Compile Data Set for Download or QSAR
maximum 50k data
Found 59 Enz. Inhib. hit(s) with all data for entry = 5974
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103345(US8546392, 69)
Affinity DataIC50:  7nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103342(US8546392, 64)
Affinity DataIC50:  10nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103338(US8546392, 59)
Affinity DataIC50:  14nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103338(US8546392, 59)
Affinity DataIC50:  20nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103336(US8546392, 57)
Affinity DataIC50:  20nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335815(CHEMBL1650658 | N-{3-[2-Hydroxy-6-(3-hydroxyphenyl...)
Affinity DataIC50:  23nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103346(US8546392, 70)
Affinity DataIC50:  30nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103346(US8546392, 70)
Affinity DataIC50:  30nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335820(6-(3-Hydroxyphenyl)-1-(pyridin-4-yl)-2-naphthol | ...)
Affinity DataIC50:  39nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103337(US8546392, 58)
Affinity DataIC50:  40nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103344(US8546392, 68)
Affinity DataIC50:  50nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103340(US8546392, 62)
Affinity DataIC50:  50nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103347(US8546392, 71)
Affinity DataIC50:  60nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103334(US8546392, 19)
Affinity DataIC50:  70nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103339(US8546392, 60)
Affinity DataIC50:  90nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103343(US8546392, 66)
Affinity DataIC50:  114nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103341(US8546392, 63)
Affinity DataIC50:  140nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103338(US8546392, 59)
Affinity DataIC50:  150nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103346(US8546392, 70)
Affinity DataIC50:  195nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103338(US8546392, 59)
Affinity DataIC50:  221nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335817(6-(3-hydroxyphenyl)-1-(6-methoxypyridin-3-yl)napht...)
Affinity DataIC50:  224nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 1A2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335817(6-(3-hydroxyphenyl)-1-(6-methoxypyridin-3-yl)napht...)
Affinity DataIC50:  259nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103342(US8546392, 64)
Affinity DataIC50:  403nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103340(US8546392, 62)
Affinity DataIC50:  458nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335817(6-(3-hydroxyphenyl)-1-(6-methoxypyridin-3-yl)napht...)
Affinity DataIC50:  500nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103335(US8546392, 42)
Affinity DataIC50:  500nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103337(US8546392, 58)
Affinity DataIC50:  527nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335815(CHEMBL1650658 | N-{3-[2-Hydroxy-6-(3-hydroxyphenyl...)
Affinity DataIC50:  540nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335820(6-(3-Hydroxyphenyl)-1-(pyridin-4-yl)-2-naphthol | ...)
Affinity DataIC50:  583nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103345(US8546392, 69)
Affinity DataIC50:  601nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335815(CHEMBL1650658 | N-{3-[2-Hydroxy-6-(3-hydroxyphenyl...)
Affinity DataIC50:  680nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335817(6-(3-hydroxyphenyl)-1-(6-methoxypyridin-3-yl)napht...)
Affinity DataIC50:  840nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103338(US8546392, 59)
Affinity DataIC50:  880nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103336(US8546392, 57)
Affinity DataIC50:  959nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103334(US8546392, 19)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335815(CHEMBL1650658 | N-{3-[2-Hydroxy-6-(3-hydroxyphenyl...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103338(US8546392, 59)
Affinity DataIC50:  1.16E+3nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335817(6-(3-hydroxyphenyl)-1-(6-methoxypyridin-3-yl)napht...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335815(CHEMBL1650658 | N-{3-[2-Hydroxy-6-(3-hydroxyphenyl...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103334(US8546392, 19)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103344(US8546392, 68)
Affinity DataIC50:  1.76E+3nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM50335817(6-(3-hydroxyphenyl)-1-(6-methoxypyridin-3-yl)napht...)
Affinity DataIC50:  2.05E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103346(US8546392, 70)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103339(US8546392, 60)
Affinity DataIC50:  2.94E+3nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103334(US8546392, 19)
Affinity DataIC50:  3.99E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103335(US8546392, 42)
Affinity DataIC50:  4.19E+3nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103338(US8546392, 59)
Affinity DataIC50:  5.34E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103334(US8546392, 19)
Affinity DataIC50:  5.64E+3nMAssay Description:The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103334(US8546392, 19)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Universitaet Des Saarlandes

US Patent
LigandPNGBDBM103346(US8546392, 70)
Affinity DataIC50:  8.83E+3nMAssay Description:Inhibition assay using P450 CYP enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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