11-4-2-1-3-5-11/h1-8,20H,9-10H2,(H,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443097
PNG
(N-hydroxy-2-(3-hydroxypheny)-1- benzofuran-6-carbo...)
Show SMILES ONC(=O)c1ccc2cc(oc2c1)-c1cccc(O)c1
Show InChI InChI=1S/C15H11NO4/c17-12-3-1-2-9(6-12)13-7-10-4-5-11(15(18)16-19)8-14(10)20-13/h1-8,17,19H,(H,16,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443098
PNG
(N-hydroxy-2-(3-methoxyphenyl)-1- benzofuran-6-carb...)
Show SMILES COc1cccc(c1)-c1cc2ccc(cc2o1)C(=O)NO
Show InChI InChI=1S/C16H13NO4/c1-20-13-4-2-3-10(7-13)14-8-11-5-6-12(16(18)17-19)9-15(11)21-14/h2-9,19H,1H3,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443098
PNG
(N-hydroxy-2-(3-methoxyphenyl)-1- benzofuran-6-carb...)
Show SMILES COc1cccc(c1)-c1cc2ccc(cc2o1)C(=O)NO
Show InChI InChI=1S/C16H13NO4/c1-20-13-4-2-3-10(7-13)14-8-11-5-6-12(16(18)17-19)9-15(11)21-14/h2-9,19H,1H3,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442978
PNG
(2-(4-bromophenyl)-N-hydroxy-1,3- benzoxazole-5-car...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccc(Br)cc1
Show InChI InChI=1S/C14H9BrN2O3/c15-10-4-1-8(2-5-10)14-16-11-7-9(13(18)17-19)3-6-12(11)20-14/h1-7,19H,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442984
PNG
(2-(2-chlorophenyl)-N-hydroxy-1,3- benzoxazole-5-ca...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccccc1Cl
Show InChI InChI=1S/C14H9ClN2O3/c15-10-4-2-1-3-9(10)14-16-11-7-8(13(18)17-19)5-6-12(11)20-14/h1-7,19H,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442990
PNG
(N-hydroxy-2-[4-(4-methoxypyridin- 3-yl)phenyl]-1,3...)
Show SMILES COc1ccncc1-c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO
Show InChI InChI=1S/C20H15N3O4/c1-26-17-8-9-21-11-15(17)12-2-4-13(5-3-12)20-22-16-10-14(19(24)23-25)6-7-18(16)27-20/h2-11,25H,1H3,(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442979
PNG
(2-(4-tert-butylphenyl)-N-hydroxy- 1,3-benzoxazole-...)
Show SMILES CC(C)(C)c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO
Show InChI InChI=1S/C18H18N2O3/c1-18(2,3)13-7-4-11(5-8-13)17-19-14-10-12(16(21)20-22)6-9-15(14)23-17/h4-10,22H,1-3H3,(H,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442979
PNG
(2-(4-tert-butylphenyl)-N-hydroxy- 1,3-benzoxazole-...)
Show SMILES CC(C)(C)c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO
Show InChI InChI=1S/C18H18N2O3/c1-18(2,3)13-7-4-11(5-8-13)17-19-14-10-12(16(21)20-22)6-9-15(14)23-17/h4-10,22H,1-3H3,(H,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442984
PNG
(2-(2-chlorophenyl)-N-hydroxy-1,3- benzoxazole-5-ca...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccccc1Cl
Show InChI InChI=1S/C14H9ClN2O3/c15-10-4-2-1-3-9(10)14-16-11-7-8(13(18)17-19)5-6-12(11)20-14/h1-7,19H,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443089
PNG
(N-hydroxy-2-(4-pyridin-4- ylbenzyl)-1,3-benzothiaz...)
Show SMILES ONC(=O)c1ccc2sc(Cc3ccc(cc3)-c3ccncc3)nc2c1
Show InChI InChI=1S/C20H15N3O2S/c24-20(23-25)16-5-6-18-17(12-16)22-19(26-18)11-13-1-3-14(4-2-13)15-7-9-21-10-8-15/h1-10,12,25H,11H2,(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443096
PNG
(2-{4- [(dimethylamino)methyl]phenyl}-N- hydroxy-1-...)
Show SMILES CN(C)Cc1ccc(cc1)-c1cc2ccc(cc2o1)C(=O)NO
Show InChI InChI=1S/C18H18N2O3/c1-20(2)11-12-3-5-13(6-4-12)16-9-14-7-8-15(18(21)19-22)10-17(14)23-16/h3-10,22H,11H2,1-2H3,(H,19,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442986
PNG
(2-(3-bromophenyl)-N-hydroxy-1,3- benzoxazole-5-car...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1cccc(Br)c1
Show InChI InChI=1S/C14H9BrN2O3/c15-10-3-1-2-9(6-10)14-16-11-7-8(13(18)17-19)4-5-12(11)20-14/h1-7,19H,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443055
PNG
(2-(4-benzylpiperidin-1-yl)-N- hydroxy-1-methyl-1H-...)
