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Patent code US9346770

Compile Data Set for Download or QSAR
Found 29 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM232288
PNG
(US9346770, 1)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(F)cc2)ccc1CCC(O)=O
Show InChI InChI=1S/C23H24FNO4/c1-3-16-14-20(10-6-17(16)7-11-22(26)27)28-13-12-21-15(2)29-23(25-21)18-4-8-19(24)9-5-18/h4-6,8-10,14H,3,7,11-13H2,1-2H3,(H,26,27)
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US Patent
n/an/an/an/a 29n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM232295
PNG
(US9346770, 8)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C#N)ncc1CCC(O)=O
Show InChI InChI=1S/C23H23N3O4/c1-3-17-12-21(25-14-19(17)8-9-22(27)28)29-11-10-20-15(2)30-23(26-20)18-6-4-16(13-24)5-7-18/h4-7,12,14H,3,8-11H2,1-2H3,(H,27,28)
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n/an/an/an/a 6n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM232295
PNG
(US9346770, 8)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C#N)ncc1CCC(O)=O
Show InChI InChI=1S/C23H23N3O4/c1-3-17-12-21(25-14-19(17)8-9-22(27)28)29-11-10-20-15(2)30-23(26-20)18-6-4-16(13-24)5-7-18/h4-7,12,14H,3,8-11H2,1-2H3,(H,27,28)
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n/an/an/an/a 22n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM232288
PNG
(US9346770, 1)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(F)cc2)ccc1CCC(O)=O
Show InChI InChI=1S/C23H24FNO4/c1-3-16-14-20(10-6-17(16)7-11-22(26)27)28-13-12-21-15(2)29-23(25-21)18-4-8-19(24)9-5-18/h4-6,8-10,14H,3,7,11-13H2,1-2H3,(H,26,27)
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n/an/an/an/a 29n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM232292
PNG
(US9346770, 5)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(C)cc2)ccc1CCC(O)=O
Show InChI InChI=1S/C24H27NO4/c1-4-18-15-21(11-9-19(18)10-12-23(26)27)28-14-13-22-17(3)29-24(25-22)20-7-5-16(2)6-8-20/h5-9,11,15H,4,10,12-14H2,1-3H3,(H,26,27)
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n/an/an/an/a 4n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM232296
PNG
(US9346770, 9)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C(N)=O)ncc1CCC(O)=O
Show InChI InChI=1S/C23H25N3O5/c1-3-15-12-20(25-13-18(15)8-9-21(27)28)30-11-10-19-14(2)31-23(26-19)17-6-4-16(5-7-17)22(24)29/h4-7,12-13H,3,8-11H2,1-2H3,(H2,24,29)(H,27,28)
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n/an/an/an/a 331n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM232296
PNG
(US9346770, 9)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C(N)=O)ncc1CCC(O)=O
Show InChI InChI=1S/C23H25N3O5/c1-3-15-12-20(25-13-18(15)8-9-21(27)28)30-11-10-19-14(2)31-23(26-19)17-6-4-16(5-7-17)22(24)29/h4-7,12-13H,3,8-11H2,1-2H3,(H2,24,29)(H,27,28)
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n/an/an/an/a 47n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM232290
PNG
(US9346770, 3)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C(F)(F)F)ccc1CCC(O)=O
Show InChI InChI=1S/C24H24F3NO4/c1-3-16-14-20(10-6-17(16)7-11-22(29)30)31-13-12-21-15(2)32-23(28-21)18-4-8-19(9-5-18)24(25,26)27/h4-6,8-10,14H,3,7,11-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 4n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM232295
PNG
(US9346770, 8)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C#N)ncc1CCC(O)=O
Show InChI InChI=1S/C23H23N3O4/c1-3-17-12-21(25-14-19(17)8-9-22(27)28)29-11-10-20-15(2)30-23(26-20)18-6-4-16(13-24)5-7-18/h4-7,12,14H,3,8-11H2,1-2H3,(H,27,28)
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n/an/an/an/a 5.25E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM232296
PNG
(US9346770, 9)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C(N)=O)ncc1CCC(O)=O
