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Patent code US9278925

Compile Data Set for Download or QSAR
Found 146 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
PDB

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n/an/a 44n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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n/an/a 55n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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n/an/a 55n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220134
PNG
(US9278925, V.2-b)
Show SMILES Cc1ccc(cc1C1=C(O)[C@]2(CC[C@@H](CC2)C(F)(F)F)NC1=O)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C23H20ClF4NO2/c1-12-2-3-13(14-4-5-17(24)18(25)11-14)10-16(12)19-20(30)22(29-21(19)31)8-6-15(7-9-22)23(26,27)28/h2-5,10-11,15,30H,6-9H2,1H3,(H,29,31)/t15-,22+
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n/an/a 59n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 63n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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n/an/a 63n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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n/an/a 67n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220134
PNG
(US9278925, V.2-b)
Show SMILES Cc1ccc(cc1C1=C(O)[C@]2(CC[C@@H](CC2)C(F)(F)F)NC1=O)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C23H20ClF4NO2/c1-12-2-3-13(14-4-5-17(24)18(25)11-14)10-16(12)19-20(30)22(29-21(19)31)8-6-15(7-9-22)23(26,27)28/h2-5,10-11,15,30H,6-9H2,1H3,(H,29,31)/t15-,22+
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n/an/a 67n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 67n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
PDB

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n/an/a 67n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
PDB

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n/an/a 69n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220139
PNG
(US9278925, V.4-b)
Show SMILES COC[C@H]1CC[C@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-3-4-16(17-5-6-19(25)20(26)12-17)11-18(14)21-22(28)24(27-23(21)29)9-7-15(8-10-24)13-30-2/h3-6,11-12,15,28H,7-10,13H2,1-2H3,(H,27,29)/t15-,24+
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
PDB

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n/an/a 78n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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n/an/a 83n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
PDB

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n/an/a 84n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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n/an/a 87n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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n/an/a 87n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220137
PNG
(US9278925, V.3-b)
Show SMILES COC[C@H]1CC[C@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-3-4-18(17-5-7-19(25)8-6-17)13-20(15)21-22(27)24(26-23(21)28)11-9-16(10-12-24)14-29-2/h3-8,13,16,27H,9-12,14H2,1-2H3,(H,26,28)/t16-,24+
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220141
PNG
(US9278925, 1-2)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)C(F)(F)F
Show InChI InChI=1S/C24H22ClF4NO3/c1-13-3-4-14(15-5-6-17(25)18(26)12-15)11-16(13)19-20(31)22(30-21(19)32)7-9-23(33-2,10-8-22)24(27,28)29/h3-6,11-12,31H,7-10H2,1-2H3,(H,30,32)/t22-,23-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220141
PNG
(US9278925, 1-2)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)C(F)(F)F
Show InChI InChI=1S/C24H22ClF4NO3/c1-13-3-4-14(15-5-6-17(25)18(26)12-15)11-16(13)19-20(31)22(30-21(19)32)7-9-23(33-2,10-8-22)24(27,28)29/h3-6,11-12,31H,7-10H2,1-2H3,(H,30,32)/t22-,23-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220131
PNG
(US9278925, V.1-b)
Show SMILES Cc1ccc(cc1C1=C(O)[C@]2(CC[C@@H](CC2)C(F)(F)F)NC1=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H21ClF3NO2/c1-13-2-3-15(14-4-6-17(24)7-5-14)12-18(13)19-20(29)22(28-21(19)30)10-8-16(9-11-22)23(25,26)27/h2-7,12,16,29H,8-11H2,1H3,(H,28,30)/t16-,22+
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220131
PNG
(US9278925, V.1-b)
Show SMILES Cc1ccc(cc1C1=C(O)[C@]2(CC[C@@H](CC2)C(F)(F)F)NC1=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H21ClF3NO2/c1-13-2-3-15(14-4-6-17(24)7-5-14)12-18(13)19-20(29)22(28-21(19)30)10-8-16(9-11-22)23(25,26)27/h2-7,12,16,29H,8-11H2,1H3,(H,28,30)/t16-,22+
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220141
PNG
(US9278925, 1-2)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)C(F)(F)F
Show InChI InChI=1S/C24H22ClF4NO3/c1-13-3-4-14(15-5-6-17(25)18(26)12-15)11-16(13)19-20(31)22(30-21(19)32)7-9-23(33-2,10-8-22)24(27,28)29/h3-6,11-12,31H,7-10H2,1-2H3,(H,30,32)/t22-,23-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
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n/an/a 131n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220142
PNG
(US9278925, 1-3)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)OC
Show InChI InChI=1S/C25H28ClNO4/c1-16-4-5-18(17-6-8-19(26)9-7-17)14-20(16)21-22(28)25(27-23(21)29)12-10-24(31-3,11-13-25)15-30-2/h4-9,14,28H,10-13,15H2,1-3H3,(H,27,29)/t24-,25-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220142
PNG
(US9278925, 1-3)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)OC
Show InChI InChI=1S/C25H28ClNO4/c1-16-4-5-18(17-6-8-19(26)9-7-17)14-20(16)21-22(28)25(27-23(21)29)12-10-24(31-3,11-13-25)15-30-2/h4-9,14,28H,10-13,15H2,1-3H3,(H,27,29)/t24-,25-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
PDB

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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 184n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 1


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220134
PNG
(US9278925, V.2-b)
Show SMILES Cc1ccc(cc1C1=C(O)[C@]2(CC[C@@H](CC2)C(F)(F)F)NC1=O)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C23H20ClF4NO2/c1-12-2-3-13(14-4-5-17(24)18(25)11-14)10-16(12)19-20(30)22(29-21(19)31)8-6-15(7-9-22)23(26,27)28/h2-5,10-11,15,30H,6-9H2,1H3,(H,29,31)/t15-,22+
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220137
PNG
(US9278925, V.3-b)
Show SMILES COC[C@H]1CC[C@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-3-4-18(17-5-7-19(25)8-6-17)13-20(15)21-22(27)24(26-23(21)28)11-9-16(10-12-24)14-29-2/h3-8,13,16,27H,9-12,14H2,1-2H3,(H,26,28)/t16-,24+
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220134
PNG
(US9278925, V.2-b)
Show SMILES Cc1ccc(cc1C1=C(O)[C@]2(CC[C@@H](CC2)C(F)(F)F)NC1=O)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C23H20ClF4NO2/c1-12-2-3-13(14-4-5-17(24)18(25)11-14)10-16(12)19-20(30)22(29-21(19)31)8-6-15(7-9-22)23(26,27)28/h2-5,10-11,15,30H,6-9H2,1H3,(H,29,31)/t15-,22+
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220131
PNG
(US9278925, V.1-b)
Show SMILES Cc1ccc(cc1C1=C(O)[C@]2(CC[C@@H](CC2)C(F)(F)F)NC1=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H21ClF3NO2/c1-13-2-3-15(14-4-6-17(24)7-5-14)12-18(13)19-20(29)22(28-21(19)30)10-8-16(9-11-22)23(25,26)27/h2-7,12,16,29H,8-11H2,1H3,(H,28,30)/t16-,22+
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220139
PNG
(US9278925, V.4-b)
Show SMILES COC[C@H]1CC[C@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-3-4-16(17-5-6-19(25)20(26)12-17)11-18(14)21-22(28)24(27-23(21)29)9-7-15(8-10-24)13-30-2/h3-6,11-12,15,28H,7-10,13H2,1-2H3,(H,27,29)/t15-,24+
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220131
PNG
(US9278925, V.1-b)
Show SMILES Cc1ccc(cc1C1=C(O)[C@]2(CC[C@@H](CC2)C(F)(F)F)NC1=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H21ClF3NO2/c1-13-2-3-15(14-4-6-17(24)7-5-14)12-18(13)19-20(29)22(28-21(19)30)10-8-16(9-11-22)23(25,26)27/h2-7,12,16,29H,8-11H2,1H3,(H,28,30)/t16-,22+
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220141
PNG
(US9278925, 1-2)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)C(F)(F)F
Show InChI InChI=1S/C24H22ClF4NO3/c1-13-3-4-14(15-5-6-17(25)18(26)12-15)11-16(13)19-20(31)22(30-21(19)32)7-9-23(33-2,10-8-22)24(27,28)29/h3-6,11-12,31H,7-10H2,1-2H3,(H,30,32)/t22-,23-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220141
PNG
(US9278925, 1-2)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)C(F)(F)F
Show InChI InChI=1S/C24H22ClF4NO3/c1-13-3-4-14(15-5-6-17(25)18(26)12-15)11-16(13)19-20(31)22(30-21(19)32)7-9-23(33-2,10-8-22)24(27,28)29/h3-6,11-12,31H,7-10H2,1-2H3,(H,30,32)/t22-,23-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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BAYER INTELLECTUAL PROPERTY GMBH

