Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 8045
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155565(US10092556, Example 1 | US9012475, 1 | US9346787, ...)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155568(US10092556, Example 12 | US9012475, 12 | US9346787...)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155569(US10092556, Example 13 | US9012475, 13 | US9346787...)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155574(US10092556, Example 24 | US9012475, 24 | US9346787...)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155566(US10092556, Example 2 | US9012475, 2 | US9346787, ...)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155567(US10092556, Example 11 | US9012475, 11 | US9346787...)
Affinity DataIC50:  0.600nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)
Affinity DataIC50:  0.600nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155575(US10092556, Example 28 | US9012475, 28 | US9346787...)
Affinity DataIC50:  0.700nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155573(US10092556, Example 22 | US9012475, 22 | US9346787...)
Affinity DataIC50:  0.700nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155576(US10092556, Example 29 | US9012475, 29 | US9346787...)
Affinity DataIC50:  0.800nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US10092556, Example 17 | US9012475, 17 | US9346787...)
Affinity DataIC50:  0.900nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155570(US10092556, Example 14 | US9012475, 14 | US9346787...)
Affinity DataIC50:  0.900nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155572(US10092556, Example 19 | US9012475, 19 | US9346787...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)
Affinity DataIC50:  90nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155565(US10092556, Example 1 | US9012475, 1 | US9346787, ...)
Affinity DataIC50:  140nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155569(US10092556, Example 13 | US9012475, 13 | US9346787...)
Affinity DataIC50:  180nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155574(US10092556, Example 24 | US9012475, 24 | US9346787...)
Affinity DataIC50:  190nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM231252(US10092556, Comparative Example 6 | US9346787, Com...)
Affinity DataIC50:  220nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155568(US10092556, Example 12 | US9012475, 12 | US9346787...)
Affinity DataIC50:  260nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM231252(US10092556, Comparative Example 6 | US9346787, Com...)
Affinity DataIC50:  320nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155566(US10092556, Example 2 | US9012475, 2 | US9346787, ...)
Affinity DataIC50:  340nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155573(US10092556, Example 22 | US9012475, 22 | US9346787...)
Affinity DataIC50:  380nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155576(US10092556, Example 29 | US9012475, 29 | US9346787...)
Affinity DataIC50:  390nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155575(US10092556, Example 28 | US9012475, 28 | US9346787...)
Affinity DataIC50:  450nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155570(US10092556, Example 14 | US9012475, 14 | US9346787...)
Affinity DataIC50:  460nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155572(US10092556, Example 19 | US9012475, 19 | US9346787...)
Affinity DataIC50:  680nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US10092556, Example 17 | US9012475, 17 | US9346787...)
Affinity DataIC50:  900nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155567(US10092556, Example 11 | US9012475, 11 | US9346787...)
Affinity DataIC50:  930nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent