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Patent code US9328096

Compile Data Set for Download or QSAR

Found 800 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226864
PNG
(US9328096, 557)
Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)ccn1
Show InChI InChI=1S/C28H20Cl2FN7O2/c29-20-13-21(30)19(12-18(20)26-22(31)7-4-9-34-26)27(39)36-25-14-23(37-38(25)17-5-2-1-3-6-17)28(40)35-15-16-8-10-33-24(32)11-16/h1-14H,15H2,(H2,32,33)(H,35,40)(H,36,39)
PDB

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UniChem
US Patent
n/an/a 1.02n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM227148
PNG
(US9328096, 836)
Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)ccn1
Show InChI InChI=1S/C28H20ClF2N7O2/c29-20-13-22(31)19(26-21(30)7-4-9-34-26)12-18(20)27(39)36-25-14-23(37-38(25)17-5-2-1-3-6-17)28(40)35-15-16-8-10-33-24(32)11-16/h1-14H,15H2,(H2,32,33)(H,35,40)(H,36,39)
PDB

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UniChem
US Patent
n/an/a 1.04n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226929
PNG
(US9328096, 617)
Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)ccn1
Show InChI InChI=1S/C28H21Cl2N7O2/c29-21-14-22(30)20(13-19(21)23-8-4-5-10-32-23)27(38)35-26-15-24(36-37(26)18-6-2-1-3-7-18)28(39)34-16-17-9-11-33-25(31)12-17/h1-15H,16H2,(H2,31,33)(H,34,39)(H,35,38)
PDB

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PC sid
UniChem
US Patent
n/an/a 1.17n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226759
PNG
(US9328096, 452)
Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ccc(F)cn3)n(n2)-c2ccccc2)ccn1
Show InChI InChI=1S/C28H20Cl2FN7O2/c29-21-12-22(30)20(11-19(21)23-7-6-17(31)15-34-23)27(39)36-26-13-24(37-38(26)18-4-2-1-3-5-18)28(40)35-14-16-8-9-33-25(32)10-16/h1-13,15H,14H2,(H2,32,33)(H,35,40)(H,36,39)
PDB

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US Patent
n/an/a 1.43n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226847
PNG
(US9328096, 540)
Show SMILES Cc1n[nH]cc1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H18Cl2FN7O2/c1-14-22(13-31-34-14)32-26(38)21-12-23(36(35-21)15-6-3-2-4-7-15)33-25(37)17-10-16(18(27)11-19(17)28)24-20(29)8-5-9-30-24/h2-13H,1H3,(H,31,34)(H,32,38)(H,33,37)
PDB

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PC sid
UniChem
US Patent
n/an/a 1.51n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226527
PNG
(US9328096, 220)
Show SMILES Cc1n[nH]c(C)c1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ccccn2)n(n1)-c1ccccc1
Show InChI InChI=1S/C27H21Cl2N7O2/c1-15-25(16(2)34-33-15)32-27(38)23-14-24(36(35-23)17-8-4-3-5-9-17)31-26(37)19-12-18(20(28)13-21(19)29)22-10-6-7-11-30-22/h3-14H,1-2H3,(H,31,37)(H,32,38)(H,33,34)
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PC sid
UniChem
US Patent
n/an/a 1.71n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226611
PNG
(US9328096, 304)
Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)ccn1
Show InChI InChI=1S/C28H21ClFN7O2/c29-21-14-22(30)20(23-8-4-5-10-32-23)13-19(21)27(38)35-26-15-24(36-37(26)18-6-2-1-3-7-18)28(39)34-16-17-9-11-33-25(31)12-17/h1-15H,16H2,(H2,31,33)(H,34,39)(H,35,38)
PDB

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PC sid
UniChem
US Patent
n/an/a 1.71n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226486
PNG
(US9328096, 179)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cn[nH]c2)c(Cl)cc1Cl
Show InChI InChI=1S/C26H18Cl2FN7O2/c27-19-10-20(28)18(9-17(19)24-21(29)7-4-8-30-24)25(37)34-23-11-22(26(38)31-12-15-13-32-33-14-15)35-36(23)16-5-2-1-3-6-16/h1-11,13-14H,12H2,(H,31,38)(H,32,33)(H,34,37)
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PC sid
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US Patent
n/an/a 1.74n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226998
PNG
(US9328096, 686)
Show SMILES CNc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)cn1
Show InChI InChI=1S/C29H23ClFN7O2/c1-32-26-11-10-18(16-34-26)17-35-29(40)25-15-27(38(37-25)19-7-3-2-4-8-19)36-28(39)20-13-21(23(31)14-22(20)30)24-9-5-6-12-33-24/h2-16H,17H2,1H3,(H,32,34)(H,35,40)(H,36,39)
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PC sid
UniChem
US Patent
n/an/a 1.77n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226353
PNG
(US9328096, 46)
Show SMILES Clc1cc(Cl)c(cc1C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1cn[nH]c1)-c1ccccn1
Show InChI InChI=1S/C26H19Cl2N7O2/c27-20-11-21(28)19(10-18(20)22-8-4-5-9-29-22)25(36)33-24-12-23(26(37)30-13-16-14-31-32-15-16)34-35(24)17-6-2-1-3-7-17/h1-12,14-15H,13H2,(H,30,37)(H,31,32)(H,33,36)
PDB

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PC sid
UniChem
US Patent
n/an/a 1.81n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226346
PNG
(US9328096, 39)
Show SMILES Fc1cc(Cl)c(cc1-c1ncccc1F)C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1cn[nH]c1
Show InChI InChI=1S/C26H18ClF2N7O2/c27-19-10-21(29)18(24-20(28)7-4-8-30-24)9-17(19)25(37)34-23-11-22(26(38)31-12-15-13-32-33-14-15)35-36(23)16-5-2-1-3-6-16/h1-11,13-14H,12H2,(H,31,38)(H,32,33)(H,34,37)
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PC sid
UniChem
US Patent
n/an/a 1.94n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM227052
PNG
(US9328096, 740)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cncnc2)c(Cl)cc1Cl
Show InChI InChI=1S/C27H18Cl2FN7O2/c28-20-10-21(29)19(9-18(20)25-22(30)7-4-8-33-25)26(38)35-24-11-23(36-37(24)17-5-2-1-3-6-17)27(39)34-14-16-12-31-15-32-13-16/h1-13,15H,14H2,(H,34,39)(H,35,38)
PDB

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PC sid
UniChem
US Patent
n/an/a 2.02n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226514
PNG
(US9328096, 207)
Show SMILES Nc1cccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)n1
Show InChI InChI=1S/C28H20ClF2N7O2/c29-20-13-22(31)19(26-21(30)9-5-11-33-26)12-18(20)27(39)36-25-14-23(37-38(25)17-7-2-1-3-8-17)28(40)34-15-16-6-4-10-24(32)35-16/h1-14H,15H2,(H2,32,35)(H,34,40)(H,36,39)
PDB

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PC sid
UniChem
US Patent
n/an/a 2.06n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226999
PNG
(US9328096, 687)
Show SMILES Oc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)nc1
Show InChI InChI=1S/C28H20ClFN6O3/c29-22-13-23(30)21(24-8-4-5-11-31-24)12-20(22)27(38)34-26-14-25(35-36(26)18-6-2-1-3-7-18)28(39)33-15-17-9-10-19(37)16-32-17/h1-14,16,37H,15H2,(H,33,39)(H,34,38)
PDB

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PC sid
UniChem
US Patent
n/an/a 2.27n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226472
PNG
(US9328096, 165)
Show SMILES Cc1n[nH]c(C)c1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C27H20Cl2FN7O2/c1-14-24(15(2)35-34-14)33-27(39)22-13-23(37(36-22)16-7-4-3-5-8-16)32-26(38)18-11-17(19(28)12-20(18)29)25-21(30)9-6-10-31-25/h3-13H,1-2H3,(H,32,38)(H,33,39)(H,34,35)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.45n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226881
PNG
(US9328096, 574)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2ccno2)c(Cl)cc1Cl
Show InChI InChI=1S/C26H17Cl2FN6O3/c27-19-12-20(28)18(11-17(19)24-21(29)7-4-9-30-24)25(36)33-23-13-22(26(37)31-14-16-8-10-32-38-16)34-35(23)15-5-2-1-3-6-15/h1-13H,14H2,(H,31,37)(H,33,36)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.46n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226481
PNG
(US9328096, 174)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cn[nH]n2)c(Cl)cc1Cl
Show InChI InChI=1S/C25H17Cl2FN8O2/c26-18-10-19(27)17(9-16(18)23-20(28)7-4-8-29-23)24(37)32-22-11-21(25(38)30-12-14-13-31-35-33-14)34-36(22)15-5-2-1-3-6-15/h1-11,13H,12H2,(H,30,38)(H,32,37)(H,31,33,35)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.53n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226483
PNG
(US9328096, 176)
Show SMILES Fc1ccc(nc1)-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cn[nH]c2)c(Cl)cc1Cl
Show InChI InChI=1S/C26H18Cl2FN7O2/c27-20-9-21(28)19(8-18(20)22-7-6-16(29)14-30-22)25(37)34-24-10-23(26(38)31-11-15-12-32-33-13-15)35-36(24)17-4-2-1-3-5-17/h1-10,12-14H,11H2,(H,31,38)(H,32,33)(H,34,37)
PDB

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PC sid
UniChem
US Patent
n/an/a 2.60n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226992
PNG
(US9328096, 680)
Show SMILES Cc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)c(N)n1
Show InChI InChI=1S/C29H23ClFN7O2/c1-17-10-11-18(27(32)35-17)16-34-29(40)25-15-26(38(37-25)19-7-3-2-4-8-19)36-28(39)20-13-21(23(31)14-22(20)30)24-9-5-6-12-33-24/h2-15H,16H2,1H3,(H2,32,35)(H,34,40)(H,36,39)
PDB

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PC sid
UniChem
US Patent
n/an/a 2.65n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226487
PNG
(US9328096, 180)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cc[nH]n2)c(Cl)cc1Cl
Show InChI InChI=1S/C26H18Cl2FN7O2/c27-19-12-20(28)18(11-17(19)24-21(29)7-4-9-30-24)25(37)33-23-13-22(26(38)31-14-15-8-10-32-34-15)35-36(23)16-5-2-1-3-6-16/h1-13H,14H2,(H,31,38)(H,32,34)(H,33,37)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.80n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226807
PNG
(US9328096, 500)
Show SMILES Cc1n[nH]c(C)c1NC(=O)c1cc(NC(=O)c2cc(c(F)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C27H20ClF2N7O2/c1-14-24(15(2)35-34-14)33-27(39)22-13-23(37(36-22)16-7-4-3-5-8-16)32-26(38)17-11-18(21(30)12-19(17)28)25-20(29)9-6-10-31-25/h3-13H,1-2H3,(H,32,38)(H,33,39)(H,34,35)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.84n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226729
PNG
(US9328096, 422)
Show SMILES CC1(O)CCC(CC1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ccc(F)cn2)n(n1)-c1ccccc1
Show InChI InChI=1S/C29H26Cl2FN5O3/c1-29(40)11-9-18(10-12-29)34-28(39)25-15-26(37(36-25)19-5-3-2-4-6-19)35-27(38)21-13-20(22(30)14-23(21)31)24-8-7-17(32)16-33-24/h2-8,13-16,18,40H,9-12H2,1H3,(H,34,39)(H,35,38)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226458
PNG
(US9328096, 151)
Show SMILES Nc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)cn1
Show InChI InChI=1S/C28H20ClF2N7O2/c29-20-12-22(31)19(26-21(30)7-4-10-33-26)11-18(20)27(39)36-25-13-23(37-38(25)17-5-2-1-3-6-17)28(40)35-15-16-8-9-24(32)34-14-16/h1-14H,15H2,(H2,32,34)(H,35,40)(H,36,39)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226485
PNG
(US9328096, 178)
Show SMILES Fc1cc(Cl)c(cc1-c1ccccn1)C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1cn[nH]c1
Show InChI InChI=1S/C26H19ClFN7O2/c27-20-11-21(28)19(22-8-4-5-9-29-22)10-18(20)25(36)33-24-12-23(26(37)30-13-16-14-31-32-15-16)34-35(24)17-6-2-1-3-7-17/h1-12,14-15H,13H2,(H,30,37)(H,31,32)(H,33,36)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226347
PNG
(US9328096, 40)
Show SMILES Cc1n[nH]cc1NC(=O)c1cc(NC(=O)c2cc(c(F)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H18ClF2N7O2/c1-14-22(13-31-34-14)32-26(38)21-12-23(36(35-21)15-6-3-2-4-7-15)33-25(37)16-10-17(20(29)11-18(16)27)24-19(28)8-5-9-30-24/h2-13H,1H3,(H,31,34)(H,32,38)(H,33,37)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226882
PNG
(US9328096, 575)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cccnn2)c(Cl)cc1Cl
Show InChI InChI=1S/C27H18Cl2FN7O2/c28-20-13-21(29)19(12-18(20)25-22(30)9-5-10-31-25)26(38)34-24-14-23(36-37(24)17-7-2-1-3-8-17)27(39)32-15-16-6-4-11-33-35-16/h1-14H,15H2,(H,32,39)(H,34,38)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226874
PNG
(US9328096, 567)
Show SMILES Cn1cc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)nn1
Show InChI InChI=1S/C26H19Cl2FN8O2/c1-36-14-15(33-35-36)13-31-26(39)22-12-23(37(34-22)16-6-3-2-4-7-16)32-25(38)18-10-17(19(27)11-20(18)28)24-21(29)8-5-9-30-24/h2-12,14H,13H2,1H3,(H,31,39)(H,32,38)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM227058
PNG
(US9328096, 746)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCCC#N)c(Cl)cc1Cl
Show InChI InChI=1S/C25H17Cl2FN6O2/c26-18-13-19(27)17(12-16(18)23-20(28)8-4-10-30-23)24(35)32-22-14-21(25(36)31-11-5-9-29)33-34(22)15-6-2-1-3-7-15/h1-4,6-8,10,12-14H,5,11H2,(H,31,36)(H,32,35)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226529
PNG
(US9328096, 222)
Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(ccc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)ccn1
Show InChI InChI=1S/C28H21ClFN7O2/c29-21-9-8-18(26-22(30)7-4-11-33-26)14-20(21)27(38)35-25-15-23(36-37(25)19-5-2-1-3-6-19)28(39)34-16-17-10-12-32-24(31)13-17/h1-15H,16H2,(H2,31,32)(H,34,39)(H,35,38)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226838
PNG
(US9328096, 531)
Show SMILES OCC1(CC1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H20Cl2FN5O3/c27-18-12-19(28)17(11-16(18)23-20(29)7-4-10-30-23)24(36)31-22-13-21(25(37)32-26(14-35)8-9-26)33-34(22)15-5-2-1-3-6-15/h1-7,10-13,35H,8-9,14H2,(H,31,36)(H,32,37)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226445
PNG
(US9328096, 138)
Show SMILES Nc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)cn1
Show InChI InChI=1S/C28H21ClFN7O2/c29-21-13-22(30)20(23-8-4-5-11-32-23)12-19(21)27(38)35-26-14-24(36-37(26)18-6-2-1-3-7-18)28(39)34-16-17-9-10-25(31)33-15-17/h1-15H,16H2,(H2,31,33)(H,34,39)(H,35,38)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226521
PNG
(US9328096, 214)
Show SMILES Fc1cc(Cl)c(cc1-c1ncccc1F)C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1cnn[nH]1
Show InChI InChI=1S/C25H17ClF2N8O2/c26-18-10-20(28)17(23-19(27)7-4-8-29-23)9-16(18)24(37)32-22-11-21(25(38)30-12-14-13-31-35-33-14)34-36(22)15-5-2-1-3-6-15/h1-11,13H,12H2,(H,30,38)(H,32,37)(H,31,33,35)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226352
PNG
(US9328096, 45)
Show SMILES Cc1n[nH]cc1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ccccn2)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H19Cl2N7O2/c1-15-23(14-30-33-15)31-26(37)22-13-24(35(34-22)16-7-3-2-4-8-16)32-25(36)18-11-17(19(27)12-20(18)28)21-9-5-6-10-29-21/h2-14H,1H3,(H,30,33)(H,31,37)(H,32,36)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226865
PNG
(US9328096, 558)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NC2CC2)c(Cl)cc1Cl
Show InChI InChI=1S/C25H18Cl2FN5O2/c26-18-12-19(27)17(11-16(18)23-20(28)7-4-10-29-23)24(34)31-22-13-21(25(35)30-14-8-9-14)32-33(22)15-5-2-1-3-6-15/h1-7,10-14H,8-9H2,(H,30,35)(H,31,34)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226477
PNG
(US9328096, 170)
Show SMILES O[C@H]1CC[C@@H](CC1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C28H24Cl2FN5O3/c29-21-14-22(30)20(13-19(21)26-23(31)7-4-12-32-26)27(38)34-25-15-24(35-36(25)17-5-2-1-3-6-17)28(39)33-16-8-10-18(37)11-9-16/h1-7,12-16,18,37H,8-11H2,(H,33,39)(H,34,38)/t16-,18-
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226853
PNG
(US9328096, 546)
Show SMILES OCC1(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)COC1
Show InChI InChI=1S/C27H22Cl2FN5O4/c28-19-10-20(29)18(9-17(19)24-21(30)7-4-8-31-24)25(37)33-23-11-22(34-35(23)16-5-2-1-3-6-16)26(38)32-12-27(13-36)14-39-15-27/h1-11,36H,12-15H2,(H,32,38)(H,33,37)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226476
PNG
(US9328096, 169)
Show SMILES OC1(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)COC1
Show InChI InChI=1S/C26H20Cl2FN5O4/c27-18-10-19(28)17(9-16(18)23-20(29)7-4-8-30-23)24(35)32-22-11-21(25(36)31-12-26(37)13-38-14-26)33-34(22)15-5-2-1-3-6-15/h1-11,37H,12-14H2,(H,31,36)(H,32,35)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226879
PNG
(US9328096, 572)
Show SMILES OCCCNC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C25H20Cl2FN5O3/c26-18-13-19(27)17(12-16(18)23-20(28)8-4-9-29-23)24(35)31-22-14-21(25(36)30-10-5-11-34)32-33(22)15-6-2-1-3-7-15/h1-4,6-9,12-14,34H,5,10-11H2,(H,30,36)(H,31,35)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226862
PNG
(US9328096, 555)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)N[C@@H]2CCOC2)c(Cl)cc1Cl
Show InChI InChI=1S/C26H20Cl2FN5O3/c27-19-12-20(28)18(11-17(19)24-21(29)7-4-9-30-24)25(35)32-23-13-22(26(36)31-15-8-10-37-14-15)33-34(23)16-5-2-1-3-6-16/h1-7,9,11-13,15H,8,10,14H2,(H,31,36)(H,32,35)/t15-/m1/s1
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226845
PNG
(US9328096, 538)
Show SMILES O[C@H]1CC[C@H](CC1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C28H24Cl2FN5O3/c29-21-14-22(30)20(13-19(21)26-23(31)7-4-12-32-26)27(38)34-25-15-24(35-36(25)17-5-2-1-3-6-17)28(39)33-16-8-10-18(37)11-9-16/h1-7,12-16,18,37H,8-11H2,(H,33,39)(H,34,38)/t16-,18+
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM227054
PNG
(US9328096, 742)
Show SMILES CC(CO)CNC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H22Cl2FN5O3/c1-15(14-35)13-31-26(37)22-12-23(34(33-22)16-6-3-2-4-7-16)32-25(36)18-10-17(19(27)11-20(18)28)24-21(29)8-5-9-30-24/h2-12,15,35H,13-14H2,1H3,(H,31,37)(H,32,36)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM227000
PNG
(US9328096, 688)
Show SMILES COc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)ccn1
Show InChI InChI=1S/C29H22ClFN6O3/c1-40-27-13-18(10-12-33-27)17-34-29(39)25-16-26(37(36-25)19-7-3-2-4-8-19)35-28(38)20-14-21(23(31)15-22(20)30)24-9-5-6-11-32-24/h2-16H,17H2,1H3,(H,34,39)(H,35,38)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226441
PNG
(US9328096, 134)
Show SMILES CC(C)(C)CNC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C27H24Cl2FN5O2/c1-27(2,3)15-32-26(37)22-14-23(35(34-22)16-8-5-4-6-9-16)33-25(36)18-12-17(19(28)13-20(18)29)24-21(30)10-7-11-31-24/h4-14H,15H2,1-3H3,(H,32,37)(H,33,36)
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Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226856
PNG
(US9328096, 549)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCC2CCOC2)c(Cl)cc1Cl
Show InChI InChI=1S/C27H22Cl2FN5O3/c28-20-12-21(29)19(11-18(20)25-22(30)7-4-9-31-25)26(36)33-24-13-23(27(37)32-14-16-8-10-38-15-16)34-35(24)17-5-2-1-3-6-17/h1-7,9,11-13,16H,8,10,14-15H2,(H,32,37)(H,33,36)
PDB

