Found 5 Enz. Inhib. hit(s) with all data for entry = 9215 
Affinity DataIC50: 50nMAssay Description:JAK1 (IC50): Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) is purchased from Carna Biosciences. 10 ng of JAK1...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:JAK1 (KI): For the determination of Ki, different amounts of compound are mixed with the enzyme and the enzymatic reaction is followed as a function ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 78nMAssay Description:JAK2 (Kd): JAK2 (Invitrogen, PV4210) is used at a final concentration of 5 nM. The binding experiment is performed in 50 mM Hepes pH 7.5, 0.01% Brij-...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:JAK2 (IC50): Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) is purchased from Invitrogen. 0.025 mU of JAK2 is ...More data for this Ligand-Target Pair
Affinity DataKd: 376nMAssay Description:JAK3 (IC50): Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) is purchased from Invitrogen. 0.025 mU of JAK3 is ...More data for this Ligand-Target Pair