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Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 2.14E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.33E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.33E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.51E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.51E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.53E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.53E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.75E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.75E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220141
PNG
(US9278925, 1-2)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)C(F)(F)F
Show InChI InChI=1S/C24H22ClF4NO3/c1-13-3-4-14(15-5-6-17(25)18(26)12-15)11-16(13)19-20(31)22(30-21(19)32)7-9-23(33-2,10-8-22)24(27,28)29/h3-6,11-12,31H,7-10H2,1-2H3,(H,30,32)/t22-,23-
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n/an/a 2.76E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.86E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 2.86E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 2.90E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 2.90E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
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n/an/a 3.05E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 3.13E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 3.13E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
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n/an/a 3.30E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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n/an/a 3.31E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 3.32E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 3.32E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 3.36E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 3.36E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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n/an/a 3.39E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
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n/an/a 3.82E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 3.93E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 3.93E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 3.99E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 3.99E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
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n/an/a 4.06E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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n/an/a 4.15E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220143
PNG
(US9278925, 1-4)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1)OC
Show InChI InChI=1S/C25H27ClFNO4/c1-15-4-5-16(17-6-7-19(26)20(27)13-17)12-18(15)21-22(29)25(28-23(21)30)10-8-24(32-3,9-11-25)14-31-2/h4-7,12-13,29H,8-11,14H2,1-3H3,(H,28,30)/t24-,25-
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n/an/a 4.35E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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n/an/a 4.50E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 4.54E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 4.54E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 4.99E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 4.99E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 5.14E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 5.14E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 5.20E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220130
PNG
(US9278925, V.1-a | US9278925, V.3-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClNO3/c1-15-4-5-17(16-6-8-18(25)9-7-16)14-19(15)20-21(27)24(26-22(20)28)12-10-23(2,29-3)11-13-24/h4-9,14,27H,10-13H2,1-3H3,(H,26,28)/t23-,24-
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n/an/a 5.20E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 5.80E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 5.80E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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n/an/a 6.46E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220142
PNG
(US9278925, 1-3)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)OC
Show InChI InChI=1S/C25H28ClNO4/c1-16-4-5-18(17-6-8-19(26)9-7-17)14-20(16)21-22(28)25(27-23(21)29)12-10-24(31-3,11-13-25)15-30-2/h4-9,14,28H,10-13,15H2,1-3H3,(H,27,29)/t24-,25-
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n/an/a 6.55E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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n/an/a 7.42E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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US Patent
n/an/a 7.81E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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US Patent
n/an/a 7.81E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220142
PNG
(US9278925, 1-3)
Show SMILES COC[C@@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)OC
Show InChI InChI=1S/C25H28ClNO4/c1-16-4-5-18(17-6-8-19(26)9-7-17)14-20(16)21-22(28)25(27-23(21)29)12-10-24(31-3,11-13-25)15-30-2/h4-9,14,28H,10-13,15H2,1-3H3,(H,27,29)/t24-,25-
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n/an/a 8.08E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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US Patent
n/an/a 8.63E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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US Patent
n/an/a 8.63E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 8.81E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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US Patent
n/an/a 8.81E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 9.20E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 9.20E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 9.56E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220133
PNG
(US9278925, V.2-a | US9278925, V.4-a)
Show SMILES CO[C@@]1(C)CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C24H25ClFNO3/c1-14-4-5-15(16-6-7-18(25)19(26)13-16)12-17(14)20-21(28)24(27-22(20)29)10-8-23(2,30-3)9-11-24/h4-7,12-13,28H,8-11H2,1-3H3,(H,27,29)/t23-,24-
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n/an/a 9.56E+3n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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n/an/a 1.15E+4n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
Acetyl-CoA carboxylase 2


(Homo sapiens (Human))
BDBM220140
PNG
(US9278925, 1-1)
Show SMILES CO[C@]1(CC[C@@]2(CC1)NC(=O)C(=C2O)c1cc(ccc1C)-c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C24H23ClF3NO3/c1-14-3-4-16(15-5-7-17(25)8-6-15)13-18(14)19-20(30)22(29-21(19)31)9-11-23(32-2,12-10-22)24(26,27)28/h3-8,13,30H,9-12H2,1-2H3,(H,29,31)/t22-,23-
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n/an/a 1.35E+4n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%