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AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.66n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226494
PNG
(US9328096, 187)
Show SMILES Clc1cc(Cl)c(cc1C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1ccno1)-c1ccccn1
Show InChI InChI=1S/C26H18Cl2N6O3/c27-20-13-21(28)19(12-18(20)22-8-4-5-10-29-22)25(35)32-24-14-23(26(36)30-15-17-9-11-31-37-17)33-34(24)16-6-2-1-3-7-16/h1-14H,15H2,(H,30,36)(H,32,35)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.67n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226866
PNG
(US9328096, 559)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2ccncn2)c(Cl)cc1Cl
Show InChI InChI=1S/C27H18Cl2FN7O2/c28-20-12-21(29)19(11-18(20)25-22(30)7-4-9-32-25)26(38)35-24-13-23(36-37(24)17-5-2-1-3-6-17)27(39)33-14-16-8-10-31-15-34-16/h1-13,15H,14H2,(H,33,39)(H,35,38)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.68n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226850
PNG
(US9328096, 543)
Show SMILES O[C@H]1C[C@@H](C1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H20Cl2FN5O3/c27-19-12-20(28)18(11-17(19)24-21(29)7-4-8-30-24)25(36)32-23-13-22(26(37)31-14-9-16(35)10-14)33-34(23)15-5-2-1-3-6-15/h1-8,11-14,16,35H,9-10H2,(H,31,37)(H,32,36)/t14-,16-
PDB

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AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.69n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226465
PNG
(US9328096, 158)
Show SMILES Cc1ncc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)[nH]1
Show InChI InChI=1S/C27H20Cl2FN7O2/c1-15-32-13-16(34-15)14-33-27(39)23-12-24(37(36-23)17-6-3-2-4-7-17)35-26(38)19-10-18(20(28)11-21(19)29)25-22(30)8-5-9-31-25/h2-13H,14H2,1H3,(H,32,34)(H,33,39)(H,35,38)
PDB

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AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.71n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226460
PNG
(US9328096, 153)
Show SMILES O[C@@H]1COC[C@H]1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H20Cl2FN5O4/c27-17-10-18(28)16(9-15(17)24-19(29)7-4-8-30-24)25(36)32-23-11-20(26(37)31-21-12-38-13-22(21)35)33-34(23)14-5-2-1-3-6-14/h1-11,21-22,35H,12-13H2,(H,31,37)(H,32,36)/t21-,22-/m1/s1
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.72n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226877
PNG
(US9328096, 570)
Show SMILES C[C@@H](CO)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C25H20Cl2FN5O3/c1-14(13-34)30-25(36)21-12-22(33(32-21)15-6-3-2-4-7-15)31-24(35)17-10-16(18(26)11-19(17)27)23-20(28)8-5-9-29-23/h2-12,14,34H,13H2,1H3,(H,30,36)(H,31,35)/t14-/m0/s1
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.73n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


Citation and Details
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%