Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 9139
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM444830(2-(((1r,4r)-4-((3-(3- chlorophenyl)-3- phenylureid...)
Affinity DataEC50:  61.1nMAssay Description:Compounds were screened for agonists of the human prostacyclin (PGI2) receptor using the HTRF assay for direct cAMP measurement (Gabriel et al., ASSA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM444835(2-(((1r,4r)-4-(((3- fluorophenyl)(5-methylthiophen...)
Affinity DataEC50:  19.1nMAssay Description:Compounds were screened for agonists of the human prostacyclin (PGI2) receptor using the HTRF assay for direct cAMP measurement (Gabriel et al., ASSA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM50235379(CHEMBL3932106 | US10668033, Compound 55)
Affinity DataEC50:  5.14nMAssay Description:Compounds were screened for agonists of the human prostacyclin (PGI2) receptor using the HTRF assay for direct cAMP measurement (Gabriel et al., ASSA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM444831(2-(((1s,4s)-4-(((4- fluorophenyl)(phenyl) carbamoy...)
Affinity DataEC50:  56.9nMAssay Description:Compounds were screened for agonists of the human prostacyclin (PGI2) receptor using the HTRF assay for direct cAMP measurement (Gabriel et al., ASSA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent