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Patent code US10676460

Compile Data Set for Download or QSAR
Found 56 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calmodulin/Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 50n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Axin-1/Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.15E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 1.01E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 8


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 1.19E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 1.76E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 1.76E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 1.78E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 1.87E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 1.92E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 2.38E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 2.39E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Casein kinase II subunit alpha'


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 2.55E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 3.38E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 3.38E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Aurora kinase A/B


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 3.98E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Aurora-A


(Mus musculus (mouse))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 3.98E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Nuclear receptor subfamily 2 group C member 2


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit epsilon


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit epsilon


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Cyclin-dependent kinase 2


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase TXK


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Axin-1/Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Serine/threonine-protein kinase TBK1


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Cytoplasmic tyrosine-protein kinase BMX


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Cyclin-dependent kinase 5 regulatory subunit 1


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 1


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Casein kinase II subunit alpha'


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Casein kinase II subunit alpha


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Aurora kinase A/B


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Cyclin-dependent kinase 2


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1, p25


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 1


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Homo sapiens (Human))
BDBM357015
PNG
(US10214511, Example 19 | US10676460, Example 19)
Show SMILES Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C20H15ClN4/c21-20-24-17-11-6-10-16(14-7-2-1-3-8-14)18(17)19(25-20)23-13-15-9-4-5-12-22-15/h1-12H,13H2,(H,23,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Cytoplasmic tyrosine-protein kinase BMX


(Homo sapiens (Human))
BDBM50239227
PNG
(CHEMBL4094440 | US10214511, Example 7 | US10676460...)
Show SMILES NS(=O)(=O)c1cncc(c1)-c1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Show InChI InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Cyclin-dependent kinase 2


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
Axin-1/Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50239229
PNG
(CHEMBL4097255 | US10676460, Example 1)
Show SMILES C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncnc1)c1ccccn1
Show InChI InChI=1S/C24H18N6/c1-2-7-17(8-3-1)20-10-6-11-21-22(20)24(28-15-19-9-4-5-12-27-19)30-23(29-21)18-13-25-16-26-14-18/h1-14,16H,15H2,(H,28,29,30)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...


US Patent US10676460 (2020)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%