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Patent code US9315492

Compile Data Set for Download or QSAR
Found 29 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221928
PNG
(US9315492, 29)
Show SMILES CC(C)Oc1ccc(cc1C)C1=NC(N=N1)c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C23H28N4O2/c1-14(2)29-20-7-6-17(10-15(20)3)21-25-22(27-26-21)18-5-4-16-8-9-23(24,13-28)12-19(16)11-18/h4-7,10-11,14,22,28H,8-9,12-13,24H2,1-3H3
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n/an/a 0.400n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221914
PNG
(US9315492, 11)
Show SMILES CC(C)Oc1ccc(cc1C(F)(F)F)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C23H24F3N3O3/c1-13(2)31-19-6-5-16(10-18(19)23(24,25)26)21-29-28-20(32-21)15-4-3-14-7-8-22(27,12-30)11-17(14)9-15/h3-6,9-10,13,30H,7-8,11-12,27H2,1-2H3
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n/an/a 0.400n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221926
PNG
(US9315492, 27)
Show SMILES CC(C)Oc1ccc(cc1C)-c1noc(n1)-c1ccc2CC(N)(CO)CCc2c1
Show InChI InChI=1S/C23H27N3O3/c1-14(2)28-20-7-6-17(10-15(20)3)21-25-22(29-26-21)18-4-5-19-12-23(24,13-27)9-8-16(19)11-18/h4-7,10-11,14,27H,8-9,12-13,24H2,1-3H3
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n/an/a 1.20n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221932
PNG
(US9315492, 22)
Show SMILES CC(C)Oc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C23H27N3O3/c1-14(2)28-20-7-6-17(10-15(20)3)21-25-26-22(29-21)18-5-4-16-8-9-23(24,13-27)12-19(16)11-18/h4-7,10-11,14,27H,8-9,12-13,24H2,1-3H3
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n/an/a 3n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221929
PNG
(US9315492, 31 | US9315492, 32)
Show SMILES CC(C)Oc1ccc(cc1C)-c1cn(nn1)-c1ccc2CC(N)(CO)CCc2c1
Show InChI InChI=1S/C23H28N4O2/c1-15(2)29-22-7-5-18(10-16(22)3)21-13-27(26-25-21)20-6-4-19-12-23(24,14-28)9-8-17(19)11-20/h4-7,10-11,13,15,28H,8-9,12,14,24H2,1-3H3
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n/an/a 5n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221918
PNG
(US9315492, 17)
Show SMILES COCCOc1ccc(cc1C(F)(F)F)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C23H24F3N3O4/c1-31-8-9-32-19-5-4-16(11-18(19)23(24,25)26)21-29-28-20(33-21)15-3-2-14-6-7-22(27,13-30)12-17(14)10-15/h2-5,10-11,30H,6-9,12-13,27H2,1H3
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n/an/a 10.2n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221916
PNG
(US9315492, 15)
Show SMILES COc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C21H23N3O3/c1-13-9-15(5-6-18(13)26-2)19-23-24-20(27-19)16-4-3-14-7-8-21(22,12-25)11-17(14)10-16/h3-6,9-10,25H,7-8,11-12,22H2,1-2H3
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n/an/a 16n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221913
PNG
(US9315492, 10)
Show SMILES COCCOc1ccc(cc1)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C22H25N3O4/c1-27-10-11-28-19-6-4-16(5-7-19)20-24-25-21(29-20)17-3-2-15-8-9-22(23,14-26)13-18(15)12-17/h2-7,12,26H,8-11,13-14,23H2,1H3
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n/an/a 31.7n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221922
PNG
(US9315492, 23)
Show SMILES CCNC1(CO)CCc2ccc(cc2C1)-c1nnc(o1)-c1ccc(OC(C)C)c(C)c1
Show InChI InChI=1S/C25H31N3O3/c1-5-26-25(15-29)11-10-18-6-7-20(13-21(18)14-25)24-28-27-23(31-24)19-8-9-22(17(4)12-19)30-16(2)3/h6-9,12-13,16,26,29H,5,10-11,14-15H2,1-4H3
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n/an/a 37.6n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221919
PNG
(US9315492, 18)
Show SMILES COCCOc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C23H27N3O4/c1-15-11-17(5-6-20(15)29-10-9-28-2)21-25-26-22(30-21)18-4-3-16-7-8-23(24,14-27)13-19(16)12-18/h3-6,11-12,27H,7-10,13-14,24H2,1-2H3
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n/an/a 41.1n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221924
PNG
(US9315492, 25)
Show SMILES CC(C)Oc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(CO)(Cc2c1)NC(C)=O
Show InChI InChI=1S/C25H29N3O4/c1-15(2)31-22-8-7-19(11-16(22)3)23-27-28-24(32-23)20-6-5-18-9-10-25(14-29,26-17(4)30)13-21(18)12-20/h5-8,11-12,15,29H,9-10,13-14H2,1-4H3,(H,26,30)