Show InChI InChI=1S/C23H25N3O5/c1-3-15-12-20(25-13-18(15)8-9-21(27)28)30-11-10-19-14(2)31-23(26-19)17-6-4-16(5-7-17)22(24)29/h4-7,12-13H,3,8-11H2,1-2H3,(H2,24,29)(H,27,28)
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n/an/an/an/a 1.15E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM232293
PNG
(US9346770, 6)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)-c2nnn[nH]2)ccc1CCC(O)=O
Show InChI InChI=1S/C24H25N5O4/c1-3-16-14-20(10-8-17(16)9-11-22(30)31)32-13-12-21-15(2)33-24(25-21)19-6-4-18(5-7-19)23-26-28-29-27-23/h4-8,10,14H,3,9,11-13H2,1-2H3,(H,30,31)(H,26,27,28,29)
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US Patent
n/an/an/an/a 6.76E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM232289
PNG
(US9346770, 2)
Show SMILES CCc1cc(OCCc2coc(n2)-c2ccc(cc2)C(F)(F)F)ccc1CCC(O)=O
Show InChI InChI=1S/C23H22F3NO4/c1-2-15-13-20(9-5-16(15)6-10-21(28)29)30-12-11-19-14-31-22(27-19)17-3-7-18(8-4-17)23(24,25)26/h3-5,7-9,13-14H,2,6,10-12H2,1H3,(H,28,29)
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n/an/an/an/a 5.50E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM232293
PNG
(US9346770, 6)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)-c2nnn[nH]2)ccc1CCC(O)=O
Show InChI InChI=1S/C24H25N5O4/c1-3-16-14-20(10-8-17(16)9-11-22(30)31)32-13-12-21-15(2)33-24(25-21)19-6-4-18(5-7-19)23-26-28-29-27-23/h4-8,10,14H,3,9,11-13H2,1-2H3,(H,30,31)(H,26,27,28,29)
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n/an/an/an/a 2.63E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM232288
PNG
(US9346770, 1)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(F)cc2)ccc1CCC(O)=O
Show InChI InChI=1S/C23H24FNO4/c1-3-16-14-20(10-6-17(16)7-11-22(26)27)28-13-12-21-15(2)29-23(25-21)18-4-8-19(24)9-5-18/h4-6,8-10,14H,3,7,11-13H2,1-2H3,(H,26,27)
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n/an/an/an/a 13n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50030474
PNG
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Show SMILES CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1
Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)
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US Patent
n/an/an/an/a 5.25E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM232292
PNG
(US9346770, 5)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(C)cc2)ccc1CCC(O)=O
Show InChI InChI=1S/C24H27NO4/c1-4-18-15-21(11-9-19(18)10-12-23(26)27)28-14-13-22-17(3)29-24(25-22)20-7-5-16(2)6-8-20/h5-9,11,15H,4,10,12-14H2,1-3H3,(H,26,27)
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n/an/an/an/a 1.18E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM232291
PNG
(US9346770, 4)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C(C)(C)C)ccc1CCC(O)=O
Show InChI InChI=1S/C27H33NO4/c1-6-19-17-23(13-9-20(19)10-14-25(29)30)31-16-15-24-18(2)32-26(28-24)21-7-11-22(12-8-21)27(3,4)5/h7-9,11-13,17H,6,10,14-16H2,1-5H3,(H,29,30)
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n/an/an/an/a 89n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM232293
PNG
(US9346770, 6)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)-c2nnn[nH]2)ccc1CCC(O)=O
Show InChI InChI=1S/C24H25N5O4/c1-3-16-14-20(10-8-17(16)9-11-22(30)31)32-13-12-21-15(2)33-24(25-21)19-6-4-18(5-7-19)23-26-28-29-27-23/h4-8,10,14H,3,9,11-13H2,1-2H3,(H,30,31)(H,26,27,28,29)
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n/an/an/an/a 6.76E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM232292
PNG
(US9346770, 5)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(C)cc2)ccc1CCC(O)=O
Show InChI InChI=1S/C24H27NO4/c1-4-18-15-21(11-9-19(18)10-12-23(26)27)28-14-13-22-17(3)29-24(25-22)20-7-5-16(2)6-8-20/h5-9,11,15H,4,10,12-14H2,1-3H3,(H,26,27)
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n/an/an/an/a 7n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM232291
PNG
