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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449375 (N-[[4-[(1-tetrahydropyran-4- yl-4- piperidyl)sulfi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 2.02 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449131 (Imidazo[1,2-a]pyridine-6- carboxylic acid 4-[4-(4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449216 (N-[[4-[(6-methyl-2,6- diazaspiro[3.4]octan-2- yl)s...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 2.83 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449216 (N-[[4-[(6-methyl-2,6- diazaspiro[3.4]octan-2- yl)s...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 2.83 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449374 (N-[[4-[[1-(2,2,2- tnfluoroethyl)-4- piperidyl]sulf...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 2.93 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449095 (US10696692, Example 73 | US10696692, Example 74 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449132 (Imidazo[1,2-a]pyridine-6- carboxylic acid 4-[4-(4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM50438962 (CHEMBL2420637 | US10696692, Example 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449086 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449086 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 3.72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449100 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449100 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449140 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449140 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 4.13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449142 (Thieno[2,3-c]pyridine-2- carboxylic acid 4-(1- oxe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 4.27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449142 (Thieno[2,3-c]pyridine-2- carboxylic acid 4-(1- oxe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449141 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(4- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449048 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(8- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449181 (Imidazo[1,2-a]pyridine-6- carboxylic acid 4-(3-aza...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449201 (Furo[2,3-c]pyridine-2- carboxylic acid 4-(1- isobu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PDB UniChem | PDB US Patent | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449095 (US10696692, Example 73 | US10696692, Example 74 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449108 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449108 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 5.12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449133 (Imidazo[1,2-a]pyridine-6- carboxylic acid 4-(3- tr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449143 (9-(4-{[(Imidazo[1,2- a]pyridine-6-carbonyl)- amino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449066 (Thieno[2,3-c]pyridine-2- carboxylic acid 4- ((1R,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449386 (N-[[4-[[1-(2,2,2- tnfluoroethyl)-4- piperidyl]sulf...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 5.82 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449261 (US10696692, Example 242 | tert-butyl 2-[4-[(imidaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 6.34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449092 (US10696692, Example 70 | cis-Imidazo[1,2- a]pyridi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449127 (Imidazo[1,2-a]pyridine-6-carboxylic acid 4-[4-(2- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449037 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4- (mo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449265 (N-[[4-[3-(4-methylpiperazine- 1-carbonyl)azetidin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 7.03 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449201 (Furo[2,3-c]pyridine-2- carboxylic acid 4-(1- isobu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PDB UniChem | PDB US Patent | n/a | n/a | 7.23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM50439318 (CHEMBL2419536 | US10696692, Example 292) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449051 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(4- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449200 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449200 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(1- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449054 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-(3- ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449077 (US10696692, Example 55 | [1-(4-{[(lmodazo[1,2- a]p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449105 (Imidazo[1,2-a]pyridine-6- carboxylic acid 4- [(3R,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM50060826 (CHEMBL3394721 | US10696692, Example 205) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449185 (US10696692, Example 164 | cis-Imidazo[1,2- alpyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449238 (N-[[4-(1-oxa-7- azaspiro[4.4]nonan-7- ylsulfonyl)p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 8.45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449043 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4- (te...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 8.65 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449043 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4- (te...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449286 (N-[[4-[(6,6-difluoro-2- azaspiro[3.3]heptan-2- yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 8.77 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449102 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[(R)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 8.88 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449102 (Imidazo[1,2-a]pyrimidine- 6-carboxylic acid 4-[(R)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449204 (8-(4-{[(Imidazo[1,2- a]pyridine-6-carbonyl)- amino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | UniChem | US Patent | n/a | n/a | 8.99 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Nicotinamide phosphoribosyltransferase (Homo sapiens (Human)) | BDBM449201 (Furo[2,3-c]pyridine-2- carboxylic acid 4-(1- isobu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PDB UniChem | PDB US Patent | n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US10696692 (2020) | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Displayed 1 to 50 (of 374 total ) | Next | Last >> |
