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Patent code US10703755

Compile Data Set for Download or QSAR

Found 351 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450193
PNG
(US10703755, Example 393 | US10703755, Example 403)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)[C@H]3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)19-9-20(27)12-29-11-19)13-18-4-3-17(10-22(18)28)21-14-33-7-5-16(21)6-8-33/h3-4,9-12,16,21H,5-8,13-14H2,1-2H3/t21-/m0/s1
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n/an/a 1n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450104
PNG
(US10703755, Example 285)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@@H]4C[C@@H]5CC[C@H](C4)N5C)cc3F)c2n1
Show InChI InChI=1S/C27H28F2N6O2/c1-15-24-26(33-27(31-15)36-3)35(25(32-24)17-8-18(28)13-30-12-17)14-16-4-7-21(11-23(16)29)37-22-9-19-5-6-20(10-22)34(19)2/h4,7-8,11-13,19-20,22H,5-6,9-10,14H2,1-3H3/t19-,20+,22+
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n/an/a 2n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450060
PNG
(9-{4-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]benzyl}-8-(...)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)[C@H]3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-3-5-18(6-4-17)22-15-32-9-7-19(22)8-10-32/h3-6,11-13,19,22H,7-10,14-15H2,1-2H3/t22-/m1/s1
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SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450103
PNG
(US10703755, Example 284)
Show SMILES CCN1CCC(CC1)c1ccc(Cn2c(nc3c(C)nc(OC)nc23)-c2cncc(F)c2)c(F)c1
Show InChI InChI=1S/C26H28F2N6O/c1-4-33-9-7-17(8-10-33)18-5-6-19(22(28)12-18)15-34-24(20-11-21(27)14-29-13-20)31-23-16(2)30-26(35-3)32-25(23)34/h5-6,11-14,17H,4,7-10,15H2,1-3H3
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SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450055
PNG
(US10703755, Example 172)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C27H28F2N6O/c1-3-36-27-31-16(2)24-26(33-27)35(25(32-24)20-10-21(28)13-30-12-20)14-19-5-4-18(11-23(19)29)22-15-34-8-6-17(22)7-9-34/h4-5,10-13,17,22H,3,6-9,14-15H2,1-2H3
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SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450099
PNG
(US10703755, Example 280)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5C)cc3F)c2n1
Show InChI InChI=1S/C26H27F2N7O/c1-15-23-25(32-26(30-15)36-3)35(24(31-23)18-7-19(27)10-29-9-18)12-17-5-4-16(6-22(17)28)11-34-14-20-8-21(34)13-33(20)2/h4-7,9-10,20-21H,8,11-14H2,1-3H3/t20-,21-/m0/s1
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n/an/a 3n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450121
PNG
(US10703755, Example 304)
Show SMILES COc1nc(C)c2nc(-c3cnccc3C)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C27H29FN6O/c1-16-6-9-29-13-21(16)25-31-24-17(2)30-27(35-3)32-26(24)34(25)14-20-5-4-19(12-23(20)28)22-15-33-10-7-18(22)8-11-33/h4-6,9,12-13,18,22H,7-8,10-11,14-15H2,1-3H3
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n/an/a 4n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450122
PNG
(US10703755, Example 305)
Show SMILES COc1nc(C)c2nc(-c3cncc(C)c3)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C27H29FN6O/c1-16-10-21(13-29-12-16)25-31-24-17(2)30-27(35-3)32-26(24)34(25)14-20-5-4-19(11-23(20)28)22-15-33-8-6-18(22)7-9-33/h4-5,10-13,18,22H,6-9,14-15H2,1-3H3
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n/an/a 5n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450195
PNG
(US10703755, Example 395)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc([C@H]4CN5CCC4CC5)c(c3)C#N)c2n1
Show InChI InChI=1S/C28H28FN7O/c1-3-37-28-32-17(2)25-27(34-28)36(26(33-25)21-11-22(29)14-31-13-21)15-18-4-5-23(20(10-18)12-30)24-16-35-8-6-19(24)7-9-35/h4-5,10-11,13-14,19,24H,3,6-9,15-16H2,1-2H3/t24-/m0/s1
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n/an/a 5n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM449992
PNG
(US10703755, Example 110)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@H]5C[C@@H]4CN5C)cc3)c2n1
Show InChI InChI=1S/C27H30FN7O/c1-4-36-27-30-17(2)24-26(32-27)35(25(31-24)20-9-21(28)12-29-11-20)14-19-7-5-18(6-8-19)13-34-16-22-10-23(34)15-33(22)3/h5-9,11-12,22-23H,4,10,13-16H2,1-3H3/t22-,23-/m1/s1
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n/an/a 5n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450208
PNG
(US10703755, Example 412)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@@H]4CN5CCC4CC5)cc3F)c2n1
Show InChI InChI=1S/C26H26F2N6O2/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)18-9-19(27)12-29-11-18)13-17-3-4-20(10-21(17)28)36-22-14-33-7-5-16(22)6-8-33/h3-4,9-12,16,22H,5-8,13-14H2,1-2H3/t22-/m1/s1
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SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450201
PNG
(US10703755, Example 401)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc([C@H]4CN5CCC4CC5)c(c3)C#N)c2n1
Show InChI InChI=1S/C27H26FN7O/c1-16-24-26(33-27(31-16)36-2)35(25(32-24)20-10-21(28)13-30-12-20)14-17-3-4-22(19(9-17)11-29)23-15-34-7-5-18(23)6-8-34/h3-4,9-10,12-13,18,23H,5-8,14-15H2,1-2H3/t23-/m0/s1
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n/an/a 6n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450014
PNG
(US10703755, Example 131)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5CC)cc3)c2n1
Show InChI InChI=1S/C28H32FN7O/c1-4-34-16-24-11-23(34)17-35(24)14-19-6-8-20(9-7-19)15-36-26(21-10-22(29)13-30-12-21)32-25-18(3)31-28(37-5-2)33-27(25)36/h6-10,12-13,23-24H,4-5,11,14-17H2,1-3H3/t23-,24-/m0/s1
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n/an/a 7n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450135
PNG
(US10703755, Example 318)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(C4CN5CCC4CC5)c(c3)C#N)c2n1
Show InChI InChI=1S/C27H26FN7O/c1-16-24-26(33-27(31-16)36-2)35(25(32-24)20-10-21(28)13-30-12-20)14-17-3-4-22(19(9-17)11-29)23-15-34-7-5-18(23)6-8-34/h3-4,9-10,12-13,18,23H,5-8,14-15H2,1-2H3
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SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450120
PNG
(US10703755, Example 303)
Show SMILES COc1nc(C)c2nc(-c3cccnc3)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)19-4-3-9-28-13-19)14-20-6-5-18(12-22(20)27)21-15-32-10-7-17(21)8-11-32/h3-6,9,12-13,17,21H,7-8,10-11,14-15H2,1-2H3
PDB

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SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450133
PNG
(US10703755, Example 316)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(C4CN5CCC4CC5)c(c3)C#N)c2n1
Show InChI InChI=1S/C28H28FN7O/c1-3-37-28-32-17(2)25-27(34-28)36(26(33-25)21-11-22(29)14-31-13-21)15-18-4-5-23(20(10-18)12-30)24-16-35-8-6-19(24)7-9-35/h4-5,10-11,13-14,19,24H,3,6-9,15-16H2,1-2H3
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SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450052
PNG
(US10703755, Example 169)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C27H29FN6O/c1-3-35-27-30-17(2)24-26(32-27)34(25(31-24)21-12-22(28)14-29-13-21)15-18-4-6-19(7-5-18)23-16-33-10-8-20(23)9-11-33/h4-7,12-14,20,23H,3,8-11,15-16H2,1-2H3
