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Patent code US10662156

Compile Data Set for Download or QSAR
Found 94 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444349
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1cccs1
Show InChI InChI=1S/C23H18Cl2N4O2S2/c24-18-7-3-16(4-8-18)20-12-15(13-27-22(20)17-5-9-19(25)10-6-17)14-28-23(26)29-33(30,31)21-2-1-11-32-21/h1-13H,14H2,(H3,26,28,29)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444338
PNG
(N-(amino(((6-(4-chlorophenyl)-5-(4-methoxyphenyl)p...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(CO)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H23ClN4O3S/c27-22-12-10-21(11-13-22)25-24(20-8-6-18(17-32)7-9-20)14-19(15-29-25)16-30-26(28)31-35(33,34)23-4-2-1-3-5-23/h1-15,32H,16-17H2,(H3,28,30,31)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444360
PNG
(N-((((5,6-bis(4-chlorophenyl)pyridin-3-yl)methyl)a...)
Show SMILES CN\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H22Cl2N4O2S/c1-29-26(32-35(33,34)23-5-3-2-4-6-23)31-17-18-15-24(19-7-11-21(27)12-8-19)25(30-16-18)20-9-13-22(28)14-10-20/h2-16H,17H2,1H3,(H2,29,31,32)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444325
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(4-methylphenyl)py...)
Show SMILES Cc1ccc(cc1)-c1ncc(CN\C(N)=N\S(=O)(=O)c2ccccc2)cc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C26H23ClN4O2S/c1-18-7-9-21(10-8-18)25-24(20-11-13-22(27)14-12-20)15-19(16-29-25)17-30-26(28)31-34(32,33)23-5-3-2-4-6-23/h2-16H,17H2,1H3,(H3,28,30,31)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444405
PNG
(N-(amino(((4,5-bis(4-chlorophenyl)pyrimidin-2-yl)m...)
Show SMILES N\C(NCc1ncc(-c2ccc(Cl)cc2)c(n1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C24H19Cl2N5O2S/c25-18-10-6-16(7-11-18)21-14-28-22(30-23(21)17-8-12-19(26)13-9-17)15-29-24(27)31-34(32,33)20-4-2-1-3-5-20/h1-14H,15H2,(H3,27,29,31)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444358
PNG
(N-((5,6-bis(4-chlorophenyl)pyridin-3-yl)methyl)-N&...)
Show SMILES NN\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H21Cl2N5O2S/c26-20-10-6-18(7-11-20)23-14-17(15-29-24(23)19-8-12-21(27)13-9-19)16-30-25(31-28)32-35(33,34)22-4-2-1-3-5-22/h1-15H,16,28H2,(H2,30,31,32)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444349
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1cccs1
Show InChI InChI=1S/C23H18Cl2N4O2S2/c24-18-7-3-16(4-8-18)20-12-15(13-27-22(20)17-5-9-19(25)10-6-17)14-28-23(26)29-33(30,31)21-2-1-11-32-21/h1-13H,14H2,(H3,26,28,29)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444351
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccco1
Show InChI InChI=1S/C23H18Cl2N4O3S/c24-18-7-3-16(4-8-18)20-12-15(13-27-22(20)17-5-9-19(25)10-6-17)14-28-23(26)29-33(30,31)21-2-1-11-32-21/h1-13H,14H2,(H3,26,28,29)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444406
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)-2-methoxypyridi...)
Show SMILES COc1nc(-c2ccc(Cl)cc2)c(cc1CN\C(N)=N\S(=O)(=O)c1ccccc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C26H22Cl2N4O3S/c1-35-25-19(16-30-26(29)32-36(33,34)22-5-3-2-4-6-22)15-23(17-7-11-20(27)12-8-17)24(31-25)18-9-13-21(28)14-10-18/h2-15H,16H2,1H3,(H3,29,30,32)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444359
PNG
(N-((((5,6-bis(4-chlorophenyl)pyridin-3-yl)methyl)a...)
Show SMILES ON\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20Cl2N4O3S/c26-20-10-6-18(7-11-20)23-14-17(15-28-24(23)19-8-12-21(27)13-9-19)16-29-25(30-32)31-35(33,34)22-4-2-1-3-5-22/h1-15,32H,16H2,(H2,29,30,31)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444409
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)-2-hydroxypyridi...)
Show SMILES N\C(NCc1cc(-c2ccc(Cl)cc2)c(nc1O)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20Cl2N4O3S/c26-19-10-6-16(7-11-19)22-14-18(24(32)30-23(22)17-8-12-20(27)13-9-17)15-29-25(28)31-35(33,34)21-4-2-1-3-5-21/h1-14H,15H2,(H,30,32)(H3,28,29,31)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444370
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES COc1cccc(c1)S(=O)(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C26H22Cl2N4O3S/c1-35-22-3-2-4-23(14-22)36(33,34)32-26(29)31-16-17-13-24(18-5-9-20(27)10-6-18)25(30-15-17)19-7-11-21(28)12-8-19/h2-15H,16H2,1H3,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444350
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccsc1
Show InChI InChI=1S/C23H18Cl2N4O2S2/c24-18-5-1-16(2-6-18)21-11-15(12-27-22(21)17-3-7-19(25)8-4-17)13-28-23(26)29-33(30,31)20-9-10-32-14-20/h1-12,14H,13H2,(H3,26,28,29)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444344
PNG
(N-(amino(((5-(4-methoxyphenyl)-6-(4-methylphenyl)p...)
Show SMILES Cc1ccc(cc1)-c1ncc(CN\C(N)=N\S(=O)(=O)c2ccccc2)cc1-c1ccc(CO)cc1
Show InChI InChI=1S/C27H26N4O3S/c1-19-7-11-23(12-8-19)26-25(22-13-9-20(18-32)10-14-22)15-21(16-29-26)17-30-27(28)31-35(33,34)24-5-3-2-4-6-24/h2-16,32H,17-18H2,1H3,(H3,28,30,31)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444352
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccoc1
Show InChI InChI=1S/C23H18Cl2N4O3S/c24-18-5-1-16(2-6-18)21-11-15(12-27-22(21)17-3-7-19(25)8-4-17)13-28-23(26)29-33(30,31)20-9-10-32-14-20/h1-12,14H,13H2,(H3,26,28,29)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444374
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccc(Cl)s1
Show InChI InChI=1S/C23H17Cl3N4O2S2/c24-17-5-1-15(2-6-17)19-11-14(12-28-22(19)16-3-7-18(25)8-4-16)13-29-23(27)30-34(31,32)21-10-9-20(26)33-21/h1-12H,13H2,(H3,27,29,30)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444354
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccccc1
Show InChI InChI=1S/C26H20Cl2N4O/c27-21-10-6-18(7-11-21)23-14-17(15-30-24(23)19-8-12-22(28)13-9-19)16-31-26(29)32-25(33)20-4-2-1-3-5-20/h1-15H,16H2,(H3,29,31,32,33)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444375
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1cc2ccccc2s1
Show InChI InChI=1S/C27H20Cl2N4O2S2/c28-21-9-5-18(6-10-21)23-13-17(15-31-26(23)19-7-11-22(29)12-8-19)16-32-27(30)33-37(34,35)25-14-20-3-1-2-4-24(20)36-25/h1-15H,16H2,(H3,30,32,33)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444371
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES CCOc1cccc(c1)S(=O)(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C27H24Cl2N4O3S/c1-2-36-23-4-3-5-24(15-23)37(34,35)33-27(30)32-17-18-14-25(19-6-10-21(28)11-7-19)26(31-16-18)20-8-12-22(29)13-9-20/h3-16H,2,17H2,1H3,(H3,30,32,33)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444327
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(4-cyanophenyl)pyr...)
Show SMILES N\C(NCc1cnc(-c2ccc(cc2)C#N)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H20ClN5O2S/c27-22-12-10-20(11-13-22)24-14-19(16-30-25(24)21-8-6-18(15-28)7-9-21)17-31-26(29)32-35(33,34)23-4-2-1-3-5-23/h1-14,16H,17H2,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444307
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20Cl2N4O2S/c26-20-10-6-18(7-11-20)23-14-17(15-29-24(23)19-8-12-21(27)13-9-19)16-30-25(28)31-34(32,33)22-4-2-1-3-5-22/h1-15H,16H2,(H3,28,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444307
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20Cl2N4O2S/c26-20-10-6-18(7-11-20)23-14-17(15-29-24(23)19-8-12-21(27)13-9-19)16-30-25(28)31-34(32,33)22-4-2-1-3-5-22/h1-15H,16H2,(H3,28,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444408
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)-2-methylpyridin...)
Show SMILES Cc1nc(-c2ccc(Cl)cc2)c(cc1CN\C(N)=N\S(=O)(=O)c1ccccc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C26H22Cl2N4O2S/c1-17-20(16-30-26(29)32-35(33,34)23-5-3-2-4-6-23)15-24(18-7-11-21(27)12-8-18)25(31-17)19-9-13-22(28)14-10-19/h2-15H,16H2,1H3,(H3,29,30,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444356
PNG
(N-(amino(((6-(4-chloro-2-fluorophenyl)-5-(4-chloro...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2F)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H19Cl2FN4O2S/c26-18-8-6-17(7-9-18)22-12-16(14-30-24(22)21-11-10-19(27)13-23(21)28)15-31-25(29)32-35(33,34)20-4-2-1-3-5-20/h1-14H,15H2,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444333
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(2-fluoro-4-methyl...)
Show SMILES Cc1ccc(c(F)c1)-c1ncc(CN\C(N)=N\S(=O)(=O)c2ccccc2)cc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C26H22ClFN4O2S/c1-17-7-12-22(24(28)13-17)25-23(19-8-10-20(27)11-9-19)14-18(15-30-25)16-31-26(29)32-35(33,34)21-5-3-2-4-6-21/h2-15H,16H2,1H3,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444307
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20Cl2N4O2S/c26-20-10-6-18(7-11-20)23-14-17(15-29-24(23)19-8-12-21(27)13-9-19)16-30-25(28)31-34(32,33)22-4-2-1-3-5-22/h1-15H,16H2,(H3,28,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444393
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)CCc1ccccc1
Show InChI InChI=1S/C28H24Cl2N4O/c29-23-11-7-21(8-12-23)25-16-20(17-32-27(25)22-9-13-24(30)14-10-22)18-33-28(31)34-26(35)15-6-19-4-2-1-3-5-19/h1-5,7-14,16-17H,6,15,18H2,(H3,31,33,34,35)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444330
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(4-(trifluorometho...)
Show SMILES N\C(NCc1cnc(-c2ccc(OC(F)(F)F)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H20ClF3N4O3S/c27-20-10-6-18(7-11-20)23-14-17(16-33-25(31)34-38(35,36)22-4-2-1-3-5-22)15-32-24(23)19-8-12-21(13-9-19)37-26(28,29)30/h1-15H,16H2,(H3,31,33,34)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444392
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)C1CCCCC1
Show InChI InChI=1S/C26H26Cl2N4O/c27-21-10-6-18(7-11-21)23-14-17(15-30-24(23)19-8-12-22(28)13-9-19)16-31-26(29)32-25(33)20-4-2-1-3-5-20/h6-15,20H,1-5,16H2,(H3,29,31,32,33)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444335
PNG
(N-(amino(((5-(3-chlorophenyl)-6-(4-chlorophenyl)py...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1cccc(Cl)c1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20Cl2N4O2S/c26-20-11-9-18(10-12-20)24-23(19-5-4-6-21(27)14-19)13-17(15-29-24)16-30-25(28)31-34(32,33)22-7-2-1-3-8-22/h1-15H,16H2,(H3,28,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444355
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1cccs1
Show InChI InChI=1S/C24H18Cl2N4OS/c25-18-7-3-16(4-8-18)20-12-15(13-28-22(20)17-5-9-19(26)10-6-17)14-29-24(27)30-23(31)21-2-1-11-32-21/h1-13H,14H2,(H3,27,29,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444346
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C25H19Cl2FN4O2S/c26-19-9-5-17(6-10-19)21-13-16(14-30-24(21)18-7-11-20(27)12-8-18)15-31-25(29)32-35(33,34)23-4-2-1-3-22(23)28/h1-14H,15H2,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444367
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1cccc(c1)C#N
Show InChI InChI=1S/C26H19Cl2N5O2S/c27-21-8-4-19(5-9-21)24-13-18(15-31-25(24)20-6-10-22(28)11-7-20)16-32-26(30)33-36(34,35)23-3-1-2-17(12-23)14-29/h1-13,15H,16H2,(H3,30,32,33)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444369
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES COc1ccccc1S(=O)(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C26H22Cl2N4O3S/c1-35-23-4-2-3-5-24(23)36(33,34)32-26(29)31-16-17-14-22(18-6-10-20(27)11-7-18)25(30-15-17)19-8-12-21(28)13-9-19/h2-15H,16H2,1H3,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444368
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C25H19Cl3N4O2S/c26-19-8-4-17(5-9-19)23-12-16(14-30-24(23)18-6-10-20(27)11-7-18)15-31-25(29)32-35(33,34)22-3-1-2-21(28)13-22/h1-14H,15H2,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444332
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(3-fluoro-4-methyl...)
Show SMILES Cc1ccc(cc1F)-c1ncc(CN\C(N)=N\S(=O)(=O)c2ccccc2)cc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C26H22ClFN4O2S/c1-17-7-8-20(14-24(17)28)25-23(19-9-11-21(27)12-10-19)13-18(15-30-25)16-31-26(29)32-35(33,34)22-5-3-2-4-6-22/h2-15H,16H2,1H3,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444390
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)C1CCCC1
Show InChI InChI=1S/C25H24Cl2N4O/c26-20-9-5-17(6-10-20)22-13-16(14-29-23(22)18-7-11-21(27)12-8-18)15-30-25(28)31-24(32)19-3-1-2-4-19/h5-14,19H,1-4,15H2,(H3,28,30,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444331
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(4-(trifluoromethy...)
Show SMILES N\C(NCc1cnc(-c2ccc(cc2)C(F)(F)F)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H20ClF3N4O2S/c27-21-12-8-18(9-13-21)23-14-17(15-32-24(23)19-6-10-20(11-7-19)26(28,29)30)16-33-25(31)34-37(35,36)22-4-2-1-3-5-22/h1-15H,16H2,(H3,31,33,34)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444394
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)Cc1ccccc1
Show InChI InChI=1S/C27H22Cl2N4O/c28-22-10-6-20(7-11-22)24-14-19(16-31-26(24)21-8-12-23(29)13-9-21)17-32-27(30)33-25(34)15-18-4-2-1-3-5-18/h1-14,16H,15,17H2,(H3,30,32,33,34)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444348
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C25H19Cl2FN4O2S/c26-19-5-1-17(2-6-19)23-13-16(14-30-24(23)18-3-7-20(27)8-4-18)15-31-25(29)32-35(33,34)22-11-9-21(28)10-12-22/h1-14H,15H2,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444407
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)-2-fluoropyridin...)
Show SMILES N\C(NCc1cc(-c2ccc(Cl)cc2)c(nc1F)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H19Cl2FN4O2S/c26-19-10-6-16(7-11-19)22-14-18(24(28)31-23(22)17-8-12-20(27)13-9-17)15-30-25(29)32-35(33,34)21-4-2-1-3-5-21/h1-14H,15H2,(H3,29,30,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444403
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)C1CCC(F)(F)CC1
Show InChI InChI=1S/C26H24Cl2F2N4O/c27-20-5-1-17(2-6-20)22-13-16(14-32-23(22)18-3-7-21(28)8-4-18)15-33-25(31)34-24(35)19-9-11-26(29,30)12-10-19/h1-8,13-14,19H,9-12,15H2,(H3,31,33,34,35)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444372
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccc(nc1)C#N
Show InChI InChI=1S/C25H18Cl2N6O2S/c26-19-5-1-17(2-6-19)23-11-16(13-31-24(23)18-3-7-20(27)8-4-18)14-32-25(29)33-36(34,35)22-10-9-21(12-28)30-15-22/h1-11,13,15H,14H2,(H3,29,32,33)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444381
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1nccs1
Show InChI InChI=1S/C23H17Cl2N5OS/c24-17-5-1-15(2-6-17)19-11-14(12-28-20(19)16-3-7-18(25)8-4-16)13-29-23(26)30-21(31)22-27-9-10-32-22/h1-12H,13H2,(H3,26,29,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444376
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)C1CCCCC1
Show InChI InChI=1S/C25H26Cl2N4O2S/c26-20-10-6-18(7-11-20)23-14-17(15-29-24(23)19-8-12-21(27)13-9-19)16-30-25(28)31-34(32,33)22-4-2-1-3-5-22/h6-15,22H,1-5,16H2,(H3,28,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444385
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES CCCCCC(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C25H26Cl2N4O/c1-2-3-4-5-23(32)31-25(28)30-16-17-14-22(18-6-10-20(26)11-7-18)24(29-15-17)19-8-12-21(27)13-9-19/h6-15H,2-5,16H2,1H3,(H3,28,30,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444382
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccc(cc1)C#N
Show InChI InChI=1S/C27H19Cl2N5O/c28-22-9-5-19(6-10-22)24-13-18(15-32-25(24)20-7-11-23(29)12-8-20)16-33-27(31)34-26(35)21-3-1-17(14-30)2-4-21/h1-13,15H,16H2,(H3,31,33,34,35)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444326
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(4-methoxyphenyl)p...)
Show SMILES N\C(NCc1cnc(-c2ccc(CO)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H23ClN4O3S/c27-22-12-10-20(11-13-22)24-14-19(15-29-25(24)21-8-6-18(17-32)7-9-21)16-30-26(28)31-35(33,34)23-4-2-1-3-5-23/h1-15,32H,16-17H2,(H3,28,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444377
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C24H24Cl2N4O2S/c25-19-9-5-17(6-10-19)22-13-16(14-28-23(22)18-7-11-20(26)12-8-18)15-29-24(27)30-33(31,32)21-3-1-2-4-21/h5-14,21H,1-4,15H2,(H3,27,29,30)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444347
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1cccc(F)c1
Show InChI InChI=1S/C25H19Cl2FN4O2S/c26-19-8-4-17(5-9-19)23-12-16(14-30-24(23)18-6-10-20(27)11-7-18)15-31-25(29)32-35(33,34)22-3-1-2-21(28)13-22/h1-14H,15H2,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444399
PNG
(1-((5,6-bis(4-chlorophenyl)pyridin-3-yl)methyl)-2-...)
Show SMILES CCOC(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H20Cl2N4O2/c1-2-30-22(29)28-21(25)27-13-14-11-19(15-3-7-17(23)8-4-15)20(26-12-14)16-5-9-18(24)10-6-16/h3-12H,2,13H2,1H3,(H3,25,27,28,29)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444366
PNG
(N-(amino((1-(5,6-bis(4-chlorophenyl)pyridin-3-yl)e...)
Show SMILES CC(N\C(N)=N\S(=O)(=O)c1ccccc1)c1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C26H22Cl2N4O2S/c1-17(31-26(29)32-35(33,34)23-5-3-2-4-6-23)20-15-24(18-7-11-21(27)12-8-18)25(30-16-20)19-9-13-22(28)14-10-19/h2-17H,1H3,(H3,29,31,32)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444391
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)C1CC1
Show InChI InChI=1S/C23H20Cl2N4O/c24-18-7-3-15(4-8-18)20-11-14(13-28-23(26)29-22(30)17-1-2-17)12-27-21(20)16-5-9-19(25)10-6-16/h3-12,17H,1-2,13H2,(H3,26,28,29,30)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444388
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccsc1
Show InChI InChI=1S/C24H18Cl2N4OS/c25-19-5-1-16(2-6-19)21-11-15(12-28-22(21)17-3-7-20(26)8-4-17)13-29-24(27)30-23(31)18-9-10-32-14-18/h1-12,14H,13H2,(H3,27,29,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444384
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES CCCC(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H22Cl2N4O/c1-2-3-21(30)29-23(26)28-14-15-12-20(16-4-8-18(24)9-5-16)22(27-13-15)17-6-10-19(25)11-7-17/h4-13H,2-3,14H2,1H3,(H3,26,28,29,30)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444337
PNG
(N-(amino(((6-(4-chlorophenyl)-5-(4-methylphenyl)py...)
Show SMILES Cc1ccc(cc1)-c1cc(CN\C(N)=N\S(=O)(=O)c2ccccc2)cnc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C26H23ClN4O2S/c1-18-7-9-20(10-8-18)24-15-19(16-29-25(24)21-11-13-22(27)14-12-21)17-30-26(28)31-34(32,33)23-5-3-2-4-6-23/h2-16H,17H2,1H3,(H3,28,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444383
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES COCC(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H20Cl2N4O2/c1-30-13-20(29)28-22(25)27-12-14-10-19(15-2-6-17(23)7-3-15)21(26-11-14)16-4-8-18(24)9-5-16/h2-11H,12-13H2,1H3,(H3,25,27,28,29)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444387
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccccc1F
Show InChI InChI=1S/C26H19Cl2FN4O/c27-19-9-5-17(6-10-19)22-13-16(14-31-24(22)18-7-11-20(28)12-8-18)15-32-26(30)33-25(34)21-3-1-2-4-23(21)29/h1-14H,15H2,(H3,30,32,33,34)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444361
PNG
(1-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES NC(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C20H17Cl2N5O/c21-15-5-1-13(2-6-15)17-9-12(11-26-19(23)27-20(24)28)10-25-18(17)14-3-7-16(22)8-4-14/h1-10H,11H2,(H5,23,24,26,27,28)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444334
PNG
(N-(amino(((6-(4-chlorophenyl)-5-phenylpyridin-3-yl...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccccc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H21ClN4O2S/c26-21-13-11-20(12-14-21)24-23(19-7-3-1-4-8-19)15-18(16-28-24)17-29-25(27)30-33(31,32)22-9-5-2-6-10-22/h1-16H,17H2,(H3,27,29,30)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444323
PNG
(N-(amino(((5-(4-chlorophenyl)-6-phenylpyridin-3-yl...)
Show SMILES N\C(NCc1cnc(-c2ccccc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H21ClN4O2S/c26-21-13-11-19(12-14-21)23-15-18(16-28-24(23)20-7-3-1-4-8-20)17-29-25(27)30-33(31,32)22-9-5-2-6-10-22/h1-16H,17H2,(H3,27,29,30)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444378
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)C1CC1
Show InChI InChI=1S/C22H20Cl2N4O2S/c23-17-5-1-15(2-6-17)20-11-14(12-26-21(20)16-3-7-18(24)8-4-16)13-27-22(25)28-31(29,30)19-9-10-19/h1-8,11-12,19H,9-10,13H2,(H3,25,27,28)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444400
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccccn1
Show InChI InChI=1S/C25H19Cl2N5O/c26-19-8-4-17(5-9-19)21-13-16(14-30-23(21)18-6-10-20(27)11-7-18)15-31-25(28)32-24(33)22-3-1-2-12-29-22/h1-14H,15H2,(H3,28,31,32,33)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444342
PNG
(N-(amino(((6-(4-chlorophenyl)-5-(4-(trifluorometho...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(OC(F)(F)F)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H20ClF3N4O3S/c27-20-10-6-19(7-11-20)24-23(18-8-12-21(13-9-18)37-26(28,29)30)14-17(15-32-24)16-33-25(31)34-38(35,36)22-4-2-1-3-5-22/h1-15H,16H2,(H3,31,33,34)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444379
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C26H22Cl2N4O2S/c27-22-10-6-20(7-11-22)24-14-19(15-30-25(24)21-8-12-23(28)13-9-21)16-31-26(29)32-35(33,34)17-18-4-2-1-3-5-18/h1-15H,16-17H2,(H3,29,31,32)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444397
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccco1
Show InChI InChI=1S/C24H18Cl2N4O2/c25-18-7-3-16(4-8-18)20-12-15(13-28-22(20)17-5-9-19(26)10-6-17)14-29-24(27)30-23(31)21-2-1-11-32-21/h1-13H,14H2,(H3,27,29,30,31)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444389
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES COc1ccc(cc1)C(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C27H22Cl2N4O2/c1-35-23-12-6-20(7-13-23)26(34)33-27(30)32-16-17-14-24(18-2-8-21(28)9-3-18)25(31-15-17)19-4-10-22(29)11-5-19/h2-15H,16H2,1H3,(H3,30,32,33,34)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444396
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C27H19Cl2F3N4O/c28-21-9-3-17(4-10-21)23-13-16(14-34-24(23)18-5-11-22(29)12-6-18)15-35-26(33)36-25(37)19-1-7-20(8-2-19)27(30,31)32/h1-14H,15H2,(H3,33,35,36,37)
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Toray Industries, Inc.

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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444354
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccccc1
Show InChI InChI=1S/C26H20Cl2N4O/c27-21-10-6-18(7-11-21)23-14-17(15-30-24(23)19-8-12-22(28)13-9-19)16-31-26(29)32-25(33)20-4-2-1-3-5-20/h1-15H,16H2,(H3,29,31,32,33)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444404
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES CC(C)(C(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C29H26Cl2N4O/c1-29(2,22-6-4-3-5-7-22)27(36)35-28(32)34-18-19-16-25(20-8-12-23(30)13-9-20)26(33-17-19)21-10-14-24(31)15-11-21/h3-17H,18H2,1-2H3,(H3,32,34,35,36)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444415
PNG
(N-(amino(((6-(4-chloro-2-hydroxyphenyl)-5-(4-chlor...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2O)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20Cl2N4O3S/c26-18-8-6-17(7-9-18)22-12-16(14-29-24(22)21-11-10-19(27)13-23(21)32)15-30-25(28)31-35(33,34)20-4-2-1-3-5-20/h1-14,32H,15H2,(H3,28,30,31)
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Toray Industries, Inc.

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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444401
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1cscn1
Show InChI InChI=1S/C23H17Cl2N5OS/c24-17-5-1-15(2-6-17)19-9-14(10-27-21(19)16-3-7-18(25)8-4-16)11-28-23(26)30-22(31)20-12-32-13-29-20/h1-10,12-13H,11H2,(H3,26,28,30,31)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444413
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(4-hydroxyphenyl)p...)
Show SMILES N\C(NCc1cnc(-c2ccc(O)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H21ClN4O3S/c26-20-10-6-18(7-11-20)23-14-17(15-28-24(23)19-8-12-21(31)13-9-19)16-29-25(27)30-34(32,33)22-4-2-1-3-5-22/h1-15,31H,16H2,(H3,27,29,30)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444341
PNG
(N-(amino(((6-(4-chlorophenyl)-5-(4-(trifluoromethy...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(cc1)C(F)(F)F)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H20ClF3N4O2S/c27-21-12-8-19(9-13-21)24-23(18-6-10-20(11-7-18)26(28,29)30)14-17(15-32-24)16-33-25(31)34-37(35,36)22-4-2-1-3-5-22/h1-15H,16H2,(H3,31,33,34)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444410
PNG
(N-(amino(((6-phenyl-5-(4-(trifluoromethyl)phenyl)p...)
Show SMILES N\C(NCc1cnc(-c2ccccc2)c(c1)-c1ccc(cc1)C(F)(F)F)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H21F3N4O2S/c27-26(28,29)21-13-11-19(12-14-21)23-15-18(16-31-24(23)20-7-3-1-4-8-20)17-32-25(30)33-36(34,35)22-9-5-2-6-10-22/h1-16H,17H2,(H3,30,32,33)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444411
PNG
(N-(amino(((5-phenyl-6-(4-(trifluoromethyl)phenyl)p...)
Show SMILES N\C(NCc1cnc(-c2ccc(cc2)C(F)(F)F)c(c1)-c1ccccc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H21F3N4O2S/c27-26(28,29)21-13-11-20(12-14-21)24-23(19-7-3-1-4-8-19)15-18(16-31-24)17-32-25(30)33-36(34,35)22-9-5-2-6-10-22/h1-16H,17H2,(H3,30,32,33)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444340
PNG
(N-(amino(((6-(4-chlorophenyl)-5-(4-fluorophenyl)py...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(F)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20ClFN4O2S/c26-20-10-6-19(7-11-20)24-23(18-8-12-21(27)13-9-18)14-17(15-29-24)16-30-25(28)31-34(32,33)22-4-2-1-3-5-22/h1-15H,16H2,(H3,28,30,31)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444386
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C26H19Cl2FN4O/c27-20-7-1-17(2-8-20)23-13-16(14-31-24(23)18-3-9-21(28)10-4-18)15-32-26(30)33-25(34)19-5-11-22(29)12-6-19/h1-14H,15H2,(H3,30,32,33,34)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444357
PNG
(N-(amino(((6-(4-chlorophenyl)-5-(3-fluoro-4-methox...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(CO)c(F)c1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H22ClFN4O3S/c27-21-10-8-18(9-11-21)25-23(19-6-7-20(16-33)24(28)13-19)12-17(14-30-25)15-31-26(29)32-36(34,35)22-4-2-1-3-5-22/h1-14,33H,15-16H2,(H3,29,31,32)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444328
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(4-fluorophenyl)py...)
Show SMILES N\C(NCc1cnc(-c2ccc(F)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20ClFN4O2S/c26-20-10-6-18(7-11-20)23-14-17(15-29-24(23)19-8-12-21(27)13-9-19)16-30-25(28)31-34(32,33)22-4-2-1-3-5-22/h1-15H,16H2,(H3,28,30,31)
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Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444380
PNG
(((2-amino-2-(((5,6-bis(4-chlorophenyl)pyridin-3-yl...)
Show SMILES CN(C)S(=O)(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H21Cl2N5O2S/c1-28(2)31(29,30)27-21(24)26-13-14-11-19(15-3-7-17(22)8-4-15)20(25-12-14)16-5-9-18(23)10-6-16/h3-12H,13H2,1-2H3,(H3,24,26,27)
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Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444402
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)CC(F)(F)F
Show InChI InChI=1S/C22H17Cl2F3N4O/c23-16-5-1-14(2-6-16)18-9-13(11-29-20(18)15-3-7-17(24)8-4-15)12-30-21(28)31-19(32)10-22(25,26)27/h1-9,11H,10,12H2,(H3,28,30,31,32)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444324
PNG
(N-(amino(((6-(3-chlorophenyl)-5-(4-chlorophenyl)py...)
Show SMILES N\C(NCc1cnc(-c2cccc(Cl)c2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20Cl2N4O2S/c26-20-11-9-18(10-12-20)23-13-17(15-29-24(23)19-5-4-6-21(27)14-19)16-30-25(28)31-34(32,33)22-7-2-1-3-8-22/h1-15H,16H2,(H3,28,30,31)
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US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444395
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/C(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C26H19Cl3N4O/c27-20-7-1-17(2-8-20)23-13-16(14-31-24(23)18-3-9-21(28)10-4-18)15-32-26(30)33-25(34)19-5-11-22(29)12-6-19/h1-14H,15H2,(H3,30,32,33,34)
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n/an/a 1.51E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444339
PNG
(N-(amino(((6-(4-chlorophenyl)-5-(4-cyanophenyl)pyr...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(cc1)C#N)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H20ClN5O2S/c27-22-12-10-21(11-13-22)25-24(20-8-6-18(15-28)7-9-20)14-19(16-30-25)17-31-26(29)32-35(33,34)23-4-2-1-3-5-23/h1-14,16H,17H2,(H3,29,31,32)
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n/an/a 1.52E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444412
PNG
(N-(amino(((6-(4-chlorophenyl)-5-(4-hydroxyphenyl)p...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(O)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H21ClN4O3S/c26-20-10-6-19(7-11-20)24-23(18-8-12-21(31)13-9-18)14-17(15-28-24)16-29-25(27)30-34(32,33)22-4-2-1-3-5-22/h1-15,31H,16H2,(H3,27,29,30)
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n/an/a 1.61E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444329
PNG
(N-(amino(((5-(4-chlorophenyl)-6-(3-fluorophenyl)py...)
Show SMILES N\C(NCc1cnc(-c2cccc(F)c2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20ClFN4O2S/c26-20-11-9-18(10-12-20)23-13-17(15-29-24(23)19-5-4-6-21(27)14-19)16-30-25(28)31-34(32,33)22-7-2-1-3-8-22/h1-15H,16H2,(H3,28,30,31)
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n/an/a 1.71E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444343
PNG
(N-(amino(((6-(4-chlorophenyl)-5-(4-isopropoxypheny...)
Show SMILES CC(C)Oc1ccc(cc1)-c1cc(CN\C(N)=N\S(=O)(=O)c2ccccc2)cnc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C28H27ClN4O3S/c1-19(2)36-24-14-10-21(11-15-24)26-16-20(17-31-27(26)22-8-12-23(29)13-9-22)18-32-28(30)33-37(34,35)25-6-4-3-5-7-25/h3-17,19H,18H2,1-2H3,(H3,30,32,33)
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n/an/a 1.73E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444345
PNG
(N-(amino(((6-(4-methylphenyl)-5-(4-(trifluoromethy...)
Show SMILES Cc1ccc(cc1)-c1ncc(CN\C(N)=N\S(=O)(=O)c2ccccc2)cc1-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C27H23F3N4O2S/c1-18-7-9-21(10-8-18)25-24(20-11-13-22(14-12-20)27(28,29)30)15-19(16-32-25)17-33-26(31)34-37(35,36)23-5-3-2-4-6-23/h2-16H,17H2,1H3,(H3,31,33,34)
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n/an/a 1.84E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444398
PNG
(3-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES CN(C)C(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H21Cl2N5O/c1-29(2)22(30)28-21(25)27-13-14-11-19(15-3-7-17(23)8-4-15)20(26-12-14)16-5-9-18(24)10-6-16/h3-12H,13H2,1-2H3,(H3,25,27,28,30)
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n/an/a 1.88E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444373
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES Cn1cc(cn1)S(=O)(=O)\N=C(/N)NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H20Cl2N6O2S/c1-31-14-20(13-29-31)34(32,33)30-23(26)28-12-15-10-21(16-2-6-18(24)7-3-16)22(27-11-15)17-4-8-19(25)9-5-17/h2-11,13-14H,12H2,1H3,(H3,26,28,30)
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n/an/a 2.01E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444353
PNG
(N-(amino(((6-(4-methylphenyl)-5-(4-(trifluoromethy...)
Show SMILES Cc1ccc(cc1)-c1ncc(CN\C(N)=N\S(=O)(=O)c2cccs2)cc1-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C25H21F3N4O2S2/c1-16-4-6-19(7-5-16)23-21(18-8-10-20(11-9-18)25(26,27)28)13-17(14-30-23)15-31-24(29)32-36(33,34)22-3-2-12-35-22/h2-14H,15H2,1H3,(H3,29,31,32)
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n/an/a 2.07E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444414
PNG
(N-(amino(((5,6-bis(4-chlorophenyl)pyridin-3-yl)met...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccc(Cl)cc1)=N/S(=O)(=O)c1cccc(O)c1
Show InChI InChI=1S/C25H20Cl2N4O3S/c26-19-8-4-17(5-9-19)23-12-16(14-29-24(23)18-6-10-20(27)11-7-18)15-30-25(28)31-35(33,34)22-3-1-2-21(32)13-22/h1-14,32H,15H2,(H3,28,30,31)
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n/an/a 2.14E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))
BDBM444336
PNG
(N-(amino(((5-(2-chlorophenyl)-6-(4-chlorophenyl)py...)
Show SMILES N\C(NCc1cnc(-c2ccc(Cl)cc2)c(c1)-c1ccccc1Cl)=N/S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H20Cl2N4O2S/c26-19-12-10-18(11-13-19)24-22(21-8-4-5-9-23(21)27)14-17(15-29-24)16-30-25(28)31-34(32,33)20-6-2-1-3-7-20/h1-15H,16H2,(H3,28,30,31)
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n/an/a 2.41E+3n/an/an/an/an/an/a



Toray Industries, Inc.

US Patent


Assay Description
Full-length cDNA of human MALT1 gene (GenBank accession No: AB026118.1) amplified by PCR was inserted in flame to a SalI site located downstream of G...


US Patent US10662156 (2020)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%