Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 6280
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120265(US8703947, 11a | US8703947, 11b)
Affinity DataKi: <1.00E+3nM ΔG°: <-35.6kJ/mole IC50: <1.00E+4nMpH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120270(US8703947, GRL- 0669AL)
Affinity DataKi: <1.00E+3nM ΔG°: <-35.6kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120275(US8703947, GRL- 1069AL)
Affinity DataKi: <1.00E+3nM ΔG°: <-35.6kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120273(US8703947, GRL- 0889AL)
Affinity DataKi: <1.00E+3nM ΔG°: <-35.6kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120268(US8703947, GRL- 0299)
Affinity DataKi: <1.00E+3nM ΔG°: <-35.6kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120276(US8703947, GRL- 1079AL)
Affinity DataKi: <1.00E+3nM ΔG°: <-35.6kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120271(US8703947, GRL- 0819AL)
Affinity DataKi: <1.00E+3nM ΔG°: <-35.6kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120272(US8703947, GRL- 0849AL)
Affinity DataKi: <1.00E+3nM ΔG°: <-35.6kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120267(US8703947, Comparison compound B)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120265(US8703947, 11a | US8703947, 11b)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM120264(US8703947, 10)
Affinity DataKi: <1.00E+4nM ΔG°: <-29.7kJ/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In DepthDetails US Patent