Show SMILES Cn1c(nc2cc(ccc12)C(=O)NO)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H24N4O2/c1-24-19-8-7-17(20(26)23-27)14-18(19)22-21(24)25-11-9-16(10-12-25)13-15-5-3-2-4-6-15/h2-8,14,16,27H,9-13H2,1H3,(H,23,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443039
PNG
(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1-benzofura...)
Show SMILES CC(C)c1ccc(cc1)-c1cc2ccc(cc2o1)C(=O)NO
Show InChI InChI=1S/C18H17NO3/c1-11(2)12-3-5-13(6-4-12)16-9-14-7-8-15(18(20)19-21)10-17(14)22-16/h3-11,21H,1-2H3,(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443064
PNG
(2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...)
Show SMILES ONC(=O)c1ccc2oc(COc3cccc(F)c3)cc2c1
Show InChI InChI=1S/C16H12FNO4/c17-12-2-1-3-13(8-12)21-9-14-7-11-6-10(16(19)18-20)4-5-15(11)22-14/h1-8,20H,9H2,(H,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443079
PNG
(2-(biphenyl-3-ylamino)-N-hydroxy- 1,3-benzoxazole-...)
Show SMILES ONC(=O)c1ccc2oc(Nc3cccc(c3)-c3ccccc3)nc2c1
Show InChI InChI=1S/C20H15N3O3/c24-19(23-25)15-9-10-18-17(12-15)22-20(26-18)21-16-8-4-7-14(11-16)13-5-2-1-3-6-13/h1-12,25H,(H,21,22)(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443016
PNG
(2-(4-fluorobenzyl)-N-hydroxy-1,3- benzothiazole-5-...)
Show SMILES ONC(=O)c1ccc2sc(Cc3ccc(F)cc3)nc2c1
Show InChI InChI=1S/C15H11FN2O2S/c16-11-4-1-9(2-5-11)7-14-17-12-8-10(15(19)18-20)3-6-13(12)21-14/h1-6,8,20H,7H2,(H,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443044
PNG
(2-(([1,1'-biphenyl]-4- ylmethyl)amino)-N-hydroxy-1...)
Show SMILES ONC(=O)c1ccc2nc(NCc3ccc(cc3)-c3ccccc3)[nH]c2c1
Show InChI InChI=1S/C21H18N4O2/c26-20(25-27)17-10-11-18-19(12-17)24-21(23-18)22-13-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-12,27H,13H2,(H,25,26)(H2,22,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443056
PNG
(2-([1,1'-biphenyl]-3-ylamino)-N- hydroxy-1-methyl-...)
Show SMILES Cn1c(Nc2cccc(c2)-c2ccccc2)nc2cc(ccc12)C(=O)NO
Show InChI InChI=1S/C21H18N4O2/c1-25-19-11-10-16(20(26)24-27)13-18(19)23-21(25)22-17-9-5-8-15(12-17)14-6-3-2-4-7-14/h2-13,27H,1H3,(H,22,23)(H,24,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443064
PNG
(2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...)
Show SMILES ONC(=O)c1ccc2oc(COc3cccc(F)c3)cc2c1
Show InChI InChI=1S/C16H12FNO4/c17-12-2-1-3-13(8-12)21-9-14-7-11-6-10(16(19)18-20)4-5-15(11)22-14/h1-8,20H,9H2,(H,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443092
PNG
(N-hydroxy-2-({[4-(1- methylethyl)phenyl]amino}meth...)
Show SMILES CC(C)c1ccc(NCc2nc3cc(ccc3s2)C(=O)NO)cc1
Show InChI InChI=1S/C18H19N3O2S/c1-11(2)12-3-6-14(7-4-12)19-10-17-20-15-9-13(18(22)21-23)5-8-16(15)24-17/h3-9,11,19,23H,10H2,1-2H3,(H,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442983
PNG
(N-hydroxy-2-(4-methoxyphenyl)- 1,3-benzoxazole-5-c...)
Show SMILES COc1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO
Show InChI InChI=1S/C15H12N2O4/c1-20-11-5-2-9(3-6-11)15-16-12-8-10(14(18)17-19)4-7-13(12)21-15/h2-8,19H,1H3,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443068
PNG
(N-hydroxy-2-[4'- (methylsulfonyl)biphenyl-4-yl]-1,...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO
Show InChI InChI=1S/C21H16N2O5S/c1-29(26,27)17-9-6-14(7-10-17)13-2-4-15(5-3-13)21-22-18-12-16(20(24)23-25)8-11-19(18)28-21/h2-12,25H,1H3,(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443086
PNG
(N-hydroxy-2-[(4- methylphenyl)amino]-1,3- benzoxaz...)
Show SMILES Cc1ccc(Nc2nc3cc(ccc3o2)C(=O)NO)cc1
Show InChI InChI=1S/C15H13N3O3/c1-9-2-5-11(6-3-9)16-15-17-12-8-10(14(19)18-20)4-7-13(12)21-15/h2-8,20H,1H3,(H,16,17)(H,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 9n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443095
PNG
(N-hydroxy-2-phenyl-1-benzofuran- 6-carboxamide | U...)
Show SMILES ONC(=O)c1ccc2cc(oc2c1)-c1ccccc1
Show InChI InChI=1S/C15H11NO3/c17-15(16-18)12-7-6-11-8-13(19-14(11)9-12)10-4-2-1-3-5-10/h1-9,18H,(H,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 9n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443085
PNG
(2-{[1-(3- fluorophenyl)cyclohexyl]amino}-N- hydrox...)
Show SMILES ONC(=O)c1ccc2oc(NC3(CCCCC3)c3cccc(F)c3)nc2c1
Show InChI InChI=1S/C20H20FN3O3/c21-15-6-4-5-14(12-15)20(9-2-1-3-10-20)23-19-22-16-11-13(18(25)24-26)7-8-17(16)27-19/h4-8,11-12,26H,1-3,9-10H2,(H,22,23)(H,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 9n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443004
PNG
(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzox...)
Show SMILES CC(C)c1ccc(cc1)-c1nc2ccc(cc2o1)C(=O)NO
Show InChI InChI=1S/C17H16N2O3/c1-10(2)11-3-5-12(6-4-11)17-18-14-8-7-13(16(20)19-21)9-15(14)22-17/h3-10,21H,1-2H3,(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 9n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443026
PNG
(N-hydroxy-2-(4-methoxyphenyl)-1- benzothiophene-5-...)
Show SMILES COc1ccc(cc1)-c1cc2cc(ccc2s1)C(=O)NO
Show InChI InChI=1S/C16H13NO3S/c1-20-13-5-2-10(3-6-13)15-9-12-8-11(16(18)17-19)4-7-14(12)21-15/h2-9,19H,1H3,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 9n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443052
PNG
(N-hydroxy-1-methyl-2- (phenethylamino)-1H- benzo[d...)
Show SMILES Cn1c(NCCc2ccccc2)nc2cc(ccc12)C(=O)NO
Show InChI InChI=1S/C17H18N4O2/c1-21-15-8-7-13(16(22)20-23)11-14(15)19-17(21)18-10-9-12-5-3-2-4-6-12/h2-8,11,23H,9-10H2,1H3,(H,18,19)(H,20,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442991
PNG
(2-(4-cyclopropylphenyl)-N- hydroxy-1,3-benzoxazole...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccc(cc1)C1CC1
Show InChI InChI=1S/C17H14N2O3/c20-16(19-21)13-7-8-15-14(9-13)18-17(22-15)12-5-3-11(4-6-12)10-1-2-10/h3-10,21H,1-2H2,(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442991
PNG
(2-(4-cyclopropylphenyl)-N- hydroxy-1,3-benzoxazole...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccc(cc1)C1CC1
Show InChI InChI=1S/C17H14N2O3/c20-16(19-21)13-7-8-15-14(9-13)18-17(22-15)12-5-3-11(4-6-12)10-1-2-10/h3-10,21H,1-2H2,(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443019
PNG
(2-(4-ethylphenyl)-N-hydroxy-1,3- benzothiazole-5-c...)
Show SMILES CCc1ccc(cc1)-c1nc2cc(ccc2s1)C(=O)NO
Show InChI InChI=1S/C16H14N2O2S/c1-2-10-3-5-11(6-4-10)16-17-13-9-12(15(19)18-20)7-8-14(13)21-16/h3-9,20H,2H2,1H3,(H,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443010
PNG
(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1H- imidazo...)
Show SMILES CC(C)c1ccc(cc1)-c1nc2ncc(cc2[nH]1)C(=O)NO
Show InChI InChI=1S/C16H16N4O2/c1-9(2)10-3-5-11(6-4-10)14-18-13-7-12(16(21)20-22)8-17-15(13)19-14/h3-9,22H,1-2H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442989
PNG
(N-hydroxy-2-(4-pyridin-3- ylphenyl)-1,3-benzoxazol...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccc(cc1)-c1cccnc1
Show InChI InChI=1S/C19H13N3O3/c23-18(22-24)14-7-8-17-16(10-14)21-19(25-17)13-5-3-12(4-6-13)15-2-1-9-20-11-15/h1-11,24H,(H,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443015
PNG
(N-hydroxy-2-(4-methoxyphenyl)- 1,3-benzothiazole-5...)
Show SMILES COc1ccc(cc1)-c1nc2cc(ccc2s1)C(=O)NO
Show InChI InChI=1S/C15H12N2O3S/c1-20-11-5-2-9(3-6-11)15-16-12-8-10(14(18)17-19)4-7-13(12)21-15/h2-8,19H,1H3,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 12n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443012
PNG
(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzot...)
Show SMILES CC(C)c1ccc(cc1)-c1nc2cc(ccc2s1)C(=O)NO
Show InChI InChI=1S/C17H16N2O2S/c1-10(2)11-3-5-12(6-4-11)17-18-14-9-13(16(20)19-21)7-8-15(14)22-17/h3-10,21H,1-2H3,(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442988
PNG
(N-hydroxy-2-(4-pyridin-4- ylphenyl)-1,3-benzoxazol...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccc(cc1)-c1ccncc1
Show InChI InChI=1S/C19H13N3O3/c23-18(22-24)15-5-6-17-16(11-15)21-19(25-17)14-3-1-12(2-4-14)13-7-9-20-10-8-13/h1-11,24H,(H,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442982
PNG
(2-(1,3-benzodioxo1-5-yl)-N- hydroxy-1,3-benzoxazol...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccc2OCOc2c1
Show InChI InChI=1S/C15H10N2O5/c18-14(17-19)8-1-3-11-10(5-8)16-15(22-11)9-2-4-12-13(6-9)21-7-20-12/h1-6,19H,7H2,(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 14n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442992
PNG
(N-hydroxy-2-[4'-(piperidin-1- ylmethyl)biphenyl-4-...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C26H25N3O3/c30-25(28-31)22-12-13-24-23(16-22)27-26(32-24)21-10-8-20(9-11-21)19-6-4-18(5-7-19)17-29-14-2-1-3-15-29/h4-13,16,31H,1-3,14-15,17H2,(H,28,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 14n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442998
PNG
(N-hydroxy-2-(phenylamino)-1,3- benzoxazole-5-carbo...)
Show SMILES ONC(=O)c1ccc2oc(Nc3ccccc3)nc2c1
Show InChI InChI=1S/C14H11N3O3/c18-13(17-19)9-6-7-12-11(8-9)16-14(20-12)15-10-4-2-1-3-5-10/h1-8,19H,(H,15,16)(H,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 14n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443023
PNG
(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1- benzothi...)
Show SMILES CC(C)c1ccc(cc1)-c1cc2ccc(cc2s1)C(=O)NO
Show InChI InChI=1S/C18H17NO2S/c1-11(2)12-3-5-13(6-4-12)16-9-14-7-8-15(18(20)19-21)10-17(14)22-16/h3-11,21H,1-2H3,(H,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 14n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM442981
PNG
(N-hydroxy-2-phenyl-1,3- benzoxazole-5-carboxamide ...)
Show SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccccc1
Show InChI InChI=1S/C14H10N2O3/c17-13(16-18)10-6-7-12-11(8-10)15-14(19-12)9-4-2-1-3-5-9/h1-8,18H,(H,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 15n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443090
PNG
(N-hydroxy-2-(piperidin-1- ylmethyl)-1,3-benzothiaz...)
Show SMILES ONC(=O)c1ccc2sc(CN3CCCCC3)nc2c1
Show InChI InChI=1S/C14H17N3O2S/c18-14(16-19)10-4-5-12-11(8-10)15-13(20-12)9-17-6-2-1-3-7-17/h4-5,8,19H,1-3,6-7,9H2,(H,16,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 16n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443030
PNG
(N-hydroxy-2-(1-methyl-1H-pyrazol- 4-yl)-1-benzothi...)
Show SMILES Cn1cc(cn1)-c1cc2cc(ccc2s1)C(=O)NO
Show InChI InChI=1S/C13H11N3O2S/c1-16-7-10(6-14-16)12-5-9-4-8(13(17)15-18)2-3-11(9)19-12/h2-7,18H,1H3,(H,15,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 16n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM443106
PNG
(2-[2-fluoro-4-(6-methoxypyridin-3- yl)phenyl]-N-hy...)
Show SMILES COc1ccc(cn1)-c1ccc(-c2nc3cc(ccc3o2)C(=O)NO)c(F)c1
Show InChI InChI=1S/C20H14FN3O4/c1-27-18-7-4-13(10-22-18)11-2-5-14(15(21)8-11)20-23-16-9-12(19(25)24-26)3-6-17(16)28-20/h2-10,26H,1H3,(H,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
UniChem
US Patent
n/an/a 16n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...


US Patent US10654814 (2020)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 240 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%