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n/an/a 45.5n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221917
PNG
(US9315492, 16)
Show SMILES CC(C)Oc1ccc(cc1)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C22H25N3O3/c1-14(2)27-19-7-5-16(6-8-19)20-24-25-21(28-20)17-4-3-15-9-10-22(23,13-26)12-18(15)11-17/h3-8,11,14,26H,9-10,12-13,23H2,1-2H3
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n/an/a 46n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221923
PNG
(US9315492, 24)
Show SMILES CC(C)Oc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(CO)(Cc2c1)N(C)C
Show InChI InChI=1S/C25H31N3O3/c1-16(2)30-22-9-8-19(12-17(22)3)23-26-27-24(31-23)20-7-6-18-10-11-25(15-29,28(4)5)14-21(18)13-20/h6-9,12-13,16,29H,10-11,14-15H2,1-5H3
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n/an/a 46n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221920
PNG
(US9315492, 19)
Show SMILES CC(C)Oc1ccc(cn1)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C21H24N4O3/c1-13(2)27-18-6-5-16(11-23-18)20-25-24-19(28-20)15-4-3-14-7-8-21(22,12-26)10-17(14)9-15/h3-6,9,11,13,26H,7-8,10,12,22H2,1-2H3
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n/an/a 61.2n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221925
PNG
(US9315492, 26)
Show SMILES CC(C)Oc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(CO)(Cc2c1)NS(C)(=O)=O
Show InChI InChI=1S/C24H29N3O5S/c1-15(2)31-21-8-7-18(11-16(21)3)22-25-26-23(32-22)19-6-5-17-9-10-24(14-28,13-20(17)12-19)27-33(4,29)30/h5-8,11-12,15,27-28H,9-10,13-14H2,1-4H3
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n/an/a 86n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221929
PNG
(US9315492, 31 | US9315492, 32)
Show SMILES CC(C)Oc1ccc(cc1C)-c1cn(nn1)-c1ccc2CC(N)(CO)CCc2c1
Show InChI InChI=1S/C23H28N4O2/c1-15(2)29-22-7-5-18(10-16(22)3)21-13-27(26-25-21)20-6-4-19-12-23(24,14-28)9-8-17(19)11-20/h4-7,10-11,13,15,28H,8-9,12,14,24H2,1-3H3
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n/an/a 125n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221921
PNG
(US9315492, 20)
Show SMILES CCOc1ccc(cc1OCC)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C23H27N3O4/c1-3-28-19-8-7-17(12-20(19)29-4-2)22-26-25-21(30-22)16-6-5-15-9-10-23(24,14-27)13-18(15)11-16/h5-8,11-12,27H,3-4,9-10,13-14,24H2,1-2H3
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n/an/a 179n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221931
PNG
(US9315492, 21)
Show SMILES CC(C)Oc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(CO)(Cc2c1)NCc1ccccc1
Show InChI InChI=1S/C30H33N3O3/c1-20(2)35-27-12-11-24(15-21(27)3)28-32-33-29(36-28)25-10-9-23-13-14-30(19-34,17-26(23)16-25)31-18-22-7-5-4-6-8-22/h4-12,15-16,20,31,34H,13-14,17-19H2,1-3H3
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n/an/a 179n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221927
PNG
(US9315492, 28 | US9315492, 30)
Show SMILES CC(C)Oc1ccc(cc1C)-c1nc(no1)-c1ccc2CC(N)(CO)CCc2c1
Show InChI InChI=1S/C23H27N3O3/c1-14(2)28-20-7-6-18(10-15(20)3)22-25-21(26-29-22)17-4-5-19-12-23(24,13-27)9-8-16(19)11-17/h4-7,10-11,14,27H,8-9,12-13,24H2,1-3H3
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n/an/a 473n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221915
PNG
(US9315492, 12)
Show SMILES NC1(CO)CCc2cc(ccc2C1)-c1nc(no1)-c1ccnc(c1)[N+]([O-])=O
Show InChI InChI=1S/C18H17N5O4/c19-18(10-24)5-3-11-7-13(1-2-14(11)9-18)17-21-16(22-27-17)12-4-6-20-15(8-12)23(25)26/h1-2,4,6-8,24H,3,5,9-10,19H2
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n/an/a 620n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM221927
PNG
(US9315492, 28 | US9315492, 30)
Show SMILES CC(C)Oc1ccc(cc1C)-c1nc(no1)-c1ccc2CC(N)(CO)CCc2c1
Show InChI InChI=1S/C23H27N3O3/c1-14(2)28-20-7-6-18(10-15(20)3)22-25-21(26-29-22)17-4-5-19-12-23(24,13-27)9-8-16(19)11-17/h4-7,10-11,14,27H,8-9,12-13,24H2,1-3H3
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n/an/a 749n/an/an/an/a7.4n/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4). The test compound was prepared as 4 of ...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM221926
PNG
(US9315492, 27)
Show SMILES CC(C)Oc1ccc(cc1C)-c1noc(n1)-c1ccc2CC(N)(CO)CCc2c1
Show InChI InChI=1S/C23H27N3O3/c1-14(2)28-20-7-6-17(10-15(20)3)21-25-22(29-26-21)18-4-5-19-12-23(24,13-27)9-8-16(19)11-18/h4-7,10-11,14,27H,8-9,12-13,24H2,1-3H3
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n/an/an/an/a 20n/an/an/an/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Assay procedures: OCC culture solution was preheated in water tank at 37 C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM221913
PNG
(US9315492, 10)
Show SMILES COCCOc1ccc(cc1)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C22H25N3O4/c1-27-10-11-28-19-6-4-16(5-7-19)20-24-25-21(29-20)17-3-2-15-8-9-22(23,14-26)13-18(15)12-17/h2-7,12,26H,8-11,13-14,23H2,1H3
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n/an/an/an/a 77n/an/an/an/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Assay procedures: OCC culture solution was preheated in water tank at 37 C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM221914
PNG
(US9315492, 11)
Show SMILES CC(C)Oc1ccc(cc1C(F)(F)F)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C23H24F3N3O3/c1-13(2)31-19-6-5-16(10-18(19)23(24,25)26)21-29-28-20(32-21)15-4-3-14-7-8-22(27,12-30)11-17(14)9-15/h3-6,9-10,13,30H,7-8,11-12,27H2,1-2H3
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n/an/an/an/a 3.10n/an/an/an/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Assay procedures: OCC culture solution was preheated in water tank at 37 C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM221928
PNG
(US9315492, 29)
Show SMILES CC(C)Oc1ccc(cc1C)C1=NC(N=N1)c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C23H28N4O2/c1-14(2)29-20-7-6-17(10-15(20)3)21-25-22(27-26-21)18-5-4-16-8-9-23(24,13-28)12-19(16)11-18/h4-7,10-11,14,22,28H,8-9,12-13,24H2,1-3H3
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n/an/an/an/a 9.90n/an/an/an/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Assay procedures: OCC culture solution was preheated in water tank at 37 C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM221923
PNG
(US9315492, 24)
Show SMILES CC(C)Oc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(CO)(Cc2c1)N(C)C
Show InChI InChI=1S/C25H31N3O3/c1-16(2)30-22-9-8-19(12-17(22)3)23-26-27-24(31-23)20-7-6-18-10-11-25(15-29,28(4)5)14-21(18)13-20/h6-9,12-13,16,29H,10-11,14-15H2,1-5H3
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n/an/an/an/a 354n/an/an/an/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Assay procedures: OCC culture solution was preheated in water tank at 37 C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM221916
PNG
(US9315492, 15)
Show SMILES COc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C21H23N3O3/c1-13-9-15(5-6-18(13)26-2)19-23-24-20(27-19)16-4-3-14-7-8-21(22,12-25)11-17(14)10-16/h3-6,9-10,25H,7-8,11-12,22H2,1-2H3
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n/an/an/an/a 27n/an/an/an/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Assay procedures: OCC culture solution was preheated in water tank at 37 C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM221932
PNG
(US9315492, 22)
Show SMILES CC(C)Oc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1
Show InChI InChI=1S/C23H27N3O3/c1-14(2)28-20-7-6-17(10-15(20)3)21-25-26-22(29-21)18-5-4-16-8-9-23(24,13-27)12-19(16)11-18/h4-7,10-11,14,27H,8-9,12-13,24H2,1-3H3
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n/an/an/an/a 8n/an/an/an/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Assay procedures: OCC culture solution was preheated in water tank at 37 C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...


Citation and Details
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM221929
PNG
(US9315492, 31 | US9315492, 32)
Show SMILES CC(C)Oc1ccc(cc1C)-c1cn(nn1)-c1ccc2CC(N)(CO)CCc2c1
Show InChI InChI=1S/C23H28N4O2/c1-15(2)29-22-7-5-18(10-16(22)3)21-13-27(26-25-21)20-6-4-19-12-23(24,14-28)9-8-17(19)11-20/h4-7,10-11,13,15,28H,8-9,12,14,24H2,1-3H3
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n/an/an/an/a 14.3n/an/an/an/a



Beijing Foreland Biopharma Co., Ltd.

US Patent


Assay Description
Assay procedures: OCC culture solution was preheated in water tank at 37 C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%