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SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450179
PNG
(US10703755, Example 377)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(C4CN5CCC4CC5)c(F)c3)c2n1
Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)18-10-19(27)12-29-11-18)13-16-3-4-20(22(28)9-16)21-14-33-7-5-17(21)6-8-33/h3-4,9-12,17,21H,5-8,13-14H2,1-2H3
PDB

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n/an/a 7n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450223
PNG
(US10703755, Example 431)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CCNCC3)c2n1
Show InChI InChI=1S/C24H24F2N6O/c1-14-21-23(31-24(29-14)33-2)32(22(30-21)18-9-19(25)12-28-11-18)13-17-4-3-16(10-20(17)26)15-5-7-27-8-6-15/h3-4,9-12,15,27H,5-8,13H2,1-2H3
PDB

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n/an/a 8n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450131
PNG
(US10703755, Example 314)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)19-9-20(27)12-29-11-19)13-18-4-3-17(10-22(18)28)21-14-33-7-5-16(21)6-8-33/h3-4,9-12,16,21H,5-8,13-14H2,1-2H3
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n/an/a 8n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450101
PNG
(US10703755, Example 282)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CCN(C)CC3)c2n1
Show InChI InChI=1S/C25H26F2N6O/c1-15-22-24(31-25(29-15)34-3)33(23(30-22)19-10-20(26)13-28-12-19)14-18-5-4-17(11-21(18)27)16-6-8-32(2)9-7-16/h4-5,10-13,16H,6-9,14H2,1-3H3
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n/an/a 8n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450130
PNG
(US10703755, Example 313)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4CC5CC4CN5C)cc3F)c2n1
Show InChI InChI=1S/C27H29F2N7O/c1-4-37-27-31-16(2)24-26(33-27)36(25(32-24)19-8-20(28)11-30-10-19)13-18-6-5-17(7-23(18)29)12-35-15-21-9-22(35)14-34(21)3/h5-8,10-11,21-22H,4,9,12-15H2,1-3H3
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n/an/a 8n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450209
PNG
(US10703755, Example 413)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@H]4CN5CCC4CC5)cc3F)c2n1
Show InChI InChI=1S/C26H26F2N6O2/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)18-9-19(27)12-29-11-18)13-17-3-4-20(10-21(17)28)36-22-14-33-7-5-16(22)6-8-33/h3-4,9-12,16,22H,5-8,13-14H2,1-2H3/t22-/m0/s1
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n/an/a 9n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450225
PNG
(US10703755, Example 433)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@@H]4C[C@@H]5CC[C@H](C4)N5)cc3F)c2n1
Show InChI InChI=1S/C26H26F2N6O2/c1-14-23-25(33-26(30-14)35-2)34(24(32-23)16-7-17(27)12-29-11-16)13-15-3-6-20(10-22(15)28)36-21-8-18-4-5-19(9-21)31-18/h3,6-7,10-12,18-19,21,31H,4-5,8-9,13H2,1-2H3/t18-,19+,21+
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n/an/a 9n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM449991
PNG
(US10703755, Example 109)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5C)cc3)c2n1
Show InChI InChI=1S/C27H30FN7O/c1-4-36-27-30-17(2)24-26(32-27)35(25(31-24)20-9-21(28)12-29-11-20)14-19-7-5-18(6-8-19)13-34-16-22-10-23(34)15-33(22)3/h5-9,11-12,22-23H,4,10,13-16H2,1-3H3/t22-,23-/m0/s1
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n/an/a 10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450060
PNG
(9-{4-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]benzyl}-8-(...)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)[C@H]3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-3-5-18(6-4-17)22-15-32-9-7-19(22)8-10-32/h3-6,11-13,19,22H,7-10,14-15H2,1-2H3/t22-/m1/s1
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n/an/a 10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450046
PNG
(9-{[1-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-1H-pyraz...)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3cnn(CC4CN5CCC4CC5)c3)c2n1
Show InChI InChI=1S/C25H29FN8O/c1-3-35-25-29-16(2)22-24(31-25)34(23(30-22)19-8-21(26)11-27-10-19)13-17-9-28-33(12-17)15-20-14-32-6-4-18(20)5-7-32/h8-12,18,20H,3-7,13-15H2,1-2H3
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n/an/a 10n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450167
PNG
(US10703755, Example 364)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3cccc(c3)C3=CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H25FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-4-3-5-19(10-17)22-15-32-8-6-18(22)7-9-32/h3-5,10-13,15,18H,6-9,14H2,1-2H3
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n/an/a 11n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450174
PNG
(US10703755, Example 372)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3OC)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C28H31FN6O2/c1-4-37-28-31-17(2)25-27(33-28)35(26(32-25)21-11-22(29)14-30-13-21)15-20-6-5-19(12-24(20)36-3)23-16-34-9-7-18(23)8-10-34/h5-6,11-14,18,23H,4,7-10,15-16H2,1-3H3
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n/an/a 11n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450128
PNG
(US10703755, Example 311)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(c3)C#N)n(Cc3ccc(CN4CC5CC4CN5C)cc3F)c2n1
Show InChI InChI=1S/C28H29FN8O/c1-4-38-28-32-17(2)25-27(34-28)37(26(33-25)21-7-19(10-30)11-31-12-21)14-20-6-5-18(8-24(20)29)13-36-16-22-9-23(36)15-35(22)3/h5-8,11-12,22-23H,4,9,13-16H2,1-3H3
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n/an/a 11n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450059
PNG
(US10703755, Example 176)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)[C@H]3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C27H29FN6O/c1-3-35-27-30-17(2)24-26(32-27)34(25(31-24)21-12-22(28)14-29-13-21)15-18-4-6-19(7-5-18)23-16-33-10-8-20(23)9-11-33/h4-7,12-14,20,23H,3,8-11,15-16H2,1-2H3/t23-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450151
PNG
(US10703755, Example 344)
Show SMILES COc1nc(C)c2nc(-c3cccc(c3)C#N)n(Cc3ccc(cc3F)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C28H27FN6O/c1-17-25-27(33-28(31-17)36-2)35(26(32-25)21-5-3-4-18(12-21)14-30)15-22-7-6-20(13-24(22)29)23-16-34-10-8-19(23)9-11-34/h3-7,12-13,19,23H,8-11,15-16H2,1-2H3
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n/an/a 12n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450187
PNG
(US10703755, Example 386)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3cccc(c3)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-4-3-5-19(10-17)22-15-32-8-6-18(22)7-9-32/h3-5,10-13,18,22H,6-9,14-15H2,1-2H3
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n/an/a 13n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450192
PNG
(9-{4-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-2-fluorobe...)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)[C@@H]3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)19-9-20(27)12-29-11-19)13-18-4-3-17(10-22(18)28)21-14-33-7-5-16(21)6-8-33/h3-4,9-12,16,21H,5-8,13-14H2,1-2H3/t21-/m1/s1
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n/an/a 13n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450114
PNG
(US10703755, Example 295)
Show SMILES COc1nc(C)c2nc(-c3cncc(c3)C#N)n(Cc3ccc(OC4CC5CCC(C4)N5C)cc3F)c2n1
Show InChI InChI=1S/C28H28FN7O2/c1-16-25-27(34-28(32-16)37-3)36(26(33-25)19-8-17(12-30)13-31-14-19)15-18-4-7-22(11-24(18)29)38-23-9-20-5-6-21(10-23)35(20)2/h4,7-8,11,13-14,20-21,23H,5-6,9-10,15H2,1-3H3
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n/an/a 13n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450136
PNG
(US10703755, Example 322)
Show SMILES COc1nc(C)c2nc(-c3cncc(c3)C#N)n(Cc3ccc(OC4CN5CCC4CC5)cc3F)c2n1
Show InChI InChI=1S/C27H26FN7O2/c1-16-24-26(33-27(31-16)36-2)35(25(32-24)20-9-17(11-29)12-30-13-20)14-19-3-4-21(10-22(19)28)37-23-15-34-7-5-18(23)6-8-34/h3-4,9-10,12-13,18,23H,5-8,14-15H2,1-2H3
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n/an/a 13n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450016
PNG
(US10703755, Example 133)
Show SMILES CCCN1C[C@@H]2C[C@H]1CN2Cc1ccc(Cn2c(nc3c(C)nc(OC)nc23)-c2cncc(F)c2)cc1
Show InChI InChI=1S/C28H32FN7O/c1-4-9-34-16-24-11-23(34)17-35(24)14-19-5-7-20(8-6-19)15-36-26(21-10-22(29)13-30-12-21)32-25-18(2)31-28(37-3)33-27(25)36/h5-8,10,12-13,23-24H,4,9,11,14-17H2,1-3H3/t23-,24-/m0/s1
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n/an/a 13n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450229
PNG
(US10703755, Example 437)
Show SMILES COc1nc(C)c2nc(-c3cccnc3)n(Cc3ccc(O[C@@H]4C[C@@H]5CC[C@H](C4)N5)cc3F)c2n1
Show InChI InChI=1S/C26H27FN6O2/c1-15-23-25(32-26(29-15)34-2)33(24(31-23)16-4-3-9-28-13-16)14-17-5-8-20(12-22(17)27)35-21-10-18-6-7-19(11-21)30-18/h3-5,8-9,12-13,18-19,21,30H,6-7,10-11,14H2,1-2H3/t18-,19+,21+
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n/an/a 16n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450048
PNG
(9-[4-(1-Azabicyclo[2.2.2]oct-3-yl)benzyl]-8-(5-flu...)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H27FN6O/c1-16-23-25(31-26(29-16)34-2)33(24(30-23)20-11-21(27)13-28-12-20)14-17-3-5-18(6-4-17)22-15-32-9-7-19(22)8-10-32/h3-6,11-13,19,22H,7-10,14-15H2,1-2H3
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n/an/a 16n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450031
PNG
(1-[4-(4-{[6-Amino-2-ethoxy-8-(5-fluoropyridin-3-yl...)
Show SMILES CCOc1nc(N)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3)C3CCN(CC3)C(=O)CN(C)C)c2n1
Show InChI InChI=1S/C28H33FN8O2/c1-4-39-28-33-25(30)24-27(34-28)37(26(32-24)21-13-22(29)15-31-14-21)16-18-5-7-19(8-6-18)20-9-11-36(12-10-20)23(38)17-35(2)3/h5-8,13-15,20H,4,9-12,16-17H2,1-3H3,(H2,30,33,34)
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n/an/a 16n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450211
PNG
(US10703755, Example 415)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@@H]4CCN(C)C4)cc3F)c2n1
Show InChI InChI=1S/C24H24F2N6O2/c1-14-21-23(30-24(28-14)33-3)32(22(29-21)16-8-17(25)11-27-10-16)12-15-4-5-18(9-20(15)26)34-19-6-7-31(2)13-19/h4-5,8-11,19H,6-7,12-13H2,1-3H3/t19-/m1/s1
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n/an/a 16n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450210
PNG
(US10703755, Example 414)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(O[C@H]4CCN(C)C4)cc3F)c2n1
Show InChI InChI=1S/C24H24F2N6O2/c1-14-21-23(30-24(28-14)33-3)32(22(29-21)16-8-17(25)11-27-10-16)12-15-4-5-18(9-20(15)26)34-19-6-7-31(2)13-19/h4-5,8-11,19H,6-7,12-13H2,1-3H3/t19-/m0/s1
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n/an/a 16n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450110
PNG
(US10703755, Example 291)
Show SMILES CCN1CCC(C1)c1ccc(Cn2c(nc3c(C)nc(OC)nc23)-c2cncc(F)c2)c(F)c1
Show InChI InChI=1S/C25H26F2N6O/c1-4-32-8-7-17(13-32)16-5-6-18(21(27)10-16)14-33-23(19-9-20(26)12-28-11-19)30-22-15(2)29-25(34-3)31-24(22)33/h5-6,9-12,17H,4,7-8,13-14H2,1-3H3
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n/an/a 17n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450233
PNG
(US10703755, Example 443)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3cc(ccc3F)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H26F2N6O/c1-15-23-25(32-26(30-15)35-2)34(24(31-23)18-10-20(27)12-29-11-18)13-19-9-17(3-4-22(19)28)21-14-33-7-5-16(21)6-8-33/h3-4,9-12,16,21H,5-8,13-14H2,1-2H3
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n/an/a 17n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450112
PNG
(US10703755, Example 293)
Show SMILES CCN1CCC(CC1)c1ccc(Cn2c(nc3c(C)nc(OC)nc23)-c2cccnc2)c(F)c1
Show InChI InChI=1S/C26H29FN6O/c1-4-32-12-9-18(10-13-32)19-7-8-21(22(27)14-19)16-33-24(20-6-5-11-28-15-20)30-23-17(2)29-26(34-3)31-25(23)33/h5-8,11,14-15,18H,4,9-10,12-13,16H2,1-3H3
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n/an/a 18n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450162
PNG
(US10703755, Example 358)
Show SMILES Cc1nc(O)nc2n(Cc3ccc(C4=CN5CCC4CC5)c(F)c3)c(nc12)-c1cncc(F)c1
Show InChI InChI=1S/C25H22F2N6O/c1-14-22-24(31-25(34)29-14)33(23(30-22)17-9-18(26)11-28-10-17)12-15-2-3-19(21(27)8-15)20-13-32-6-4-16(20)5-7-32/h2-3,8-11,13,16H,4-7,12H2,1H3,(H,29,31,34)
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n/an/a 18n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450227
PNG
(US10703755, Example 435)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(cc3F)C3CCNC3)c2n1
Show InChI InChI=1S/C23H22F2N6O/c1-13-20-22(30-23(28-13)32-2)31(21(29-20)17-7-18(24)11-27-10-17)12-16-4-3-14(8-19(16)25)15-5-6-26-9-15/h3-4,7-8,10-11,15,26H,5-6,9,12H2,1-2H3
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n/an/a 18n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450080
PNG
(US10703755, Example 260)
Show SMILES COc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4CCC4)cc3F)c2n1
Show InChI InChI=1S/C23H22F2N6O/c1-14-20-22(29-23(27-14)32-2)31(21(28-20)17-9-18(24)11-26-10-17)13-16-5-4-15(8-19(16)25)12-30-6-3-7-30/h4-5,8-11H,3,6-7,12-13H2,1-2H3
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n/an/a 18n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450054
PNG
(US10703755, Example 171)
Show SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(nc3)C3CN4CCC3CC4)c2n1
Show InChI InChI=1S/C26H28FN7O/c1-3-35-26-30-16(2)23-25(32-26)34(24(31-23)19-10-20(27)13-28-12-19)14-17-4-5-22(29-11-17)21-15-33-8-6-18(21)7-9-33/h4-5,10-13,18,21H,3,6-9,14-15H2,1-2H3
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n/an/a 18n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Toll-like receptor 7


(Homo sapiens (Human))
BDBM450015
PNG
(US10703755, Example 132)
Show SMILES CCN1C[C@@H]2C[C@H]1CN2Cc1ccc(Cn2c(nc3c(C)nc(OC)nc23)-c2cncc(F)c2)cc1
Show InChI InChI=1S/C27H30FN7O/c1-4-33-15-23-10-22(33)16-34(23)13-18-5-7-19(8-6-18)14-35-25(20-9-21(28)12-29-11-20)31-24-17(2)30-27(36-3)32-26(24)35/h5-9,11-12,22-23H,4,10,13-16H2,1-3H3/t22-,23-/m0/s1
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n/an/a 19n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorterô HEK293 cell), which is human emb...


US Patent US10703755 (2020)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 351 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%