(US9346770, 4)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C(C)(C)C)ccc1CCC(O)=O
Show InChI InChI=1S/C27H33NO4/c1-6-19-17-23(13-9-20(19)10-14-25(29)30)31-16-15-24-18(2)32-26(28-24)21-7-11-22(12-8-21)27(3,4)5/h7-9,11-13,17H,6,10,14-16H2,1-5H3,(H,29,30)
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n/an/an/an/a 5.50E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM232289
PNG
(US9346770, 2)
Show SMILES CCc1cc(OCCc2coc(n2)-c2ccc(cc2)C(F)(F)F)ccc1CCC(O)=O
Show InChI InChI=1S/C23H22F3NO4/c1-2-15-13-20(9-5-16(15)6-10-21(28)29)30-12-11-19-14-31-22(27-19)17-3-7-18(8-4-17)23(24,25)26/h3-5,7-9,13-14H,2,6,10-12H2,1H3,(H,28,29)
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n/an/an/an/a 692n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM232289
PNG
(US9346770, 2)
Show SMILES CCc1cc(OCCc2coc(n2)-c2ccc(cc2)C(F)(F)F)ccc1CCC(O)=O
Show InChI InChI=1S/C23H22F3NO4/c1-2-15-13-20(9-5-16(15)6-10-21(28)29)30-12-11-19-14-31-22(27-19)17-3-7-18(8-4-17)23(24,25)26/h3-5,7-9,13-14H,2,6,10-12H2,1H3,(H,28,29)
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n/an/an/an/a<1n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM232290
PNG
(US9346770, 3)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C(F)(F)F)ccc1CCC(O)=O
Show InChI InChI=1S/C24H24F3NO4/c1-3-16-14-20(10-6-17(16)7-11-22(29)30)31-13-12-21-15(2)32-23(28-21)18-4-8-19(9-5-18)24(25,26)27/h4-6,8-10,14H,3,7,11-13H2,1-2H3,(H,29,30)
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n/an/an/an/a<1n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM232291
PNG
(US9346770, 4)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C(C)(C)C)ccc1CCC(O)=O
Show InChI InChI=1S/C27H33NO4/c1-6-19-17-23(13-9-20(19)10-14-25(29)30)31-16-15-24-18(2)32-26(28-24)21-7-11-22(12-8-21)27(3,4)5/h7-9,11-13,17H,6,10,14-16H2,1-5H3,(H,29,30)
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n/an/an/an/a 851n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM232294
PNG
(US9346770, 7)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)N(=O)=O)ncc1CCC(O)=O
Show InChI InChI=1S/C22H23N3O6/c1-3-15-12-20(23-13-17(15)6-9-21(26)27)30-11-10-19-14(2)31-22(24-19)16-4-7-18(8-5-16)25(28)29/h4-5,7-8,12-13H,3,6,9-11H2,1-2H3,(H,26,27)
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n/an/an/an/a 2.88E+3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM232294
PNG
(US9346770, 7)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)N(=O)=O)ncc1CCC(O)=O
Show InChI InChI=1S/C22H23N3O6/c1-3-15-12-20(23-13-17(15)6-9-21(26)27)30-11-10-19-14(2)31-22(24-19)16-4-7-18(8-5-16)25(28)29/h4-5,7-8,12-13H,3,6,9-11H2,1-2H3,(H,26,27)
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n/an/an/an/a 25n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50030474
PNG
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Show SMILES CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1
Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)
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n/an/an/an/a 1n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM232294
PNG
(US9346770, 7)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)N(=O)=O)ncc1CCC(O)=O
Show InChI InChI=1S/C22H23N3O6/c1-3-15-12-20(23-13-17(15)6-9-21(26)27)30-11-10-19-14(2)31-22(24-19)16-4-7-18(8-5-16)25(28)29/h4-5,7-8,12-13H,3,6,9-11H2,1-2H3,(H,26,27)
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n/an/an/an/a 3n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM232290
PNG
(US9346770, 3)
Show SMILES CCc1cc(OCCc2nc(oc2C)-c2ccc(cc2)C(F)(F)F)ccc1CCC(O)=O
Show InChI InChI=1S/C24H24F3NO4/c1-3-16-14-20(10-6-17(16)7-11-22(29)30)31-13-12-21-15(2)32-23(28-21)18-4-8-19(9-5-18)24(25,26)27/h4-6,8-10,14H,3,7,11-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 5n/an/an/an/a



ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%