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Found 11 Enz. Inhib. hit(s) with all data for entry = 7657
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209011(Piperidine-1-sulfonic acid (3-methyl-benzo[b]thiop...)
Affinity DataIC50:  3.60nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209017(1-[(3-Methyl-benzo[b]thiophen-2-yl)-(4-trifluorome...)
Affinity DataIC50:  4.60nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209012(Morpholine-1-sulfonic acid (3-methyl-benzo[b]thiop...)
Affinity DataIC50:  5.70nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209021(N-(3-Bromo-benzo[b]thiophen-2-yl)-N-(4-fluoro-3-tr...)
Affinity DataIC50:  8.5nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209022(4-(2,2,2-Trifluoro-ethyl)-piperazine-1-sulfonic ac...)
Affinity DataIC50:  13nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209020(N-(3-Bromo-benzo[b]thiophen-2-yl)-N-(4-fluoro-3-tr...)
Affinity DataIC50:  18nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209015(4-Methyl-piperazine-1-sulfonic acid (3-methyl-benz...)
Affinity DataIC50:  46nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209013(4-Isopropyl-piperazine-1-sulfonic acid (3-methyl-b...)
Affinity DataIC50:  60nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209018(1-[(3-Methyl-benzo[b]thiophen-2-yl)-(4-trifluorome...)
Affinity DataIC50:  61nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209019(N-(4-Fluoro-3-trifluoromethyl-benzyl)-N-(3-methyl-...)
Affinity DataIC50:  62nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM209014(4-(3-Methyl-butyl)-piperazine-1-sulfonic acid (3-m...)
Affinity DataIC50:  71nMT: 2°CAssay Description:The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent